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Keywords = non-AIS vessels

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10 pages, 2282 KiB  
Article
AI-Assisted Edema Map Optimization Improves Infarction Detection in Twin-Spiral Dual-Energy CT
by Ludwig Singer, Daniel Heinze, Tim Alexius Möhle, Alexander Sekita, Angelika Mennecke, Stefan Lang, Stefan T. Gerner, Stefan Schwab, Arnd Dörfler and Manuel Alexander Schmidt
Brain Sci. 2025, 15(8), 821; https://doi.org/10.3390/brainsci15080821 - 31 Jul 2025
Viewed by 269
Abstract
Objective: This study aimed to evaluate whether modifying the post-processing algorithm of Twin-Spiral Dual-Energy computed tomography (DECT) improves infarct detection compared to conventional Dual-Energy CT (DECT) and Single-Energy CT (SECT) following endovascular therapy (EVT) for large vessel occlusion (LVO). Methods: We retrospectively analyzed [...] Read more.
Objective: This study aimed to evaluate whether modifying the post-processing algorithm of Twin-Spiral Dual-Energy computed tomography (DECT) improves infarct detection compared to conventional Dual-Energy CT (DECT) and Single-Energy CT (SECT) following endovascular therapy (EVT) for large vessel occlusion (LVO). Methods: We retrospectively analyzed 52 patients who underwent Twin-Spiral DECT after endovascular stroke therapy. Ten patients were used to generate a device-specific parameter (“y”) using an AI-based neural network (SynthSR). This parameter was integrated into the post-processing algorithm for edema map generation. Quantitative Hounsfield unit (HU) measurements were used to assess density differences in ischemic brain tissue across conventional virtual non-contrast (VNC) images and edema maps. Results: The median HU of infarcted tissue in conventional mixed DECT was 33.73 ± 4.58, compared to 22.96 ± 3.81 in default VNC images. Edema maps with different smoothing filter settings showed values of 14.39 ± 4.96, 14.50 ± 3.75, and 15.05 ± 2.65, respectively. All edema maps demonstrated statistically significant HU differences of infarcted tissue compared to conventional VNC images (p<0.001) while maintaining the density values of non-infarcted brain tissue. Conclusions: Enhancing the post-processing algorithm of conventional virtual non-contrast imaging improves infarct detection compared to standard mixed or virtual non-contrast reconstructions in Dual-Energy CT. Full article
(This article belongs to the Section Neurotechnology and Neuroimaging)
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28 pages, 2918 KiB  
Article
Machine Learning-Powered KPI Framework for Real-Time, Sustainable Ship Performance Management
by Christos Spandonidis, Vasileios Iliopoulos and Iason Athanasopoulos
J. Mar. Sci. Eng. 2025, 13(8), 1440; https://doi.org/10.3390/jmse13081440 - 28 Jul 2025
Viewed by 365
Abstract
The maritime sector faces escalating demands to minimize emissions and optimize operational efficiency under tightening environmental regulations. Although technologies such as the Internet of Things (IoT), Artificial Intelligence (AI), and Digital Twins (DT) offer substantial potential, their deployment in real-time ship performance analytics [...] Read more.
