Search Results (189)

Integrating neural and muscular signals into wearable robotics enables adaptive assistance during real-world tasks. This study proposes a multimodal neural interface for passive exoskeletons that combines electroencephalography (EEG) and electromyography (EMG) signals to classify motor gestures and estimate real-time cognitive and muscular effort, supported by finite-element-based biomechanical modeling. The system was implemented on the Ottobock Shoulder X passive exoskeleton© and validated using synchronous EEG–EMG acquisition via the LiveAmp platform©, a commercially available platform that was not developed specifically for this study. A hybrid CNN–LSTM architecture with deep fusion was employed to enhance robustness and responsiveness under realistic operating conditions. This study proposes a multimodal neural interface for the software-level adaptive assistance of passive upper-limb exoskeletons. While the physical device maintains a static mechanical profile, the proposed digital framework achieves adaptation by interpreting the user’s physiological and motor states. Ten healthy participants performed three functional tasks (screwing, moving the box, and lifting the box) under five assistive conditions. Finite element modeling (FEM) was used to characterize the torque–angle relationship of the passive exoskeleton and to support the interpretation of experimentally observed assistive torque profiles. The FEM model, used as an offline biomechanical analysis tool to aid in the interpretation of experimental results, has not been integrated into the real-time control loop. Results showed an average classification accuracy of 90%, an F1-score of 0.85, and inference latency below 180 ms, confirming real-time applicability. Cognitive indices such as the Cognitive Load Index (CLI) and Frontal Asymmetry Index (FAI) enabled adaptive modulation of assistance strategies without requiring active actuation, thereby preserving the device’s intrinsic passive nature. Comparative torque analysis highlighted the ergonomic benefits of passive systems in mid-range postures, while Finite Element Method (FEM) supported analysis clarified their limitations under highly dynamic loads compared to active solutions. These findings advance multimodal brain–machine interfaces for wearable robotics by integrating physiological sensing, deep learning, and biomechanical modeling, offering a safe, energy-efficient, and adaptive approach with potential rehabilitation, occupational ergonomics, and human–robot applications. Full article

The proposed methodology combines analytical control laws with adaptive mechanisms and machine-learning-assisted modules based on regression trees, random forests, and extreme gradient boosting (XGBoost). Machine learning models are employed to approximate unknown nonlinear dynamics, compensate disturbances, and adjust controller parameters, while the overall control structure is constrained by Lyapunov stability conditions. This ensures that the inclusion of data-driven components does not violate the fundamental requirement of system stability. The effectiveness of the proposed approach is evaluated through simulation experiments across three operating modes with varying degrees of nonlinearity and dynamic complexity. The results show that hybrid models incorporating ensemble machine learning methods improved performance compared with the analytical and adaptive baselines examined. XGBoost-based control achieves the lowest error values and the highest level of Lyapunov stability compliance (up to 99.3%). The main contribution of this study lies in the development of a unified synthesis framework in which machine learning is not used as a standalone control strategy but as a machine-learning-assisted support mechanism integrated into a theoretically grounded control architecture. The proposed approach provides a balance between adaptability, accuracy, and rigorous stability guarantees, suggesting potential applicability to simulation-based and offline-assisted control design tasks, while real-time embedded implementation requires additional computational optimization and validation. Full article

Antimicrobial resistance and biofilm-associated contamination continue to pose critical challenges in food safety and biomedical applications, necessitating the development of advanced antimicrobial materials with enhanced efficacy, safety, and functional adaptability. Antimicrobial nanomaterials offer versatile solutions due to their tunable physicochemical properties, surface engineering capabilities, and controlled release behaviors, enabling improved antimicrobial and antibiofilm performance across diverse systems. This review highlights the main advancements in AI-assisted design of antimicrobial nanomaterials, demonstrating how data-driven approaches are increasingly used to predict antimicrobial activity, optimize synthesis parameters, model nanotoxicity, integrate multimodal datasets, and improve interpretability through explainable AI frameworks. Key findings indicate that machine learning-guided strategies and autonomous experimental platforms significantly accelerate material optimization while reducing reliance on traditional trial-and-error methods. The review further summarizes the performance and mechanisms of major antimicrobial nanomaterial systems, including metal and metal oxide nanoparticles, metal–organic frameworks, polymeric nanocarriers, nanoemulsions, and hybrid nanostructures, with emphasis on their translational applications in food preservation, antimicrobial coatings, wound healing, implant protection, and drug delivery. Despite these advances, challenges remain in data quality, model generalizability, toxicity prediction, reproducibility, and regulatory translation. AI-enabled and data-driven frameworks provide a powerful pathway for accelerating the rational design and practical implementation of next-generation antimicrobial nanomaterials. Full article

