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420 Results Found

  • Article
  • Open Access
1 Citations
2,798 Views
13 Pages

14 October 2024

Existing studies have demonstrated significant sex differences in the neural mechanisms of daily life and neuropsychiatric disorders. The hierarchical organization of the functional brain network is a critical feature for assessing these neural mecha...

  • Article
  • Open Access
10 Citations
5,113 Views
19 Pages

MoCLORA—An Architecture for Legged-and-Climbing Modular Bio-Inspired Robotic Organism

  • Carlos Prados,
  • Miguel Hernando,
  • Ernesto Gambao and
  • Alberto Brunete

MoCLORA (Modular Climbing-and-Legged Robotic Organism Architecture) is a software framework for climbing bio-inspired robotic organisms composed of modular robots (legs). It is presented as a modular low-level architecture that coordinates the module...

  • Article
  • Open Access
2,179 Views
10 Pages

Basicranial Modular Organization. A Study in the Araucanian Horse of Colombia

  • Arcesio Salamanca-Carreño,
  • Pere M. Parés-Casanova,
  • René Alejandro Crosby-Granados,
  • Mauricio Vélez-Terranova and
  • Jannet Bentez-Molano

28 March 2023

The skull is divided into neurocranium and splanchnocranium, and its variation allows ecomorphological studies to learn about possible evolutionary and adaptive characteristics. The basicranial organization of the neurocranium and splanchnocranium mo...

  • Article
  • Open Access
28 Citations
12,349 Views
20 Pages

2 July 2014

The costs of the surface infrastructure in mid-enthalpy geothermal power systems, especially in remote areas, could be reduced by using small, modular Organic Rankine Cycle (ORC) power plants. Thermal-economic criteria have been devised to standardiz...

  • Article
  • Open Access
28 Citations
8,296 Views
23 Pages

24 February 2017

Industrial waste heat recovery by means of an Organic Rankine Cycle (ORC) can contribute to the reduction of CO2 emissions from industries. Before market penetration, high efficiency modular concepts have to be developed to achieve appropriate econom...

  • Article
  • Open Access
61 Citations
8,600 Views
16 Pages

A Comparative Exergoeconomic Analysis of Waste Heat Recovery from a Gas Turbine-Modular Helium Reactor via Organic Rankine Cycles

  • Naser Shokati,
  • Farzad Mohammadkhani,
  • Mortaza Yari,
  • Seyed M. S. Mahmoudi and
  • Marc A. Rosen

30 April 2014

A comparative exergoeconomic analysis is reported for waste heat recovery from a gas turbine-modular helium reactor (GT-MHR) using various configurations of organic Rankine cycles (ORCs) for generating electricity. The ORC configurations studied are:...

  • Article
  • Open Access
1 Citations
2,248 Views
19 Pages

2 September 2024

Under the background of “dual carbon” development goals, the rapid expansion of internet data centers driven by advancements in 5G technology has led to increased energy consumption and elevated heat densities within the server rooms in t...

  • Article
  • Open Access
4 Citations
1,502 Views
23 Pages

European Green Deal: Substantiation of the Rational Configuration of the Bioenergy Production System from Organic Waste

  • Inna Tryhuba,
  • Anatoliy Tryhuba,
  • Taras Hutsol,
  • Szymon Szufa,
  • Szymon Glowacki,
  • Oleh Andrushkiv,
  • Roman Padyuka,
  • Oleksandr Faichuk and
  • Nataliia Slavina

9 September 2024

A review of the current state of the theory and practice of bioenergy production from waste allowed us to identify the scientific and applied problem of substantiating the rational configuration of a modular anaerobic bioenergy system, taking into ac...

  • Article
  • Open Access
2 Citations
1,459 Views
24 Pages

24 September 2024

Dalian Island, located in the northwest of Pingtan County, Fujian Province, China, has been an important junction on the Maritime Silk Road since the Tang dynasty. This study focuses on sauce-glazed ceramic ware from the Song dynasty salvaged from th...

  • Article
  • Open Access
1,519 Views
16 Pages

31 October 2025

Multi-organ-chip (MOC) models provide a plethora of auspicious opportunities to replace current in vitro and in vivo models for a more systemic investigation of human (patho-)physiology for drug development and personalized medicine. Integration of i...

