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4 Results Found

  • Article
  • Open Access
6 Citations
2,653 Views
19 Pages

Median Nerve Stimulation for Treatment of Tics: A 4-Week Open Trial with Ecological Momentary Assessment

  • Ann M. Iverson,
  • Amanda L. Arbuckle,
  • David Y. Song,
  • Emily C. Bihun and
  • Kevin J. Black

28 March 2023

Median nerve stimulation (MNS) at 10–12 Hz was recently proposed as a treatment for Tourette syndrome and other chronic tic disorders (TS/CTD). We report on 31 participants ages 15–64 with TS/CTD in an open-label, comparative (within-grou...

  • Article
  • Open Access
2 Citations
2,995 Views
23 Pages

The Pathophysiology of Gilles de la Tourette Syndrome: Changes in Saccade Performance by Low-Dose L-Dopa and Dopamine Receptor Blockers

  • Yasuo Terao,
  • Yoshiko Nomura,
  • Hideki Fukuda,
  • Okihide Hikosaka,
  • Kazue Kimura,
  • Shun-ichi Matsuda,
  • Akihiro Yugeta,
  • Francesco Fisicaro,
  • Kyoko Hoshino and
  • Yoshikazu Ugawa

25 November 2023

Aim: To elucidate the pathophysiology of Gilles de la Tourette syndrome (GTS), which is associated with prior use of dopamine receptor antagonists (blockers) and treatment by L-Dopa, through saccade performance. Method: In 226 male GTS patients (5&nd...

  • Review
  • Open Access
35 Citations
7,364 Views
12 Pages

Background. Tourette syndrome (TS) is a childhood-onset neuropsychiatric disorder consisting of impairing motor and vocal tics which often persists adolescent and adult years. In this older refractory group, standard treatments such as pharmacotherap...

  • Review
  • Open Access
29 Citations
8,621 Views
19 Pages

The Use of Deep Brain Stimulation in Tourette Syndrome

  • Ladan Akbarian-Tefaghi,
  • Ludvic Zrinzo and
  • Thomas Foltynie

Tourette syndrome (TS) is a childhood neurobehavioural disorder, characterised by the presence of motor and vocal tics, typically starting in childhood but persisting in around 20% of patients into adulthood. In those patients who do not respond to p...