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  • Review
  • Open Access
7 Citations
5,932 Views
11 Pages

Etiology and Treatment of Peri-Implant Soft Tissue Dehiscences: A Narrative Review

  • Charalampos Kaddas,
  • Eirini Papamanoli and
  • Yiorgos A. Bobetsis

16 May 2022

Implant soft tissue dehiscences compromise not only the aesthetics of the supported restorations but implant survival in the long run. The aim of this narrative review was to briefly present the causative factors of buccal peri-implant soft tissue de...

  • Review
  • Open Access
6 Citations
7,435 Views
15 Pages

Peri-Implant Soft Tissue Augmentation with Connective Tissue Graft Substitutes

  • Ilham Mounssif,
  • Valentina Bentivogli,
  • Alexandra Rendón,
  • Claudio Mazzotti and ,
  • Isabella De Rubertis,
  • Giovanni Zucchelli and
  • Martina Stefanini
  • + 2 authors+ 0 author

18 September 2025

The soft tissue around dental implants plays a crucial role in achieving successful rehabilitation outcomes related to aesthetics, peri-implant health, and bone stability. These tissues, made up of mucosa and keratinized tissue, serve different funct...

(This article belongs to the Section Applied Biosciences and Bioengineering)
  • Conference Report
  • Open Access
46 Citations
7,452 Views
9 Pages

Peri-implant Soft Tissue Management: Cairo Opinion Consensus Conference

  • Fernando Suárez López Del Amo,
  • Shan-Huey Yu,
  • Gilberto Sammartino,
  • Anton Sculean and ,
  • Giovanni Zucchelli,
  • Giulio Rasperini,
  • Pietro Felice,
  • Giorgio Pagni,
  • Vincenzo Iorio-Siciliano and
  • Hom-Lay Wang
  • + 28 authors+ 23 authors

Peri-implant soft tissues play a role of paramount importance, not only on the esthetic appearance, but also on the maintenance and long-term stability of implants. The present report presents the conclusions from the Consensus Conference of the Sout...

(This article belongs to the Collection Modern Patient-Centered Dental Care)
  • Article
  • Open Access
5 Citations
6,393 Views
34 Pages

3 April 2025

Background/Objectives: The peri-implant soft tissue seal is crucial for the long-term success of subcrestally placed implants (SPIs). However, conventional biologic width—now referred to as supracrestal tissue attachment (STA)—models, ori...

(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
  • Case Report
  • Open Access
2 Citations
4,088 Views
9 Pages

Buccal Peri-Implant Soft Tissue Augmentation by Means of a Porcine Collagen Matrix: A Proof of Concept Technical Note

  • Mario Beretta,
  • Carlo Maiorana,
  • Mattia Manfredini,
  • Susanna Ferrario and
  • Pier Paolo Poli

28 December 2020

The quality and quantity of peri-implant soft tissues at the crestal portion of dental implants are important aspects to consider for a long-term successful implant-supported rehabilitation. Some relevant factors attributed to the implant health incl...

(This article belongs to the Special Issue Tissue Regeneration in Dentistry: From Biomaterials to Stem Cell Therapy)
  • Article
  • Open Access
1 Citations
519 Views
17 Pages

Baseline-Dependent Biological Response to Peri-Implant Soft Tissue Augmentation: A Secondary Analysis of a Randomized Clinical Trial

  • Jakub Hadzik,
  • Paweł Kubasiewicz-Ross,
  • Umberto Romeo,
  • Krzysztof Kujawa and ,
  • Nicola Alberto Valente and
  • Marzena Dominiak
  • + 1 author+ 0 author

1 September 2026

Objectives: Clinical outcomes of peri-implant soft tissue augmentation remain variable, and baseline-associated factors of treatment response are poorly understood. This exploratory study aimed to evaluate baseline-associated patterns of peri-implant...

