Search Results (95)

Sustainable aviation fuel (SAF) is a drop-in alternative to conventional jet fuels, designed to reduce greenhouse gas (GHG) emissions while requiring minimal infrastructure changes and certification under the American Society for Testing and Materials (ASTM) D7566 standard. This study assesses recently identified high-energy-density (HED) strained polycycloalkanes as SAF candidates. Strain energy (E_se) was calculated using density functional theory (DFT), while operational properties such as boiling point (BP) and flash point (FP) were predicted using support vector regression (SVR) models. The models demonstrated strong predictive performance (R² > 0.96) with mean absolute errors of 6.92 K for BP and 9.58 K for FP, with robustness sensitivity analysis. It is found that approximately 65% of these studied polycycloalkanes fall within the Jet A fuel property boundaries. The polycycloalkanes (C₉–C₁₅) with strain energies below approximately 60 kcal/mol achieve an balance between energy density and ignition safety, aligning with the specifications of Jet A. The majority of structures were dominated by five-membered rings, with a few three- or four-membered rings enhancing favorable trade-offs among BP, FP, and HED. This early pre-screening indicates that moderately strained polycycloalkanes are safe, energy-dense candidates for next-generation sustainable jet fuels and provide a framework for designing high-performance SAFs. Full article

Accurate classification of tree species is crucial for forest management and biodiversity conservation. Remote sensing technology offers a unique capability for classifying and mapping trees across large areas; however, the accuracy of extracting and identifying individual trees remains challenging due to the limitations of available imagery and phenological variations. This study presents a novel integrated machine learning (ML) and Geographic Object-Based Image Analysis (GEOBIA) framework to enhance tree species classification in a botanical garden using multi-temporal unmanned aerial vehicle (UAV) imagery. High-resolution UAV imagery (2.3 cm/pixel) was acquired across four different seasons (summer, autumn, winter, and early spring) to incorporate the phenological changes. Spectral, textural, geometrical, and canopy height features were extracted using GEOBIA and then evaluated with four ML models (Random Forest (RF), Extra Trees (ET), eXtreme gradient boost (XGBoost), and Support Vector Machine (SVM)). Multi-temporal data significantly outperformed single-date imagery, with RF achieving the highest overall accuracy (86%, F1-score 0.85, kappa 0.83) compared to 57–75% for single-date classifications. Canopy height and textural features were dominant for species identification, indicating the importance of structural variations. Despite the limitations of moderate sample size and a controlled botanical garden setting, this approach offers a robust framework for forest and urban landscape managers as well as remote sensing professionals, by optimizing UAV-based strategies for precise tree species identification and mapping to support urban and natural forest conservation. Full article

This paper addresses the challenges encountered by grid-connected photovoltaic (PV) systems, including the stochastic behavior of the system, harmonic distortion, and variations in grid impedance. To this end, an in-depth technical and pedagogical analysis of three linear multivariable current control strategies is performed: proportional-integral (PI), proportional-resonant (PR), and deadbeat (DB). The study contributes to theoretical formulations, detailed system modeling, and controller tuning procedures, promoting a comprehensive understanding of their structures and performance. The strategies are investigated and compared in both the rotating ($dq$) and stationary ($\alpha \beta$) reference frames, offering a broad perspective on system behavior under various operating conditions. Additionally, an in-depth analysis of the PR controller is presented, highlighting its potential to regulate both positive- and negative-sequence components. This enables the development of more effective and robust tuning methodologies for steady-state and dynamic scenarios. The evaluation is conducted under three main conditions: steady-state operation, transient response to input power variations, and robustness analysis in the presence of grid parameter changes. The study examines the impact of each controller on the total harmonic distortion (THD) of the injected current, as well as on system stability margins and dynamic performance. Practical aspects that are often overlooked are also addressed, such as the modeling of the inverter and photovoltaic generator, the implementation of space vector pulse-width modulation (SVPWM), and the influence of the output LC filter capacitor. The control structures under analysis are validated through numerical simulations performed in MatLab^® software (R2021b) using dedicated computational routines, enabling the identification of strategies that enhance performance and ensure compliance of grid-connected photovoltaic systems. Full article

With the exponential growth of textual data, traditional topic modeling methods based on static analysis demonstrate limited effectiveness in tracking the dynamics of thematic content. This research aims to develop a method for quantifying the dynamics of topics within text corpora using a thematic signal (TS) function that accounts for temporal changes and semantic relationships. The proposed method combines associative tokens with original lexical units to reduce thematic entropy and information noise. Approaches employed include topic modeling (LDA), vector representations of texts (TF-IDF, Word2Vec), and time series analysis. The method was tested on a corpus of news texts (5000 documents). Results demonstrated robust identification of semantically meaningful thematic clusters. An inverse relationship was observed between the level of thematic significance and semantic diversity, confirming a reduction in entropy using the proposed method. This approach allows for quantifying topic dynamics, filtering noise, and determining the optimal number of clusters. Future applications include analyzing multilingual data and integration with neural network models. The method shows potential for monitoring information flows and predicting thematic trends. Full article

