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26 pages, 3281 KB  
Article
Canonical Analysis of the Impact of Climate Predictors on Sugarcane Yield in the Eastern Region of Pernambuco, Brazil
by Rodrigo Rogério da Silva, Geber Barbosa de Albuquerque Moura, Pabrício Marcos Oliveira Lopes, Cristina Rodrigues Nascimento and Pedro Rogério Giongo
Agriculture 2025, 15(20), 2162; https://doi.org/10.3390/agriculture15202162 (registering DOI) - 18 Oct 2025
Abstract
Sugarcane yield plays a crucial role in food safety and biofuel production, and it is strongly influenced by climatic variations. In this context, this study applies canonical correlation analysis (CCA) to identify the climatic predictors, such as sea surface temperature, atmospheric pressure, and [...] Read more.
Sugarcane yield plays a crucial role in food safety and biofuel production, and it is strongly influenced by climatic variations. In this context, this study applies canonical correlation analysis (CCA) to identify the climatic predictors, such as sea surface temperature, atmospheric pressure, and wind speed, that affect sugarcane yield from 1990 to 2019. Hierarchical cluster analysis applied to the performance of 58 municipalities in the eastern region of Pernambuco identified three distinct and homogeneous groups. An analysis of the CCA for the three sugarcane yield groups and climatic variables revealed that the first canonical function was significant with R = 0.82 and precision of 0.67 (p ≤ 0.05 at 95% confidence level), and that the sugarcane yield groups and climatic variables were different (Wilks’ lambda = 0.14), but they were associated. Climatic variables affected the three sugarcane productivity groups, with redundancy indices of 29.7%, 52.2%, and 59.9%. Climatic variables with positive canonical weights enhance performance, while those with negative weights decrease yields. The structural canonical loads and cross-loadings reveal that sea surface temperature plays a crucial role in determining sugarcane yield, potentially influencing precipitation and temperature patterns in the region. The sensitivity analysis confirms the stability of the canonical loads and the robustness of the results, demonstrating that this research can support yield forecasting, regional agricultural policy, and drought management. Identifying climate predictors, such as sea surface temperature, wind speed, and atmospheric pressure, enables the creation of accurate models to predict sugarcane productivity, assisting farmers in planning input management, irrigation during dry periods, and harvesting. Furthermore, climate data can inform policies that encourage sustainable agricultural practices and adaptation to climate conditions, strengthening food security and guiding the selection of more resilient sugarcane varieties, increasing production resilience. Full article
(This article belongs to the Section Ecosystem, Environment and Climate Change in Agriculture)
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15 pages, 2951 KB  
Article
Urban–Rural PM2.5 Dynamics in Kraków, Poland: Patterns and Source Attribution
by Dorota Lipiec, Piotr Lipiec and Tomasz Danek
Atmosphere 2025, 16(10), 1201; https://doi.org/10.3390/atmos16101201 - 17 Oct 2025
Abstract
Hourly PM2.5 concentrations were measured from February to May 2025 by a network of low-cost sensors located in urban Kraków and its surrounding municipalities. Temporal variability associated with the transition from the heating period to the spring months, together with spatial contrasts, [...] Read more.
Hourly PM2.5 concentrations were measured from February to May 2025 by a network of low-cost sensors located in urban Kraków and its surrounding municipalities. Temporal variability associated with the transition from the heating period to the spring months, together with spatial contrasts, were assessed with principal component analysis (PCA), urban–rural difference curves, and a detailed examination of the most severe smog episode (12–13 February). Particle trajectories generated with the HYSPLIT dispersion model, run in a coarse-grained, 36-task parallel configuration, were combined with kernel density mapping to trace emission pathways. The results show that peak concentrations coincide with the heating season; rural sites recorded higher amplitudes and led the urban signal by up to several hours, implicating external sources. Time-series patterns, PCA loadings, and HYSPLIT density fields provided mutually consistent evidence of pollutant advection toward the city. Parallelizing HYSPLIT on nine central processing unit (CPU) cores reduced the runtime from more than 600 s to about 100 s (speed-up ≈ 6.5), demonstrating that routine episode-scale analyses are feasible even on modest hardware. The findings underline the need to extend monitoring and mitigation beyond Kraków’s administrative boundary and confirm that coarse-grained parallel HYSPLIT modeling, combined with low-cost sensor data and relatively basic statistics, offers a practical framework for rapid source attribution. Full article
(This article belongs to the Special Issue High-Performance Computing for Atmospheric Modeling (2nd Edition))
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19 pages, 4118 KB  
Article
Evaluating Reticulorumen Temperature, Rumination, Activity and pH Measured by Rumen Sensors as Indicators of Heat Load in Fattening Bulls
by Kay Fromm, Christian Ammon, Thomas Amon and Gundula Hoffmann
Sensors 2025, 25(20), 6401; https://doi.org/10.3390/s25206401 - 16 Oct 2025
Abstract
The aim of this experiment was to determine whether reticulorumen temperature (ReT), rumination, activity or pH captured by a rumen sensor bolus system (smaXtec animal care GmbH, Graz, Austria) can be used as an early indicator of heat load (HL) and to assess [...] Read more.