Machine Learning (ML) techniques are increasingly being adopted in particle accelerator operations to enable efficient control of complex systems. At INFN–LNL, we investigated both offline and real-time ML-driven approaches to enhance beam quality, reduce setup time, and improve reliability across different accelerator facilities. As part of this effort, we developed Adaptive Region Bayesian Optimization (ARBO), a custom Bayesian Optimization algorithm that dynamically expands its search domain when the predicted optimum approaches a boundary. Offline studies applied ARBO to the design optimization of the medium-energy beam transport line of the ANTHEM BNCT facility. Real-time online tests demonstrated the effectiveness of ARBO. At PIAVE–ALPI, the combined transmission improved from 44.2% to 52.6%, corresponding to an ALPI-only increase from approximately 69% to 82%, approaching the theoretical maximum of 93%. At the ESS normal-conducting linac, ARBO enabled the simultaneous tuning of more than 50 control elements while improving transmission and maintaining stable trajectory correction. These results indicate that adaptive optimization strategies can substantially improve accelerator performance and support future advances in ML-assisted accelerator operations. Full article

Pipes conveying fluids are important fluid–structure interaction systems encountered in aerospace, energy, marine, and industrial applications. Their dynamic behavior is strongly influenced by the interaction between structural motion and internal or external flow, leading to complex phenomena such as divergence, flutter, and flow-induced vibration. This review presents a comprehensive assessment of the dynamics and stability of pipes conveying fluids by integrating classical theories with recent developments in modeling, computation, materials, and control. The review covers mathematical formulations based on Euler–Bernoulli, Rayleigh, Timoshenko, and shell theories, together with analytical and numerical solution methods used for stability and vibration analysis. The effects of geometry, boundary conditions, flow configuration, damping, and material properties on dynamic response and instability thresholds are discussed. Special attention is given to composite, viscoelastic, functionally graded, and smart materials, as well as micro- and nanoscale pipe systems. Recent advances in vibration suppression, reduced-order modeling, machine learning, and physics-informed computational approaches are also reviewed. Finally, the paper identifies current challenges and future research directions, including multiphysics coupling, experimental validation, digital twins, and AI-assisted predictive modeling for fluid-conveying pipe systems. Full article

The optimisation design of agricultural machinery is shifting from offline, experience-driven engineering towards adaptive, data-driven, and closed-loop intelligent optimisation. Conventional approaches based on computer-aided engineering (CAE), empirical testing, mathematical modelling, and static multi-objective optimisation have provided an important engineering foundation, but they remain limited under unstructured field conditions involving soil heterogeneity, crop variability, climatic disturbance, and nonlinear machinery–environment interactions. This review systematically examines the evolution of intelligent optimisation design for agricultural machinery from conventional simulation-based methods to artificial intelligence (AI)- and digital twin (DT)-enabled paradigms. First, mathematical modelling, response surface methodology, discrete element method (DEM), computational fluid dynamics (CFD), multi-body dynamics (MBD), heuristic algorithms, and early AI-assisted surrogate optimisation are reviewed to clarify their contributions and limitations. Second, frontier enabling technologies are analysed, including agriculture-specific large models, generative AI, lightweight edge intelligence, deep reinforcement learning (DRL), embodied AI, federated learning (FL), and privacy-preserving computing. Third, system-level applications integrating DT and AI are discussed, with emphasis on full-lifecycle machinery optimisation, device–edge–cloud collaborative control, multi-agent fleet coordination, predictive maintenance, and Agriculture 5.0-oriented intelligent equipment systems. Key deployment bottlenecks are further identified, including sim-to-real inconsistency, virtual–physical mismatch in DTs, edge-side trade-offs among accuracy, latency, energy consumption, and cost, insufficient validation standards, and economic adoption barriers. Finally, a 2025–2030 roadmap is proposed, highlighting large-model–DT closed loops, control biomimetics, green low-carbon optimisation, and trustworthy human–machine symbiosis for sustainable Agriculture 5.0. Full article