The maritime sector faces escalating demands to minimize emissions and optimize operational efficiency under tightening environmental regulations. Although technologies such as the Internet of Things (IoT), Artificial Intelligence (AI), and Digital Twins (DT) offer substantial potential, their deployment in real-time ship performance analytics is at an emerging state. This paper proposes a machine learning-driven framework for real-time ship performance management. The framework starts with data collected from onboard sensors and culminates in a decision support system that is easily interpretable, even by non-experts. It also provides a method to forecast vessel performance by extrapolating Key Performance Indicator (KPI) values. Furthermore, it offers a flexible methodology for defining KPIs for every crucial component or aspect of vessel performance, illustrated through a use case focusing on fuel oil consumption. Leveraging Artificial Neural Networks (ANNs), hybrid multivariate data fusion, and high-frequency sensor streams, the system facilitates continuous diagnostics, early fault detection, and data-driven decision-making. Unlike conventional static performance models, the framework employs dynamic KPIs that evolve with the vessel’s operational state, enabling advanced trend analysis, predictive maintenance scheduling, and compliance assurance. Experimental comparison against classical KPI models highlights superior predictive fidelity, robustness, and temporal consistency. Furthermore, the paper delineates AI and ML applications across core maritime operations and introduces a scalable, modular system architecture applicable to both commercial and naval platforms. This approach bridges advanced simulation ecosystems with in situ operational data, laying a robust foundation for digital transformation and sustainability in maritime domains. Full article
(This article belongs to the Section Ocean Engineering)
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25 pages, 31775 KiB  
Article
Machine Learning-Based Binary Classification Models for Low Ice-Class Vessels Navigation Risk Assessment
by Yuanyuan Zhang, Guangyu Li, Jianfeng Zhu and Xiao Cheng
J. Mar. Sci. Eng. 2025, 13(8), 1408; https://doi.org/10.3390/jmse13081408 - 24 Jul 2025
Viewed by 255
Abstract
The presence of sea ice threatens low ice-class vessels’ navigation safety in the Arctic, and traditional Navigation Risk Assessment Models based on sea ice parameters have been widely used to guide safe passages for ships operating in ice regions. However, these models mainly [...] Read more.
The presence of sea ice threatens low ice-class vessels’ navigation safety in the Arctic, and traditional Navigation Risk Assessment Models based on sea ice parameters have been widely used to guide safe passages for ships operating in ice regions. However, these models mainly rely on empirical coefficients, and the accuracy of these models in identifying sea ice navigation risk remains insufficiently validated. Therefore, under the binary classification framework, this study used Automatic Identification System (AIS) data along the Northeast Passage (NEP) as positive samples, manual interpretation non-navigable data as negative samples, a total of 10 machine learning (ML) models were employed to capture the complex relationships between ice conditions and navigation risk for Polar Class (PC) 6 and Open Water (OW) vessels. The results showed that compared to traditional Navigation Risk Assessment Models, most of the 10 ML models exhibited significantly improved classification accuracy, which was especially pronounced when classifying samples of PC6 vessel. This study also revealed that the navigability of the East Siberian Sea (ESS) and the Vilkitsky Strait along the NEP is relatively poor, particularly during the month when sea ice melts and reforms, requiring special attention. The navigation risk output by ML models is strongly determined by sea ice thickness. These findings offer valuable insights for enhancing the safety and efficiency of Arctic maritime transport. Full article
(This article belongs to the Special Issue Remote Sensing for Maritime Monitoring and Ship Surveillance)
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14 pages, 1323 KiB  
Article
Using a Deep Learning-Based Decision Support System to Predict Emergent Large Vessel Occlusion Using Non-Contrast Computed Tomography
by Seong-Joon Lee, Dohyun Kim, Dae Han Choi, Yong Su Lim, Gyuha Park, Sumin Jung, Soohwa Song, Ji Man Hong, Dong Hoon Shin, Myeong Jin Kim and Jin Soo Lee
J. Clin. Med. 2025, 14(13), 4635; https://doi.org/10.3390/jcm14134635 - 30 Jun 2025
Viewed by 382
Abstract
Background: This retrospective, multi-reader, blinded, pivotal trial assessed the performance of artificial intelligence (AI)-based clinical decision support system used to improve the clinician detection of emergent large vessel occlusion (ELVO) using brain non-contrast computed tomography (NCCT) images. Methods: We enrolled 477 patients, of [...] Read more.