Background: Parkinson’s disease (PD) is the second most common neurodegenerative disorder after Alzheimer’s disease, affecting countless individuals worldwide. PD is characterized by the onset of a marked motor symptomatology in association with several non-motor manifestations. The clinical phase of the disease is usually preceded by a long prodromal phase, devoid of overt motor symptomatology but often showing some conditions such as sleep disturbance, constipation, anosmia, and phonatory changes. To date, speech analysis appears to be a promising digital biomarker to anticipate even 10 years before the onset of clinical PD, as well serving as a useful prognostic tool for patient follow-up. That is why, the voice can be nominated as the non-invasive method to detect PD from healthy subjects (HS). Methods: Our study was based on cross-sectional study to analysis voice impairment. A dataset comprising 81 voice samples (41 from healthy individuals and 40 from PD patients) was utilized to train and evaluate common machine learning (ML) models using various types of features, including long-term (jitter, shimmer, and cepstral peak prominence (CPP)), short-term features (Mel-frequency cepstral coefficient (MFCC)), and non-standard measurements (pitch period entropy (PPE) and recurrence period density entropy (RPDE)). The study adopted multiple machine learning (ML) algorithms, including random forest (RF), K-nearest neighbors (KNN), decision tree (DT), naïve Bayes (NB), support vector machines (SVM), and logistic regression (LR). Cross-validation technique was applied to ensure the reliability of performance metrics on train and test subsets. These metrics (accuracy, recall, and precision), help determine the most effective models for distinguishing PD from healthy subjects. Result: Among all the algorithms used in this research, random forest (RF) was the best-performing model, achieving an accuracy of 82.72% with a ROC-AUC score of 89.65%. Although other models, such as support vector machine (SVM), could be considered with an accuracy of 75.29% and a ROC-AUC score of 82.63%, RF was by far the best one when evaluated across all metrics. The K-nearest neighbor (KNN) and decision tree (DT) performed the worst. Notably, by combining a comprehensive set of long-term, short-term, and non-standard acoustic features, unlike previous studies that typically focused on only a subset, our study achieved higher predictive performance, offering a more robust model for early PD detection. Conclusions: This study highlights the potential of combining advanced acoustic analysis with ML algorithms to develop non-invasive and reliable tools for early PD detection, offering substantial benefits for the healthcare sector. Full article

This study proposes an automatic gear shift classification algorithm in M1 category vehicles using data acquired through the onboard diagnostic system (OBD II) and GPS. The proposed approach is based on the analysis of identification parameters (PIDs), such as manifold absolute pressure (MAP), revolutions per minute (RPM), vehicle speed (VSS), torque, power, stall times, and longitudinal dynamics, to determine the efficiency and behavior of the vehicle in each of its gears. In addition, the unsupervised K-means algorithm was implemented to analyze vehicle gear changes, identify driving patterns, and segment the data into meaningful groups. Machine learning techniques, including K-Nearest Neighbors (KNN), decision trees, logistic regression, and Support Vector Machines (SVMs), were employed to classify gear shifts accurately. After a thorough evaluation, the KNN (Fine KNN) model proved to be the most effective, achieving an accuracy of 99.7%, an error rate of 0.3%, a precision of 99.8%, a recall of 99.7%, and an F1-score of 99.8%, outperforming other models in terms of accuracy, robustness, and balance between metrics. A multiple linear regression model was developed to estimate instantaneous fuel consumption (in L/100 km) using the gear predicted by the KNN algorithm and other relevant variables. The model, built on over 66,000 valid observations, achieved an R² of 0.897 and a root mean square error (RMSE) of 2.06, indicating a strong fit. Results showed that higher gears (3, 4, and 5) are associated with lower fuel consumption. In contrast, a neutral gear presented the highest levels of consumption and variability, especially during prolonged idling periods in heavy traffic conditions. In future work, we propose integrating this algorithm into driver assistance systems (ADAS) and exploring its applicability in autonomous vehicles to enhance real-time decision making. Such integration could optimize gear shift timing based on dynamic factors like road conditions, traffic density, and driver behavior, ultimately contributing to improved fuel efficiency and overall vehicle performance. Full article

