Search Results (1,212)

The conservation and restoration of water-gilded wooden cultural heritage, such as polychrome sculptures, frames, panels, altarpieces, etc., requires the use of fillers that guarantee structural stability, physicochemical and mechanical compatibility with the original support, and the ability to adapt to dimensional movements induced by thermo-hygrometric variations. This study, conducted as part of the DorART Project, analyzed the behavior of nine formulations, both commercial and non-commercial, selected through a review of the state-of-the-art specialized literature, along with the use of participatory science, which focused on the practices and materials most commonly used by professionals in the field. The experimental design was based on three types of specimens: two with wooden supports, selected for evaluating their interaction with the original material and with the traditional water gilding technique, and a third type for analyzing the individual behavior of the tested materials. Analyses of adhesion, tensile strength, Shore C hardness, gloss, abrasion test results, wettability, pH changes, and chemical composition were performed using ATR-FTIR spectroscopy. The results showed significant differences depending on the type of curing used and the composition and aging behavior of the specimen. Some of the fillers demonstrated improved compatibility with water-based gilding, facilitating workability and providing structural strength. M3 and M9 demonstrated an optimal balance of workability and aging stability. The results of this study can help restorers select materials based on their specific needs, considering the requirements of mechanical adaptation to the substrate, compatibility, and durability. Full article

This study conducted a comprehensive evaluation of the effects of biodegradable (BD) mulching film in onion cultivation, with a focus on plant growth, yield, soil environment, weed suppression, and film degradation, in comparison to conventional polyethylene (PE) film and non-mulching (NM) treatment across multiple regions and years (2023–2024). The BD and PE films demonstrated similar impacts on onion growth, bulb size, yield, and weed suppression, significantly outperforming NM, with yield increases of over 13%. There were no consistent differences in soil pH, electrical conductivity, and physical properties in crops that used either BD or PE film. Soil temperature and moisture were also comparable regardless of which film type was used, confirming BD’s viability as an alternative to PE. However, areas that used BD film had soils which exhibited reduced microbial populations, particularly Bacillus and actinomycetes which was likely caused by degradation by-products. BD film degradation was evident from 150 days post-transplantation, with near-complete decomposition at 60 days post-burial, whereas PE remained largely intact (≈98%) during the same period. These results confirm that BD film can match the agronomic performance of PE while offering the advantage of environmentally friendly degradation. Further research should optimize BD film durability and assess its cost-effectiveness for large-scale sustainable agriculture. Full article

Due to its superior maneuverability and concealment, the micro flapping-wing aircraft has great application prospects in both military and civilian fields. However, the development and optimization of lightweight materials have always been the key factors limiting performance enhancement. This paper designs the flapping mechanism of a single-degree-of-freedom miniature flapping wing aircraft. In this study, T800 carbon fiber composite material was used as the frame material. Three typical wing membrane materials, namely polyethylene terephthalate (PET), polyimide (PI), and non-woven kite fabric, were selected for comparative analysis. Three flapping wing configurations with different stiffness were proposed. These wings adopted carbon fiber composite material frames. The wing membrane material is bonded to the frame through a coating. Inspired by bionics, a flapping wing that mimics the membrane vein structure of insect wings is designed. By changing the type of membrane material and the distribution of carbon fiber composite materials on the wing, the stiffness of the flapping wing can be controlled, thereby affecting the mechanical properties of the flapping wing aircraft. The modal analysis of the flapping-wing structure was conducted using the finite element analysis method, and the experimental prototype was fabricated by using 3D printing technology. To evaluate the influence of different wing membrane materials on lift performance, a high-precision force measurement experimental platform was built, systematic tests were carried out, and the lift characteristics under different flapping frequencies were analyzed. Through computational modeling and experiments, it has been proven that under the same flapping wing frequency, the T800 carbon fiber composite material frame can significantly improve the stiffness and durability of the flapping wing. In addition, the selection of wing membrane materials has a significant impact on lift performance. Among the test materials, the PET wing film demonstrated excellent stability and lift performance under high-frequency conditions. This research provides crucial experimental evidence for the optimal selection of wing membrane materials for micro flapping-wing aircraft, verifies the application potential of T800 carbon fiber composite materials in micro flapping-wing aircraft, and opens up new avenues for the application of advanced composite materials in high-performance micro flapping-wing aircraft. Full article

