Search Results (4,021)

Accurately predicting how quickly people will adopt electric vehicles (EVs) is vital for planning charging stations, managing supply chains, and shaping climate policy. We present a forecasting model that uses three separate Long Short‑Term Memory (LSTM) branches—one for past EV sales, one for infrastructure and policy signals, and one for economic trends. An attention mechanism first highlights the most important weeks in each branch, then decides which branch matters most at any point in time. Trained end‑to‑end on publicly available data, the model beats traditional statistical methods and newer deep learning baselines while remaining small enough to run efficiently. An ablation study shows that every branch and both attention steps improve accuracy, and that adding policy and economic data helps more than relying on EV history alone. Because the network is modular and its attention weights are easy to interpret, it can be extended to produce confidence intervals, include physical constraints, or forecast adoption of other clean‑energy technologies. Full article

Natural fiber-based biocomposites are rapidly gaining traction in sustainable manufacturing. However, their supply chain (SC) designs at the feedstock pre-processing stage often lack robust multicriteria decision-making evaluations, which can impact downstream processes and final product quality. This case study proposes a sustainability-driven multicriteria decision-making framework for selecting pre-processing equipment configurations within a hemp-based biocomposite SC. Using a cradle-to-gate system boundary, four alternative configurations combining balers (square vs. round) and hammer mills (full-screen vs. half-screen) are evaluated. The analytical network process (ANP) model is used to evaluate alternative SC configurations while capturing the interdependencies among environmental, economic, social, and technical sustainability criteria. These criteria are further refined with the inclusion of sub-criteria, resulting in a list of 11 key performance indicators (KPIs). To evaluate ranking robustness, a non-linear programming (NLP)-based sensitivity model is developed, which minimizes the weight perturbations required to trigger rank reversals, using an IPOPT solver. The results indicated that the Half-Round setup provides the most balanced sustainability performance, while Full-Square performs best in economic and environmental terms but ranks lower socially and technically. Also, the ranking was most sensitive to the weight of the system reliability and product quality criteria, with up to a 100% shift being required to change the top choice under the ANP model, indicating strong robustness. Overall, the proposed framework enables decision-makers to incorporate uncertainty, interdependencies, and sustainability-related KPIs into the early-stage SC design of bio-based composite materials. Full article

Protein–polyelectrolyte nanostructures assembled via electrostatic interactions offer versatile applications in biomedicine, tissue engineering, and food science. However, several open questions remain regarding their intermolecular interactions and the influence of external conditions—such as temperature and pH—on their assembly, stability, and responsiveness. This study explores the formation and stability of networks between poly(acrylic acid) (PAA) and lysozyme (LYZ) at the nanoscale upon thermal treatment, using a combination of experimental and simulation measures. Experimental techniques of static and dynamic light scattering (SLS and DLS), Fourier transform infrared spectroscopy (FTIR), and circular dichroism (CD) are combined with all-atom molecular dynamics simulations. Model systems consisting of multiple PAA and LYZ molecules explore collective assembly and complexation in aqueous solution. Experimental results indicate that electrostatic complexation occurs between PAA and LYZ at pH values below LYZ’s isoelectric point. This leads to the formation of nanoparticles (NPs) with radii ranging from 100 to 200 nm, most pronounced at a PAA/LYZ mass ratio of 0.1. These complexes disassemble at pH 12, where both LYZ and PAA are negatively charged. However, when complexes are thermally treated (TT), they remain stable, which is consistent with earlier findings. Atomistic simulations demonstrate that thermal treatment induces partially reversible structural changes, revealing key microscopic features involved in the stabilization of the formed network. Although electrostatic interactions dominate under all pH and temperature conditions, thermally induced conformational changes reorganize the binding pattern, resulting in an increased number of contacts between LYZ and PAA upon thermal treatment. The altered hydration associated with conformational rearrangements emerges as a key contributor to the stability of the thermally treated complexes, particularly under conditions of strong electrostatic repulsion at pH 12. Moreover, enhanced polymer chain associations within the network are observed, which play a crucial role in complex stabilization. These insights contribute to the rational design of protein–polyelectrolyte materials, revealing the origins of association under thermally induced structural rearrangements. Full article

To evaluate the efficiency of innovation development in China’s high-tech manufacturing industry, this paper constructs a two-stage dynamic network cross-efficiency model. This model divides innovation activities into two stages: technology research and development and achievement transformation and introduces a 2-year lag period in the technology research and development stage and a 1-year lag period in the achievement transformation stage. It proposes the overall efficiency and efficiency models for each stage. The model was applied to 30 provinces in China, and the results showed that most provinces have achieved relatively ideal results in the overall efficiency and achievement transformation stage of high-tech manufacturing, while the efficiency in the technology research and development stage is generally lower than that in the achievement transformation stage. It is recommended that enterprises increase their R&D investments, break through technological barriers, and optimize the innovation chain. Full article