Background/Objectives: Death-associated protein kinase 1 (DAPK1) is a serine/threonine kinase that plays a crucial role in cancer by regulating apoptosis through interactions with TP53. Aberrant expression of DAPK1 was shown in certain types of human cancer contributing to tumor progression and chemoresistance. This study aimed to investigate the role of DAPK1 in high-grade serous ovarian cancer (HGSOC) and to evaluate the therapeutic potential of restoring its kinase activity, including the use of truncated DAPK1 variants, to overcome chemoresistance and enhance tumor suppression. Methods: Gene expression analysis was performed on ovarian cancer tissues compared to benign controls to assess DAPK1 downregulation and its epigenetic regulation. Prognostic relevance was evaluated in a cohort of 1436 HGSOC patient samples. Functional restoration of DAPK1 was conducted in HGSOC cell lines and patient-derived primary tumor cells using vector-based expression or in vitro-transcribed (IVT) DAPK1 mRNA, including the application of truncated DAPK1 (ΔDAPK1) forms. To assess apoptosis, Caspase activation assays, 2D-colony formation assays, and cell survival assays were performed. To analyze the reactivation of DAPK1 downstream signaling, phosphorylation of p53 at Ser20 and the expression of p53 target proteins were examined. Chemosensitivity to Paclitaxel and Cisplatin was quantified by changes in IC₅₀ values. Results: DAPK1 expression was significantly downregulated in ovarian cancer compared to benign tissue, correlating with epigenetic silencing, and showed prognostic value in early-stage HGSOC. Restoration of DAPK1 activity, including ΔDAPK1 variants, led to phosphorylation of p53 Ser20, increased expression of p53 target proteins, and Caspase-dependent apoptosis. Reactivation of DAPK1 sensitized both established HGSOC cell lines and patient-derived ascites cells to Paclitaxel and Cisplatin. These effects occurred through both p53-dependent and p53-independent pathways, enabling robust tumor suppression even in p53-mutant contexts. Conclusions: Reactivation of DAPK1, particularly through truncated variants, represents a promising therapeutic strategy to overcome chemoresistance in HGSOC. The dual mechanisms of tumor suppression provide a strong rationale for developing DAPK1-based therapies to enhance the efficacy of standard chemotherapy, especially in patients with chemoresistant or p53-deficient tumors. Future work should focus on optimizing delivery approaches for DAPK1 variants and assessing their synergistic potential with emerging targeted treatments in clinical settings. Full article

This study investigated the dynamic factors influencing food security in Saudi Arabia, a critical concern for the nation’s stability and development. The purpose of this research was to analyze the impact of several key determinants on the Food Security Index and to distinguish between their short-term and long-term effects, thereby providing evidence-based policy recommendations. Using annual time-series data spanning 1990 to 2023, the research employs the Autoregressive Distributed Lag (ARDL) and Vector Error Correction Model (VECM) methods. We specifically examined the roles of agricultural GDP contribution, agricultural insurance coverage, food price stability, government policies related to agriculture, climate change impacts, agricultural productivity, and technology adoption. Short-run estimates reveal that agricultural GDP contribution, government policies, and agricultural productivity express a significant positive influence on food security. Importantly, climate change showed a counterintuitive positive association in the short term, potentially indicating immediate adaptive responses. Conversely, food price stability exhibited an unexpected negative association, which may indicate that the index captures high price levels rather than just volatility. The long-run analysis highlights the crucial importance of sustained factors for food security. Agricultural GDP contribution, agricultural insurance coverage, and agricultural productivity are identified as having significant positive impacts over the long term. In contrast, climate change demonstrates a significant negative long-run impact, underscoring its detrimental effect over time. Government policies, while impactful in the short term, become statistically insignificant in the long run, suggesting that sustained structural factors become dominant. Granger causality tests indicate short-term causal relationships flowing from climate change (positively), agricultural GDP contribution, government policies, and agricultural productivity towards food security. The significant error correction term confirms the existence of a stable long-run equilibrium relationship among the variables. On the basis of these findings, the study concludes that strengthening food security in Saudi Arabia requires a multifaceted approach. Short-term efforts should focus on enhancing agricultural productivity and implementing targeted measures to mitigate immediate climate impacts and refine food price stabilization strategies. For long-term resilience, priorities must include expanding agricultural insurance coverage, investing in sustainable agricultural practices, and continuing to boost agricultural productivity. The study contributes to the literature by providing a comprehensive dynamic analysis of food security determinants in Saudi Arabia using robust time-series methods, offering specific insights into the varying influences of economic, policy, environmental, and agricultural factors across different time horizons. Further research is recommended to explore the specific mechanisms behind the observed short-term relationship with climate change and optimize food price policies. Full article

