Search Results (1,322)

Non-invasive ultrasound diagnosis, combined with deep learning, is frequently used for detecting thyroid diseases. However, real-time detection on portable devices faces limitations due to constrained computational resources, and existing models often lack sufficient capability for small object detection of thyroid nodules. To address this, this paper proposes an improved lightweight small object detection network framework called LISA-YOLO, which enhances the lightweight multi-scale collaborative fusion algorithm. The proposed framework exploits the inherent symmetrical characteristics of ultrasound images and the symmetrical architecture of the detection network to better capture and represent features of thyroid nodules. Specifically, an improved depthwise separable convolution algorithm replaces traditional convolution to construct a lightweight network (DG-FNet). Through symmetrical cross-scale fusion operations via FPN, detection accuracy is maintained while reducing computational overhead. Additionally, an improved bidirectional feature network (IMS F-NET) fully integrates the semantic and detailed information of high- and low-level features symmetrically, enhancing the representation capability for multi-scale features and improving the accuracy of small object detection. Finally, a collaborative attention mechanism (SAF-NET) uses a dual-channel and spatial attention mechanism to adaptively calibrate channel and spatial weights in a symmetric manner, effectively suppressing background noise and enabling the model to focus on small target areas in thyroid ultrasound images. Extensive experiments on two image datasets demonstrate that the proposed method achieves improvements of 2.3% in F1 score, 4.5% in mAP, and 9.0% in FPS, while maintaining only 2.6 M parameters and reducing GFLOPs from 6.1 to 5.8. The proposed framework provides significant advancements in lightweight real-time detection and demonstrates the important role of symmetry in enhancing the performance of ultrasound-based thyroid diagnosis. Full article

Cell confluence and number are critical indicators for assessing cellular growth status, contributing to disease diagnosis and the development of targeted therapies. Accurate and efficient cell segmentation is essential for quantifying these indicators. However, current segmentation methodologies still encounter significant challenges in addressing multi-scale heterogeneity, poorly delineated boundaries under limited annotation, and the inherent trade-off between computational efficiency and segmentation accuracy. We propose an innovative network architecture. First, a preprocessing pipeline combining contrast-limited adaptive histogram equalization (CLAHE) and Gaussian blur is introduced to balance noise suppression and local contrast enhancement. Second, a bidirectional feature pyramid network (BiFPN) is incorporated, leveraging cross-scale feature calibration to enhance multi-scale cell recognition. Third, adaptive kernel convolution (AKConv) is developed to capture the heterogeneous spatial distribution of glioma stem cells (GSCs) through dynamic kernel deformation, improving boundary segmentation while reducing model complexity. Finally, a probability density-guided non-maximum suppression (Soft-NMS) algorithm is proposed to alleviate cell under-detection. Experimental results demonstrate that the model achieves 95.7% mAP50 (box) and 95% mAP50 (mask) on the GSCs dataset with an inference speed of 38 frames per second. Moreover, it simultaneously supports dual-modality output for cell confluence assessment and precise counting, providing a reliable automated tool for tumor microenvironment research. Full article

In recent years, deep learning methods have made breakthroughs in the field of rotating equipment fault diagnosis, thanks to their powerful data analysis capabilities. However, the vibration signals usually incorporate fault features and background noise, and these features may be scattered over multiple frequency levels, which increases the complexity of extracting important information from them. To address this problem, this paper proposes a Masked and Cascaded Multi-Branch Attention Network (MCMBAN), which combines the Noise Mask Filter Block (NMFB) with the Multi-Branch Cascade Attention Block (MBCAB), and significantly improves the noise immunity of the fault diagnostic model and the efficiency of fault feature extraction. NMFB novelly combines a wide convolutional layer and a top k neighbor self-attention masking mechanism, so as to efficiently filter unnecessary high-frequency noise in the vibration signal. On the other hand, MBCAB strengthens the interaction between different layers by cascading the convolutional layers of different scales, thus improving the recognition of periodic fault signals and greatly enhancing the diagnosis accuracy of the model when processing complex signals. Finally, the time–frequency analysis technique is employed to explore the internal mechanisms of the model in depth, aiming to validate the effectiveness of NMFB and MBCAB in fault feature recognition and to improve the feature interpretability of the proposed modes in fault diagnosis applications. We validate the superior performance of the network model in dealing with high-noise backgrounds by testing it on a standard bearing dataset from Case Western Reserve University and a self-constructed composite bearing fault dataset, and the experimental results show that its performance exceeded six of the top current fault diagnosis techniques. Full article