Global supply chains often face uncertainties in production lead times, fluctuating exchange rates, and varying tariff regulations, all of which can significantly impact total profit. To address these challenges, this study formulates a multi-country supply chain problem as a Semi-Markov Decision Process (SMDP), integrating both currency variability and tariff levels. Using a Q-learning-based method (SMART), we explore three scenarios: (1) wide currency gaps under a uniform tariff, (2) narrowed currency gaps encouraging more local sourcing, and (3) distinct tariff structures that highlight how varying duties can reshape global fulfillment decisions. Beyond these baselines we analyze uncertainty-extended variants and targeted sensitivities (quantity discounts, tariff escalation, and the joint influence of inventory holding costs and tariff costs). Simulation results, accompanied by policy heatmaps and performance metrics, illustrate how small or large shifts in exchange rates and tariffs can alter sourcing strategies, transportation modes, and inventory management. A Deep Q-Network (DQN) is also applied to validate the Q-learning policy, demonstrating alignment with a more advanced neural model for moderate-scale problems. These findings underscore the adaptability of reinforcement learning in guiding practitioners and policymakers, especially under rapidly changing trade environments where exchange rate volatility and incremental tariff changes demand robust, data-driven decision-making. Full article

Promoting the sustainable development of virtual water trade is of great significance to safeguarding China’s water resource security and balanced regional economic growth. This study analyzes the virtual water trade network among 31 Chinese provinces based on multi-regional input–output tables from 2012, 2015, and 2017, using total trade decomposition, social network analysis, and exponential random graph models. The key findings are as follows: (1) The total virtual water trade volume remains stable, with Xinjiang, Jiangsu, and Guangdong as the core regions, while remote areas such as Shaanxi and Gansu have lower trade volumes. The primary industry dominates, and it is driven by simple value chains. (2) Provinces such as Xinjiang, Heilongjiang, and Jiangsu form the network’s core. Network density and symmetry increased from 2012 to 2015 but declined slightly in 2017, with efficiency peaking and then dropping, and the clustering coefficient decreased annually. Four economic sectors exhibit distinct interactions: frequent two-way flows in Sector 1, significant inflows in Sector 2, prominent net spillovers in Sector 3, and key brokers in Sector 4. (3) The network evolved from a core-periphery structure with weak ties to a stable, heterogeneous, and resilient system. (4) Influencing factors, such asper capita water resources, economic development, and population, significantly impact trade. Similarities in economic levels, population, and water endowments promote trade, while spatial distance has a limited effect, with geographic proximity showing a significant negative impact on long-distance trade. Full article

Quantum secret sharing (QSS) faces inherent limitations in scaling to multi-user networks due to excess noise introduced by highly asymmetric beam splitters (HABSs) in chain-structured topologies. To overcome this challenge, we propose an optical frequency comb-based continuous-variable QSS (OFC CV-QSS) scheme that establishes parallel frequency channels between users and the dealer via OFC-generated multi-wavelength carriers. By replacing the chain-structured links with dedicated frequency channels and integrating the Chinese remainder theorem (CRT) with a decentralized architecture, our design eliminates excess noise from all users using HABS while providing mathematical- and physical-layer security. Simulation results demonstrate that the scheme achieves a more than 50% improvement in maximum transmission distance compared to chain-based QSS, with significantly slower performance degradation as users scale to 20. Numerical simulations confirm the feasibility of this theoretical framework for multi-user quantum networks, offering dual-layer confidentiality without compromising key rates. Full article

Entropy is a foundational concept across scientific domains, playing a role in understanding disorder, randomness, and uncertainty within systems. This study applies Shannon’s entropy in information theory to evaluate and manage complexity in industrial supply chain management. The purpose of the study is to propose a quantitative modeling method, employing Shannon’s entropy model as a proxy to assess the complexity in SCs. The underlying assumption is that information entropy serves as a proxy for the complexity of the SC. The research method is quantitative modeling, which is applied to four focal companies from the agrifood and metalworking industries in Southern Brazil. The results showed that companies prioritizing cost and quality exhibit lower complexity compared to those emphasizing flexibility and dependability. Additionally, information flows related to specially engineered products and deliveries show significant differences in average entropies, indicating that organizational complexities vary according to competitive priorities. The implications of this suggest that a focus on cost and quality in SCM may lead to lower complexity, in opposition to a focus on flexibility and dependability, influencing strategic decision making in industrial contexts. This research introduces the novel application of information entropy to assess and control complexity within industrial SCs. Future studies can explore and validate these insights, contributing to the evolving field of supply chain management. Full article