(This article belongs to the Special Issue Functional Natural, Hybrid and Bioinspired Biomaterials for Biomedical Applications)
  • Article
  • Open Access
4 Citations
876 Views
14 Pages

Methodological Validation of the PIROP Ultrasound-Based System for Measuring Peri-Implant Soft Tissue Thickness in a Clinical Setting

  • Jakub Hadzik,
  • Paweł Kubasiewicz-Ross,
  • Krzysztof Kujawa,
  • Tomasz Gedrange and
  • Marzena Dominiak

17 February 2026

Background/Objectives: Accurate and reproducible assessment of peri-implant soft tissue thickness is an important methodological aspect of contemporary implant dentistry, particularly in longitudinal studies evaluating soft tissue dimensions. While u...

(This article belongs to the Special Issue Clinical Updates on Prosthodontics)
  • Review
  • Open Access
612 Views
30 Pages

Dual-Function Antimicrobial Peptides as a Prospective Strategy Against Peri-Implantitis: Bridging Cutaneous Wound Healing and the Peri-Implant Soft-Tissue Seal

  • Laura Maghiar,
  • Andrada Iftode,
  • Andreea-Adriana Neamțu,
  • Teodor-Andrei Maghiar and ,
  • Andreea Maria Cristea,
  • Cristina Dumitrescu,
  • Alina Anton,
  • Andreea-Mihaela Kis,
  • Valentin-Cristian Iovin and
  • Andrei Paul Tent
  • + 10 authors+ 5 authors

28 July 2026

Peri-implantitis, a biofilm-driven inflammatory disease that causes progressive loss of the bone supporting dental implants, is common and difficult to treat: mechanical debridement cannot fully decontaminate the implant surface, and antibiotic adjun...

(This article belongs to the Special Issue Advances in Oral Diseases and Oral Implantology)
  • Review
  • Open Access
11 Citations
7,508 Views
25 Pages

Peri-Implant Soft Tissue in Contact with Zirconium/Titanium Abutments from Histological and Biological Perspectives: A Concise Review

  • Fatma A. N. Abouel Maaty,
  • Mai A. Ragab,
  • Yasmin M. El-Ghazawy,
  • Fatma I. Elfaiedi and ,
  • Marwa M. S. Abbass,
  • Israa Ahmed Radwan,
  • Dina Rady,
  • Sara El Moshy,
  • Nahed Sedky Korany and
  • Karim M. Fawzy El-Sayed
  • + 7 authors+ 2 authors

17 January 2025

Dental implants are crucial in contemporary oral rehabilitation, necessitating optimal integration with the surrounding soft tissues for durable success. The attachment between the implant surface and peri-implant mucosa should establish a secure sea...

(This article belongs to the Special Issue Recent Advances in Regenerative Dentistry—Second Edition)
  • Review
  • Open Access
354 Views
23 Pages

3 August 2026

Advanced dental implant systems are clinically successful when their material properties, surface topography, abutment geometry and implant–abutment connection design support both mechanical stability and biological integration. In Morse-tapere...

(This article belongs to the Special Issue Advanced Dental Materials: From Design to Application, Third Edition)
  • Brief Report
  • Open Access
1 Citations
1,008 Views
11 Pages

Horizontal Platelet-Rich Fibrin Membrane Block for Peri-Implant Soft Tissue Augmentation: An Experimental Animal Study with Clinical Illustration

  • Hao Zeng,
  • Yan Wei,
  • Shimin Yu,
  • Xiaoxin Zhang and ,
  • Yun Qiu,
  • Richard J. Miron,
  • Yulan Wang and
  • Yufeng Zhang
  • + 3 authors+ 0 author

4 March 2026

Background/Objectives: Adequate peri-implant soft tissue thickness is essential for long-term peri-implant health and esthetics. Horizontal platelet-rich fibrin (H-PRF) has been proposed to support soft tissue regeneration; however, experimental and...

(This article belongs to the Section Dental Implantology)
  • Review
  • Open Access
378 Views
69 Pages

17 September 2026

Soft tissue deficiencies around teeth and dental implants remain a significant challenge in contemporary periodontology and implant dentistry. These deficiencies influence a number of factors, including esthetic outcomes, peri-implant tissue stabilit...