Double-suction centrifugal pumps are extensively employed in industrial applications owing to their high efficiency, low vibration, superior cavitation resistance, and operational durability. This study analyzes how impeller oblique cutting angles (0°, 6°, 9°, 12°) affect a double-suction pump at a fixed 4% trimming ratio and constant average post-trim diameter. Numerical simulations and tests reveal that under low-flow (0.7Q_d) and design-flow conditions, the flat-cut (0°) minimizes reflux ratio and maximizes efficiency by aligning blade outlet flow with the mainstream. Increasing oblique cutting angles disrupts this alignment, elevating reflux and reducing efficiency. Conversely, at high flow (1.3Q_d), the 12° bevel optimizes outlet flow, achieving peak efficiency. Pressure pulsation at the volute tongue (P11) peaks at the blade-passing frequency, with amplitudes significantly higher for 9°/12° bevels than for 0°/6°. The flat-cut suppresses wake vortices and static–rotor interaction, but oblique cutting angle choice critically influences shaft-frequency pulsation. Entropy analysis identifies the volute as the primary loss source. Larger oblique cutting angles intensify wall effects, increasing total entropy; pump chamber losses rise most sharply due to worsened outlet velocity non-uniformity and turbulent dissipation. The flat-cut yields minimal entropy at Q_d. These findings provide a basis for tailoring impeller trimming to specific operational requirements. Furthermore, the systematic analysis provides critical guidance for impeller trimming strategies in other double-suction pumps and pumps as turbines in micro hydropower plants. Full article

This study investigated the fracture behavior of asphalt mixtures under indirect tensile loading by comparing the performance of homogenized and micromechanical finite element (FEMs) models based on the cohesive zone model (CZM). Five asphalt mixture types were tested experimentally, and both models were calibrated and validated using load–displacement curves from indirect tensile tests (IDTs). The micromechanical model, incorporating random aggregate generation and three-phase material definition, exhibited significantly higher predictive accuracy (R² = 0.86–0.98) than the homogenized model (R² = 0.66–0.77). The validated micromechanical model was further applied to quantify the impact of construction-related deficiencies—namely, increased air voids, non-continuous gradation, and aggregate segregation. The simulation results showed that higher void content (from 4% to 10%) reduced peak load by up to 35% and increased localized stress concentrations by up to 40%. Discontinuous gradation and uneven aggregate distribution also led to premature crack initiation and more complex fracture paths. These findings demonstrated the value of micromechanical modeling for evaluating sensitivity to mix design and compaction quality, providing a foundation for performance-based asphalt mixture optimization and durability improvement. Full article

The electrocatalytic decomposition of ammonia represents a promising route for sustainable hydrogen production, yet current systems rely heavily on noble metal catalysts with prohibitive costs and limited durability. A critical challenge lies in developing non-noble electrocatalysts that simultaneously achieve high active site exposure, optimized electronic configurations, and robust structural stability. Addressing these requirements, this study strategically engineered Cu-doped ZIF-8 architectures via in situ growth on nickel foam (NF) substrates through a facile room-temperature hydrothermal synthesis approach. Systematic optimization of the Cu/Zn molar ratio revealed that Cu_0.7Zn_0.3-ZIF/NF achieved optimal performance, exhibiting a distinctive nanoflower-like architecture that substantially increased accessible active sites. The hybrid catalyst demonstrated superior electrocatalytic performance with a current density of 124 mA cm⁻² at 1.6 V vs. RHE and a notably low Tafel slope of 30.94 mV dec⁻¹, outperforming both Zn-ZIF/NF (39.45 mV dec⁻¹) and Cu-ZIF/NF (31.39 mV dec⁻¹). Combined XPS and EDS analyses unveiled a synergistic electronic structure modulation between Zn and Cu, which facilitated charge transfer and enhanced catalytic efficiency. A gas chromatography product analysis identified H₂ and N₂ as the primary gaseous products, confirming the predominant occurrence of the ammonia oxidation reaction (AOR). This study not only presents a noble metal-free electrocatalyst with exceptional efficiency and durability for ammonia decomposition but also demonstrates the significant potential of MOF-derived materials in sustainable hydrogen production technologies. Full article