The aim of this experiment was to determine whether reticulorumen temperature (ReT), rumination, activity or pH captured by a rumen sensor bolus system (smaXtec animal care GmbH, Graz, Austria) can be used as an early indicator of heat load (HL) and to assess how its daily patterns are influenced by diurnal effects. Physiological and behavioral data from 70 male feedlot cattle (Uckermärker, Hereford, Simmentaler) housed in a closed barn were investigated using the calculated temperature-humidity index (THI) from remote HOBO Onset climate sensors over a period of 210 days. Using time series analysis and seasonal ARIMA modeling, it was found that ReT followed the same patterns throughout days with a THI < 74 as well as days under heat load conditions. Time series and correlation analyses were also performed for the rumen pH, rumination index and activity index. The collective mean ReT over the winter days assessed (n = 14,971) was 39.48 °C, with a minimum mean of 38.31 °C and a maximum mean of 40.69 °C. In comparison, the collective mean ReT over the summer days assessed (n = 14,030) was 39.53 °C, with a minimum mean of 38.39 °C and a maximum mean of 42.02 °C. Pearson’s correlation did not reveal a relationship between THI and ReT (r = −0.06; p < 0.001) and only minimally for rumination (r = −0.11; p < 0.001). Rumination clearly decreased with increasing ambient temperature in comparison to days with a THI < 74. A long-term effect is also visible when the monthly mean rumination from all bulls tends to decrease slightly from February to May and then increases beginning in June. The mean pH values decreased throughout the summer months. Nevertheless, the comparison between daily fluctuations in pH values under HL failed to yield significant deviations from those captured on days of winter. The Pearson correlation for rumen pH showed a weak negative linear relationship with THI (r = −0.3; p < 0.001). The monthly means of the motion activity index could also not verify that HL led to increasing activity (Pearson correlation for motion activity and THI: r = 0.04; p < 0.001). The heat load had no visible short-term effects on the ReT or rumen pH, but rumination and peak motion activity were reduced on days with high ambient temperatures. Full article
(This article belongs to the Section Biomedical Sensors)
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12 pages, 867 KB  
Article
Gestational Diabetes Mellitus Subtypes Derived by Clustering Analysis Show Heterogeneity in Glucometabolic Parameters Already at Early Pregnancy
by Grammata Kotzaeridi, Benedetta Salvatori, Agnese Piersanti, Florian Heinzl, Sophie Zarotti, Herbert Kiss, Silke Wegener, Iris Dressler-Steinbach, Wolfgang Henrich, Micaela Morettini, Andrea Tura and Christian S. Göbl
Nutrients 2025, 17(20), 3252; https://doi.org/10.3390/nu17203252 - 16 Oct 2025
Abstract
Background/Objectives: The classification of patients with diabetes into phenotypes with distinct risks and therapeutic needs is crucial for individualized care. We recently introduced a clustering model for gestational diabetes mellitus (GDM). This study aims to further characterize the proposed clusters and to identify [...] Read more.