(This article belongs to the Special Issue New Progress in the Polymer-Based Biomaterials)
  • Review
  • Open Access
1,180 Views
21 Pages

Anodized Titanium Implant Abutments: Effects on Surface Properties, Peri-Implant Soft Tissue Esthetics, and Biological Outcomes—A Focused Narrative Review

  • Elana Y. Laks,
  • Amal Al-Faraj,
  • Chao-Chieh Yang,
  • Michele L. Kirkup and ,
  • John A. Levon and
  • Wei-Shao Lin
  • + 1 author+ 0 author

3 July 2026

Background/Objectives: To summarize evidence on whether anodization of titanium implant abutments modifies abutment surface/physical properties, peri-implant soft tissue esthetics, and biological outcomes compared with machined titanium and alternati...

(This article belongs to the Special Issue Feature Review Papers in Dentistry: 2nd Edition)
  • Article
  • Open Access
256 Views
11 Pages

Use of Demineralized Autologous Dentin Graft with the Tooth Processing Device in Immediate Post-Extraction Implant Placement and Loading: A 12-Month Evaluation of Peri-Implant Soft Tissue Stability

  • Giuseppe Bavetta,
  • Stefano Di Carlo,
  • Giulia Amelina,
  • Francesca De Angelis and ,
  • Luca Piccoli,
  • Nicola Pranno,
  • Enrico Guerrieri and
  • Edoardo Brauner
  • + 3 authors+ 0 author

13 October 2026

Purpose: To evaluate the effectiveness of immediate implant placement and loading combined with autologous dentin grafting in reducing post-extraction tissue remodelling, with particular emphasis on peri-implant soft tissue stability in the esthetic...

(This article belongs to the Special Issue Dental Biomaterials: Research, Development and Applications)
  • Article
  • Open Access
7 Citations
4,176 Views
17 Pages

10 September 2024

The mucosa height has always been of interest in modern implant dentistry to obtain biomimetic results. Papilla height, mucosa scalloping, and free mucosal margin level are crucial to achieve “pink aesthetics”. The aim of this study was t...

(This article belongs to the Special Issue Medical Application of Functional Biomaterials (2nd Edition))
  • Article
  • Open Access
9 Citations
3,857 Views
16 Pages

Electron Microscopy (EM) Analysis of Collagen Fibers in the Peri-Implant Soft Tissues around Two Different Abutments

  • Ugo Covani,
  • Enrica Giammarinaro,
  • Natalia Di Pietro,
  • Simona Boncompagni and ,
  • Giorgia Rastelli,
  • Tea Romasco,
  • Eugenio Velasco-Ortega,
  • Alvaro Jimenez-Guerra,
  • Giovanna Iezzi and
  • Simone Marconcini
  • + 6 authors+ 1 author

The design of the implant prosthesis–abutment complex appears crucial for shaping healthy and stable peri-implant soft tissues. The aim of the present animal study was to compare two implants with different healing abutment geometries: a concav...

(This article belongs to the Special Issue New Trends in Biomaterials and Implants for Dentistry)
  • Review
  • Open Access
8 Citations
7,226 Views
12 Pages

Impact of Metformin on Periodontal and Peri-Implant Soft and Hard Tissue

  • Faisal E. Aljofi,
  • Aminah Alesawy,
  • Bader Alzaben,
  • Marwa Alshaikh and ,
  • Norah Alotaibi,
  • Hajer A. Aldulaijan,
  • Sami Alshehri,
  • Eman Aljoghaiman,
  • Yousif A. Al-Dulaijan and
  • Mishali AlSharief
  • + 5 authors+ 0 author

Periodontal and peri-implant soft and hard tissue in diabetic patients have always been a topic of interest for researchers and clinicians alike. Among which, a subtopic that has attracted more attention is the beneficial effect of metformin (MF) on...