Rotating compressors are foundational in various industrial processes, particularly in the oil-and-gas sector, where reliable fault detection is crucial for maintaining operational continuity. While Graph Attention Network (GAT) frameworks are widely available, this study advances the state of the art by introducing a Bayesian GAT method specifically tailored for vibration-based compressor fault diagnosis. The approach integrates domain-specific digital-twin simulations built with Rotordynamic software (1.3.0), and constructs dual adjacency matrices to encode both physically informed and data-driven sensor relationships. Additionally, a hybrid forecasting-and-reconstruction objective enables the model to capture short-term deviations as well as long-term waveform fidelity. Monte Carlo dropout further decomposes prediction uncertainty into aleatoric and epistemic components, providing a more robust and interpretable model. Comparative evaluations against conventional Long Short-Term Memory (LSTM)-based autoencoder and forecasting methods demonstrate that the proposed framework achieves superior fault-detection performance across multiple fault types, including misalignment, bearing failure, and unbalance. Moreover, uncertainty analyses confirm that fault severity correlates with increasing levels of both aleatoric and epistemic uncertainty, reflecting heightened noise and reduced model confidence under more severe conditions. By enhancing GAT fundamentals with a domain-tailored dual-graph strategy, specialized Bayesian inference, and digital-twin data generation, this research delivers a comprehensive and interpretable solution for compressor fault diagnosis, paving the way for more reliable and risk-aware predictive maintenance in complex rotating machinery. Full article

Multi-organ medical image segmentation is essential for accurate clinical diagnosis, effective treatment planning, and reliable prognosis, yet it remains challenging due to complex backgrounds, irrelevant noise, unclear organ boundaries, and wide variations in organ size. To address these challenges, the boundary feature learning and enhancement network is proposed. This model integrates a dedicated boundary learning module combined with an auxiliary loss function to strengthen the semantic correlations between boundary pixels and regional features, thus reducing category mis-segmentation. Additionally, channel and positional compound attention mechanisms are employed to selectively filter features and minimize background interference. To further enhance multi-scale representation capabilities, the dynamic scale-aware context module dynamically selects and fuses multi-scale features, significantly improving the model’s adaptability. The model achieves average Dice similarity coefficients of 81.67% on synapse and 90.55% on ACDC datasets, outperforming state-of-the-art methods. This network significantly improves segmentation by emphasizing boundary accuracy, noise reduction, and multi-scale adaptability, enhancing clinical diagnostics and treatment planning. Full article

Accurate segmentation of cardiac MR images using deep neural networks is crucial for cardiac disease diagnosis and treatment planning, as it provides quantitative insights into heart anatomy and function. However, achieving high segmentation accuracy relies heavily on extensive, precisely annotated datasets, which are costly and time-consuming to obtain. This study addresses this challenge by proposing a novel data augmentation framework based on a condition-guided diffusion generative model, controlled by multiple cardiac labels. The framework aims to expand annotated cardiac MR datasets and significantly improve the performance of downstream cardiac segmentation tasks. The proposed generative data augmentation framework operates in two stages. First, a Label Diffusion Module is trained to unconditionally generate realistic multi-category spatial masks (encompassing regions such as the left ventricle, interventricular septum, and right ventricle) conforming to anatomical prior probabilities derived from noise. Second, cardiac MR images are generated conditioned on these semantic masks, ensuring a precise one-to-one mapping between synthetic labels and images through the integration of a spatially-adaptive normalization (SPADE) module for structural constraint during conditional model training. The effectiveness of this augmentation strategy is demonstrated using the U-Net model for segmentation on the enhanced 2D cardiac image dataset derived from the M&M Challenge. Results indicate that the proposed method effectively increases dataset sample numbers and significantly improves cardiac segmentation accuracy, achieving a 5% to 10% higher Dice Similarity Coefficient (DSC) compared to traditional data augmentation methods. Experiments further reveal a strong correlation between image generation quality and augmentation effectiveness. This framework offers a robust solution for data scarcity in cardiac image analysis, directly benefiting clinical applications. Full article