Background: This retrospective, multi-reader, blinded, pivotal trial assessed the performance of artificial intelligence (AI)-based clinical decision support system used to improve the clinician detection of emergent large vessel occlusion (ELVO) using brain non-contrast computed tomography (NCCT) images. Methods: We enrolled 477 patients, of which 112 had anterior circulation ELVO, and 365 served as controls. First, patients were evaluated by the consensus of four clinicians without AI assistance through the identification of ELVO using NCCT images. After a 2-week washout period, the same investigators performed an AI-assisted evaluation. The primary and secondary endpoints in ELVO prediction between unassisted and assisted readings were sensitivity and specificity and AUROC and individual-level sensitivity and specificity, respectively. The standalone predictive ability of the AI system was also analyzed. Results: The assisted evaluations resulted in higher sensitivity and specificity than the unassisted evaluations at 75.9% vs. 92.0% (p < 0.01) and 83.0% vs. 92.6% (p < 0.01) while also resulting in higher accuracy and AUROC at 81.3% vs. 92.5%, (p < 0.01) and 0.87 [95% CI: 0.84–0.90] vs. 0.95 [95% CI: 0.93–0.97] (p < 0.01). Furthermore, the AI system improved sensitivity and specificity for three and four readers, respectively, and had a standalone sensitivity of 88.4% (95% CI: 81.0–93.7) and a specificity of 91.2% (95% CI: 87.9–93.9). Conclusions: This study shows that an AI-based clinical decision support system can improve the clinical detection of ELVO using NCCT. Moreover, the AI system may facilitate acute stroke reperfusion therapy by assisting physicians in the initial triaging of patients, particularly in thrombectomy-incapable centers. Full article
(This article belongs to the Section Clinical Neurology)
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20 pages, 1780 KiB  
Article
Tracking Tourism Waves: Insights from Automatic Identification System (AIS) Data on Maritime–Coastal Activities
by Jorge Ramos, Benjamin Drakeford, Joana Costa, Ana Madiedo and Francisco Leitão
Tour. Hosp. 2025, 6(2), 99; https://doi.org/10.3390/tourhosp6020099 - 31 May 2025
Viewed by 590
Abstract
The demand for maritime–coastal tourism has been intensifying, but its offerings are sometimes limited to a few activities. Some of these activities do not require specific skills or certifications, while others do. This study aimed to investigate what type of activities are carried [...] Read more.
The demand for maritime–coastal tourism has been intensifying, but its offerings are sometimes limited to a few activities. Some of these activities do not require specific skills or certifications, while others do. This study aimed to investigate what type of activities are carried out by tourism and recreational vessels in the coastal area of the central Algarve (Portugal). To this end, data from the automatic identification system (AIS) of recreational vessels was used to monitor and categorise these activities in a non-intrusive manner. A model (TORMA) was defined to facilitate the analysis of AIS data and relate them to five independent variables (distance from the coast, boat speed, bathymetry, seabed type, and number of pings). The results of the analysis of more than 11 thousand hourly AIS records for passenger, sailing, and charter vessels showed that the 14 most regular ones had strong seasonal patterns, greater intensity in summer, and spatial patterns with more records near some coastal cliffs. This study provides valuable information on the management of motorised nautical activities near the coast and at sea, contributing to more informed and effective tourism regulation and planning. Full article
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48 pages, 1063 KiB  
Review
Point-of-Care Electroencephalography in Acute Neurological Care: A Narrative Review
by Roberto Fratangelo, Francesco Lolli, Maenia Scarpino and Antonello Grippo
Neurol. Int. 2025, 17(4), 48; https://doi.org/10.3390/neurolint17040048 - 24 Mar 2025
Viewed by 1107
Abstract
Point-of-care electroencephalography (POC-EEG) systems are rapid-access, reduced-montage devices designed to address the limitations of conventional EEG (conv-EEG), enabling faster neurophysiological assessment in acute settings. This review evaluates their clinical impact, diagnostic performance, and feasibility in non-convulsive status epilepticus (NCSE), traumatic brain injury (TBI), [...] Read more.