Cellular senescence is a state of the durable cell cycle arrest of dysfunctional cells, which has been associated with the promotion of tumor cell reprogramming into a stem cell state. We previously reported that the mixed lineage kinase (MLK) inhibitor CEP-1347 promotes the differentiation of glioma stem cells (GSCs)—key contributors to glioblastoma recurrence and therapy resistance—into non-stem tumor cells. However, we also noted that CEP-1347–treated GSCs exhibited a morphological change suggestive of senescence. Therefore, we herein investigated whether CEP-1347 induces senescence in GSCs and, consequently, if senescent GSCs may be eliminated using senolytics. Cell death induced by CEP-1347 in combination with senolytic agents or with the knockdown of anti-apoptotic BCL2 family genes, as well as the effects of CEP-1347 on the expression of senescence markers and anti-apoptotic Bcl-2 family proteins, were examined. The results obtained showed that CEP-1347 induced senescence in GSCs accompanied by the increased expression of Bcl-xL. Among the panel of senolytic agents tested, navitoclax, a BH3 mimetic, efficiently induced cell death in GSCs when combined with CEP-1347 at concentrations clinically achievable in the brain. The knockdown of Bcl-xL resulted in more pronounced GSC death in combination with CEP-1347 than that of Bcl-2. These results suggest that combining CEP-1347 with the targeting of Bcl-xL, the expression of which increases with CEP-1347-induced senescence, is a rational approach to ensure the elimination of GSCs, thereby improving the outcomes of glioblastoma treatment. Full article

Background: Advanced and recurrent vulvar squamous cell carcinoma (VSCC) presents a major therapeutic challenge with limited treatment options and poor outcomes. Immune checkpoint inhibitors (ICIs) have shown efficacy in other HPV-associated malignancies, but their role in VSCC remains poorly defined due to the rarity of the disease and limited clinical trial data. Methods: We conducted a systematic review and meta-analysis following PRISMA guidelines and registered in PROSPERO (CRD420251067565). A comprehensive literature search identified prospective clinical trials evaluating ICIs in patients with advanced, unresectable, recurrent, or metastatic VSCC. The primary outcomes included objective response rate (ORR), progression-free survival (PFS), overall survival (OS), and safety. Risk of bias was assessed using the MINORS tool. Meta-analyses were performed using random-effects models, with subgroup analyses based on PD-L1 status and treatment regimens (monotherapy vs. combination therapy). Results: Six non-randomized single-arm trials involving 181 patients were included. The pooled ORR was 21%, with higher response rates observed in combination therapy (46%) compared to monotherapy (11%), though not statistically significant. Median PFS and OS were 2.2 months and 6.4 months, respectively. ORRs were similar between PD-L1-positive and PD-L1-negative subgroups. A safety analysis showed treatment-related adverse events (AEs) in 73% of patients and grade ≥ 3 AEs in 23%. The incidence of treatment-related death was 3%. Conclusions: ICIs demonstrate modest but durable efficacy and an acceptable safety profile in advanced VSCC. The current evidence supports their use in selected patients. However, response variability and the lack of reliable predictive biomarkers, such as PD-L1 or HPV status, underscore the need for biomarker-driven clinical trials and improved patient selection strategies. Full article

Concrete is the most important construction material, and improving its durability properties is a topic in constant development owing to the economic costs that the degradation of concrete implies. Different nanoparticles have been reported to improve concrete durability, although the positive results are not a generality. Among these nanomaterials, graphene oxide stands out as an option for improving concrete properties, such as its compressive strength, which could increase the useful life of concrete infrastructure. This study addresses the effects of graphene oxide on the durability properties of concrete, with the aim of obtaining data on the viability of graphene oxide as an additive in concrete. The incorporation of graphene oxide into concrete was carried out through graphene oxide suspensions that were incorporated into concrete mixtures with a high water/cement ratio. The characterization of concrete was done using non-destructive testing such as ultrasonic pulse velocity, electrical resistivity, porosity, capillary absorption, chloride ion permeability, and other characterization methods such as compressive strength, XPS, SEM, and EDS. Together, these tests provided an overview of the concrete durability properties that are improved, affected, or unchanged by the presence of graphene oxide. In this study, a chemical analysis was also carried out on concrete modified with graphene oxide. The results show that graphene oxide improves the compressive strength of concrete, but the effect on durability properties is negligible; however, there are indications that, in combination with other additives, improvements can be achieved, so it is advisable to continue with these studies. Full article

