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Applied Sciences
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Innovative Techniques and Materials in Implant Dentistry
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Innovative Techniques and Materials in Implant Dentistry

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Dentistry and Oral Sciences".

Deadline for manuscript submissions: 30 July 2026 | Viewed by 2335

Special Issue Editors

Dr. Alexandre Perez

E-Mail Website
Guest Editor
Unit of Oral Surgery and Implantology, Division of Oral and Maxillofacial Surgery, Department of Surgery, Faculty of Medicine, University Hospitals of Geneva, University of Geneva, 1205 Geneva, Switzerland
Interests: oral implantology; surgical procedures in implantology; sinus lift and implants; digital planning and therapy methods in implant surgery; peri-implantitis; biomaterials and bone regeneration; osseointegration; morphology analysis of dental implants
Prof. Dr. Roberto Di Felice

E-Mail Website
Guest Editor
Private Practice, Studio Roberto di Felice, Viale Buozzi 6, 63074 San Benedetto del Tronto, Italy
Interests: regenerative techniques and biomaterial role in dental implantology; oral surgical procedures; thermal risks during drilling procedures; digital implantology and guided dental implant surgery; preprosthetic workflow in implant superstructure; peri-implantitis diagnosis and treatment
Dr. Tommaso Lombardi

E-Mail Website
Guest Editor
Unit of Oral Medicine and Oral Maxillofacial Pathology, Division of Oral and Maxillofacial Surgery, Department of Surgery, Faculty of Medicine, University Hospitals of Geneva, University of Geneva, 1205 Geneva, Switzerland
Interests: oral soft tissue pathology; oral dermatology; oral cancer; oral precancerous lesions; odontogenic cysts and tumors; oral and peri-implant tissues histology and histopathology

Special Issue Information

Dear Colleagues,

Dental implantology stands at the forefront of modern dentistry, representing the primary and preferred treatment for replacing missing teeth.

The global dental implant market is experiencing rapid growth, with research into this field continuing to make significant advancements.

New dental implants and improvements in surgical procedures, dental materials, digital dentistry and research techniques have enhanced clinician workflows and the standard of care provided to patients, thereby improving treatment quality and outcomes. Some developments in robotic dental implant surgery that may have seemed futuristic a few years ago have now become a reality.

We would like to invite you to contribute to an upcoming Special Issue titled "Innovative Techniques and Materials in Implant Dentistry". This Special Issue seeks the submission of original research, review articles, and case studies that cover the latest advancements in basic, clinical and translational research in the field of implant dentistry.

Potential topics include, but are not limited, to the following:

  • Dental implants materials and design;
  • Surgical techniques for the placement of dental implants;
  • Clinical in vivo and in vitro studies;
  • The use of digital dentistry in implantology;
  • Biomaterials in implant dentistry and osseous regeneration;
  • Regenerative techniques in peri-implant tissue augmentation;
  • Diseases of peri-implant tissues and their management;
  • New concepts and future research strategies in dental implantology.

We look forward to receiving your manuscripts. We hope that this Special Issue will improve our scientific understanding of implant dentistry and patient treatment.

Dr. Alexandre Perez
Prof. Dr. Roberto Di Felice
Dr. Tommaso Lombardi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • dental implants
  • biomaterial
  • surgical procedures
  • osseointegration
  • peri-implantitis
  • robotic dental implant surgery
  • digital dentistry
  • implant guides
  • implant placement
  • preparation of heat generation at implant site

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (4 papers)