  • Article
  • Open Access
44 Citations
9,353 Views
14 Pages

Cytostretch, an Organ-on-Chip Platform

  • Nikolas Gaio,
  • Berend Van Meer,
  • William Quirós Solano,
  • Lambert Bergers,
  • Anja Van de Stolpe,
  • Christine Mummery,
  • Pasqualina M. Sarro and
  • Ronald Dekker

14 July 2016

Organ-on-Chips (OOCs) are micro-fabricated devices which are used to culture cells in order to mimic functional units of human organs. The devices are designed to simulate the physiological environment of tissues in vivo. Cells in some types of OOCs...

  • Article
  • Open Access
18 Citations
5,660 Views
43 Pages

Multipotent Systems: Combining Planning, Self-Organization, and Reconfiguration in Modular Robot Ensembles

  • Oliver Kosak,
  • Constantin Wanninger,
  • Alwin Hoffmann,
  • Hella Ponsar and
  • Wolfgang Reif

20 December 2018

Mobile multirobot systems play an increasing role in many disciplines. Their capabilities can be used, e.g., to transport workpieces in industrial applications or to support operational forces in search and rescue scenarios, among many others. Depend...

  • Article
  • Open Access
2 Citations
1,690 Views
16 Pages

The Profile of Network Spontaneous Activity and Functional Organization Interplay in Hierarchically Connected Modular Neural Networks In Vitro

  • Yana Pigareva,
  • Arseniy Gladkov,
  • Vladimir Kolpakov,
  • Victor B. Kazantsev,
  • Irina Mukhina and
  • Alexey Pimashkin

Modern microtechnology methods are widely used to create neural networks on a chip with a connection architecture demonstrating properties of modularity and hierarchy similar to brain networks. Such in vitro networks serve as a valuable model for stu...

  • Article
  • Open Access
225 Views
20 Pages

Analysis of Organic Growth Rules: Variability and Flexibility in Industrialised Three-Dimensional Modular Aggregation Systems

  • César Daniel Sirvent-Pérez,
  • Maria Isabel Pérez-Millán,
  • Carlos Pérez-Carramiñana and
  • Andrea Marie Chávez-Bonneau

Over the past decade, the convergence between industrialised construction and computational design has opened up new possibilities for industrialised modular housing. This research focuses on the ability to generate variable and flexible housing conf...

  • Feature Paper
  • Article
  • Open Access
3 Citations
2,978 Views
14 Pages

An Organ-on-a-Chip Modular Platform with Integrated Immunobiosensors for Monitoring the Extracellular Environment

  • Anastasia Kanioura,
  • Myrto Kyriaki Filippidou,
  • Dimitra Tsounidi,
  • Panagiota S. Petrou,
  • Stavros Chatzandroulis and
  • Angeliki Tserepi

25 June 2025

OoC systems employing human cells mirror the functionality of human organs and faithfully simulate their physiological microfluidic environment. Despite the potential of OoC technology in emulating tissue complexity, a significant gap persists in the...

  • Article
  • Open Access
6 Citations
3,311 Views
12 Pages

25 July 2020

A new organically templated uranyl molybdate [C3H9NH+]4[(UO2)3(MoO4)5] was prepared by a hydrothermal method at 220 °C. The compound is monoclinic, Сс, a = 16.768(6), b = 20.553(8), c = 11.897(4) Å, β = 108.195(7), V = 3895(2) Å3...

  • Review
  • Open Access
32 Citations
5,789 Views
25 Pages

Modular Strategies to Build Cell-Free and Cell-Laden Scaffolds towards Bioengineered Tissues and Organs

  • Aurelio Salerno,
  • Giuseppe Cesarelli,
  • Parisa Pedram and
  • Paolo Antonio Netti

1 November 2019

Engineering three-dimensional (3D) scaffolds for functional tissue and organ regeneration is a major challenge of the tissue engineering (TE) community. Great progress has been made in developing scaffolds to support cells in 3D, and to date, several...