Biomarkers play a pivotal role in disease diagnosis, therapeutic efficacy evaluation, prognostic assessment, and drug screening. However, the trace concentrations of these markers in complex physiological environments pose significant challenges to efficient detection. It is necessary to avoid interference from non-specific signals, which may lead to misjudgment of other substances as biomarkers and affect the accuracy of detection results. With the rapid advancements in electrochemical technologies and artificial intelligence (AI) algorithms, intelligent electrochemical biosensors have emerged as a promising approach for biomedical detection, offering speed, specificity, high sensitivity, and accuracy. This review focuses on elaborating the latest applications of AI-empowered electrochemical biosensors in the biomedical field, including disease diagnosis, treatment monitoring, drug development, and wearable devices. AI algorithms can further improve the accuracy, sensitivity, and repeatability of electrochemical sensors through the screening and performance prediction of sensor materials, as well as the feature extraction and noise reduction suppression of sensing signals. Even in complex physiological microenvironments, they can effectively address common issues such as electrode fouling, poor signal-to-noise ratio, chemical interference, and matrix effects. This work may provide novel insights for the development of next-generation intelligent biosensors for precision medicine. Full article

Accurate segmentation in medical imaging is essential for disease diagnosis and monitoring, particularly in lung imaging using proton and hyperpolarized gas MRI. However, image degradation due to noise and artifacts—especially in hyperpolarized gas MRI, where scans are acquired during breath-holds—poses challenges for conventional segmentation algorithms. This study evaluates the robustness of deep learning segmentation models under varying Gaussian noise levels, comparing traditional convolutional neural networks (CNNs) with modern Vision Transformer (ViT)-based models. Using a dataset of proton and hyperpolarized gas MRI slices from 56 participants, we trained and tested Feature Pyramid Network (FPN) and U-Net architectures with both CNN (VGG16, VGG19, ResNet152) and ViT (MiT-B0, B3, B5) backbones. Results showed that ViT-based models, particularly those using the SegFormer backbone, consistently outperformed CNN-based counterparts across all metrics and noise levels. The performance gap was especially pronounced in high-noise conditions, where transformer models retained higher Dice scores and lower boundary errors. These findings highlight the potential of ViT-based architectures for deployment in clinically realistic, low-SNR environments such as hyperpolarized gas MRI, where segmentation reliability is critical. Full article

Segmentation of skin lesions in dermoscopic images is critical for the accurate diagnosis of skin cancers, particularly malignant melanoma, yet it is hindered by irregular lesion shapes, blurred boundaries, low contrast, and artifacts, such as hair interference. Conventional deep learning methods, typically based on UNet or Transformer architectures, often face limitations in regard to fully exploiting lesion features and incur high computational costs, compromising precise lesion delineation. To overcome these challenges, we propose SGNet, a structure-guided network, integrating a hybrid CNN–Mamba framework for robust skin lesion segmentation. The SGNet employs the Visual Mamba (VMamba) encoder to efficiently extract multi-scale features, followed by the Dual-Domain Boundary Enhancer (DDBE), which refines boundary representations and suppresses noise through spatial and frequency-domain processing. The Semantic-Texture Fusion Unit (STFU) adaptively integrates low-level texture with high-level semantic features, while the Structure-Aware Guidance Module (SAGM) generates coarse segmentation maps to provide global structural guidance. The Guided Multi-Scale Refiner (GMSR) further optimizes boundary details through a multi-scale semantic attention mechanism. Comprehensive experiments based on the ISIC2017, ISIC2018, and PH2 datasets demonstrate SGNet’s superior performance, with average improvements of 3.30% in terms of the mean Intersection over Union (mIoU) value and 1.77% in regard to the Dice Similarity Coefficient (DSC) compared to state-of-the-art methods. Ablation studies confirm the effectiveness of each component, highlighting SGNet’s exceptional accuracy and robust generalization for computer-aided dermatological diagnosis. Full article

