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14 pages, 1526 KB  
Article
Antibiotic and Copper Sensitivity in Erwinia amylovora Isolates from Northern Saudi Arabia, and the Induction of Fire Blight Suppression by Salicylic Acid
by Ali A. Al Masrahi, Abdurrehman M. Rafique, Abdullah F. Al Hashel, Mohammed A. Al Saleh and Yasser E. Ibrahim
Plants 2025, 14(20), 3192; https://doi.org/10.3390/plants14203192 - 17 Oct 2025
Abstract
Fire blight, caused by Erwinia amylovora, is a severe disease impacting pome fruit production worldwide, including in Saudi Arabia. This study evaluated antibiotic sensitivity and the potential of chemical and elicitor treatments to suppress E. amylovora isolates collected from various regions in [...] Read more.
Fire blight, caused by Erwinia amylovora, is a severe disease impacting pome fruit production worldwide, including in Saudi Arabia. This study evaluated antibiotic sensitivity and the potential of chemical and elicitor treatments to suppress E. amylovora isolates collected from various regions in Saudi Arabia. In the in vitro assays, at low antibiotic levels (10 µg/mL streptomycin and 25 µg/mL oxytetracycline), all Saudi Arabian strains exhibited minimal inhibition (zones ≤ 14 mm). Two isolates displayed partial tolerance at an intermediate oxytetracycline concentration (50 µg/mL). True sensitivity (zones > 18 mm) was mainly observed at the highest tested oxytetracycline dose (100 µg/mL). Regarding copper sulfate, all isolates showed no inhibition between 0.02 and 0.08 mM, while all isolates exhibited intermediate susceptibility at 0.16 mM. The second experimental phase examined in planta effects of streptomycin, salicylic acid (SA), and their combination on disease development in artificially inoculated apple (Malus domestica) shoots under greenhouse conditions. Both streptomycin and SA significantly reduced fire blight incidence (by 75%) and symptom severity, while the combined treatment yielded the greatest reduction in shoot necrosis and bacterial load. This is the first report demonstrating that SA, particularly when used in combination with streptomycin, can effectively suppress fire blight in Saudi Arabia. These results stress the importance of integrating resistance inducers into fire blight management strategies to counter the rise in antimicrobial resistance. Full article
(This article belongs to the Special Issue Occurrence and Control of Plant Bacterial Diseases)
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16 pages, 7284 KB  
Article
Fretting Friction and Wear Characteristics of the Internal Spiral Contact Steel Wires in the Hoisting Wire Rope Under Different Service Conditions
by Kun Huang, Gongning Li, Xiangdong Chang, Zhou Zhou, Yuxing Peng and Ran Deng
Lubricants 2025, 13(10), 453; https://doi.org/10.3390/lubricants13100453 - 17 Oct 2025
Abstract
As a critical load-bearing component in mine hoisting systems, the service performance and lifespan of wire ropes are limited by the fretting wear behavior among their internal wires and strands. To investigate the effect of fretting parameters on the wear mechanisms in wire [...] Read more.
As a critical load-bearing component in mine hoisting systems, the service performance and lifespan of wire ropes are limited by the fretting wear behavior among their internal wires and strands. To investigate the effect of fretting parameters on the wear mechanisms in wire ropes, this paper systematically conducts fretting wear experiments on multi-wire contact pairs under varying fretting frequencies and tensile loads. The results show that as the fretting frequency increases from 0.5 Hz to 3.0 Hz, the coefficient of friction (COF) rises, with its steady-state value reaching approximately 0.65. Conversely, as the tension decreases from 150 N to 90 N, the COF increases, attaining a steady-state value of 0.71. The slip regime between the steel wires evolves from gross slip to partial slip with increasing frequency. With an increase in tensile load, the slip regime transitions from gross slip to partial slip and finally to adhesion. Higher fretting frequencies and greater tensile loads exacerbate both the wear rate and the severity of damage on the spiral contact wires inside the hoisting rope. The highest wear rate, 27.2 × 10−6 mm3/N·m, is observed at 3.0 Hz, while the maximum wear rate under tension is 39.6 × 10−6 mm3/N·m at 150 N. The dominant wear mechanisms at higher frequencies are abrasive wear, tribochemical reaction, and surface fatigue. Under greater tension, the primary wear mechanisms are abrasive wear, surface fatigue, and tribochemical reaction. Full article
(This article belongs to the Special Issue Tribological Behavior of Wire Rope)
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17 pages, 1916 KB  
Article
Comparative Performance of Green Roof Systems with Smart Cisterns: Balancing Stormwater Capture and Irrigation Supply
by Nandan H. Shetty, Mark Wang, Robert M. Elliott and Patricia J. Culligan
Water 2025, 17(20), 2987; https://doi.org/10.3390/w17202987 - 16 Oct 2025
Abstract
Using five years of field monitoring data, this study compares two types of roof systems that combine green roofs, cisterns, and real-time control (RTC) strategies: one optimized to reduce stormwater runoff (a fully vegetated roof with cisterns operating under a “smart detention” [SD] [...] Read more.