Gravity anomalies play critical roles in geological analysis, geodynamic monitoring, and precise geoid modeling. Obtaining accurate gravity data is challenging, particularly in inaccessible or sparsely covered regions. This study evaluates machine learning (ML) methods—Support Vector Regression (SVR), Gaussian Process Regression (GPR), and Ensemble of Trees—for predicting gravity anomalies in southeastern Kazakhstan and compares their effectiveness with traditional Kriging interpolation. A dataset, consisting of the simple Bouguer anomaly values, latitude, longitude, elevation, normal gravity, and terrain corrections derived from historical maps at a scale of 1:200,000, was utilized. Models were trained and validated using cross-validation techniques, with performance assessed by statistical metrics (RMSE, MAE, R²) and spatial error analysis. Results indicated that the Exponential GPR model demonstrated the highest predictive accuracy, outperforming other ML methods, with 72.9% of predictions having errors below 1 mGal. Kriging showed comparable accuracy and superior robustness against extreme errors. Most prediction errors from all methods were spatially associated with mountainous regions featuring significant elevation changes. While this study demonstrated the effectiveness of machine learning methods for gravity anomaly prediction, their accuracy decreases in complex terrain, indicating the need for further research to improve model performance in such environments. Full article

Climate change presents significant challenges due to the increasing frequency and intensity of extreme weather events. Mexico, with its diverse climate and geographic position, is particularly vulnerable, underscoring the need for robust strategies to predict atmospheric variables. This work presents TAE Predict (Time series Analysis and Ensemble-based Prediction with relevant feature selection) based on relevant feature selection and ensemble models of machine learning. Dimensionality in multivariate time series is reduced through Principal Component Analysis, ensuring interpretability and efficiency. Additionally, data remediation techniques improve data set quality. The ensemble combines Long Short-Term Memory neural networks, Random Forest regression, and Support Vector Machines, optimizing their contributions using heuristic algorithms such as Particle Swarm Optimization. Experimental results from meteorological time series in key Mexican cities demonstrate that the proposed strategy outperforms individual models in accuracy and robustness. This methodology provides a replicable framework for climate variable forecasting, delivering analytical tools that support decision-making in critical sectors, such as agriculture and water resource management. The findings highlight the potential of integrating modern techniques to address complex, high-dimensional problems. By combining advanced prediction models and feature selection strategies, this study advances the reliability of climate forecasts and contributes to the development of effective adaptation and mitigation measures in response to climate change challenges. Full article

The intensification of global climate change, combined with increasing human activities, has significantly increased wildfire frequency and severity, posing a major global environmental challenge. As an illustration, Guizhou Province in China encountered a total of 221 wildfires over a span of 12 days. Despite significant advancements in wildfire prediction models, challenges related to data imbalance and model interpretability persist, undermining their overall reliability. In response to these challenges, this study proposes an explainable wildfire risk prediction model (EWXS) leveraging Extreme Gradient Boosting (XGBoost), with a focus on Guizhou Province. The methodology involved converting raster and vector data into structured tabular formats, merging, normalizing, and encoding them using the Weight of Evidence (WOE) technique to enhance feature representation. Subsequently, the cleaned data were balanced to establish a robust foundation for the EWXS model. The performance of the EWXS model was evaluated in comparison to established models, such as CatBoost, using a range of performance metrics. The results indicated that the EWXS model achieved an accuracy of 99.22%, precision of 98.48%, recall of 96.82%, an F1 score of 97.64%, and an AUC of 0.983, thereby demonstrating its strong performance. Moreover, the SHAP framework was employed to enhance model interpretability, unveiling key factors influencing wildfire risk, including proximity to villages, meteorological conditions, air humidity, and variations in vegetation temperature. This analysis provides valuable support for decision-making bodies by offering clear, explanatory insights into the factors contributing to wildfire risk. Full article

As human labour is limited and therefore expensive, computer vision has emerged as a solution with encouraging results for monitoring and sorting tasks in the agrifood sector, where conventional methods for inspecting fruit browning that are generally subjective, time-consuming, and costly. Thus, this study investigated the application of computer vision techniques and various RGB cameras in the detection and classification of enzymatic browning in cut pears, comparing convolutional neural networks (CNNs) with stochastic modelling. More specifically, light is shed on the potential of CNN-based approaches for high-throughput and easily adapted applications and the potential of stochastic methods for precise, quantitative analyses. In particular, the developed CNN model was easily trained and achieved an accuracy of 96.6% and an F1-score greater than 0.96 during testing with real pear slices. On the other hand, stochastic modelling provided quantitative indices (i.e., the Browning Index (BI) and Yellowing Index (YI)) derived from the CIE Lab* colour model, thus offering accurate monitoring of enzymatic browning and related optical changes but it was less versatile as it required human expertise for implementation and tuning. Using both the BI and YI as input vectors in the NN Bayesian classifier increased the correct classification rate of control samples to 82.85% (4.6% increase) and to 89.81% (15% increase) for treated samples. Finally, a future need for a hybrid approach combining the strengths of both methods was identified, with improved robustness and practicality of image analysis systems in agricultural quality control to enable higher levels of automation in this area. Full article

