Search Results (21,317)

Investigating the optimal planting strategies for brassica vegetables under variable climatic conditions is essential for developing sustainable production systems in northern agricultural regions. However, comprehensive knowledge about how planting timing modulates growth, physiological responses, and yield parameters across different cultivars remains limited. We investigated vegetative development, root morphology, physiological efficiency, and marketable yield in six cauliflower cultivars (‘Amazing’, ‘Cheddar’, ‘Clementine’, ‘Flame Star’, ‘Snow Crown’, and ‘Vitaverde’) subjected to four planting dates (May 1, May 15, June 1, and June 15) across two growing seasons (2023–2024), followed by detailed morphological and physiological profiling. Planting date, cultivar selection, and seasonal variation significantly influenced all measured parameters (p < 0.001), with notable interaction effects observed for fresh root weight, stomatal conductance, water use efficiency, and yield components. Early planted cultivars consistently demonstrated superior performance under variable environmental conditions, maintaining higher growth rates, enhanced root development, and improved physiological efficiency, particularly ‘Flame Star’, ‘Snow Crown’, and ‘Cheddar’, compared to late-planted treatments. Recovery of optimal plant development was most pronounced at May planting dates, with early-established crops showing better maintenance of vegetative growth patterns and enhanced yield potential, including higher curd weights (585.7 g for ‘Flame Star’) and superior marketable grades. Morphological profiling revealed distinct clustering patterns, with early-planted cultivars forming separate groups characterized by elevated root biomass, enhanced physiological parameters, and superior yield characteristics. In contrast, late-planted crops showed reduced performance, indicative of environmental stress responses. We conclude that strategic early planting significantly enhances cauliflower production resilience through comprehensive optimization of growth, physiological, and yield parameters, particularly under May establishment conditions. The differential performance responses between planting dates provide insights for timing-based management strategies, while the quantitative morphological and physiological profiles offer valuable parameters for assessing crop adaptation and commercial viability potential under variable climatic scenarios in northern agricultural systems. Full article

We compared oxidative markers and their links to inflammation in diabetic nephropathy and hemodialysis to identify independent determinants. We studied 180 adults, 90 patients with type 2 diabetes and diabetic nephropathy and 90 patients on hemodialysis. We measured serum advanced oxidation protein products (AOPP) and thiobarbituric acid reactive substances (TBARS) by enzyme-linked immunosorbent assay (ELISA). Partial correlations were adjusted for age, sex, and albumin with false discovery rate (FDR) control. Principal component analysis (PCA) summarized inflammatory indices and linear models tested predictors of AOPP and TBARS. Oxidative damage was higher in hemodialysis, with AOPP median 25.80 versus 5.06 and TBARS 8.49 versus 1.89, p less than 0.0001. C reactive protein (CRP) and mean corpuscular volume-to-lymphocyte ratio (MCVL) were higher in patients ongoing hemodialysis; systemic immune-inflammation index (SII) was higher in diabetic nephropathy. PCA yielded a dominant inflammation axis in both cohorts, 74.73 percent in hemodialysis and 85.20 percent in diabetic nephropathy. In regression, creatinine (β = 2.47, p = 0.026) predicted AOPP in hemodialysis. Dialysis vintage inversely predicted TBARS, beta minus 0.2305, p = 0.0209. In diabetic nephropathy, the PCA inflammation score predicted AOPP, β = 1.134, p = 0.0003. Protein oxidation tracked systemic inflammation in diabetic nephropathy, but not in hemodialysis. AOPP outperformed TBARS as an inflammatory partner and a practical monitoring candidate in diabetic kidney disease. Prospective studies should test for prognostic value and therapy sensitivity. Full article

This study examines the integration of digital fabrication technologies into the design and production of mycelium-based components, addressing the growing demand for sustainable and innovative interior design solutions. Using a parametric design approach, modular and customized suspended ceiling elements were developed for a specific interior setting to explore a material-specific design approach for mycelium-based components. Three-dimensional printing was employed to produce molds, which were subsequently tested with plaster, silicone, and mycelium across three different scales. Experimental observations focused on the overall form, surface details, growth behavior and dimensional accuracy, systematically capturing volumetric deviations arising from the living nature of the material. In parallel, acoustic performance was evaluated through simulations using the Sabine method. The untreated condition demonstrated the longest reverberation times, whereas conventional panels achieved reductions consistent with typical comfort standards. Prototypes produced with mycelium yielded measurable decreases in reverberation time compared to the untreated condition, particularly within the speech frequency range, and approached the performance of standard acoustic panels. These findings suggest that mycelium-based components, when further optimized in terms of density and geometry, hold the potential to contribute both aesthetic and acoustic value within sustainable interior environments. Full article