Background/Objectives: The classification of patients with diabetes into phenotypes with distinct risks and therapeutic needs is crucial for individualized care. We recently introduced a clustering model for gestational diabetes mellitus (GDM). This study aims to further characterize the proposed clusters and to identify cluster-specific differences in glucometabolic parameters during early pregnancy in an independent cohort. The metabolic profiles and dietary habits of GDM clusters will be compared with those of a normal glucose-tolerant (NGT) control group. Methods: 1088 women (195 who developed GDM and 893 who remained NGT) underwent a broad risk evaluation at early pregnancy. GDM patients were further categorized into the three proposed GDM subtypes (CL1 to CL3). Results: Among GDM patients, 7.7% were classified as CL1, 35.9% as CL2, and 56.4% as CL3. CL1 showed higher age, pregestational BMI, and increased glucose concentrations both at fasting and during the diagnostic oral glucose tolerance test. CL2 was characterized by elevated BMI and fasting glucose, while CL3 showed higher glucose concentrations after the oral glucose load, with BMI levels comparable to NGT mothers. Women in the CL1 group exhibited impaired insulin sensitivity and β-cell function at early pregnancy and showed elevated lipid levels. Compared to NGT women, a positive family history of diabetes was more prevalent in CL1 and CL3, but not in CL2. Dietary patterns were similar across all groups. Conclusions: Our study showed distinct alterations in glucometabolic parameters already at early pregnancy among GDM subtypes. Patients in CL1 exhibited the most unfavorable risk constellation and could benefit from lifestyle changes and nutrition therapy in early pregnancy, despite showing similar dietary patterns as the NGT group. Full article
(This article belongs to the Section Nutrition in Women)
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18 pages, 4462 KB  
Article
Finite Element Modelling Approaches for Assessing Column Stability in Heritage Structures: A Case Study of the Mosque–Cathedral of Córdoba
by Maria-Victoria Requena-Garcia-Cruz, Jose-Carlos Gómez-Sánchez, Isabel Gónzalez-de-León and Antonio Morales-Esteban
Modelling 2025, 6(4), 130; https://doi.org/10.3390/modelling6040130 - 16 Oct 2025
Abstract
This study has investigated the structural and seismic performance of monolithic stone columns in the historical Mosque–Cathedral of Córdoba, with a focus on the earliest section constructed during the reign of Abd al-Rahman I (VIII century). An advanced 3D finite element (FE) model [...] Read more.
This study has investigated the structural and seismic performance of monolithic stone columns in the historical Mosque–Cathedral of Córdoba, with a focus on the earliest section constructed during the reign of Abd al-Rahman I (VIII century). An advanced 3D finite element (FE) model has been developed to assess the effects of geometric imperfections and component interactions on the stability of columns under both vertical and horizontal static loading. Three distinct modelling strategies have been employed in OpenSees 3.7.1, incorporating column inclination and contact elements to simulate mortar interfaces. Material properties have been calibrated using experimental data and in situ observations. The gravitational analysis has shown no significant damage in any of the configurations, aligning with the observed undamaged state of the structure. Conversely, horizontal analyses have revealed that tensile damage has predominantly occurred at the lower shaft. The inclusion of contact elements has led to a significant reduction in lateral resistance, highlighting the importance of accounting for friction and interface behaviour. Column inclination has been found to have a significant influence on failure patterns. These findings have highlighted the critical role of detailed modelling in evaluating structural vulnerabilities. Such features are generally included in the numerical modelling and evaluation of heritage buildings. Consequently, they can contribute to a better understanding of the seismic behaviour of historic masonry structures. Full article
(This article belongs to the Section Modelling in Engineering Structures)
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17 pages, 2172 KB  
Article
Brain Booster Buildings: Modelling Stairs’ Use as a Daily Booster of Brain-Derived Neurotrophic Factor
by Mohamed Hesham Khalil and Koen Steemers
Buildings 2025, 15(20), 3730; https://doi.org/10.3390/buildings15203730 - 16 Oct 2025
Abstract
This paper establishes the Brain Booster Buildings framework, the first model to demonstrate how daily stair use can elevate brain-derived neurotrophic factor (BDNF), a vital molecule for lifelong neurogenesis and brain health in humans. Through a novel framework of the associations between metabolic [...] Read more.