Using five years of field monitoring data, this study compares two types of roof systems that combine green roofs, cisterns, and real-time control (RTC) strategies: one optimized to reduce stormwater runoff (a fully vegetated roof with cisterns operating under a “smart detention” [SD] logic that fully empties within 24 h), and one designed to balance architectural, economic, and structural tradeoffs (a half vegetated, half bare roof with cisterns operating under a “rainwater harvesting” [RWH] logic that partially drains in anticipation of rainfall while maintaining a reserve for green roof irrigation). Both configurations demonstrated strong stormwater performance, with cisterns improving roof retention by 10.2 to 13.0% over five years. For small to medium storms (under 25 mm), representing 71.2% of events, both strategies prevented more than 95% of runoff, while forecast accuracy primarily influenced larger events. Even with modest cistern sizing, the SD system captured 96.7% and the RWH system 95.8% of runoff from small to medium storms, approaching 100% assuming perfect weather forecasts. Irrigation analysis showed that RWH cisterns supplied ~51% of irrigation demand, increasing to ~70% under perfect forecasts. This study is among the first to compare stormwater and irrigation outcomes from side-by-side RTC-managed roof systems over multiple years. The results underscore that the mixed green/bare roof with RWH logic provides nearly equivalent stormwater benefits while offering added value through irrigation supply, reduced structural loading, and design flexibility. Full article
(This article belongs to the Special Issue Stormwater Management in Sponge Cities)
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13 pages, 252 KB  
Article
Assessment of Longitudinal Measurement Invariance of Short Versions of the CES-D in Maternal Caregivers
by Luis Villalobos-Gallegos, Salvador Trejo, Diana Mejía-Cruz, Aldebarán Toledo-Fernández and Diana Alejandra González García
Psychiatry Int. 2025, 6(4), 126; https://doi.org/10.3390/psychiatryint6040126 - 16 Oct 2025
Abstract
We tested the longitudinal invariance of seven short versions of the Center for Epidemiological Studies Depression Scale (CES-D) in maternal caregivers, following recent analytic recommendations for ordered categorical responses. Data for this study were drawn from the Longitudinal Studies in Child Abuse and [...] Read more.
We tested the longitudinal invariance of seven short versions of the Center for Epidemiological Studies Depression Scale (CES-D) in maternal caregivers, following recent analytic recommendations for ordered categorical responses. Data for this study were drawn from the Longitudinal Studies in Child Abuse and Neglect (LONGSCAN) consortium, based on responses from 427 maternal caregivers across five waves corresponding to their children’s ages: 4, 6, 12, 14, and 16 years. We employed a comprehensive approach using differences in two approximate fit indices (CFI and RMSEA), the chi-square difference test (χ2), and a sensitivity analysis based on predicted response differences. Only one version demonstrated full invariance across all levels, while the others showed only partial evidence for loading or threshold invariance. These findings highlight concerns regarding the use of brief CES-D versions in longitudinal research, particularly over extended time periods. They also underscore the need to reassess whether item content aligns with current definitions of depressive syndrome. Our results suggest that evaluating the longitudinal invariance of short depression measures is essential to ensure the validity of conclusions about changes over time. Full article
13 pages, 3509 KB  
Article
Sol–Gel Synthesis and Multi-Technique Characterization of Graphene-Modified Ca2.95Eu0.05Co4Ox Nanomaterials
by Serhat Koçyiğit
Polymers 2025, 17(20), 2767; https://doi.org/10.3390/polym17202767 - 16 Oct 2025
Abstract
This study employs a multi-technique approach to elucidate how graphene incorporation affects phase formation, microstructure, and thermal behavior in PVA-assisted sol–gel synthesized Ca2.95Eu0.05Co4Ox nanomaterials. XRD confirms the preservation of the primary phases (hexagonal CaCO3 and [...] Read more.