Introduction: Accurate detection and characterization of intracardiac masses remain a major challenge in cardiovascular imaging due to overlapping morphological features between tumors, thrombi, and vegetations, as well as the inherent limitations of echocardiography, including operator dependency and variable image quality. Although echocardiography is the first-line imaging modality for evaluating cardiac masses, diagnostic uncertainty frequently necessitates additional multimodality imaging. Artificial intelligence (AI), including machine learning and deep learning approaches, has emerged as a promising strategy to improve image interpretation, automate feature extraction, and enhance diagnostic consistency. Objective: This narrative review aims to examine current advances in AI-enhanced echocardiography for cardiac tumor detection, with a particular focus on detection, segmentation, classification, multimodal integration, and clinical translation. Methods: A narrative literature review was conducted using PubMed, Scopus, and Google Scholar databases. Relevant English-language studies published between 2016 and 2026 were identified using keywords including “artificial intelligence”, “machine learning”, “deep learning”, “echocardiography”, “cardiac tumors”, “intracardiac masses”, “multimodal imaging”, and “ultrasomics”. Original studies, reviews, and methodological papers related to AI-assisted cardiovascular imaging were evaluated. Discussion: Current evidence suggests that AI-driven techniques, including radiomics (ultrasomics), convolutional neural networks, and multimodal learning frameworks, can improve the detection, segmentation, and classification of intracardiac masses. Experimental studies have reported high diagnostic performance, with some deep learning models achieving diagnostic accuracies exceeding 95% under controlled conditions. AI-assisted systems may also reduce interobserver variability and improve workflow efficiency. Multimodal AI approaches integrating echocardiography with cardiac magnetic resonance imaging, computed tomography, electrocardiography, and clinical data appear particularly promising for improving diagnostic discrimination. However, current models remain limited by small and imbalanced datasets, insufficient external validation, data heterogeneity, and limited generalizability across institutions and imaging protocols. Additional barriers to clinical implementation include annotation variability, limited interpretability of deep learning models, and regulatory considerations. Conclusions: AI-enhanced echocardiography has substantial potential to improve the detection and characterization of intracardiac masses by augmenting diagnostic consistency and supporting clinical decision-making. Nevertheless, current evidence remains largely based on retrospective and experimental studies. Future progress will depend on large multicenter collaborations, standardized imaging datasets, explainable AI frameworks, and prospective clinical validation to enable safe and effective integration into routine cardiovascular practice. Full article

Since the first successful synthesis of borophene in 2015, this atomically thin boron allotrope has attracted extensive attention due to its polymorphic structures, metallic conductivity, and outstanding mechanical flexibility. As a new member of the two-dimensional (2D) materials family, borophene exhibits a unique triangular lattice with tunable hexagonal vacancies, leading to rich structural diversity and anisotropic physical properties. Recent breakthroughs in synthesis—particularly molecular beam epitaxy (MBE), chemical vapor deposition (CVD), and solvothermal-assisted liquid-phase exfoliation (S-LPE)—have significantly expanded the accessible structural phases and improved control over film quality and stability. Meanwhile, borophene’s distinctive combination of structural and electronic characteristics has enabled its rapid development in both energy and biomedical applications. In energy storage, borophene serves as a promising anode material for lithium/sodium-ion batteries and a lightweight medium for hydrogen storage and supercapacitors, owing to its metallic conductivity, high surface charge density, and large adsorption capacity. In biomedicine, borophene-based nanoplatforms exhibit excellent photothermal conversion efficiency, enabling multifunctional roles in cancer diagnosis and therapy. Despite these advances, several challenges—such as environmental instability, oxidation susceptibility, and limited scalable synthesis—continue to restrict practical implementation. Future progress will depend on chemical functionalization, surface passivation, and machine-learning-assisted materials design to achieve oxidation-resistant, large-area, and biocompatible borophene derivatives. This review summarizes recent advances in borophene synthesis, structural engineering, and multifunctional applications, while outlining key scientific challenges and future opportunities for the realization of borophene-based materials in next-generation energy and biomedical systems. Full article