Point-of-care electroencephalography (POC-EEG) systems are rapid-access, reduced-montage devices designed to address the limitations of conventional EEG (conv-EEG), enabling faster neurophysiological assessment in acute settings. This review evaluates their clinical impact, diagnostic performance, and feasibility in non-convulsive status epilepticus (NCSE), traumatic brain injury (TBI), stroke, and delirium. A comprehensive search of Medline, Scopus, and Embase identified 69 studies assessing 15 devices. In suspected NCSE, POC-EEG facilitates rapid seizure detection and prompt diagnosis, making it particularly effective in time-sensitive and resource-limited settings. Its after-hours availability and telemedicine integration ensure continuous coverage. AI-assisted tools enhance interpretability and accessibility, enabling use by non-experts. Despite variability in accuracy, it supports triaging, improving management, treatment decisions and outcomes while reducing hospital stays, transfers, and costs. In TBI, POC-EEG-derived quantitative EEG (qEEG) indices reliably detect structural lesions, support triage, and minimize unnecessary CT scans. They also help assess concussion severity and predict recovery. For strokes, POC-EEG aids triage by detecting large vessel occlusions (LVOs) with high feasibility in hospital and prehospital settings. In delirium, spectral analysis and AI-assisted models enhance diagnostic accuracy, broadening its clinical applications. Although POC-EEG is a promising screening tool, challenges remain in diagnostic variability, technical limitations, and AI optimization, requiring further research. Full article
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31 pages, 3860 KiB  
Article
Machine Learning-Driven Prediction of Offshore Vessel Detention: The Role of Neural Networks in Port State Control
by Zlatko Boko, Tatjana Stanivuk, Nenad Radanović and Ivica Skoko
J. Mar. Sci. Eng. 2025, 13(3), 472; https://doi.org/10.3390/jmse13030472 - 28 Feb 2025
Cited by 2 | Viewed by 690
Abstract
This study investigates the application of different neural network (NN) models in assessing the risk of the detention of offshore vessels during port state control (PSC) inspections. The focus is on the use of different NN models (“nnet”, “mlp”, “neuralnet”, “rsnns”) to identify [...] Read more.
This study investigates the application of different neural network (NN) models in assessing the risk of the detention of offshore vessels during port state control (PSC) inspections. The focus is on the use of different NN models (“nnet”, “mlp”, “neuralnet”, “rsnns”) to identify the main risk factors based on historical data on vessels and their inspections. The main objective of this research is to improve maritime safety and the efficiency of inspection procedures by applying techniques that can more accurately predict the probability of detention of the offshore vessels. These models make it possible to analyse complex patterns in the data, such as the relationships between the country of inspection, flag, memorandum, age, tonnage and previous deficiencies, and the risk of detention. Understanding these patterns is crucial for inspection teams’ proactive action as it helps direct resources to potentially high-risk vessels. Implementing these models into PSC processes helps to optimise resource allocation, reduce unnecessary costs, and increase the reliability of decision-making processes. NN models significantly help in recognising non-linear patterns and provide high accuracy in risk prediction. The study also includes a comparative analysis of the elements that determine the accuracy, sensitivity, and other performance aspects of the models to determine the most appropriate approach for practical implementation. The results emphasise the importance of applying artificial intelligence (AI) in various aspects of modern maritime safety management. This research opens up new opportunities for the development of intelligent support systems that not only increase safety but also improve the efficiency of inspection processes on a global scale. Full article
(This article belongs to the Special Issue Advances in the Performance of Ships and Offshore Structures)
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26 pages, 17412 KiB  
Article
Enhancing Maritime Safety: Estimating Collision Probabilities with Trajectory Prediction Boundaries Using Deep Learning Models
by Robertas Jurkus, Julius Venskus, Jurgita Markevičiūtė and Povilas Treigys
Sensors 2025, 25(5), 1365; https://doi.org/10.3390/s25051365 - 23 Feb 2025
Viewed by 845
Abstract
We investigate maritime accidents near Bornholm Island in the Baltic Sea, focusing on one of the most recent vessel collisions and a way to improve maritime safety as a prevention strategy. By leveraging Long Short-Term Memory autoencoders, a class of deep recurrent neural [...] Read more.