(This article belongs to the Section Global Health)
  • Article
  • Open Access
3 Citations
3,612 Views
14 Pages

The Trouser Technique: A Novel Approach for Peri-Implant Soft Tissue Augmentation

  • Pablo Pavón,
  • Carla Fons-Badal,
  • Natalia Pérez-Rostoll,
  • Jorge Alonso-Pérez-Barquero and ,
  • María Fernanda Solá-Ruiz and
  • Rubén Agustín-Panadero
  • + 1 author+ 0 author

14 July 2025

Background/Objectives: Peri-implant mucosa plays a key role in both peri-implant health and aesthetics. Differences in contour and color between implants and natural teeth can negatively affect patient satisfaction, while soft tissue deficiency may l...

(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
  • Article
  • Open Access
979 Views
14 Pages

Surgical Correction of Keratinized Mucosa Deficiency Around Dental Implants: A Clinical, Histological and Immunohistochemical Study

  • Emil K. Khabirov,
  • Gulshat T. Saleeva,
  • Dmitry E. Tsyplakov,
  • Rinat A. Saleev and
  • Laysan R. Shakirova

28 April 2026

Background/Objectives: Peri-implant inflammatory complications remain a major cause of late implant failure and are closely associated with the condition of peri-implant soft tissues. Insufficient keratinized attached mucosa has been identified as a...

(This article belongs to the Special Issue Risk Factors in Implantology)
  • Article
  • Open Access
11 Citations
3,942 Views
13 Pages

Behaviour of the Peri-Implant Soft Tissue with Different Rehabilitation Materials on Implants

  • María Baus-Domínguez,
  • Serafín Maza-Solano,
  • Celia Vázquez-Pachón,
  • Marta Flores-Cerero and ,
  • Daniel Torres-Lagares,
  • María-Ángeles Serrera-Figallo and
  • Laura Macías-García
  • + 2 authors+ 0 author

7 August 2023

(1) Background: Mucointegration seems to gain interest when talking about success in the maintenance of dental implants. As we well know, collagen fibres cannot be inserted due to the lack of root structure on the implant surface, so the structural i...

(This article belongs to the Special Issue Advances in Polymeric Dental Materials)
  • Article
  • Open Access
6 Citations
2,009 Views
15 Pages

3 August 2023

The present pilot study was designed by hypothesizing a possible correlation between lack of accuracy in implant placement and peri-implant hard and soft tissue health. A total of five patients underwent computer-guided implant surgery and full-arch...

(This article belongs to the Special Issue Current Trends and Future Directions in Prosthetic and Implant Dentistry in the Digital Era, 2nd Edition)
  • Case Report
  • Open Access
1 Citations
577 Views
14 Pages

The “B.U.M.P.” Concept: Combined Prosthetic and Surgical Approach in Esthetic Immediate Implant Placement. A Case Report

  • Giacomo Dallari,
  • Valentina Bentivogli,
  • Jonathan Esquivel,
  • Matteo Sangiorgi and ,
  • Ilham Mounssif,
  • Lorenzo Breschi,
  • Giovanni Zucchelli and
  • Martina Stefanini
  • + 3 authors+ 0 author

Background/Objectives: Immediate implant placement in the esthetic zone is increasingly preferred due to its advantages for patient comfort and reduced treatment time. However, maintaining peri-implant soft tissue volume and preserving or reconstruct...

(This article belongs to the Special Issue Contemporary Treatment and Management of Periodontal and Peri-Implant Diseases and Conditions)
  • Review
  • Open Access
19 Citations
7,879 Views
15 Pages

Soft Tissue Substitutes in Periodontal and Peri-Implant Soft Tissue Augmentation: A Systematic Review

  • Roberto Rotundo,
  • Gian Luca Pancrazi,
  • Alessia Grassi,
  • Lara Ceresoli and ,
  • Giovanna Laura Di Domenico and
  • Vanessa Bonafede
  • + 1 author+ 0 author

6 March 2024

Background: Different extracellular matrix (ECM)-based technologies in periodontal and peri-implant soft tissue augmentation have been proposed in the market. The present review compared the efficacy of soft tissue substitutes (STSs) and autogenous f...