This study employs a multi-technique approach to elucidate how graphene incorporation affects phase formation, microstructure, and thermal behavior in PVA-assisted sol–gel synthesized Ca2.95Eu0.05Co4Ox nanomaterials. XRD confirms the preservation of the primary phases (hexagonal CaCO3 and cubic CoO) alongside a distinct graphene (002) reflection; a systematic low-angle shift of the calcite (104) peak evidences partial relaxation of residual lattice strain with increasing graphene content, while Scherrer analysis indicates tunable crystallite size. Raman spectroscopy corroborates graphene incorporation through pronounced D (~1300 cm−1) and G (~1580 cm−1) bands and supports the XRD-identified phase coexistence via cobalt-oxide and calcite vibrations in the 200–700 cm−1 region, also indicating increased defect/disorder with graphene loading. SEM shows grain refinement, denser/bridged lamellar textures, and reduced porosity at low–moderate graphene contents (1–3 wt.%), contrasted by agglomeration-driven heterogeneity at higher loadings (5–7 wt.%). EDX reveals increasing carbon with Ca/Co redistribution at accessible surfaces, and TG–DSC corroborates the removal of oxygen-containing groups and oxidative combustion of graphene at mid temperatures. Collectively, Raman–XRD-consistent evidence demonstrates that graphene provides a tunable handle over lattice strain, crystallite size, and grain-boundary architecture, establishing a processing–composition basis for optimizing functional (e.g., electrical/thermoelectric) performance. Full article
(This article belongs to the Special Issue Polymers in Inorganic Chemistry: Synthesis and Applications)
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15 pages, 1926 KB  
Article
Metasurface-Engineered Glass for Green Buildings
by Tunchien Teng and Min Peng
Appl. Sci. 2025, 15(20), 11062; https://doi.org/10.3390/app152011062 - 15 Oct 2025
Abstract
This study numerically investigates and designs, through electromagnetic and ray-tracing simulations, two types of double-sided metasurface thermal insulation glazing to maintain visible light (VIS) transmittance while effectively suppressing near-infrared (NIR) transmission, with a partial reduction in deep-blue (DB) transmission, thus reducing air-conditioning load [...] Read more.
This study numerically investigates and designs, through electromagnetic and ray-tracing simulations, two types of double-sided metasurface thermal insulation glazing to maintain visible light (VIS) transmittance while effectively suppressing near-infrared (NIR) transmission, with a partial reduction in deep-blue (DB) transmission, thus reducing air-conditioning load and lighting energy consumption and contributing to overall building energy efficiency. Both designs were optimized and analyzed entirely through simulations, using structural parameter sweeps and AM 1.5 solar spectrum weighting. Design I is composed of two all-dielectric metasurfaces, aiming to maximize VIS transmittance while partially suppressing DB and reducing NIR transmission. Design II integrates a metallic layer with dielectric structures on the front side and employs an all-dielectric metasurface on the back side to enhance NIR blocking and maintain low transmittance under oblique incidence. Simulation results show that Design II outperforms Design I in NIR suppression, exhibiting lower and more stable transmittance across incident angles, while Design I achieves higher VIS transmittance. These findings present a promising pathway for developing high-performance, lightweight glazing for sustainable buildings, improving energy efficiency by balancing solar heat control and daylight utilization. Full article
(This article belongs to the Section Green Sustainable Science and Technology)
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19 pages, 784 KB  
Article
First Assessment of Oral Iron Chelator HBED Increases Iron Excretion in Black Rhinoceros (Diceros bicornis minor)
by Kathleen E. Sullivan, Shana R. Lavin, Lori K. Warren, Natalie D. Mylniczenko, Shannon E. Livingston, Mitchell D. Knutson and Eduardo V. Valdes
Animals 2025, 15(20), 2987; https://doi.org/10.3390/ani15202987 - 15 Oct 2025
Abstract
Black rhinoceros (Diceros bicornis) face threats to survival due to poaching in the wild and an incomplete understanding of preventive health monitoring under human care. Black rhinos under human care develop iron overload disorder (IOD) which is associated with predisposition to [...] Read more.