This paper presents a Digital Twin (DT)-based framework for the control, monitoring, and intelligent optimization of an Assembly/Disassembly/Repair Mechatronic Production Line (A/D/R MPL), developed as a laboratory platform aligned with Industry/Education 4.0/5.0 paradigms. The A/D/R MPL is assisted by two complementary cyber–physical robotic systems: an Assembly/Disassembly/Replacement Cyber–Physical Robotic System (A/D/R CPRS), and a Mobile Cyber–Physical Robotic System (MCPRS), enabling both fixed and mobile intelligent operations. The CPRS is equipped with an industrial robotic manipulator (IRM) responsible for A/D/R tasks, while the A/D Mechatronic Line (A/D ML) consists of seven interconnected workstations (WS1–WS7) dedicated to storage, transport, quality control, and final product handling. MCPRS includes a wheeled mobile robot (WMR), carrying a robotic manipulator (RM) and Mobile Visual Servoing System (MVSS). Each workstation is connected to a local slave programmable logic controller (PLC), which communicates via PROFIBUS with a master PLC located at the CPRS level. Additional communication infrastructures include LAN PROFINET and LAN Ethernet for local integration, and WAN Ethernet connectivity enabled through open platform Communication-Unified Architecture (OPC-UA), ensuring interoperability, scalability, and remote accessibility. Also, MODBUS TCP as serial industrial communication is used between the master PLC and the MCPRS. Virtual environment supports task planning through Augmented Reality (AR) and real-time monitoring through Virtual Reality (VR). The system behaviour is modelled with synchronized hybrid Petri Nets (SHPNs) which describe the discrete and hybrid dynamics of A/D/R processes. Artificial intelligence (AI) techniques are integrated into the DT framework for optimal task scheduling and adaptive decision-making. As a laboratory-scale implementation, the proposed system provides a comprehensive platform for experimentation, validation, and education. It supports Education 4.0/5.0 objectives by facilitating hands-on learning, human–machine interaction, and the integration of emerging technologies such as AI, Digital Twins, AR/VR, and cyber–physical systems. At the same time, it embodies Industry 4.0/5.0 principles, including interoperability, decentralization, sustainability, robustness, and human-centric design. Full article

Plastic design enables efficient structural systems by exploiting controlled inelastic deformation and force redistribution. While mature in steel structures due to stable ductility and well-defined yielding, its extension to reinforced concrete (RC) remains challenging because cracking, stiffness degradation, confinement dependency, and progressive damage govern deformation capacity and collapse mechanisms. This paper presents a state-of-the-art review of optimal plastic design methodologies for RC structures by tracing the evolution from classical plasticity theory to modern damage-informed, reliability-oriented, and sustainability-driven formulations. A systematic and structured literature review of more than 90 peer-reviewed journal articles (1990–2025) was conducted using Scopus, Web of Science, and ScienceDirect. The selected studies are classified by structural system type, plastic analysis approach, constitutive modeling strategy, and strengthening technique, including CFRP and hybrid fiber systems, optimization framework, and uncertainty treatment. The review highlights how nonlinear elasto-plastic and damage–plasticity models improve the prediction of plastic hinge development, redistribution, and failure-mode transitions, and how metaheuristic optimization, topology optimization, surrogate modeling, and machine learning are increasingly used to manage discrete design variables and computational cost. Reliability-based methods (e.g., FORM/SORM and simulation) are shown to be essential for quantifying deformation-capacity uncertainty and ensuring consistent collapse-prevention performance. A comparative assessment of nine plastic design methodologies is also provided, identifying their core assumptions, limitations, and domains of applicability within a structured evaluative framework. Remaining challenges include robust deformation-capacity prediction, reproducible calibration of damage models, and integration of life-cycle sustainability criteria within reliability-constrained plastic optimization. Future research directions are proposed toward multi-objective reliability-based design, durability-informed plastic modeling, and hybrid physics-informed AI-assisted workflows. Full article