(This article belongs to the Section Biomaterials)
  • Article
  • Open Access
22 Citations
4,314 Views
16 Pages

The presence of epithelial and connective tissue attachment at the peri-implant–soft tissue region has been demonstrated to provide a biological barrier of the alveolar bone from the oral environment. This barrier can be improved via surface mo...

(This article belongs to the Special Issue Bioengineered In Vitro Models for Biomedical Applications)
  • Review
  • Open Access
1,179 Views
15 Pages

Osteo-Inductive Strategies for Enhancing Osseointegration and Optimizing Peri-Implant Emergence Profile: A Narrative Review

  • Ioan Sirbu,
  • Elisei Adelin Radu,
  • Andy Radu Leibovici,
  • Andreea Mihaela Custura and ,
  • Ruxandra Stanescu,
  • Alexandra Tuta,
  • Vladimir Nastasie and
  • Valentin Daniel Sirbu
  • + 3 authors+ 0 author

18 May 2026

Background: Osteoinduction and bone regeneration are fundamental biological mechanisms enabling osseointegration and long-term durability of endosseous dental implants. In clinical practice, poor bone conditions, aesthetic demands, and peri-implant s...

(This article belongs to the Special Issue Oral Implantology and Bone Regeneration: 2nd Edition)
  • Article
  • Open Access
35 Citations
12,357 Views
20 Pages

2 February 2024

This study aimed to evaluate the effect of customized healing abutments compared to prefabricated healing abutments in immediate implant sites. Twelve patients requiring single immediate implant placement were divided into two groups: a prefabricated...

(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
  • Article
  • Open Access
4 Citations
5,778 Views
14 Pages

Case Report of a Dental Implant with Conometric Abutment–Prosthetic Cap Connection: Advanced High-Resolution Imaging and Peri-Implant Connective Tissue Performance

  • Nicole Riberti,
  • Emira D’Amico,
  • Tania Vanessa Pierfelice,
  • Michele Furlani and ,
  • Alessandra Giuliani,
  • Adriano Piattelli,
  • Giovanna Iezzi and
  • Luca Comuzzi
  • + 3 authors+ 0 author

27 March 2024

Background: In recent years, the use of conometric systems to connect dental implant abutments and prosthetic caps has been advocated because they seem to eliminate the side effects reported when using screw- and cement-connected prosthetic restorati...

(This article belongs to the Special Issue New Trends, Materials, and Technologies and Consolidating Best Practices in Dentistry)
  • Article
  • Open Access
27 Citations
6,105 Views
16 Pages

In Vitro Effects of Streptococcus oralis Biofilm on Peri-Implant Soft Tissue Cells

  • Alexandra Ingendoh-Tsakmakidis,
  • Jörg Eberhard,
  • Christine S. Falk,
  • Meike Stiesch and
  • Andreas Winkel

15 May 2020

Human gingival epithelial cells (HGEps) and fibroblasts (HGFs) are the main cell types in peri-implant soft tissue. HGEps are constantly exposed to bacteria, but HGFs are protected by connective tissue as long as the mucosa–implant seal is inta...

(This article belongs to the Special Issue Immunomodulatory Factors in Host Defense)
  • Case Report
  • Open Access
2 Citations
4,060 Views
15 Pages

11 November 2025

Background: Subcrestally placed implants (SPIs) present advantages for bone preservation and soft tissue support but pose challenges in maintaining peri-implant soft tissue health. This case explores the role of Crest to Restoration Distance (CRD) in...

  • Case Report
  • Open Access
638 Views
19 Pages

10 October 2026

Background: Subcrestally placed implants (SPIs) may create a soft-tissue compartment between a subcrestal implant component and the adjacent crestal bone, but the histologic characteristics of this tissue remain incompletely understood. This report e...

(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
  • Case Report
  • Open Access
3 Citations
4,767 Views
11 Pages

Peri-implant soft tissue deficiency (PSTD) is a significant factor impacting aesthetics, particularly in the anterior zone, where labial bone resorption and thin peri-implant phenotypes are common. The occurrence of a gray color around the implant fi...