Black rhinoceros (Diceros bicornis) face threats to survival due to poaching in the wild and an incomplete understanding of preventive health monitoring under human care. Black rhinos under human care develop iron overload disorder (IOD) which is associated with predisposition to other disease, compromised immune function, hemolytic crisis, and death. Management of IOD is challenging but has been mitigated in some cases with dietary intervention and phlebotomy and documented through serum biomarker evaluation. Chelation therapy to reduce iron is rare in rhinos partially because of limited product availability and route of administration. An iron-specific chelator HBED (N,N’-Di(2-hydroxybenzyl)ethylenediamine-N,N’-diacetic acid) was investigated for oral use in southern black rhinos (n = 3) after successful testing was performed with equids as a model. Using a cross-over design, we tested the efficacy of short-term HBED administration. HBED was dosed at 40 mg/kg body weight for 10 days and resulted in increased urinary excretion of iron but unaltered fecal iron excretion in rhinos compared to control trials. Two rhinos maintained blood chemistry and cell distribution considered normal for the species. The third rhino experienced a hemolytic event after stopping HBED administration in the same time frame and at the same dose as the two conspecifics but fully recovered. Careful monitoring and tapering the drug at the completion of treatment is warranted, especially if the rhino’s iron load is considered high. HBED’s potential to induce iron excretion safely, as well as prevent excessive dietary iron uptake, may significantly benefit the black rhino population under human care. Full article
(This article belongs to the Section Mammals)
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39 pages, 10642 KB  
Article
An Optimal Two-Stage Tuned PIDF + Fuzzy Controller for Enhanced LFC in Hybrid Power Systems
by Saleh Almutairi, Fatih Anayi, Michael Packianather and Mokhtar Shouran
Sustainability 2025, 17(20), 9109; https://doi.org/10.3390/su17209109 (registering DOI) - 14 Oct 2025
Viewed by 196
Abstract
Ensuring reliable power system control demands innovative architectural solutions. This research introduces a fault-tolerant hybrid parallel compensator architecture for load frequency control (LFC), combining a Proportional–Integral–Derivative with Filter (PIDF) compensator with a Fuzzy Fractional-Order PI-PD (Fuzzy FOPI–FOPD) module. Particle Swarm Optimization (PSO) determines [...] Read more.
Ensuring reliable power system control demands innovative architectural solutions. This research introduces a fault-tolerant hybrid parallel compensator architecture for load frequency control (LFC), combining a Proportional–Integral–Derivative with Filter (PIDF) compensator with a Fuzzy Fractional-Order PI-PD (Fuzzy FOPI–FOPD) module. Particle Swarm Optimization (PSO) determines optimal PID gains, while the Catch Fish Optimization Algorithm (CFOA) tunes the Fuzzy FOPI–FOPD parameters—both minimizing the Integral Time Absolute Error (ITAE) index. The parallel compensator structure guarantees continuous operation during subsystem faults, substantially boosting grid reliability. Rigorous partial failure tests confirm uncompromised performance-controlled degradation. Benchmark comparisons against contemporary controllers reveal the proposed architecture’s superiority, quantifiable through transient metric enhancements: undershoot suppression (−9.57 × 10−5 p.u. to −1.17 × 10−7 p.u.), settling time improvement (8.8000 s to 3.1511 s), and ITAE reduction (0.0007891 to 0.0000001608), verifying precision and stability gains. Resilience analyses across parameter drift and step load scenarios, simulated in MATLAB/Simulink, demonstrate superior disturbance attenuation and operational stability. These outcomes confirm the solution’s robustness, dependability, and field readiness. Overall, this study introduces a transformative LFC strategy with high practical viability for modern power networks. Full article
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17 pages, 1191 KB  
Article
Psychopathological Risk During Adolescent Study-Abroad: A Larger-Cohort Update of a Previous Longitudinal Study
by Silvia Cimino and Luca Cerniglia
Eur. J. Investig. Health Psychol. Educ. 2025, 15(10), 210; https://doi.org/10.3390/ejihpe15100210 - 14 Oct 2025
Viewed by 152
Abstract
This article updates and extends a prior longitudinal study on adolescents’ psychological adjustment during short-term study-abroad programs, analyzing a newly collected larger cohort with the same design and measures. Using the same assessment schedule (pre-departure, mid-sojourn, post-return) with a larger cohort, we confirmed [...] Read more.