In recent years, the concept of the myofascial network has transformed biomechanical understanding by emphasizing the body as an integrated, multidirectional system. This study advances that paradigm by applying graph theory to model the osteo-myofascial system as an anatomical network, enabling the identification of topologically central nodes involved in force transmission, stability, and coordination. Using the aNETomy model and the BIOMECH 3.4 database, we constructed an undirected network of 2208 anatomical nodes and 7377 biomechanical relationships. Centrality analysis (degree, betweenness, and closeness) revealed that structures such as the sacrum and thoracolumbar fascia exhibit high connectivity and strategic importance within the network. These findings, while derived from a theoretical modeling approach, suggest that such key nodes may inform targeted treatment strategies, particularly in complex or compensatory musculoskeletal conditions. The proposed concept of a polyconnective skeleton (PCS) synthesizes the most influential anatomical hubs into a functional core of the system. This framework may support future clinical and technological applications, including integration with imaging modalities, real-time monitoring, and predictive modeling for personalized and preventive medicine. Full article

With the increasing scale of industrial devices and the growing complexity of multi-source heterogeneous sensor data, traditional methods struggle to address challenges in fault detection, data security, and trustworthiness. Ensuring tamper-proof data storage and improving prediction accuracy for imbalanced anomaly detection for potential deployment in the Industrial Internet of Things (IIoT) remain critical issues. This study proposes a blockchain-powered Long Short-Term Memory Network (LSTM)–Attention hybrid model: an LSTM-based Encoder–Attention–Decoder (LEAD) for industrial device anomaly detection. The model utilizes an encoder–attention–decoder architecture for processing multivariate time series data generated by industrial sensors and smart contracts for automated on-chain data verification and tampering alerts. Experiments on real-world datasets demonstrate that the LEAD achieves an $F_{0.1}$ score of 0.96, outperforming baseline models (Recurrent Neural Network (RNN): 0.90; LSTM: 0.94; and Bi-directional LSTM (Bi-LSTM, 0.94)). We simulate the system using a private FISCO-BCOS network with a multi-node setup to demonstrate contract execution, anomaly data upload, and tamper alert triggering. The blockchain system successfully detects unauthorized access and data tampering, offering a scalable solution for device monitoring. Full article

Background: Short-chain fatty acids (SCFAs), microbial metabolites also known as postbiotics, are essential for maintaining gut health. However, their antiproliferative effects on gastric cancer cells and potential interactions with conventional therapies remain underexplored. This study aimed to investigate the effects of three SCFA salts—magnesium acetate (A), sodium propionate (P), and sodium butyrate (B)—individually and in combination (APB), as well as in combination with dexamethasone (Dex), on AGS gastric adenocarcinoma cells. Methods: AGS cells were treated with PB, AP, AB, APB, Dex, and APB+Dex. Cell viability was assessed to determine antiproliferative effects, and the IC₅₀ of APB was calculated. Flow cytometry was used to evaluate apoptosis and necrosis. Reactive oxygen species (ROS) levels were measured to assess oxidative stress. Proteomic analysis via LC-MS was performed to identify differential protein expression and related pathways impacted by the treatments. Results: SCFA salts showed significant antiproliferative effects on AGS cells, with APB exhibiting a combined IC₅₀ of 568.33 μg/mL. The APB+Dex combination demonstrated strong synergy (combination index = 0.76) and significantly enhanced growth inhibition. Both APB and APB+Dex induced substantial apoptosis (p < 0.0001) with minimal necrosis. APB alone significantly increased ROS levels (p < 0.0001), while Dex moderated this effect in the combination group APB+Dex (p < 0.0001). Notably, the APB+Dex treatment synergistically targeted multiple tumour-promoting mechanisms, including the impairment of redox homeostasis through SLC7A11 suppression, and inhibition of the haemostasis, platelet activation network and NF-κB signalling pathway via downregulation of NFKB1 (−1.34), exemplified by increased expression of SERPINE1 (1.99) within the “Response to elevated platelet cytosolic Ca²⁺” pathway. Conclusions: These findings showed a multifaceted anticancer mechanism by APB+Dex that may collectively impair cell proliferation, survival signalling, immune modulation, and tumour microenvironment support in gastric cancer. Full article