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Research

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14 pages, 1910 KB  
Article
Effect of Additively Manufactured Sphene Ceramic Scaffolds on Bone Response in Rat Critical-Size Calvarial Defects
by Giulia Brunello, Hamada Elsayed, Lucia Schiavon, Elia Sbettega, Giovanna Iezzi, Barbara Zavan, Simone Carmignato, Enrico Bernardo, Lisa Biasetto and Stefano Sivolella
Appl. Sci. 2026, 16(7), 3121; https://doi.org/10.3390/app16073121 - 24 Mar 2026
Viewed by 340
Abstract
Silica-based bioceramics are promising bone substitutes with tunable degradation and mechanical properties. We aimed to assess bone response in critical-size calvarial defects in rats, empty or filled with 3D-printed sphene ceramic (CaTiSiO5) scaffolds produced using direct ink writing from preceramic polymers [...] Read more.
Silica-based bioceramics are promising bone substitutes with tunable degradation and mechanical properties. We aimed to assess bone response in critical-size calvarial defects in rats, empty or filled with 3D-printed sphene ceramic (CaTiSiO5) scaffolds produced using direct ink writing from preceramic polymers and reactive fillers. Scaffold characterization was performed using scanning electron microscopy, X-ray diffraction, porosity analysis, and compressive strength testing. Bilateral cylindrical 5 mm calvarial defects were created in 20 rats: one was randomly filled with sphene scaffold, while the contralateral remained empty. Ten animals were killed at 4 weeks, the rest at 8 weeks. Specimens were collected for micro-X-ray computed tomography (micro-CT) analysis, followed by undecalcified histology. The scaffolds exhibited porous structure with complete sphene phase purity and compressive strength of 17.91 MPa (SD 4.6). In vivo, no adverse event was noted during healing. Overall bone regeneration—as measured by BV/TV—was comparable between groups: Bone volume/total volume (BV/TV) increased over time in the empty and sphene groups, reaching ~40%, with no significant differences between groups or time points. BV/TV was significantly higher in the external regions of the defects compared to the internal areas in both groups at the two time points. The sphene group showed a significantly greater volume of new bone extending beyond the original cortical boundary at both 4 and 8 weeks (p = 0.013). In the sphene group histology revealed partial bone ingrowth within the scaffold, while bone in the control group was limited to defect edges. After 8 weeks, new bone adjacent to the cortical surface was thicker in the sphene group (p < 0.05). These initial findings are consistent with prior preclinical studies, supporting the biocompatibility and osteoconductive nature of sphene ceramic scaffolds. Full article
(This article belongs to the Special Issue Innovative Techniques and Materials in Implant Dentistry)
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10 pages, 652 KB  
Article
Impact of Abutment Angulation and Crown–Implant Ratio on Peri-Implant Bone Loss Severity in Posterior Internal-Connection Implants: A Two-Year Retrospective Study
by Yeon-Joo Ha, Yong-Gun Kim, Sung-Min Hwang and Jae-Mok Lee
Appl. Sci. 2026, 16(5), 2171; https://doi.org/10.3390/app16052171 - 24 Feb 2026
Viewed by 431
Abstract
Prosthetic factors, including abutment angulation and the crown–implant ratio (CIR), have been suggested to influence peri-implant marginal bone loss; however, their long-term effects remain unclear. This study aimed to evaluate the pattern of peri-implant bone loss over 2 years and to analyze the [...] Read more.
Prosthetic factors, including abutment angulation and the crown–implant ratio (CIR), have been suggested to influence peri-implant marginal bone loss; however, their long-term effects remain unclear. This study aimed to evaluate the pattern of peri-implant bone loss over 2 years and to analyze the clinical relevance of abutment angulation and CIR. A total of 200 posterior internal-connection implants placed between 2017 and 2021 were retrospectively evaluated using standardized periapical radiographs taken at baseline, 6 months, 1 year, and 2 years after loading. Bone level changes were measured mesially and distally and average per implant. Patients were categorized according to abutment angulation (<30° or ≥30°) and CIR (<1:1.5 or ≥1:1.5). The mean marginal bone loss increased during the first year (0.61 mm at 6 months to 1.08 mm at 1 year) and remained stable thereafter (1.12 mm at 2 years). Significantly greater bone loss was observed in implants restored with abutment angulation ≥ 30° (p < 0.05), whereas CIR showed no significant association at any time point (p > 0.05). No interaction effect was found between the two variables. Most peri-implant bone remodeling occurred within the first year after loading, followed by a stable phase. Abutment angulation of ≥30° was associated with increased bone loss, while CIR alone did not demonstrate clinical significance. When possible, minimizing abutment angulation may help improve long-term peri-implant bone stability. Full article
(This article belongs to the Special Issue Innovative Techniques and Materials in Implant Dentistry)
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12 pages, 2090 KB  
Article
Preliminary Evaluation of a High-Class Treatment Dental Implant Surface: A TOF-SIMS Study
by Vincenzo Ronsivalle, Salvatore Bocchieri, Antonino Licciardello, Gabriele Cervino, Cesare D’Amico, Pierluigi Mariani and Marco Cicciù
Appl. Sci. 2026, 16(4), 1936; https://doi.org/10.3390/app16041936 - 14 Feb 2026
Viewed by 368
Abstract
Background: Surface chemistry and cleanliness are widely regarded as important factors influencing the host response to titanium dental implants. Despite advances in manufacturing and sterilization, trace residues may persist at the nanoscale even in commercially sterile devices. This study provides a preliminary evaluation [...] Read more.
Background: Surface chemistry and cleanliness are widely regarded as important factors influencing the host response to titanium dental implants. Despite advances in manufacturing and sterilization, trace residues may persist at the nanoscale even in commercially sterile devices. This study provides a preliminary evaluation of premium-grade titanium dental implants using time-of-flight secondary ion mass spectrometry (ToF-SIMS) to assess surface chemical uniformity and trace contaminant distribution. Method: Two commercially available titanium implants from Schütz Dental were analyzed under static and dynamic ToF-SIMS modes using Bi3+ and Cs+ ion beams. Both positive and negative ion spectra were collected to identify elemental and molecular species. Chemical mapping and depth profiling were performed to evaluate contaminant distribution and surface depth composition. Results: In the two implants analyzed, the surfaces were dominated by TiO+ and TiO2+ species, consistent with a native titanium oxide layer. In both analyzed implants, localized contaminants—including fluorine, chlorine, sulfur, CN groups, and organic residues—were detected within the outermost ~0.1 µm. These signals showed heterogeneous distribution along the thread-related regions within the analyzed ROIs, compatible with residues originating from machining, surface treatments, packaging, and/or sterilization steps. Conclusions: The present data support only the descriptive finding that trace contaminants were detected on the two analyzed implants. ToF-SIMS enabled nanoscale chemical mapping and depth profiling of these residues, supporting the feasibility of this approach for trace-level surface auditing and hypothesis generation. Any biological/clinical implications remain speculative and require dedicated in vitro/in vivo validation on larger sample sets. Full article
(This article belongs to the Special Issue Innovative Techniques and Materials in Implant Dentistry)
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Other