This article updates and extends a prior longitudinal study on adolescents’ psychological adjustment during short-term study-abroad programs, analyzing a newly collected larger cohort with the same design and measures. Using the same assessment schedule (pre-departure, mid-sojourn, post-return) with a larger cohort, we confirmed the adequate reliability and longitudinal comparability of the Teacher’s Report Form. Mean-level analyses replicated earlier patterns: internalizing symptoms increased during the sojourn and remained elevated at reentry, whereas externalizing problems followed an inverted-U, rising abroad and returning to baseline after return. Person-centered models identified three trajectory classes for both domains: a low-stable group, a transient-elevated group showing a mid-sojourn spike with subsequent recovery, and a small high-persistent group with enduring elevations. Clinical threshold transitions showed a temporary mid-sojourn rise in borderline/clinical cases for both domains, with partial normalization after return. Reliable-change estimates further distinguished transient from sustained change. Together, the findings characterize studying abroad as a moderate, time-bound stressor for most adolescents, with a minority at persistent risk. The implications of these findings include suggestions for front-loaded and reentry supports, pre-departure screening, and targeted mid-sojourn monitoring. The strengths include longitudinal measurement invariance and person-centered modeling; the limitations include teacher-only reports and a short post-return follow-up. Full article
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17 pages, 4052 KB  
Article
Incorporating the Effect of Windborne Debris on Wind Pressure Calculation of ASCE 7 Provisions
by Karim Farokhnia
Wind 2025, 5(4), 24; https://doi.org/10.3390/wind5040024 - 13 Oct 2025
Viewed by 70
Abstract
Windborne debris generated during tornadoes and hurricanes plays a critical role in building damage. This damage occurs either through direct impact on structural and nonstructural components or indirectly by increasing internal pressure when debris penetrates openings (e.g., windows and doors) or creates new [...] Read more.
Windborne debris generated during tornadoes and hurricanes plays a critical role in building damage. This damage occurs either through direct impact on structural and nonstructural components or indirectly by increasing internal pressure when debris penetrates openings (e.g., windows and doors) or creates new ones. These breaches can significantly raise internal pressure, even at lower wind speeds compared to debris-free conditions. Current provisions in ASCE 7, the nationally adopted standard for wind load calculations in the United States, account for factors such as building geometry, location, and exposure category. However, they do not consider the effects of windborne debris on internal pressure coefficients. This study proposes an enhancement to ASCE 7 by incorporating debris effects through the use of a more conservative enclosure classification. Real-world damage observations from three tornado-impacted residential buildings are presented, followed by a failure mechanism analysis, supporting analytical fragility data, and numerical simulations of debris effects on building damage. The findings suggest that treating buildings as Partially Enclosed under ASCE 7 can more accurately reflect debris-induced internal pressures and improve building resilience under extreme wind events. Full article
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24 pages, 6824 KB  
Article
Analytical Modeling and Simulation of Machinery Containing Hydraulic Lines with Fluid Transients
by David Hullender
Actuators 2025, 14(10), 489; https://doi.org/10.3390/act14100489 - 9 Oct 2025
Viewed by 191
Abstract
In industrial equipment containing hydraulic lines for power transmission, the lines have boundary conditions defined by components such as pumps, valves, and actuators located at the ends of the lines. Sudden changes in any of the boundary conditions may result in significant pressure/flow [...] Read more.