During a volcanic eruption, a large volume of pyroclastic material can be deposited on the roads and roofs of the urban areas near volcanoes. The use of volcanic ash as an additive for the manufacture of bricks provides a solution to the disposal of part of this natural residue and reduces the depletion of a non-renewable natural resource, clayey soil, which brings some environmental and economic advantages. The pore system, compactness, uniaxial compression strength, thermal conductivity, color and durability of bricks without and with the addition of volcanic ash were evaluated through hydric tests, mercury intrusion porosimetry, ultrasound, uniaxial compression tests, IR thermography, spectrophotometry and salt crystallization tests. The purpose of this research is to determine the feasibility of adding 10, 20 and 30% by weight of volcanic ash from La Palma (Canary Islands, Spain) in two grain sizes to produce bricks fired at 800, 950 and 1100 °C. The novelty of this study is to use two sizes of volcanic ash and fire the samples at 1100 °C, which is close to the liquidus temperature of basaltic magmas and allows a high degree of interaction between the volcanic ash and the brick matrix. The addition of fine volcanic ash was found to decrease the porosity of the bricks, although the use of high percentages of coarse volcanic ash resulted in bricks with almost the same porosity as the control samples. The volcanic ash acted as a filler, reducing the number of small pores in the bricks. The presence of vesicles in the volcanic ash reduced the compressive strength and the compactness of the bricks with additives. This reduction was more evident in bricks manufactured with 30% of coarse volcanic ash and fired at 800 and 950 °C, although they still reached the minimum resistance required for their use in construction. No significant differences in thermal conductivity were noticed between the bricks with and without volcanic ash additives, which is crucial in terms of energy savings and the construction of sustainable buildings. At 1100 °C the volcanic ash changed in color from black to red. As a result, the additive blended in better with the matrix of bricks fired at 1100 °C than in those fired at 800 and 950 °C. The bricks with and without volcanic ash and fired at 1100 °C remained intact after the salt crystallization tests. Less salt crystallized in the bricks with volcanic ash and fired at 800 and 950 °C than in the samples without additives, although their low compressive strength made them susceptible to decay. Full article

Bingdao ancient tree tea (BATT), a type of raw Pu-erh tea, is renowned for its brewing durability, characterized by a unique aroma and flavor. To explore the dynamic changes in infusion quality and the impact of multiple steeping process, BATT was brewed 14 times, and its sensory attributes, infusion color, and chemical composition were assessed across different brewing intervals. The color of the tea infusion remained relatively stable throughout the brewing process. Sensory evaluation indicated that BATT exhibited optimal sensory quality between the third and seventh infusions. While the leaching of polyphenols showed minimal variation across brews, the concentrations of ester-catechins, non-ester catechins, free amino acids, and caffeine after the seventh brewing decreased by 28.82%, 21.83%, 28.86%, and 40.37%, respectively. Our results indicated that higher concentrations of flavor compounds in the BATT infusion appeared between the fourth and seventh brews. This study provides a theoretical basis for understanding the brewing characteristics of BATT. Full article

As an emerging energy-saving approach, bio-inspired drag reduction technology has become a key research direction for reducing energy consumption and greenhouse gas emissions. This study introduces the latest research progress on bio-inspired microstructured surfaces in the field of underwater drag reduction, focusing on analyzing the drag reduction mechanism, preparation process, and application effect of the three major technological paths; namely, bio-inspired non-smooth surfaces, bio-inspired superhydrophobic surfaces, and bio-inspired modified coatings. Bio-inspired non-smooth surfaces can significantly reduce the wall shear stress by regulating the flow characteristics of the turbulent boundary layer through microstructure design. Bio-inspired superhydrophobic surfaces form stable gas–liquid interfaces through the construction of micro-nanostructures and reduce frictional resistance by utilizing the slip boundary effect. Bio-inspired modified coatings, on the other hand, realize the synergistic function of drag reduction and antifouling through targeted chemical modification of materials and design of micro-nanostructures. Although these technologies have made significant progress in drag reduction performance, their engineering applications still face bottlenecks such as manufacturing process complexity, gas layer stability, and durability. Future research should focus on the analysis of drag reduction mechanisms and optimization of material properties under multi-physical field coupling conditions, the development of efficient and low-cost manufacturing processes, and the enhancement of surface stability and adaptability through dynamic self-healing coatings and smart response materials. It is hoped that the latest research status of bio-inspired drag reduction technology reviewed in this study provides a theoretical basis and technical reference for the sustainable development and energy-saving design of ships and underwater vehicles. Full article