This study presents a concise analytical framework that combines suprametric spaces with directed graph structures to model dynamic market environments. The proposed setting captures hierarchical and asymmetric relations between economic components, providing a more flexible structure than conventional metric frameworks. Within this framework, several types of contractive mappings, such as supra-Kannan, supra-Reich, and supra-Ciric contractions, are defined, and corresponding fixed point theorems are established. The theoretical results are applied to a nonlinear integral equation describing the evolution of prices in production and consumption processes. Under appropriate assumptions, the existence and uniqueness of solutions are guaranteed, and a numerical example demonstrates the convergence and practical importance of the proposed model. Full article

Biocatalysis is fundamental to biological processes and sustainable chemical productions. Over time, the biocatalysis strategy has been widely researched. Initially, biomanufacturing and catalysis of high-value chemicals were carried out through direct immobilization and application of biocatalysts, including natural enzymes and living cells. With the evolution of green chemistry and environmental concern, hybrid photoelectro-biocatalysis (HPEB) platforms are seen as a new approach to enhance biocatalysis. This strategy greatly expands the domain of natural biocatalysis, especially for bio-based components. The selective valorization of renewable furan derivatives, such as 5-hydroxymethylfurfural (HMF) and furfural, is central to advancing biomass-based chemical production. Biocatalysis offers high chemo-, regio-, and stereo-selectivity under mild conditions compared with traditional chemical catalysis, yet it is often constrained by the costly and inefficient regeneration of redox cofactors like NAD(P)H. Photoelectrocatalysis provides a sustainable means to supply reducing equivalents using solar or electrical energy. In recent years, hybrid systems that integrate biocatalysis with photoelectrocatalysis have emerged as a promising strategy to overcome this limitation. This review focuses on recent advances in such systems, where photoelectrochemical platforms enable in situ cofactor regeneration to drive enzymatic transformations of furan-based substrates. We critically analyze representative coupling strategies, materials and device configurations, and reaction engineering approaches. Finally, we outline future directions for developing efficient, robust, and industrially viable hybrid catalytic platforms for green biomass valorization. Full article

Recent advances in molding technology have enabled the fabrication of plastic molded components with complex geometries. In contact lens (CL) manufacturing, a double-sided molding process using resin molds is employed, in which the front and back surfaces of the lens are replicated through injection molding. However, thermal deformation during polymerization can alter the mold shape, thereby affecting the optical characteristics of the final lenses. This study proposes a high-precision optical evaluation method for resin molds used in contact lens (CL) manufacturing, utilizing a reflective wavefront sensor and optical coherence tomography (OCT). The wavefront sensor demonstrated high measurement accuracy (≈1/100λ) and reproducibility (≈1/200λ) as confirmed using reference samples, and yielded values of approximately 0.012–0.015 μm for the resin molds. Five mold designs with radii of curvature ranging from 6.500 to 8.500 mm were evaluated, revealing that Zernike coefficients varied depending on design and thermal treatment conditions. In particular, astigmatism (Z04) and coma aberrations (Z07) exhibited pronounced trends. A strong correlation was also observed between the Zernike coefficient Z07 and the mold thickness asymmetry measured by OCT. When the thickness difference increased by 2.3 times due to thermal treatment, Z07 increased to 1.9 times. In contrast, Z04 showed no consistent trend and exhibited significant variability (standard deviation > 0.5 μm) after polymerization. The proposed method enables precise detection of subtle shape variations and aberrations, providing valuable feedback for optimizing molding conditions and improving the quality of contact lens production. Furthermore, this method can also be applied to the quality evaluation of other optical components. Full article

At present, ionic liquids (ILs) are increasingly being used to extract natural products as green solvents, but their residues can lead to risks in terms of further use for the extracted herbal materials. Therefore, it is necessary to remove them with simple and effective methods. For example, after the toxic anthraquinones in Polygonum multiflorum are removed by extraction with the IL of [C₄Bim][PTSA], it needs to be recovered and reused, and the useful stilbene glycosides should not suffer from obvious loss as they are the main functional components. In this study, an ultrasonic method with n-propanol was used to remove the residual [C₄Bim][PTSA] in the solid powders of Polygonum multiflorum that had been extracted for anthraquinones. After single-factor optimization, the removal conditions were as follows: the removal temperature was 303.15 K, the solid–liquid ratio was 1:200 (w (1 g):v (200 mL)), the ultrasonic time was 40 min, and there were four operations. Under these conditions, ILs could be completely removed with almost no loss of stilbene glycosides in solid powders. After that, the IL in the extracting solution and scrubbing solution was recovered by the back-extraction method, and an IL with high purity could be obtained for reuse. The total recovery efficiency of the IL reached more than 98%. Then gas chromatography (GC) was conducted for the determination of residual ethanol and n-propanol in the solid powders of Polygonum multiflorum, which could be used to quickly detect the contents of two organic solvents within three minutes. Besides that, the method could also be applied to the determination of residual organic solvents in the raw materials of Polygonum multiflorum, and the results showed that the residue of ethanol and n-propanol in the solid powders were in accordance with the general provisions of the current Chinese Pharmacopoeia. According to the developed procedures and optimized conditions, the recovered IL could be reused in five runs at least. General applicability and greenness assessment for the developed process also proved that it is an ideal method, which has potential in large-scale application. Full article