In industrial equipment containing hydraulic lines for power transmission, the lines have boundary conditions defined by components such as pumps, valves, and actuators located at the ends of the lines. Sudden changes in any of the boundary conditions may result in significant pressure/flow dynamics (fluid transients) in the lines that may be detrimental or favorable to the performance of the equipment. Accurate models for line transients are defined by the exact solution to a set of simultaneous partial differential equations. In this paper, analytical solutions to the partial differential equations provide Laplace transform transfer functions applicable to any set of boundary conditions yet to be specified that satisfy the requirements of causality. Analytical solutions of these partial differential equations from previous publications are reviewed for cases of laminar and turbulent flow for Newtonian and a class of non-Newtonian fluids. This paper focuses on a method for obtaining total system analytical models and time domain solutions for cases in which the end-of-line components can be modeled with linear equations for perturbations relative to pre-transient flow conditions. Examples with pumps, valves, and actuators demonstrate the process of coupling equations for components at the ends of a line to obtain total system transfer functions and then obtain time domain solutions for outputs of interest associated with system inputs and load variations. Full article
(This article belongs to the Special Issue Advances in Fluid Power Systems and Actuators)
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15 pages, 3325 KB  
Article
Impact of SiN Passivation on Dynamic-RON Degradation of 100 V p-GaN Gate AlGaN/GaN HEMTs
by Marcello Cioni, Giacomo Cappellini, Giovanni Giorgino, Alessandro Chini, Antonino Parisi, Cristina Miccoli, Maria Eloisa Castagna, Aurore Constant and Ferdinando Iucolano
Electron. Mater. 2025, 6(4), 14; https://doi.org/10.3390/electronicmat6040014 - 7 Oct 2025
Viewed by 302
Abstract
In this paper, the impact of SiN passivation on dynamic-RON degradation of AlGaN/GaN HEMTs devices is put in evidence. To this end, samples showing different SiN passivation stoichiometry are considered, labeled as Sample A and Sample B. For dynamic-RON tests, two [...] Read more.
In this paper, the impact of SiN passivation on dynamic-RON degradation of AlGaN/GaN HEMTs devices is put in evidence. To this end, samples showing different SiN passivation stoichiometry are considered, labeled as Sample A and Sample B. For dynamic-RON tests, two different experimental setups are employed to investigate the RON-drift showing up during conventional switch mode operation by driving the DUTs under both (i) resistive load and (ii) soft-switching trajectory. This allows to discern the impact of hot carriers and off-state drain voltage stress on the RON parameter drift. Measurements performed with both switching loci shows similar dynamic-RON response, indicating that hot carriers are not involved in the degradation of tested devices. Nevertheless, a significant difference was observed between Sample A and Sample B, with the former showing an additional RON-degradation mechanism, not present on the latter. This additional drift is totally ascribed to the SiN passivation layer and is confirmed by the different leakage current measured across the two SiN types. The mechanism is explained by the injection of negative charges from the Source Field-Plate towards the AlGaN surface that are captured by surface/dielectric states and partially depletes the 2DEG underneath. Full article
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15 pages, 2257 KB  
Article
The Development and Characterization of Layered Pellets Containing a Combination of Amorphized Amlodipine Besylate and Hydrochlorothiazide Using a High-Shear Granulator
by Azza A. K. Mahmoud, Krisztina Ludasi, Dorina Gabriella Dobó, Dániel Sebők, Ákos Kukovecz, Viktória Hornok, Kadosa Sajdik, Tamás Szabó, Tamás Sovány, Géza Regdon and Katalin Kristó
Pharmaceuticals 2025, 18(10), 1496; https://doi.org/10.3390/ph18101496 - 5 Oct 2025
Viewed by 342
Abstract
Background/Objective: The high-shear granulator is considered an effective piece of equipment for layering pelletization because it enhances drug amorphization and improves drug dissolution. This study aimed to apply a high-shear granulator to prepare layered pellets containing a combination of hydrochlorothiazide and amlodipine besylate [...] Read more.