Using common corn stalks as raw materials, a functional dense-structured carbon microsphere with good elastic deformation and certain rigid support was modified from biomass through a step-by-step hydrothermal method. The composition, thermal stability, fluid-loss reduction performance, and reservoir protection performance of the modified carbon microspheres were studied. Research indicates that after hydrothermal treatment, under the multi-level structural action of a small amount of proteins in corn stalks, the naturally occurring cellulose, polysaccharide organic compounds, and part of the ash in the stalks are adsorbed and encapsulated within the long-chain network structure formed by proteins and cellulose. By attaching silicate nanoparticles with certain rigidity from the ash to the relatively stable chair-type structure in cellulose, functional dense-structured carbon microspheres were ultimately prepared. These carbon microspheres could still effectively reduce fluid loss at 200 °C. The permeability recovery value of the cores treated with modified biomass carbon microspheres during flowback reached as high as 88%, which was much higher than that of the biomass itself. With the dense network-like chain structure supplemented by small-molecule aldehydes and silicate ash, the subsequent invasion of drilling fluid was successfully prevented, and a good sealing effect was maintained even under high-temperature and high-pressure conditions. Moreover, since this functional dense-structured carbon microsphere achieved sealing through a physical mechanism, it did not cause damage to the formation, showing a promising application prospect. Full article

Collaborative business ecosystems (CBEs) are increasingly exposed to disruptive events (e.g., pandemics, supply chain breakdowns, cyberattacks) that challenge organizational adaptability and value creation. Traditional approaches to resilience and robustness often fail to capture the full range of systemic responses. This study introduces a unified mathematical framework to evaluate four crisis response modes—plasticity, resilience, transformative resilience, and antifragility—within complex adaptive networks. Grounded in complex systems and collaborative network theory, our model formalizes both internal organizational capabilities (e.g., adaptability, learning, innovation, structural flexibility) and strategic interventions (e.g., optionality, buffering, information sharing, fault-injection protocols), linking them to pre- and post-crisis performance via dynamic adjustment functions. A composite performance score is defined across four dimensions (Innovation, Contribution, Prestige, and Responsiveness to Business Opportunities), using capability–strategy interaction matrices, weighted performance change functions, and structural transformation modifiers. The sensitivity analysis and scenario simulations enable a comparative evaluation of organizational configurations, strategy impacts, and phase-transition thresholds under crisis. This indicator-based formulation provides a quantitative bridge between resilience theory and practice, facilitating evidence-based crisis management in networked business environments. Full article

Blockchain provides the opportunity for organizations to execute trustable collaborations through smart contract automations. However, linkability problems exist in blockchain-based collaboration platforms due to privacy leakages, which, when exploited, will result in tracing transaction patterns to users and exposing collaborating organizations and parties. Some privacy-preserving mechanisms have been adopted to reduce linkability problems through the integration of access control systems to smart contracts, off-chain data storage, usage of permissioned blockchain, etc. Still, linkability problems persist in applications deployed in both private and public blockchain networks. Zero-knowledge proof (ZKP) systems provide mechanisms for verifying the correctness of transactions and actions executed on the blockchain without revealing complete information about the transaction. Hence, ZKP systems provide a potential solution to eliminating linkability problems in blockchain-based collaboration systems. The objective of this paper is to identify various linkability problems that exist in blockchain-enabled collaboration systems and understand how ZKP algorithms and smart contract frameworks can be used in addressing the linkability problems. Furthermore, a proof of concept (PoC) is implemented and simulated to demonstrate a ZKP system for a privacy-preserving feedback mechanism that mitigates linkability problems in collaboration systems. The scenario-based results from the PoC evaluation show that a feedback system that includes project participants’ verification through membership proofs, verification of on-time submission of feedback through range proofs, and encrypted calculation of feedback scores through homomorphic arithmetic provides a privacy-aware system for executing collaborations on the blockchain without linking project participants. Full article

This paper investigates the interplay between rubber network damage, carbon black (CB) network damage, heat exchange, and voiding mechanisms in filled Styrene-butadiene rubber (SBR) under cyclic loading. To do so, three carbon black filled SBR composites, SBR5, SBR30 and SBR60 are studied. The study aims to quantify molecular damage and its role in inducing reversible or irreversible heat flow and voiding behavior to inform the design of more resilient rubber composites with improved fatigue life and thermal management capabilities. The study effectively demonstrated how increasing carbon black content, particularly in SBR60, leads to a shift from mostly reversible to irreversible and cumulative damage mechanisms during cyclic loading, as evidenced by thermal, volumetric, and electrical resistivity changes. In particular, we identify a critical mechanical energy of 7 MJ.m⁻³ associated with such transition. These irreversible changes are strongly linked to the damage and re-arrangement of the carbon black filler network, as well as the rubber chains network and the formation/growth of voids, while reversible mechanisms are likely related to rubber chains alignment associated with entropic elasticity. Full article