Background: The use of baobab seed beverages as coffee alternatives represents a novel approach to upcycling by-products. Baobab seed aqueous extract is caffeine-free and contains numerous compounds of nutritional interest. The composition and sensory characteristics of baobab seed beverage can be modulated by roasting and brewing conditions. Objective: This study aimed to assess the effect of using different fluidised bed roasting temperatures and microwave infusion on the nutritional and functional properties of the beverage. Results: Higher roasting temperatures increased solubility, melanoidin content, pH, titratable acidity, colour, phenolic content, and antioxidant activity, while the concentration of chlorogenic acid and caffeic acid decreased. Upon microwave infusion, antioxidant activity, phenolic content (gallic acid, coumaric acid, caffeic acid, and vanillic acid), protein content, and soluble fibre content increased. Chlorogenic acid was not present in microwave-infused samples, and the amount of caffeic acid decreased. The fat content remained similar across all samples. The major volatile components identified in the roasted seeds were furans and pyrazines. Conclusions: These findings highlight the potential of baobab seed beverages as coffee alternatives and the impact of roasting and brewing conditions on their nutritional and functional properties. Full article

A two-year (2023–2024) multifactorial field study was conducted under the agro-climatic conditions of Northern Kazakhstan, with the objective of refining cultivation practices for hayfields of perennial legumes and grasses, including alfalfa (Medicago sativa L.), smooth brome (Bromus inermis Leyss.), and sainfoin (Onobrychis arenaria Kit). The elements targeted for optimization included the species composition and component ratios in the mixtures, as well as the regimes of pre-sowing and foliar applications of growth regulators (AminoMax, Black Jak, Miller Start, Lider-S). The integrated experimental design accounted for laboratory and field germination, biometric parameters (plant height, leafiness), phenophase dynamics, autumn survival and overwintering, indicators of photosynthetic activity, as well as yields of green biomass and dry matter, and chemical composition (crude protein, fiber, ash, fat, and nitrogen-free extract). Grass–legume mixtures ensured more stable progression of phenophases, improved overwintering, and enhanced protein value compared to monocultures; the inclusion of sainfoin contributed to improved forage quality without compromising yield. Growth regulators promoted accelerated initial plant development and enhanced the intensity of net photosynthetic productivity. The greatest effect of application was observed in the grass component with Miller Start, whereas in the legume species it was most pronounced with AminoMax. The results of the study revealed that the optimal proportion of legumes in the forage mixtures is 30–40%. Under contrasting hydrothermal conditions, the yield of fresh and dry matter ranged from 4.19 to 4.81 t ha⁻¹ and 1.27–1.51 t ha⁻¹ (2023) to 10.43–14.46 t ha⁻¹ and 3.05–4.63 t ha⁻¹ (2024). The greatest effect was observed with Miller Start and AminoMax treatments (p < 0.05), whereas the action of Black Jak and Lider-S was moderate, confirming differences in their mechanisms of action under contrasting weather conditions. Full article

The component composition of Bulgarian essential oil from Origanum heracleoticum L. was determined by gas chromatography and mass spectrometry analysis. Fifty-three different compounds were identified in the essential oil, with carvacrol (70.31–70.52%) and p-cymene (10.86–11.03%) determined to be the main components. The antimicrobial activity of the essential oil was determined against 138 clinical isolates of four species of Candida spp., and it was found to exhibit high antimycotic activity (minimal inhibitory concentration (MIC) between 64 μg mL⁻¹ and 128 μg mL⁻¹) against both fluconazole-sensitive and fluconazole-resistant strains. It was found that Bulgarian essential oil from O. heracleoticum L. disrupts the normal permeability of the cell membrane and inhibits some of the main virulence factors of medically important fungi in the genus Candida by preventing germination, transition to the filamentous stage of growth and the production of hydrolytic enzymes. Full article