(This article belongs to the Special Issue Recent Advances in Dental Implants and Oral Health)
  • Review
  • Open Access
628 Views
22 Pages

1 September 2026

Subepithelial connective tissue grafting (SCTG) is widely used to increase peri-implant mucosal thickness and buccal soft-tissue volume, but its relevance to marginal bone stability remains uncertain. This narrative review examines whether SCTG provi...

(This article belongs to the Special Issue Dental Implantology: Clinical Updates and Perspectives—2nd Edition)
  • Article
  • Open Access
3 Citations
3,398 Views
11 Pages

Background: We have recently proposed an alternative strategy of free gingival graft (FGG) and connective tissue graft (CTG) using micronized-gingival connective tissues (MGCTs). The advantage of this strategy is that MGCTs from a small piece of maxi...

  • Article
  • Open Access
19 Citations
5,912 Views
17 Pages

Immunohistochemical Results of Soft Tissues around a New Implant Healing-Abutment Surface: A Human Study

  • Barbara Ghinassi,
  • Gianmaria D’Addazio,
  • Angela Di Baldassarre,
  • Beatrice Femminella and ,
  • Giorgio Di Vincenzo,
  • Maurizio Piattelli,
  • Giulia Gaggi and
  • Bruna Sinjari
  • + 3 authors+ 0 author

2 April 2020

Although, the high success rate of implant rehabilitation treatment, the biological complications such as bone loss and peri-implantitis are still present. The creation of a coronal biological seal between the implant and the oral tissues seems to be...

(This article belongs to the Special Issue Advances in Clinical and Translational Research of Oral Surgery, Biomaterials, and Oral Disease Management)
  • Review
  • Open Access
7 Citations
4,127 Views
13 Pages

31 May 2022

Plastic peri-implant surgical procedures aiming to increase soft tissue volume around dental implants have long been well-described. These are represented by: pedicle soft tissue grafts (rotational flap procedures and advanced flap procedures) and fr...

(This article belongs to the Section Biomaterials)
  • Article
  • Open Access
14 Citations
10,361 Views
11 Pages

Association between Peri-Implant Soft Tissue Health and Different Prosthetic Emergence Angles in Esthetic Areas: Digital Evaluation after 3 Years’ Function

  • Diego Lops,
  • Eugenio Romeo,
  • Stefano Calza,
  • Antonino Palazzolo and ,
  • Lorenzo Viviani,
  • Stefano Salgarello,
  • Barbara Buffoli and
  • Magda Mensi
  • + 3 authors+ 0 author

23 October 2022

Background: The aim of the present retrospective study was to assess peri-implant soft tissue health for implants restored with different prosthetic emergence profile angles. Methods: Patients were treated with implants supporting fixed dentures and...

(This article belongs to the Special Issue Current Trends and Future Directions in Prosthetic and Implant Dentistry in the Digital Era)
  • Article
  • Open Access
478 Views
14 Pages

1 September 2026

Objectives: To evaluate the relationship between papilla fill, peri-implant esthetic outcomes, and radiographic parameters in anterior single-tooth implants, and to assess the clinical applicability of the Complex Esthetic Index (CEI). Materials and ...

  • Case Report
  • Open Access
2 Citations
2,498 Views
15 Pages

The Prosthetic Rehabilitation of Maxillary Aesthetic Area Guided by a Multidisciplinary Approach: A Case Report with Histomorphometric Evaluation

  • Stefano Speroni,
  • Luca Antonelli,
  • Luca Coccoluto,
  • Marco Giuffrè and ,
  • Alessandro Zucchelli,
  • Francesco Sarnelli,
  • Vincenzo Ronsivalle and
  • Giovanni Zucchelli
  • + 3 authors+ 0 author

Background: The rehabilitation of complex bone defects in the anterior maxilla presents significant challenges in restoring both function and esthetics. A multidisciplinary approach integrating guided bone regeneration (GBR) and connective tissue gra...