We investigate maritime accidents near Bornholm Island in the Baltic Sea, focusing on one of the most recent vessel collisions and a way to improve maritime safety as a prevention strategy. By leveraging Long Short-Term Memory autoencoders, a class of deep recurrent neural networks, this research demonstrates a unique approach to forecasting vessel trajectories and assessing collision risks. The proposed method integrates trajectory predictions with statistical techniques to construct probabilistic boundaries, including confidence intervals, prediction intervals, ellipsoidal prediction regions, and conformal prediction regions. The study introduces a collision risk score, which evaluates the likelihood of boundary overlaps as a metric for collision detection. These methods are applied to simulated test scenarios and a real-world case study involving the 2021 collision between the Scot Carrier and Karin Hoej cargo ships. The results demonstrate that CPR, a non-parametric approach, reliably forecasts collision risks with 95% confidence. The findings underscore the importance of integrating statistical uncertainty quantification with deep learning models to improve navigational decision-making and encourage a shift towards more proactive, AI/ML-enhanced maritime risk management protocols. Full article
(This article belongs to the Section Intelligent Sensors)
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17 pages, 2634 KiB  
Article
Non-Contrast Computed Tomography-Based Triage and Notification for Large Vessel Occlusion Stroke: A Before and After Study Utilizing Artificial Intelligence on Treatment Times and Outcomes
by Yong Su Lim, Eunji Kim, Woo Sung Choi, Hyuk Jun Yang, Jong Youn Moon, Jae Ho Jang, Jinseong Cho, Jeayeon Choi and Jae-Hyug Woo
J. Clin. Med. 2025, 14(4), 1281; https://doi.org/10.3390/jcm14041281 - 15 Feb 2025
Cited by 1 | Viewed by 1150
Abstract
Background/Objectives: The clinical impact of automated large vessel occlusion (LVO) detection tools using non-contrast CT (NCCT) is still unknown. We evaluated whether the implementation of Heuron ELVO, an artificial intelligence (AI)-driven software for triage and notification of LVO stroke using NCCT, can [...] Read more.
Background/Objectives: The clinical impact of automated large vessel occlusion (LVO) detection tools using non-contrast CT (NCCT) is still unknown. We evaluated whether the implementation of Heuron ELVO, an artificial intelligence (AI)-driven software for triage and notification of LVO stroke using NCCT, can reduce treatment times and improve clinical outcomes in a real-world setting. Methods: We compared patients with LVO stroke before (pre-AI cohort, 84 patients) and after (post-AI cohort, 48 patients) the implementation of Heuron ELVO at a comprehensive stroke center. Primary outcomes included time-to-treatment initiation, including door-to-IV tPA and door-to-endovascular thrombectomy (EVT) times. Secondary outcomes measured changes in the National Institute of Health Stroke Scale (NIHSS) and modified Rankin Scale (mRS) scores. Statistical analyses involved multiple linear regression to adjust for confounders. Results: The implementation of Heuron ELVO significantly reduced the door-to-EVT time (30.2 min, 95% CI, −56. to −4.3), CT-to-neurologist examination time (16.4 min, 95% CI, −27.6 to −5.3), and CT-to-EVT time (29.4 min, 95% CI, −53.6 to −5.0). There was no statistical difference in the door-to-IV tPA time (8.9 min). The post-AI cohort exhibited a greater improvement in the NIHSS score compared to the pre-AI cohort, with a reduction of 4.3 points. While the post-AI cohort demonstrated a higher proportion of good outcomes (mRS 0–1, 26% vs. 40%) at the 3-month follow-up, there was no statistical significance. Conclusions: The implementation of Heuron ELVO demonstrated substantial improvements in the timeliness of stroke interventions and patient outcomes. These findings underscore the potential of AI-driven NCCT analysis in enhancing acute stroke workflows and expediting treatments in real-world settings. Full article
(This article belongs to the Section Emergency Medicine)
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26 pages, 3066 KiB  
Article
Advancing Marine Surveillance: A Hybrid Approach of Physics Infused Neural Network for Enhanced Vessel Tracking Using Automatic Identification System Data
by Tasmiah Haque, Md Asif Bin Syed, Srinjoy Das and Imtiaz Ahmed
J. Mar. Sci. Eng. 2024, 12(11), 1913; https://doi.org/10.3390/jmse12111913 - 26 Oct 2024
Viewed by 1417
Abstract
In the domain of maritime surveillance, the continuous tracking and monitoring of vessels are imperative for the early detection of potential threats. The Automatic Identification System (AIS) database, which collects vessel movement data over time, including timestamps and other motion details, plays a [...] Read more.