  • Article
  • Open Access
2,271 Views
14 Pages

Development of a Modular miRNA-Responsive Biosensor for Organ-Specific Evaluation of Liver Injury

  • Xinxin Zhang,
  • Tingting Wang,
  • Xiangqing Fan,
  • Meixia Wang,
  • Zhixi Duan,
  • Fang He,
  • Hong-Hui Wang and
  • Zhihong Li

20 September 2024

MicroRNAs (miRNAs) are increasingly being considered essential diagnostic biomarkers and therapeutic targets for multiple diseases. In recent years, researchers have emphasized the need to develop probes that can harness extracellular miRNAs as input...

  • Article
  • Open Access
4 Citations
2,330 Views
18 Pages

Thermodynamic Analysis and Optimization of Binary CO2-Organic Rankine Power Cycles for Small Modular Reactors

  • Vladimir Kindra,
  • Igor Maksimov,
  • Daniil Patorkin,
  • Andrey Rogalev and
  • Nikolay Rogalev

15 May 2024

Small nuclear power plants are a promising direction of research for the development of carbon-free energy in isolated power systems and in remote regions with undeveloped infrastructure. Improving the efficiency of power units integrated with small...

  • Review
  • Open Access
8 Citations
9,505 Views
23 Pages

Modular Self-Configurable Robots—The State of the Art

  • Lu Anh Tu Vu,
  • Zhuming Bi,
  • Donald Mueller and
  • Nashwan Younis

14 September 2023

Modular self-configurable robot (MSR) systems have been investigated for decades, and their applications have been widely explored to meet emerging automation needs in various applications, such as space exploration, manufacturing, defense, medical i...

  • Article
  • Open Access
5 Citations
4,088 Views
21 Pages

Torque-Based Control of a Bio-Inspired Modular Climbing Robot

  • Carlos Prados,
  • Miguel Hernando,
  • Ernesto Gambao and
  • Alberto Brunete

19 July 2023

This article presents a generalizable, low computational cost, simple, and fast gravity compensation method for legged robots with a variable number of legs. It is based on the static problem, which is a reduction in the dynamic model of the robot th...

  • Review
  • Open Access
47 Citations
7,924 Views
22 Pages

Modular Microfluidics: Current Status and Future Prospects

  • Xiaochen Lai,
  • Mingpeng Yang,
  • Hao Wu and
  • Dachao Li

22 August 2022

This review mainly studies the development status, limitations, and future directions of modular microfluidic systems. Microfluidic technology is an important tool platform for scientific research and plays an important role in various fields. With t...

  • Review
  • Open Access
4 Citations
2,646 Views
17 Pages

Indoor Volatile Organic Compounds in Prefabricated Timber Buildings—Challenges and Opportunities for Sustainability

  • Nigel Goodman,
  • Priyadarsini Rajagopalan,
  • Matthew Francis,
  • Neda Nematollahi,
  • Sotiris Vardoulakis and
  • Anne Steinemann

30 November 2024

Prefabricated timber buildings offer a low-carbon approach that can help reduce the environmental impact of the building and construction sectors. However, construction materials such as manufactured timber products can emit a range volatile organic...

  • Article
  • Open Access
2 Citations
1,440 Views
30 Pages

28 April 2025

There are a large number of atypical traditional villages in Huizhou, China. These villages are facing a huge increase in spatial renewal and construction due to the problems of fragmented historical space and unbalanced spatial structure. Therefore,...

  • Entry
  • Open Access
12 Citations
9,918 Views
14 Pages

Challenges for Nanotechnology

  • Johann Michael Köhler

The term “Nanotechnology” describes a large field of scientific and technical activities dealing with objects and technical components with small dimensions. Typically, bodies that are in–at least–two dimensions smaller than 0.1 µm are regarded as “n...

  • Review
  • Open Access
4 Citations
3,033 Views
16 Pages

16 October 2021

The control of gene expression at a transcriptional level requires a widespread landscape of regulatory elements. Central to these regulatory circuits are enhancers (ENHs), which are defined as cis-acting DNA elements able to increase the transcripti...

  • Article
  • Open Access
10 Citations
4,796 Views
12 Pages

5 December 2019

The modular-based multi-organ-on-a-chip enables more stable and flexible configuration to better mimic the complex biological phenomena for versatile biomedical applications. However, the existing magnetic-based interconnection modes are mainly reali...