This study quantified projection-dependent geometric distortion induced by vertical camera angulation in two-dimensional (2D) dental image acquisition and evaluated its implications for integration with three-dimensional (3D) CAD/CAM and artificial intelligence (AI)-driven workflows. To our knowledge, this study is among the first to use quantitative methods to characterize projection-induced distortion across the dental arch as a function of vertical camera angulation. Fourteen fully dentate casts were photographed at nine standardized vertical angulations using a controlled acquisition setup based on the standardized occlusal plane angle (SOPA). Tooth surface areas were measured through digital tracing and analyzed with a mixed-effects model (α = 0.05). Significant associations were identified between vertical camera angulation and measured tooth surface area for all teeth except canines (p < 0.05 for all except canines). Anterior teeth demonstrated increased apparent surface area at superior camera angulations, whereas posterior teeth were more prominently represented at inferior angulations. Central incisors, lateral incisors, and first premolars exhibited maximal visibility above the occlusal plane, while second premolars and molars were more optimally visualized below it. These findings indicate that vertical camera angulation induces non-uniform, region-specific geometric distortion across the dental arch. From a computational perspective, these distortions represent a systematic source of variability in 2D photographic datasets used in CAD/CAM workflows, virtual smile design, and AI-assisted image analysis. Because modern machine learning systems depend on geometrically consistent input data, uncorrected projection-induced distortion may reduce the reliability and generalizability of downstream algorithmic outputs. Accordingly, the present findings establish a quantitative basis for recognizing projection-induced variability in 2D dental photographs and support future development of geometry-aware calibration strategies for 2D-3D digital integration. AI-assisted correction represents a future translational direction contingent upon explicit alignment between acquisition geometry, image formation, and computational modeling. Full article

Artificial intelligence (AI) is reshaping medical rehabilitation by advancing from isolated assistive technologies toward data-driven program management. Beyond established applications in robotics and virtual reality, AI enables multimodal data integration, predictive analytics, adaptive therapy optimization, and real-time monitoring across rehabilitation domains. This review synthesizes 61 peer-reviewed studies to examine how AI supports the management, planning, and evaluation of rehabilitation programs. The evidence indicates strong technical maturity at the device and session levels, particularly in robotic control and wearable monitoring, whereas longitudinal program orchestration and system-level coordination remain at an emerging stage. Machine learning, reinforcement learning, computer vision, and time-series models facilitate patient phenotyping, therapy personalization, and prognostic modeling. However, their scalability is constrained by limited interoperability, heterogeneous outcome measures, and insufficient multicenter validation. A structured six-layer management architecture is proposed to conceptualize AI as an integrated orchestration framework. Advancing toward scalable and trustworthy rehabilitation ecosystems will require interoperable infrastructures, longitudinal validation, and embedded ethical and explainability mechanisms. Full article

Rapid and accurate pathogen detection serves as a core component in infectious disease prevention and control, clinical diagnosis and treatment, and public health surveillance systems. Although traditional detection methods have been widely adopted in clinical practice, they still exhibit significant limitations in terms of detection speed, throughput, automation levels, and adaptability to complex samples. In recent years, artificial intelligence (AI) technology has provided novel technical pathways for pathogen detection by leveraging its strengths in feature learning, pattern recognition, and multidimensional data modeling. The core contribution of this review lies in providing a novel, integrated analytical framework that overcomes the limitations of existing reviews, which often focus on a single modality (such as imaging alone or molecular diagnostics alone). Based on this framework, this paper systematically reviews AI research progress in pathogen detection, focusing on typical applications of machine learning and deep learning algorithms in analyzing imaging data, molecular diagnostic data, sensor signals, microscopic images, and multimodal data. It summarizes AI’s enabling value in enhancing detection sensitivity, specificity, automation, and point-of-care capabilities. Concurrently, this paper delves into key challenges facing AI-assisted pathogen detection, including data standardization, model generalization, interpretability, and clinical translation. It also outlines future trends toward intelligent, integrated, and clinically deployable applications. This paper aims to provide researchers and clinicians in the interdisciplinary field of artificial intelligence, biosensing, and clinical medicine with a comprehensive reference and roadmap for future development. Full article