  • Article
  • Open Access
1 Citations
2,936 Views
16 Pages

A Preliminary Randomized Trial on the Efficiency and Clinical Value of a Cementless Screw-Retained Implant Workflow in Single-Implant Restorations

  • Sang-Yoon Park,
  • Sung-Woon On,
  • Tae-Yoon Park,
  • Seoung-Won Cho and ,
  • Sang-Min Yi,
  • Soo-Hwan Byun,
  • Hyun-Sook Han,
  • Lee-Kyoung Kim and
  • Byoung-Eun Yang
  • + 4 authors+ 0 author

10 October 2025

This randomized controlled clinical trial compared a conventional combined screw- and cement-retained prosthesis (CSCRP) workflow (control group) with a fully digital cementless screw-retained prosthesis (CL-SRP) system (test group) for single poster...

(This article belongs to the Special Issue Advances in Oral and Maxillofacial Implants)
  • Article
  • Open Access
17 Citations
6,022 Views
14 Pages

A Topical Desiccant Agent in Association with Manual Debridement in the Initial Treatment of Peri-Implant Mucositis: A Clinical and Microbiological Pilot Study

  • Giorgio Lombardo,
  • Annarita Signoriello,
  • Giovanni Corrocher,
  • Caterina Signoretto and ,
  • Gloria Burlacchini,
  • Alessia Pardo and
  • Pier Francesco Nocini
  • + 2 authors+ 0 author

In patients presenting mucositis, effective sub-gingival debridement is crucial to prevent peri-implantitis. The aim of this randomized study was to assess the three-month (T1) effects of a locally delivered liquid desiccant agent with molecular hygr...

(This article belongs to the Special Issue Antibiotics and Antimicrobials in Dentistry)
  • Article
  • Open Access
12 Citations
3,505 Views
20 Pages

15 August 2025

Background: Immediate implant placement in the esthetic zone, particularly in Class II extraction sockets with partial facial bone loss, presents challenges in achieving soft and hard tissue stability. Customized computer-aided design/computer-aided...

  • Article
  • Open Access
5 Citations
3,286 Views
9 Pages

Histological and Immunohistochemical Analysis of Peri-Implant Soft and Hard Tissues in Patients with Peri-Implantitis

  • Valentina Flores,
  • Bernardo Venegas,
  • Wendy Donoso,
  • Camilo Ulloa and ,
  • Alejandra Chaparro,
  • Vanessa Sousa and
  • Víctor Beltrán
  • + 2 authors+ 0 author

Currently, researchers are focused on the study of cytokines as predictive biomarkers of peri-implantitis (PI) in order to obtain an early diagnosis and prognosis, and for treatment of the disease. The aim of the study was to characterize the peri-im...

(This article belongs to the Special Issue Periodontal and Peri-Implant Diseases)
  • Article
  • Open Access
55 Citations
11,519 Views
10 Pages

Peri-Implant Soft Tissue Conditioning by Means of Customized Healing Abutment: A Randomized Controlled Clinical Trial

  • Mario Beretta,
  • Pier Paolo Poli,
  • Silvia Pieriboni,
  • Sebastian Tansella and ,
  • Mattia Manfredini,
  • Marco Cicciù and
  • Carlo Maiorana
  • + 2 authors+ 0 author

19 September 2019

Introduction: An optimal aesthetic implant restoration is a combination of a visually pleasing prosthesis and adequate surrounding peri-implant soft tissue architecture. This study describes a novel workflow for one-step formation of the supra-implan...

(This article belongs to the Special Issue Dental Implants and Materials)
  • Article
  • Open Access
13 Citations
5,476 Views
17 Pages

In fully edentulous patients, the support of a lower dental prosthesis by two implants could improve the chewing ability, retention, and stability of the prosthesis. Despite high success rates of dental implants, complications, such as peri-implantit...