Rolling bearings serve as the most widely utilized general components in drive systems for rotating machinery, and they are susceptible to regular malfunctions. To address the performance degradation encountered by current convolutional neural network-based rolling-bearing-fault diagnosis methods due to significant noise interference and variable working conditions in industrial settings, we propose a rolling-bearing-fault diagnosis method based on dual multi-scale mechanism applicable to noisy-variable operating conditions. The suggested approach begins with the implementation of Variational Mode Decomposition (VMD) on the initial vibration signal. This is succeeded by a denoising process that utilizes the goodness-of-fit test based on the Anderson–Darling (AD) distance for enhanced accuracy. This approach targets the intrinsic mode functions (IMFs), which capture information across multiple scales, to obtain the most precise denoised signal possible. Subsequently, we introduce the Dynamic Weighted Multi-Scale Feature Convolutional Neural Network (DWMFCNN) model, which integrates two structures: multi-scale feature extraction and dynamic weighting of these features. Ultimately, the signal that has been denoised is utilized as input for the DWMFCNN model to recognize different kinds of rolling-bearing faults. Results from the experiments show that the suggested approach shows an improved denoising performance and a greater adaptability to changing working conditions. Full article

The inter-shaft bearing is an important component of aero-engine rotor systems. It works between a high-pressure rotor and a low-pressure rotor. Effective fault diagnosis of it is significant for an aero-engine. The casing vibration signals can promptly and intuitively reflect changes in the operational health status of an aero-engine’s support system. However, affected by a complex vibration transmission path and vibration of the dual-rotor, the intrinsic vibration information of the inter-shaft bearing is faced with strong noise and a dual-frequency excitation problem. This excitation is caused by the wide span of vibration source frequency distribution that results from the quite different rotational speeds of the high-pressure rotor and low-pressure rotor. Consequently, most existing fault diagnosis methods cannot effectively extract inter-shaft bearing characteristic frequency information from the casing signal. To solve this problem, this paper proposed the denoised improved envelope spectrum (DIES) method. First, an improved envelope spectrum generated by a spectrum subtraction method is proposed. This method is applied to solve the multi-source interference with wide-band distribution problem under dual-frequency excitation. Then, an improved adaptive-thresholding approach is subsequently applied to the resultant subtracted spectrum, so as to eliminate the influence of random noise in the spectrum. An experiment on a public run-to-failure bearing dataset validates that the proposed method can effectively extract an incipient bearing fault characteristic frequency (FCF) from strong background noise. Furthermore, the experiment on the inter-shaft bearing of an aero-engine test platform validates the effectiveness and superiority of the proposed DIES method. The experimental results demonstrate that this proposed method can clearly extract fault-related information from dual-frequency excitation interference. Even amid strong background noise, it precisely reveals the inter-shaft bearing’s fault-related spectral components. Full article

To address the challenges posed by weak early fault signal features, strong noise interference, low diagnostic accuracy, poor reliability when using single information sources, and the limited availability of high-quality samples in practical applications for permanent magnet synchronous motor (PMSM) bearings, this paper proposes an early bearing fault diagnosis method based on Hippopotamus Optimization Variational Mode Decomposition (HO-VMD) and weighted evidence fusion of current–vibration signals. The HO algorithm is employed to optimize the parameters of VMD for adaptive modal decomposition of current and vibration signals, resulting in the generation of intrinsic mode functions (IMFs). These IMFs are then selected and reconstructed based on their kurtosis to suppress noise and harmonic interference. Subsequently, the reconstructed signals are demodulated using the Teager–Kaiser Energy Operator (TKEO), and both time-domain and energy spectrum features are extracted. The reliability of these features is utilized to adaptively weight the basic probability assignment (BPA) functions. Finally, a weighted modified Dempster–Shafer evidence theory (WMDST) is applied to fuse multi-source feature information, enabling an accurate assessment of the PMSM bearing health status. The experimental results demonstrate that the proposed method significantly enhances the signal-to-noise ratio (SNR) and enables precise diagnosis of early bearing faults even in scenarios with limited sample sizes. Full article