In the domain of maritime surveillance, the continuous tracking and monitoring of vessels are imperative for the early detection of potential threats. The Automatic Identification System (AIS) database, which collects vessel movement data over time, including timestamps and other motion details, plays a crucial role in real-time maritime monitoring. However, it frequently exhibits irregular intervals of data collection and intricate, intersecting trajectories, underscoring the importance of analyzing long-term temporal patterns for effective vessel tracking. While Kalman Filters and other physics-based models have been employed to tackle these issues, their effectiveness is limited by their inability to capture long-term dependence and non-linearity in the historical data. This paper introduces a novel approach that leverages Long Short-Term Memory (LSTM), a type of recurrent neural network, renowned for its proficiency in recognizing patterns over extended periods. Recognizing the strengths and limitations of the LSTM model, we propose a hybrid machine-learning algorithm that integrates LSTM with a physics-based model. This combination harnesses the physical laws governing vessel movements alongside data driven pattern mining, thereby enhancing the predictive accuracy of vessel locations. To assess the performance of standalone and hybrid models, various scenarios with different levels of complexity are generated. Furthermore, to simulate real-world data loss conditions often encountered in maritime tracking, temporal data gaps are randomly introduced into the scenarios. The competing approaches are then evaluated using both with time gap and without time gap conditions. Our results show that, although the LSTM model performs better than the physics-based model, the hybrid model consistently outperforms both standalone models across all scenarios. Furthermore, while data gaps negatively impact the accuracy of all models, the performance reduction is minimal for the physics-infused model. In summary, this study not only demonstrates the potential of combining data-driven and physics-based approaches but also sets a new benchmark for maritime vessel tracking. Full article
(This article belongs to the Section Ocean Engineering)
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24 pages, 12319 KiB  
Article
Anchor Dragging Risk Estimation Strategy from Supervised Cost-Sensitive Learning
by Sang-Lok Yoo, Shem Otoi Onyango, Joo-Sung Kim and Kwang-Il Kim
J. Mar. Sci. Eng. 2024, 12(10), 1817; https://doi.org/10.3390/jmse12101817 - 12 Oct 2024
Viewed by 1698
Abstract
Anchor dragging at anchorages poses a significant threat to marine traffic, potentially leading to collisions and damage to seabed infrastructure. This study analyzed a large dataset of ships in anchorage areas to develop a machine learning (ML) model that estimates the risk of [...] Read more.
Anchor dragging at anchorages poses a significant threat to marine traffic, potentially leading to collisions and damage to seabed infrastructure. This study analyzed a large dataset of ships in anchorage areas to develop a machine learning (ML) model that estimates the risk of anchor dragging using a binary classification system that differentiates between dragging and non-dragging incidents. Historical data from the automatic identification system (AIS), hydrographic, and meteorological sources were compiled for each case. Preliminary analysis revealed a significant class imbalance, with non-dragging cases far outnumbering dragging cases. This suggested that the optimal ML strategy would involve undersampling the majority class and cost-sensitive learning. A combination of data-undersampling methods and cost-sensitive algorithms was used to select the model with the best recall, area under the receiver operating characteristic curve (AUC), and geometric mean (GM) scores. The neighborhood cleaning rule undersampler paired with cost-sensitive logistic regression outperformed other models, achieving recall, GM, and AUC scores of 0.889, 0.767, and 0.810, respectively. This study also demonstrated potential applications of the model, discussed its limitations, and suggested possible improvements for the ML approach. Our method advances maritime safety by enabling the intelligent, risk-aware monitoring of anchored vessels through machine learning, enhancing the capabilities of vessel traffic service officers. Full article
(This article belongs to the Special Issue Risk Assessment in Maritime Transportation)
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29 pages, 2184 KiB  
Review
A Systematic Review of Ship Wake Detection Methods in Satellite Imagery
by Andrea Mazzeo, Alfredo Renga and Maria Daniela Graziano
Remote Sens. 2024, 16(20), 3775; https://doi.org/10.3390/rs16203775 - 11 Oct 2024
Cited by 2 | Viewed by 4260
Abstract
The field of maritime surveillance is one of great strategical importance from the point of view of both civil and military applications. The growing availability of spaceborne imagery makes it a great tool for ship detection, especially when paired with information from the [...] Read more.