(This article belongs to the Special Issue Osseointegrated Oral implants: Mechanisms of Implant Anchorage, Threats and Long-Term Survival Rates)
  • Conference Report
  • Open Access
11 Citations
5,618 Views
13 Pages

Consensus Report by the Italian Academy of Osseointegration on the Importance of Peri-Implant Soft Tissues

  • Eriberto Bressan,
  • Giovanni Zucchelli,
  • Grazia Tommasato,
  • Paolo Pesce and ,
  • Luigi Canullo,
  • Consensus Meeting Group IAO and
  • Maria Gabriella Grusovin
  • + 2 authors+ 0 author

26 August 2024

Background and Objectives: The influence of the quantity and quality of peri-implant soft tissue on implant health and long-term maintenance is controversial. This consensus aimed to assess the importance of peri-implant soft tissue by analyzing four...

(This article belongs to the Section Dentistry and Oral Health)
  • Article
  • Open Access
62 Citations
6,350 Views
14 Pages

Impact of Implant Surface Material and Microscale Roughness on the Initial Attachment and Proliferation of Primary Human Gingival Fibroblasts

  • Marco Aoqi Rausch,
  • Hassan Shokoohi-Tabrizi,
  • Christian Wehner,
  • Benjamin E. Pippenger and ,
  • Raphael S. Wagner,
  • Christian Ulm,
  • Andreas Moritz,
  • Jiang Chen and
  • Oleh Andrukhov
  • + 4 authors+ 0 author

22 April 2021

Due to the rising demand for zirconia (Zr) based implant systems, it is important to understand the impact of Zr and titanium (Ti) implants and particularly their topography on soft tissue healing. As human gingival fibroblasts (hGFs) are the predomi...

(This article belongs to the Special Issue New Trends in Bioengineering in Osseointegration and Dental Implants)
  • Article
  • Open Access
11 Citations
3,245 Views
12 Pages

16 October 2020

Despite high success rates of dental implants, surface exposure may occur as a consequence of biologic width establishment associated with surgery. This prospective split-mouth study evaluated the effect of early implant surface exposure caused by in...

(This article belongs to the Special Issue Clinical Advances in Implant Dentistry)
  • Article
  • Open Access
8 Citations
3,506 Views
17 Pages

Disparity in the Influence of Implant Provisional Materials on Human Gingival Fibroblasts with Different Phases of Cell Settlement: An In Vitro Study

  • Takanori Matsuura,
  • Stella Stavrou,
  • Keiji Komatsu,
  • James Cheng and ,
  • Alisa Pham,
  • Stephany Ferreira,
  • Tomomi Baba,
  • Ting-Ling Chang,
  • Denny Chao and
  • Takahiro Ogawa
  • + 5 authors+ 0 author

21 December 2023

The development of healthy peri-implant soft tissues is critical to achieving the esthetic and biological success of implant restorations throughout all stages of healing and tissue maturation, starting with provisionalization. The purpose of this st...

(This article belongs to the Special Issue Recent Process Design and Development Strategies for Dental Materials)
  • Article
  • Open Access
1 Citations
2,155 Views
13 Pages

Effects of Different Titanium Anodized Surfaces on Peri-Implant Soft Tissue Healing Around Dental Abutments: In Vitro and Proteomic Study

  • Francisco Romero-Gavilán,
  • Andreia Cerqueira,
  • Carlos Arias-Mainer,
  • David Peñarrocha-Oltra and ,
  • Claudia Salavert-Martínez,
  • Juan Carlos Bernabeu-Mira,
  • Iñaki García-Arnáez,
  • Félix Elortza,
  • Mariló Gurruchaga and
  • Julio Suay
  • + 6 authors+ 1 author

30 June 2025

Objectives: This study aimed to evaluate the effects of different titanium (Ti) anodized surfaces on soft tissue healing around dental implant abutments. Methods: Discs of machined (MC), pink anodized (PA) and yellow anodized (YA) surfaces were morph...

(This article belongs to the Special Issue Application of Advanced Therapies in Oral Health)
  • Review
  • Open Access

3 November 2026

Improvements in early biological responses to engineered dental implant surfaces have not consistently translated into superior long-term survival, marginal bone stability, or prevention of peri-implant disease relative to contemporary surfaces. This...

(This article belongs to the Special Issue Engineering Regeneration: Biomaterials, Biology, and Translation)

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