Background/Objective: The high-shear granulator is considered an effective piece of equipment for layering pelletization because it enhances drug amorphization and improves drug dissolution. This study aimed to apply a high-shear granulator to prepare layered pellets containing a combination of hydrochlorothiazide and amlodipine besylate with improved physicochemical properties. Methods: Different molar ratios (2:1, 1:1, and 1:2) of the hydrochlorothiazide and amlodipine besylate mixture were deposited on the surface of the inert spheres of the microcrystalline cellulose (MCC) core by the mechanical effect of the high impeller speed. The resulting layered pellets were characterized using X-ray powder diffractometry (XRPD) and differential scanning calorimetry (DSC) to estimate the degree of the drug amorphization, and consequently a dissolution test was performed to determine the degree of the enhancement of the percentage of release. Additionally, micro-computed tomography (micro-CT) and a texture analyzer were used to determine the morphological characteristics and hardness of the resulting pellets, and then a stability study was performed. Results: On the basis of the micro-CT images, the MCC core was successfully loaded with a uniform layer of the drug combination at the pellet surface, which exhibited higher diameters than pure cellets. Furthermore, the drug combination in layered pellets was partially amorphized with a lower crystallinity percentage, a lower intensity, a broadening of the hydrochlorothiazide melting peak, and a higher cumulative release of both drugs with good stability, except pellets with a molar ratio of 1:2 that were recrystallized with a higher crystallinity percentage of 79.9%. Conclusions: Modifying the physical form and dissolution behavior of the hydrochlorothiazide and amlodipine besylate combination was achieved by single-step layering pelletization. Full article
(This article belongs to the Section Pharmaceutical Technology)
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20 pages, 8594 KB  
Article
Strength and Ductility Improvement of Low Confinement Spun Pile with Steel Jacket Strengthening
by Yuskar Lase, Mulia Orientilize, Widjojo Adi Prakoso, Jansen Reagen and Stevany Lydia Jedidjah Hugen
Infrastructures 2025, 10(10), 262; https://doi.org/10.3390/infrastructures10100262 - 3 Oct 2025
Viewed by 205
Abstract
Spun piles adjacent to the pile cap need sufficient confinement to ensure the formation of plastic hinges during severe earthquakes. However, the high confinement ratio required for precast piles according to ACI 318-19 results in tightly spaced spirals, which are difficult to implement. [...] Read more.
Spun piles adjacent to the pile cap need sufficient confinement to ensure the formation of plastic hinges during severe earthquakes. However, the high confinement ratio required for precast piles according to ACI 318-19 results in tightly spaced spirals, which are difficult to implement. Since higher confinement is only needed at specific regions of the pile, external transverse reinforcement using steel jacketing has been proposed as an alternative solution. An experimental and numerical study was conducted to evaluate the effectiveness. The experimental results showed that the jacket enhanced both the strength and energy dissipation of the connection, but had only a minor effect on its ductility. A parametric study using finite element analysis was performed to investigate the parameters influencing connection behavior. The results indicated that variations in jacket thickness did not significantly impact the connection’s performance. A jacket height equal to 1.53 times the pile diameter was found to be the maximum effective height. It was also observed that higher axial loads led to a sudden loss of connection strength, thereby reducing ductility. Partial bonding between the jacket, grout, and pile was found to be acceptable within a certain range. The numerical analysis found that the steel jacket increases the ductility. Full article
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31 pages, 9075 KB  
Article
Behaviour Analysis of Timber–Concrete Composite Floor Structure with Granite Chip Connection
by Anna Haijima, Elza Briuka, Janis Sliseris, Dmitrijs Serdjuks, Arturs Ziverts and Vjaceslavs Lapkovskis
J. Compos. Sci. 2025, 9(10), 538; https://doi.org/10.3390/jcs9100538 - 2 Oct 2025
Viewed by 631
Abstract
This study investigates the mechanical behaviour of timber–concrete composite (TCC) floor members with an innovative adhesive connection reinforced by granite chips, glass fibre yarn net in the epoxy adhesive layer, and polypropylene (PP) fibres in the concrete layer. Laboratory tests involved three groups [...] Read more.
This study investigates the mechanical behaviour of timber–concrete composite (TCC) floor members with an innovative adhesive connection reinforced by granite chips, glass fibre yarn net in the epoxy adhesive layer, and polypropylene (PP) fibres in the concrete layer. Laboratory tests involved three groups of specimens subjected to three-point bending over a span of 500 mm with specimen lengths of 550 mm. Group A specimens exhibited crack initiation at approximately 8 kN and partial disintegration at an average load of 11.17 kN, with maximum vertical displacements ranging from 1.7 to 2.5 mm at 8 kN load, increasing rapidly to 4.3 to 5 mm post-cracking. The addition of reinforcing fibres decreased the brittleness of the adhesive connection and improved load-bearing capacity. Finite element modeling using the newly developed Verisim4D software (2025 v 0.6) and analytical micromechanics approaches demonstrated satisfactory accuracy in predicting the composite behavior. This research highlights the potential of reinforcing the adhesive layer and concrete with fibres to enhance the ductility and durability of TCC members under flexural loading. Full article
(This article belongs to the Special Issue Behaviour and Analysis of Timber–Concrete Composite Structures)
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