We investigate the three-dimensional incompressible fractional Navier–Stokes system with directional fractional diffusion: a vertical dissipative operator of order $2\alpha \in (0,2]$ acting on the full velocity field together with a horizontal fractional operator of order $2\beta \in (0,2]$ applied to the vertical average of one horizontal component. This anisotropic, nonlocal structure captures media in which smoothing acts with unequal strength by direction. For small, divergence-free initial data in an anisotropic energy class, we establish global well-posedness and stability of the zero state, including uniqueness and continuous dependence on the data. The analysis crucially relies on an average oscillation decomposition in the vertical variable, a fractional Poincaré inequality aligned with the vertical direction, and sharp product/commutator bounds compatible with the anisotropic splitting. We provide explicit estimates for direction-dependent smoothing and algebraic decay governed by $(\alpha ,\beta )$, and we show that the conclusions persist under small perturbation of the dissipation parameters. Full article

Demand-Driven Material Requirements Planning (DDMRP) has been proposed as a solution for managing uncertainty and variability in supply chains by combining decoupling, buffer management and demand-driven planning principles. A key element of DDMRP is its inventory replenishment model, which relies on dynamically adjusted inventory buffers rather than fixed stock levels. However, parameterization of these buffers often involves subjective choices, raising concerns about consistency and performance. This paper assesses the DDMRP replenishment model through discrete-event simulation of a multi-echelon, capacity-constrained production system. Two alternative formulations of the safety stock term in the red zone are compared: the original factor-based approach and a revised formula that incorporates measurable variability coefficients. While both safety stock formulations yield similar numerical results, the revised formula enhances transparency and reduces subjectivity. Assessing the impact of introducing a buffer for components in addition to a finished goods buffer further shows that the components buffer can reduce finished goods inventory requirements while maintaining service levels. These findings contribute to a better understanding of the DDMRP replenishment model, offering practical insights for parameter selection and supply chain design. Full article

The increased production of sewage sludge is a major environmental concern as the sludge contains hazardous components, particularly human bacterial pathogens (HBPs). Transit of sewage sludge through the earthworm gut reduce or even eliminate HBPs and modify bacterial taxonomic and functional composition. However, it is unclear whether the effect is general or dependent on the type of sewage sludge involved. We characterized the taxonomic and functional profiles of bacterial assemblages in sewage sludge from different wastewater treatment plants (WWTPs), before (sludge) and after earthworm gut transit (casts). We found that composition and diversity of both taxonomic and functional bacterial communities of sludge and casts were significantly different. However, these differences varied among WWTPs with both increases and decreases in composition and diversity after gut transit. Interestingly, most bacterial taxa present in earthworm casts were not detected in the original sewage sludge. All sludge samples initially contained low levels of HBPs, which were significantly reduced or eliminated in earthworm casts. Nevertheless, gut transit increased the abundance of some HBPs. Further studies should determine whether vermicomposting effectively eliminates these HBPs and whether the differences in earthworm cast bacterial communities, which are dependent on the sewage sludge source, persist in the final vermicompost. Full article

The development of cosmetic prostheses benefits significantly from the integration of additive manufacturing technologies, which offer new possibilities for personalization, rapid production, and cost efficiency. This study explores the potential of selected additive manufacturing methods for fabricating prosthetic fingers used in upper limb cosmetic prostheses. Esthetic and mechanical properties of the printed components were assessed alongside production efficiency and material use. Quantitatively, maximum bending loads ranged from 9 to 136 N, maximum compressive loads from 12 to 158 N, and sample mass from 4 to 22 g across configurations. The findings confirm that additive manufacturing enables the creation of prosthetic components that meet basic cosmetic and functional expectations. However, the choice of manufacturing method strongly influences surface quality, structural performance, production time, and economic feasibility. These results highlight the importance of matching technological capabilities with specific clinical and design requirements. The study contributes to the ongoing development of digital fabrication workflows for prosthetics and underscores the need for standardized evaluation criteria to support reliable comparisons across materials and manufacturing processes. Full article

In this study, thermogravimetric analysis (TGA) was coupled with Fourier-transform infrared (FTIR) spectroscopy to systematically investigate the pyrolysis characteristics and mechanisms of cement fiberboard across varying heating rates. Experimental findings demonstrated that the thermal degradation process occurs in four distinct phases. Overlapping decomposition peaks in DTG curves were successfully resolved using a double-Gaussian deconvolution algorithm. A comprehensive kinetic analysis was conducted by integrating model-free iso-conversional methods (Flynn–Wall–Ozawa and Kissinger–Akahira–Sunose analysis) with a model-fitting technique (Coats–Redfern approximation) to determine the activation energies for each degradation stage. A subsequent FTIR spectroscopic analysis revealed that the evolution of gaseous products follows the sequence CO₂ > H₂O > CH₄. The CO₂ release was found to originate from multiple pathways, including the decomposition of organic components and high-temperature inorganic reactions. Notably, while the heating rate had a negligible impact on product speciation, it exhibited a statistically significant influence on CO₂ emission intensities. Finally, mechanistic interpretations integrating Arrhenius parameters with time-resolved infrared spectral features were proposed for each thermal decomposition stage. Full article