  • Article
  • Open Access
6 Citations
5,709 Views
22 Pages

In this paper, we propose a set of rules for developing modular architectures. We first consider the well-known concept of “Design Rules” advanced by Baldwin and Clark. We then propose a broader conceptualization called “Modularity...

  • Article
  • Open Access
1,471 Views
12 Pages

Fault-Tolerant Phototaxis of a Modular System Inspired by Gonium pectorale Using Phase-Based Control

  • Kohei Nishikawa,
  • Yuki Origane,
  • Hiroki Etchu and
  • Daisuke Kurabayashi

19 May 2024

In this study, we proposed a model for modular robots in which autonomous decentralized modules adaptively organize their behavior. The phototaxis of Gonium pectorale, a species of volvocine algae, was modeled as a modular system, and a fault-toleran...

  • Article
  • Open Access
9 Citations
8,750 Views
18 Pages

HexaMob—A Hybrid Modular Robotic Design for Implementing Biomimetic Structures

  • Sasanka Sankhar Reddy CH.,
  • Sharath Patlolla,
  • Anita Agrawal and
  • Anupama K. R.

16 October 2017

Modular robots are capable of forming primitive shapes such as lattice and chain structures with the additional flexibility of distributed sensing. The biomimetic structures developed using such modular units provides ease of replacement and reconfig...

  • Review
  • Open Access
10 Citations
4,124 Views
23 Pages

Thermo-Environmental Performance of Modular Building Envelope Panel Technologies: A Focused Review

  • Mohammed Alhaji Mohammed,
  • Ismail M. Budaiwi,
  • Mohammed A. Al-Osta and
  • Adel A. Abdou

Modular construction is becoming famous for buildings because it allows a high degree of prefabrication, with individual modules easily transported and installed. Building envelope optimization is vital as it protects buildings from undesirable exter...

  • Feature Paper
  • Article
  • Open Access
8 Citations
5,188 Views
33 Pages

Self-Assembly and Self-Repair during Motion with Modular Robots

  • Robert H. Peck,
  • Jon Timmis and
  • Andy M. Tyrrell

Self-reconfigurable modular robots consist of multiple modular elements and have the potential to enable future autonomous systems to adapt themselves to handle unstructured environments, novel tasks, or damage to their constituent elements. This pap...

  • Review
  • Open Access
16 Citations
4,049 Views
19 Pages

17 August 2023

Biological modularity refers to the organization of living systems into separate functional units that interact in different combinations to promote individual well-being and species survival. Modularity provides a framework for generating and select...

  • Article
  • Open Access
1 Citations
1,153 Views
26 Pages

13 July 2024

Source code complexity of legacy object-oriented (OO) software has a trickle-down effect over the key activities of software development and maintenance. Package-based OO design is widely believed to be an effective modularization. Recently, theories...

  • Concept Paper
  • Open Access
31 Citations
13,502 Views
17 Pages

The principle of self-organization has acquired a fundamental significance in the newly emerging field of computational philosophy. Self-organizing systems have been described in various domains in science and philosophy including physics, neuroscien...

  • Article
  • Open Access
859 Views
19 Pages

8 November 2025

The mandible of domestic dogs represents a key structure in veterinary anatomy. This study tested the hypothesis that mandibular shape variation in adult mesocephalic dogs follows a non-random modular pattern with limited allometric influence. A tota...

  • Feature Paper
  • Article
  • Open Access
2 Citations
3,690 Views
16 Pages

Individual Topological Analysis of Synchronization-Based Brain Connectivity

  • Angela Lombardi,
  • Nicola Amoroso,
  • Domenico Diacono,
  • Alfonso Monaco,
  • Sabina Tangaro and
  • Roberto Bellotti

8 May 2020

Functional connectivity analysis aims at assessing the strength of functional coupling between the signal responses in distinct brain areas. Usually, functional magnetic resonance imaging (fMRI) time series connections are estimated through zero-lag...

  • Article
  • Open Access
11 Citations
4,511 Views
12 Pages

Intra- and Inter-Modular Connectivity Alterations in the Brain Structural Network of Spinocerebellar Ataxia Type 3

  • Chi-Wen Jao,
  • Bing-Wen Soong,
  • Tzu-Yun Wang,
  • Hsiu-Mei Wu,
  • Chia-Feng Lu,
  • Po-Shan Wang and
  • Yu-Te Wu

23 March 2019

In addition to cerebellar degeneration symptoms, patients with spinocerebellar ataxia type 3 (SCA3) exhibit extensive involvements with damage in the prefrontal cortex. A network model has been proposed for investigating the structural organization a...