Progressive deterioration and accumulated damage due to overloading, extreme events, and fatigue necessitate the continuous monitoring of civil infrastructure to ensure serviceability and safety. With advances in sensor technology, data-driven structural health monitoring (SHM) strategies, particularly artificial neural networks (ANNs), have gained prominence for analyzing large datasets and identifying complex patterns. Among these, autoencoders (AEs), a specialized class of ANNs, are well-suited for unsupervised learning tasks, enabling dimensionality reduction and feature extraction. This study employs transmissibility functions (TFs) as training samples for the AE. TFs are directly derived from response measurements without the need to measure input and exhibit local sensitivity to changes in dynamic properties, making them an efficient feature for structural assessment. The reconstruction errors in TFs, quantifying the deviation between the original and AE-reconstructed data, are leveraged as damage-sensitive features for classification using a one-class support vector machine (OC-SVM). The proposed methodology is validated through numerical simulations with noise-contaminated data representing various damage scenarios in a shear-building model, as well as experimental tests on a masonry arch bridge model subjected to progressive damage. Numerical investigations demonstrate improved detection accuracy and robustness of the procedure through the incorporation of nonlinear encoding into the dimensionality reduction process, compared to the classical principal component analysis method.. Experimental results confirm the framework’s effectiveness in detecting and localizing damage using unlabeled field data. Full article

Microplastic pollution in the environment has greatly increased due to the widespread use of plastics. Antibiotics and microplastic are common contaminants, especially in aquaculture. Microplastics could act as antibiotic vectors that raise the potential of their ecotoxicological effects. In this work, we conducted several analyses of biomarker responses to examine the developmental toxicity and toxicological endpoints that polyethylene microplastics (PE-MPs) and tetracycline antibiotics (TC) induced in zebrafish (Danio rerio) embryos/larvae. The results suggested that TC-PE-MPs induced significant physiological perturbations, including attenuated spontaneous cardiac contractions, cardiotoxicity, a dose-dependent elevation in mortality, and a marked reduction in body length, accompanied by morphological alterations. The mechanistic analysis revealed that ROS accumulation triggered enzymatic activity changes, which further induced aberrant vascular development, robust inflammatory responses, and dysregulated gene expression. These findings demonstrate that PE coexistence potentiates TC’s toxicological effects, with combined exposure inducing developmental toxicity during critical organogenesis stages in zebrafish. Overall, the current research demonstrated the detrimental effects of TC-PE-MPs on early fish development, suggesting potential environmental risks. Full article

Accurate and robust information on land cover changes in urban and coastal areas is essential for effective urban land management, ecosystem monitoring, and urban planning. This paper details the methodology and results of a pixel-level classification and change detection analysis, leveraging 1945 Royal Air Force (RAF) aerial imagery and 2011 Very High-Resolution (VHR) multispectral WorldView-2 satellite imagery from the broader area of Patras, Greece. Our attention is mainly focused on the changes in the coastline from the city of Patras to the northeast direction and the two major rivers, Charadros and Selemnos. The methodology involves preprocessing steps such as registration, denoising, and resolution adjustments to ensure computational feasibility for both coastal and riverbed change detection procedures while maintaining critical spatial features. For change detection at coastal areas over time, the Normalized Difference Water Index (NDWI) was applied to the new imagery to mask out the sea from the coastline and manually archive imagery from 1945. To determine the differences in the coastline between 1945 and 2011, we perform image differencing by subtracting the 1945 image from the 2011 image. This highlights the areas where changes have occurred over time. To conduct riverbed change detection, feature extraction using the Gray-Level Co-occurrence Matrix (GLCM) was applied to capture spatial characteristics. A Support Vector Machine (SVM) classification model was trained to distinguish river pixels from non-river pixels, enabling the identification of changes in riverbeds and achieving 92.6% and 92.5% accuracy for new and old imagery, respectively. Post-classification processing included classification maps to enhance the visualization of the detected changes. This approach highlights the potential of combining historical and modern imagery with supervised machine learning methods to effectively assess coastal erosion and riverbed alterations. Full article