This study explores the use of embedded piezo sensor (EPS) employing the Electro-Mechanical Impedance (EMI) technique for real-time corrosion monitoring in reinforced E-waste concrete exposed to chloride-laden environments. With the growing environmental concerns over electronic waste (E-waste) and the demand for sustainable construction practices, printed circuit board (PCB) materials were incorporated as partial replacements for coarse aggregates in concrete. The experiment utilized M30-grade concrete mixes, substituting 15% of natural coarse aggregates with E-waste, aiming to assess both sustainability and structural performance without compromising durability. EPS configured with Lead Zirconate Titanate (PZT) patches were embedded into both conventional and E-waste concrete specimens. The EPS monitored the changes in the form of conductance and susceptance signatures across a 100–400 kHz frequency range during accelerated corrosion exposure over a 60-day period in a 3.5% NaCl solution. The corrosion progression was evaluated qualitatively through electrical impedance signatures, visually via rust formation and cracking, and quantitatively using the Root Mean Square Deviation (RMSD) of EMI signatures. The results showed that the EMI technique effectively captured the initiation and propagation stages of corrosion. E-waste concrete exhibited earlier and more severe signs of corrosion compared to conventional concrete, indicated by faster increases and subsequent declines in conductance and susceptance and higher RMSD values during the initiation phase. The EMI-based system demonstrated its capability to detect microstructural changes at early stages, making it a promising method for Structural Health Monitoring (SHM) of sustainable concretes. The study concludes that while the use of E-waste in concrete contributes positively to sustainability, it may compromise long-term durability in aggressive environments. However, the integration of EPS and EMI offers a reliable, non-destructive, and sensitive technique for real-time corrosion monitoring, supporting preventive maintenance and improved infrastructure longevity. Full article

Traditional ultra-thin asphalt wearing course designs often oversimplify wheel loads as uniform pressures, neglecting critical non-uniform effects. This study establishes a 3D finite element model incorporating realistic non-uniform tire loading to reveal its mechanistic influence on pavement responses. Results demonstrate that non-uniform loading significantly alters stress states in ultra-thin layers, substantially elevating critical stresses compared to uniform assumptions. A novel Non-uniform Load Influence Factor (NLIF) accounting for thickness effects is developed to quantify these deviations. The analysis provides a foundation for revising material strength specifications and fatigue design criteria, contributing to improved performance and durability of ultra-thin pavement systems. Full article

Aminotris(methylene phosphonic acid) (ATMP) and poly(acrylic acid) sodium salt (PAA) have shown favorable results in the treatment of porous building materials against weathering damage, showing promising potential as mixed-in additives during the production of lime-based mortars. This study investigates the impact of these additives on microstructure and mechanical properties. Additives were introduced in various concentrations to assess their influence on CaCO₃ crystallization, porosity, strength, and carbonation behavior. Results revealed significant modifications in the morphology of CaCO₃ precipitates, showing evidence of nanostructured CaCO₃ aggregates and vaterite stabilization, thus indicating a non-classical crystallization pathway through the formation of amorphous CaCO₃ phase(s), facilitated by organic occlusions. These nanostructural changes, resembling biomimetic calcitic precipitates enhanced mechanical performance by enabling plastic deformation and intergranular bridging. Increased porosity and pore connectivity facilitated CO₂ diffusion towards the mortar matrix, contributing to strength development over time. However, high additive concentrations resulted in poor mechanical performance due to the excessive air entrainment capabilities of short-length polymers. Overall, this study demonstrates that the optimized dosages of ATMP and PAA can significantly enhance the durability and mechanical performance of lime-based mortars and suggests a promising alternative for the tailored manufacturing of highly compatible and durable materials for both the restoration of cultural heritage and modern sustainable construction. Full article