  • Article
  • Open Access
1 Citations
898 Views
15 Pages

17 September 2025

The growing demand for child-friendly, growth-adaptive furniture necessitates the establishment of an evaluation framework that integrates user perception and modular design. This study has proposed a model framework that encompasses eight dimensions...

  • Article
  • Open Access
1 Citations
1,215 Views
26 Pages

19 February 2025

This study introduces an automated method for constructing residential functional modules from the perspective of user behavior. By integrating the design structure matrix (DSM) and Fuzzy C-Means Clustering Algorithm (FCM), this approach systematical...

  • Article
  • Open Access
7 Citations
3,263 Views
17 Pages

19 April 2024

Construction professionals work in silos and use traditional design and construction methods. The growing demand for rapidly built and high-quality construction is making off-site manufacturing mainstream. Studies have shown that collaboration among...

  • Article
  • Open Access
10 Citations
6,215 Views
25 Pages

Multi-Level Formation of Complex Software Systems

  • Hui Li,
  • Li-Ying Hao and
  • Rong Chen

12 May 2016

We present a multi-level formation model for complex software systems. The previous works extract the software systems to software networks for further studies, but usually investigate the software networks at the class level. In contrast to these wo...

  • Article
  • Open Access
472 Views
18 Pages

Spatial Modularity of Innate Immune Networks Across Bactrian Camel Tissues

  • Lili Guo,
  • Bin Liu,
  • Chencheng Chang,
  • Fengying Ma,
  • Le Zhou and
  • Wenguang Zhang

31 October 2025

The Bactrian camel exemplifies mammalian adaptation to deserts, but the spatial organization of its innate immune system remains uncharacterized. This study integrated transcriptomes from 110 samples across 11 major tissues and organs to resolve tiss...

  • Article
  • Open Access
3 Citations
2,303 Views
9 Pages

25 March 2023

Morphological integration and modularity refer to the degree of covariation between the different components of an anatomical structure. Modularity refers to structures that have components which covary strongly, but at the same time are relatively i...

  • Article
  • Open Access
10 Citations
8,420 Views
28 Pages

12 August 2013

Functional modules of metabolic networks are essential for understanding the metabolism of an organism as a whole. With the vast amount of experimental data and the construction of complex and large-scale, often genome-wide, models, the computer-aide...

  • Article
  • Open Access
40 Citations
9,779 Views
20 Pages

An Intelligent Modular Water Monitoring IoT System for Real-Time Quantitative and Qualitative Measurements

  • Evangelos Syrmos,
  • Vasileios Sidiropoulos,
  • Dimitrios Bechtsis,
  • Fotis Stergiopoulos,
  • Eirini Aivazidou,
  • Dimitris Vrakas,
  • Prodromos Vezinias and
  • Ioannis Vlahavas

23 January 2023

This study proposes a modular water monitoring IoT system that enables quantitative and qualitative measuring of water in terms of an upgraded version of the water infrastructure to sustain operational reliability. The proposed method could be used i...

  • Systematic Review
  • Open Access
6 Citations
9,171 Views
44 Pages

Autonomous driving technology is advancing rapidly, driven by integrating advanced intelligent systems. Autonomous vehicles typically follow a modular structure, organized into perception, planning, and control components. Unlike previous surveys, wh...

  • Article
  • Open Access
2 Citations
3,196 Views
19 Pages

The Self-Organization of Marine Microbial Networks under Evolutionary and Ecological Processes: Observations and Modeling

  • Zhenghua Liu,
  • Jianjun Wang,
  • Delong Meng,
  • Liangzhi Li,
  • Xueduan Liu,
  • Yabing Gu,
  • Qingyun Yan,
  • Chengying Jiang and
  • Huaqun Yin

13 April 2022

Evolutionary and ecological processes are primary drivers of ecological network constrictions. However, the ways that these processes underpin self-organization and modularity in networks are poorly understood. Here, we performed network analyses to...

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