As a common brain-computer interface (BCI) paradigm, electroencephalogram (EEG)-based motor imagery provides a critical pathway for both assistive technology to (restoring communication and control) and active rehabilitation (promoting neural plasticity and functional recovery). Domain adaptation has been shown to effectively enhance the decoding performance of motor intentions for target subjects by leveraging labeled data from source subjects. However, EEG data from source subjects often contains extensive personal privacy, and the direct access to source EEG data easily leads to privacy leakage issues. An important research topic is to achieve domain adaptation without directly accessing the source subjects’ raw data. To address this challenge, a privacy-preserving source-free domain adaptation framework, termed Transformer-based SFDA with Class-balanced Multicentric Dynamic Pseudo-labeling (T-CMDP), is proposed for cross-subject motor-imagery EEG classification. This framework consists of three coupled stages. In the source model training stage, a Transformer-based encoder combined with Riemannian manifold-aware feature extraction is employed to learn transferable and discriminative EEG feature representations. In the source-free target adaptation stage, only the pretrained source model is transferred to the target domain and adapted through knowledge distillation and information maximization, without accessing raw source EEG data. In the self-supervised learning stage, class-balanced multicentric prototypes and high-confidence pseudo-label updates are introduced to progressively refine the target-domain decision boundaries. Extensive experiments on three motor-imagery EEG datasets demonstrate that the proposed T-CMDP framework consistently outperforms eleven representative baselines from traditional machine learning, deep learning, and source-free transfer approaches, achieving average accuracies of 56.85%, 76.34%, and 74.49%, respectively. These results indicate that T-CMDP effectively alleviates inter-subject EEG distribution discrepancies and ensures the privacy preserving of source subjects, thereby facilitating more reliable and practical deployment of EEG-based BCI systems. Full article

The mechanical behavior of aqueduct structures exhibits highly complex characteristics during prestress tensioning, making it difficult for the traditional double-control method to accurately predict and real-time control the key stresses. To improve the construction safety of prestressed tensioning and the prediction accuracy of structural prestress responses, this study develops a rapid structural mechanical property prediction method based on machine learning. Taking prestressed aqueducts as the research object, a system of “finite element simulation—sample generation—machine learning prediction” is established. Firstly, multiple groups of tensioning parameter combinations are designed via Latin hypercube sampling, and the stress responses are obtained through finite element analysis to form a high-quality training sample library. Subsequently, critical structural features are extracted based on mesh reconstruction, and stress prediction models are established using the K-Nearest Neighbors (KNN) and Random Forest algorithms respectively; the prediction performance of both models is compared and validated against finite element simulation results. Furthermore, the prediction outputs of the optimal machine learning model were used to analyze the stress distribution and potential stress concentration issues of the structure during the tensioning process. The comparative analysis results indicate that the Random Forest model performs best in terms of stress prediction accuracy and stability, and its prediction results are highly consistent with those of the finite element method. Compared with traditional finite element condition analysis, the machine learning model can complete multi-condition stress prediction in a shorter time. Leveraging its high-efficiency prediction capability, local high-stress areas of the structure in the tensioning construction scheme can be identified, thereby providing effective optimization schemes to improve the stress distribution. The mechanical response prediction method for the prestress tensioning process of aqueducts, with machine learning as the core, constructed in this paper realizes the rapid and reliable prediction of key stresses throughout the entire prestress tensioning process. This method can be applied to assist in optimizing tensioning construction schemes and construction monitoring, providing a practical technical solution for safety control of aqueduct structures during the prestress construction stage. Full article