Chromatography and Mass Spectrometry: Evolving Techniques for Food Analysis
1. Introduction
2. Overview of Published Articles
2.1. Application of Chromatography and Mass Spectrometry in Food Analysis
2.2. Emerging Tools in Food Analysis
2.3. Trends in Analytical Extraction
3. Future Perspectives
Conflicts of Interest
List of Contributions
- Carabetta, S.; Di Sanzo, R.; Fuda, S.; Muscolo, A.; Russo, M. A Predictive Model to Correlate Amino Acids and Aromatic Compounds in Calabrian Honeys. Foods 2023, 12, 3284. http://doi.org/10.3390/foods12173284.
- Krusinski, L.; Maciel, I.C.F.; van Vliet, S.; Ahsin, M.; Lu, G.; Rowntree, J.E.; Fenton, J.I. Measuring the Phytochemical Richness of Meat: Effects of Grass/Grain Finishing Systems and Grapeseed Extract Supplementation on the Fatty Acid and Phytochemical Content of Beef. Foods 2023, 12, 3547. http://doi.org/10.3390/foods12193547.
- Wu, L.; Wang, X.; Hao, J.; Zhu, N.; Wang, M. Geographical Indication Characteristics of Aroma and Phenolic Acids of the Changping Strawberry. Foods 2023, 12, 3889. http://doi.org/10.3390/foods12213889.
- Maurício, T.; Couto, D.; Lopes, D.; Conde, T.; Pais, R.; Batista, J.; Melo, T.; Pinho, M.; Moreira, A.S.P.; Trovão, M.; et al. Differences and Similarities in Lipid Composition, Nutritional Value, and Bioactive Potential of Four Edible Chlorella vulgaris Strains. Foods 2023, 12, 1625. http://doi.org/10.3390/foods12081625.
- Zong, X.; Lei, N.; Yin, J.; He, W.; Nie, S.; Xie, M. Exploration and Improvement of Acid Hydrolysis Conditions for Inulin-Type Fructans Monosaccharide Composition Analysis: Monosaccharide Recovery and By-Product Identification. Foods 2024, 13, 1241. http://doi.org/10.3390/foods13081241.
- Prasongdee, P.; Posridee, K.; Oonsivilai, A.; Oonsivilai, R. A Culinary and Medicinal Gem: Exploring the Phytochemical and Functional Properties of Thai Basil. Foods 2024, 13, 632. http://doi.org/10.3390/foods13040632.
- Yévenes, K.; Ibáñez, M.J.; Pokrant, E.; Flores, A.; Maturana, M.; Maddaleno, A.; Cornejo, J. A Suitable HPLC-MS/MS Methodology for the Detection of Oxytetracycline, Enrofloxacin, and Sulfachloropyridazine Residues in Lettuce Plants. Foods 2024, 13, 153.
- Nevistić, M.B.; Tomas, M.K. Matrix Effect Evaluation in GC/MS-MS Analysis of Multiple Pesticide Residues in Selected Food Matrices. Foods 2023, 12, 3991.
- Kim, M.C.; Park, S.Y.; Kwon, S.Y.; Kim, Y.K.; Kim, Y.I.; Seo, Y.S.; Cho, S.M.; Shin, E.C.; Mok, J.H.; Lee, Y.B. Application of Static Headspace GC-MS Method for Selective 1,4-Dioxane Detection in Food Additives. Foods 2023, 12, 3299. http://doi.org/10.3390/foods12173299.
References
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- Sun, Q.; Dong, Y.; Wen, X.; Zhang, X.; Hou, S.; Zhao, W.; Yin, D. A Review on Recent Advances in Mass Spectrometry Analysis of Harmful Contaminants in Food. Front. Nutr. 2023, 10, 1244459. [Google Scholar] [CrossRef] [PubMed]
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Sample | Goal | Chromatographic Technique | Main Outcomes | C |
---|---|---|---|---|
Calabrian unifloral honeys | To develop a predictive model correlating amino acids to volatile aroma compounds. | UHPLC-ESI-MS/MS (Triple Quad MS) HS-SPME-GC-MS |
| 1 |
Beef samples resulting from cattle fed with:
| To compare fatty acid, micronutrient, and phytochemical composition. | GC-MS; UPLC-MS/MS (Triple Quad MS) |
| 2 |
Autotrophic (C-Auto) and heterotrophic (C-Hetero) Chlorella vulgaris strains Chlorophyll-deficient mutants (C-White and C-Honey) | To assess fatty acid (FA) and lipid profile; to evaluate their antioxidant and anti-inflammatory properties. | GC-FID; LC-MS/MS (hybrid quadrupole Orbitrap MS) |
| 3 |
Inulin-type fructan (ITF) | To maximize the recovery of monosaccharides and find non-sugar byproducts from the hydrolysis of ITF by optimizing the acid hydrolysis conditions (acid concentration, temperature, and time). | UPLC-Triple-TOF/MS |
| 4 |
Geographical indication certified (GI) and non-GI strawberries | To compare the aroma and phenolic acid composition. | GC–MS UHPLC–MS/MS (Triple Quad MS) |
| 5 |
Water, ethanol, and ethyl acetate extracts of Thai basil: Ocimum basilicum var. thyrsiflorum and O. basilicum cv.Jumbo 4320 | To evaluate the phytochemical profile and antioxidant, antimicrobial, antithrombotic, and cytotoxic activities. | HPLC-PDA |
| 6 |
Lettuce | To implement and validate a method for the detection of residues of oxytetracycline (OTC), 4-epi-oxitetracycline (4-epi-OTC), enrofloxacin (EFX), sulfachloropyridazine (SCP), and ciprofloxacin (CFX), and the detection of these drug residues in commercially available lettuce. | HPLC-MS/MS (QTRAP MS) |
| 7 |
Apples, grapes, spelt kernels, and sunflower seeds | To determine the matrix effects during the analysis of more than 200 pesticide residues using QuEChERS sample preparation. | GC-MS/MS |
| 8 |
Polyethylene glycol 600 (PEG 600) | To develop and validate a method for quantitating trace 1,4-dioxane in food additive matrices. | Static headspace (SH) GC-MS |
| 9 |
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Bento da Silva, A.; Duarte, N. Chromatography and Mass Spectrometry: Evolving Techniques for Food Analysis. Foods 2025, 14, 2694. https://doi.org/10.3390/foods14152694
Bento da Silva A, Duarte N. Chromatography and Mass Spectrometry: Evolving Techniques for Food Analysis. Foods. 2025; 14(15):2694. https://doi.org/10.3390/foods14152694
Chicago/Turabian StyleBento da Silva, Andreia, and Noélia Duarte. 2025. "Chromatography and Mass Spectrometry: Evolving Techniques for Food Analysis" Foods 14, no. 15: 2694. https://doi.org/10.3390/foods14152694
APA StyleBento da Silva, A., & Duarte, N. (2025). Chromatography and Mass Spectrometry: Evolving Techniques for Food Analysis. Foods, 14(15), 2694. https://doi.org/10.3390/foods14152694