The field of maritime surveillance is one of great strategical importance from the point of view of both civil and military applications. The growing availability of spaceborne imagery makes it a great tool for ship detection, especially when paired with information from the automatic identification system (AIS). However, small vessels can be challenging targets for spaceborne sensors without relatively high resolution. Moreover, when faced with non-cooperative targets, hull detection alone is insufficient for obtaining critical information like target speed and heading. The wakes generated by the movement of ships can be used to solve both of these issues. Several interesting solutions have been developed over the years, based on both traditional and learning-based methodologies. This review aims to provide the first thorough overview of ship wake detection solutions, highlighting the key ideas behind traditional applications, then covering more innovative applications based on deep learning (DL), to serve as a solid starting point for present and future researchers interested in the field. Full article
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21 pages, 883 KiB  
Review
Retinal Imaging-Based Oculomics: Artificial Intelligence as a Tool in the Diagnosis of Cardiovascular and Metabolic Diseases
by Laura Andreea Ghenciu, Mirabela Dima, Emil Robert Stoicescu, Roxana Iacob, Casiana Boru and Ovidiu Alin Hațegan
Biomedicines 2024, 12(9), 2150; https://doi.org/10.3390/biomedicines12092150 - 23 Sep 2024
Cited by 15 | Viewed by 5326
Abstract
Cardiovascular diseases (CVDs) are a major cause of mortality globally, emphasizing the need for early detection and effective risk assessment to improve patient outcomes. Advances in oculomics, which utilize the relationship between retinal microvascular changes and systemic vascular health, offer a promising non-invasive [...] Read more.
Cardiovascular diseases (CVDs) are a major cause of mortality globally, emphasizing the need for early detection and effective risk assessment to improve patient outcomes. Advances in oculomics, which utilize the relationship between retinal microvascular changes and systemic vascular health, offer a promising non-invasive approach to assessing CVD risk. Retinal fundus imaging and optical coherence tomography/angiography (OCT/OCTA) provides critical information for early diagnosis, with retinal vascular parameters such as vessel caliber, tortuosity, and branching patterns identified as key biomarkers. Given the large volume of data generated during routine eye exams, there is a growing need for automated tools to aid in diagnosis and risk prediction. The study demonstrates that AI-driven analysis of retinal images can accurately predict cardiovascular risk factors, cardiovascular events, and metabolic diseases, surpassing traditional diagnostic methods in some cases. These models achieved area under the curve (AUC) values ranging from 0.71 to 0.87, sensitivity between 71% and 89%, and specificity between 40% and 70%, surpassing traditional diagnostic methods in some cases. This approach highlights the potential of retinal imaging as a key component in personalized medicine, enabling more precise risk assessment and earlier intervention. It not only aids in detecting vascular abnormalities that may precede cardiovascular events but also offers a scalable, non-invasive, and cost-effective solution for widespread screening. However, the article also emphasizes the need for further research to standardize imaging protocols and validate the clinical utility of these biomarkers across different populations. By integrating oculomics into routine clinical practice, healthcare providers could significantly enhance early detection and management of systemic diseases, ultimately improving patient outcomes. Fundus image analysis thus represents a valuable tool in the future of precision medicine and cardiovascular health management. Full article
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13 pages, 3854 KiB  
Review
The Role of Coronary Imaging in Chronic Total Occlusions: Applications and Future Possibilities
by Giuseppe Panuccio, Youssef S. Abdelwahed, Nicole Carabetta, Ulf Landmesser, Salvatore De Rosa and Daniele Torella
J. Cardiovasc. Dev. Dis. 2024, 11(9), 295; https://doi.org/10.3390/jcdd11090295 - 21 Sep 2024
Cited by 2 | Viewed by 2329
Abstract
Chronic total occlusions (CTOs) represent a challenging scenario in coronary artery disease (CAD). The prevalence of CTOS in patients undergoing coronary angiography underscores the need for effective diagnostic and therapeutic strategies. Coronary angiography, while essential, offers limited insights into lesion morphology, vessel course, [...] Read more.