Interpreting diagnostic imaging and identifying clinically relevant features remain challenging tasks, particularly for novice radiologists who often lack structured guidance and expert feedback. To bridge this gap, we propose an Eye-Gaze Guided Multimodal Fusion framework that leverages expert eye-tracking data to enhance learning and decision-making in medical image interpretation. By integrating chest X-ray (CXR) images with expert fixation maps, our approach captures radiologists’ visual attention patterns and highlights regions of interest (ROIs) critical for accurate diagnosis. The fusion model utilizes a shared backbone architecture to jointly process image and gaze modalities, thereby minimizing the impact of noise in fixation data. We validate the system’s interpretability using Gradient-weighted Class Activation Mapping (Grad-CAM) and assess both classification performance and explanation alignment with expert annotations. Comprehensive evaluations, including robustness under gaze noise and expert clinical review, demonstrate the framework’s effectiveness in improving model reliability and interpretability. This work offers a promising pathway toward intelligent, human-centered AI systems that support both diagnostic accuracy and medical training. Full article

Effective fault feature extraction and classification methods serve as the foundation for achieving the efficient fault diagnosis of planetary gearboxes. Considering the vibration signals of planetary gearboxes that contain both symmetrical and asymmetrical components, this paper proposes a novel feature extraction method integrating an adaptive multi-bandpass filter (AMBPF) and refined composite multi-scale fuzzy entropy (RCMFE). And a dream optimization algorithm (DOA)–least squares support vector machine (LSSVM) is also proposed for fault classification. Firstly, the AMBPF is proposed, which can effectively and adaptively separate the meshing frequencies, harmonic frequencies, and their sideband frequency information of the planetary gearbox, and is combined with RCMFE for fault feature extraction. Secondly, the DOA is employed to optimize the parameters of the LSSVM, aiming to enhance its classification efficiency. Finally, the fault diagnosis of the planetary gearbox is achieved by the AMBPF, RCMFE, and DOA-LSSVM. The experimental results demonstrate that the proposed method achieves significantly higher diagnostic efficiency and exhibits superior noise immunity in planetary gearbox fault diagnosis. Full article

The rapid spread of COVID-19 increased the need for speedy diagnostic tools, which led scientists to conduct extensive research on deep learning (DL) applications that use chest imaging, such as chest X-ray (CXR) and computed tomography (CT). This review examines the development and performance of DL architectures, notably convolutional neural networks (CNNs) and emerging vision transformers (ViTs), in identifying COVID-19-related lung abnormalities. Individual ResNet architectures, along with CNN models, demonstrate strong diagnostic performance through the transfer protocol; however, ViTs provide better performance, with improved readability and reduced data requirements. Multimodal diagnostic systems now incorporate alternative methods, in addition to imaging, which use lung ultrasounds, clinical data, and cough sound evaluation. Information fusion techniques, which operate at the data, feature, and decision levels, enhance diagnostic performance. However, progress in COVID-19 detection is hindered by ongoing issues stemming from restricted and non-uniform datasets, as well as domain differences in image standards and complications with both diagnostic overfitting and poor generalization capabilities. Recent developments in COVID-19 diagnosis involve constructing expansive multi-noise information sets while creating clinical process-oriented AI algorithms and implementing distributed learning protocols for securing information security and system stability. While deep learning-based COVID-19 detection systems show strong potential for clinical application, broader validation, regulatory approvals, and continuous adaptation remain essential for their successful deployment and for preparing future pandemic response strategies. Full article