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28 pages, 1929 KB  
Systematic Review
Implant-Supported Auricular Prostheses: Current Evidence and a Six-Year Clinical Case Report with Navigated Flapless Placement
by Gerardo Pellegrino, Leonardo Ciocca, Carlo Barausse, Subhi Tayeb, Claudia Angelino, Martina Sansavini and Pietro Felice
Appl. Sci. 2026, 16(3), 1192; https://doi.org/10.3390/app16031192 - 23 Jan 2026
Viewed by 623
Abstract
Background: Auricular defects resulting from congenital anomalies, trauma, or oncologic resection pose significant functional and psychosocial challenges. When autologous reconstruction is not feasible or not desired, implant-retained auricular prostheses represent a reliable alternative with high patient satisfaction. This study aimed to systematically [...] Read more.
Background: Auricular defects resulting from congenital anomalies, trauma, or oncologic resection pose significant functional and psychosocial challenges. When autologous reconstruction is not feasible or not desired, implant-retained auricular prostheses represent a reliable alternative with high patient satisfaction. This study aimed to systematically evaluate the clinical performance of craniofacial implants used for auricular prosthetic rehabilitation, focusing on implant survival, prosthetic outcomes, workflow typologies, and complications. A secondary objective was to illustrate the long-term validity of a minimally invasive navigation technique through a clinical case with 6-year follow-up. Methods: A systematic review was conducted according to PRISMA guidelines. Clinical studies published between 2005 and 2025 reporting outcomes of implant-retained auricular prostheses were searched in PubMed and Scopus databases. Data were extracted on implant type, survival rates, prosthetic performance, workflow, and complications. Risk of bias was assessed using appropriate tools based on each study design. Results: A total of thirty-two studies were included, comprising fifteen case reports, fifteen case series, one cohort study, and one prospective observational study. Implant survival was consistently high across all workflow categories, with failures predominantly associated with irradiated or anatomically compromised bone. Prosthetic outcomes were favorable, showing excellent esthetics, stable retention, and high patient satisfaction irrespective of manufacturing method, although digital and navigation-assisted workflows improved reproducibility, symmetry, and planning precision. Complication rates were low and generally limited to mild peri-abutment inflammation manageable with conservative care. The clinical case confirmed these findings, showing stable osseointegration, healthy soft tissues, and uncompromised prosthetic function at 6-year follow-up. Conclusions: Implant-retained auricular prostheses show predictable long-term success, independent of whether traditional, hybrid, or fully digital workflows are employed. Digital technologies enhance surgical accuracy, minimize morbidity, and streamline prosthetic fabrication, although high-quality comparative studies remain limited. Full article
(This article belongs to the Special Issue Innovative Techniques and Materials in Implant Dentistry)
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