Chronic total occlusions (CTOs) represent a challenging scenario in coronary artery disease (CAD). The prevalence of CTOS in patients undergoing coronary angiography underscores the need for effective diagnostic and therapeutic strategies. Coronary angiography, while essential, offers limited insights into lesion morphology, vessel course, and myocardial viability. In contrast, coronary imaging techniques—including optical coherence tomography (OCT), intravascular ultrasound (IVUS), and coronary computed tomography angiography (CCTA)—provide comprehensive insights for each stage of CTO percutaneous coronary intervention (PCI). OCT facilitates the assessment of plaque morphology and stent optimization, despite low evidence and several limitations in CTO-PCI. IVUS offers deeper penetration, allowing managing proximal cap scenarios and guiding subintimal navigation. CCTA provides a non-invasive, three-dimensional view of coronary anatomy, enabling the precise evaluation of myocardial mass at risk and detailed procedural planning. Despite their individual limitations, these imaging modalities have enhanced the success rates of CTO-PCI, thus reducing procedural and long-term complications and improving patient outcomes. The future of CTO management lies in further technological advancements, including hybrid imaging, artificial intelligence (AI) integration, and improved fusion imaging. These innovations promise to refine procedural precision and personalize interventions, ultimately improving the care of patients with complex coronary artery disease. Full article
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18 pages, 967 KiB  
Review
Non-Invasive Retinal Vessel Analysis as a Predictor for Cardiovascular Disease
by Raluca Eugenia Iorga, Damiana Costin, Răzvana Sorina Munteanu-Dănulescu, Elena Rezuș and Andreea Dana Moraru
J. Pers. Med. 2024, 14(5), 501; https://doi.org/10.3390/jpm14050501 - 9 May 2024
Cited by 9 | Viewed by 3257
Abstract
Cardiovascular disease (CVD) is the most frequent cause of death worldwide. The alterations in the microcirculation may predict the cardiovascular mortality. The retinal vasculature can be used as a model to study vascular alterations associated with cardiovascular disease. In order to quantify microvascular [...] Read more.
Cardiovascular disease (CVD) is the most frequent cause of death worldwide. The alterations in the microcirculation may predict the cardiovascular mortality. The retinal vasculature can be used as a model to study vascular alterations associated with cardiovascular disease. In order to quantify microvascular changes in a non-invasive way, fundus images can be taken and analysed. The central retinal arteriolar (CRAE), the venular (CRVE) diameter and the arteriolar-to-venular diameter ratio (AVR) can be used as biomarkers to predict the cardiovascular mortality. A narrower CRAE, wider CRVE and a lower AVR have been associated with increased cardiovascular events. Dynamic retinal vessel analysis (DRVA) allows the quantification of retinal changes using digital image sequences in response to visual stimulation with flicker light. This article is not just a review of the current literature, it also aims to discuss the methodological benefits and to identify research gaps. It highlights the potential use of microvascular biomarkers for screening and treatment monitoring of cardiovascular disease. Artificial intelligence (AI), such as Quantitative Analysis of Retinal vessel Topology and size (QUARTZ), and SIVA–deep learning system (SIVA-DLS), seems efficient in extracting information from fundus photographs and has the advantage of increasing diagnosis accuracy and improving patient care by complementing the role of physicians. Retinal vascular imaging using AI may help identify the cardiovascular risk, and is an important tool in primary cardiovascular disease prevention. Further research should explore the potential clinical application of retinal microvascular biomarkers, in order to assess systemic vascular health status, and to predict cardiovascular events. Full article
(This article belongs to the Special Issue New Advances in Diagnostic and Surgical Treatment of Ocular Diseases)
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