This paper establishes the Brain Booster Buildings framework, the first model to demonstrate how daily stair use can elevate brain-derived neurotrophic factor (BDNF), a vital molecule for lifelong neurogenesis and brain health in humans. Through a novel framework of the associations between metabolic equivalents (METs) data and BDNF response studies, we establish that stairs are generally higher in METs than any indoor activity. We further explain how architectural parameters (riser height, floor number, pace) predictably modulate exercise intensity during stair use. We identify two implementable patterns: moderate-intensity continuous use (≥20 min, 1–3 floors) and high-intensity interval training (6 min, carrying loads while using stairs in a building with three floors or less, or using stairs in a building with ≥3 floors, load-free). Based on BDNF responses to comparable exercise intensities, 6 min of high-intensity stair climbing is predicted to increase serum BDNF by up to 40%. Since people spend ~90% of their time indoors while neurogenesis declines fourfold throughout the adult lifespan, affecting mood, stress resilience, and memory, vertical architecture emerges as a vital, accessible, and cost-effective infrastructure that boosts BDNF for neurogenesis, plasticity, and brain health. We conducted scenario-based modelling using the Brain Booster Buildings framework to estimate how the use of stairs in residential, office, educational, hospital, and commercial buildings may boost BDNF levels based on established intensity–BDNF relationships. The framework provides architects, policymakers, and clinicians with evidence-based estimated specifications to use buildings as daily brain boosters. Full article
(This article belongs to the Special Issue BioCognitive Architectural Design)
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21 pages, 2429 KB  
Article
Visualizing Spatial Cognition for Wayfinding Design: Examining Gaze Behaviors Using Mobile Eye Tracking in Counseling Service Settings
by Jain Kwon, Alea Schmidt, Chenyi Luo, Eunwoo Jun and Karina Martinez
ISPRS Int. J. Geo-Inf. 2025, 14(10), 406; https://doi.org/10.3390/ijgi14100406 - 16 Oct 2025
Abstract
Wayfinding with minimal effort is essential for reducing cognitive load and emotional stress in unfamiliar environments. This exploratory quasi-experimental study investigated wayfinding challenges in a university building housing three spatially dispersed counseling centers and three academic departments that share the building entrances, lobby, [...] Read more.
Wayfinding with minimal effort is essential for reducing cognitive load and emotional stress in unfamiliar environments. This exploratory quasi-experimental study investigated wayfinding challenges in a university building housing three spatially dispersed counseling centers and three academic departments that share the building entrances, lobby, and hallways. Using mobile eye tracking with concurrent think-aloud protocols and schematic mapping, we examined visual attention patterns during predefined navigation tasks performed by 24 first-time visitors. Findings revealed frequent fixations on non-informative structural features, while existing wayfinding cues were often overlooked. High rates of null gazes indicated unsuccessful visual searching. Thematic analysis of verbal data identified eight key issues, including spatial confusion, aesthetic monotony, and inadequate signage. Participants frequently described the environment as disorienting and emotionally taxing, comparing it to institutional settings such as hospitals. In response, we developed wayfinding design proposals informed by our research findings, stakeholder needs, and contextual priorities. We used an experiential digital twin that prioritized perceptual fidelity to analyze the current wayfinding challenges, develop experimental protocols, and discuss design options and costs. This study offers a transferable methodological framework for identifying wayfinding challenges through convergent analysis of gaze patterns and verbal protocols, demonstrating how empirical findings can inform targeted wayfinding design interventions. Full article
(This article belongs to the Special Issue Indoor Mobile Mapping and Location-Based Knowledge Services)
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21 pages, 1663 KB  
Article
Neuromechanical Effects of Eccentric–Reactive Training on Explosiveness, Asymmetry, and Stretch-Shortening in Elite Table Tennis Players
by Kinga Wiktoria Łosińska, Artur Gołaś, Florentyna Tyrała, Monika Szot and Adam Maszczyk
Biomechanics 2025, 5(4), 84; https://doi.org/10.3390/biomechanics5040084 - 16 Oct 2025
Viewed by 67
Abstract
Background/Objectives: This study examined the effects of a six-week eccentric–reactive training program on neuromechanical markers of lateral explosiveness, asymmetry, and stretch-shortening cycle (SSC) efficiency in elite male youth table tennis players. Fourteen national-level athletes (mean age = 16.6 years) were assigned to [...] Read more.
Background/Objectives: This study examined the effects of a six-week eccentric–reactive training program on neuromechanical markers of lateral explosiveness, asymmetry, and stretch-shortening cycle (SSC) efficiency in elite male youth table tennis players. Fourteen national-level athletes (mean age = 16.6 years) were assigned to either an experimental group (EG, n = 7) or a control group (CG, n = 7). EG performed flywheel squats and lateral depth jumps three times per week, while CG maintained regular training. Pre- and post-intervention testing included countermovement jumps, reactive strength index (RSI_DJ), force asymmetry, time-to-stabilization, SSC efficiency, and energy transfer ratio (ETR), measured via force plates, EMG, and inertial sensors. Methods: Multi-dimensional statistical analysis revealed coordinated improvements in explosive power and movement efficiency following eccentric training that were not visible when examining individual measures separately. Athletes in the training group showed enhanced neuromechanical control and developed more efficient movement patterns compared to controls. The analysis successfully identified distinct performance profiles and demonstrated that the training program improved explosive characteristics in elite table tennis players. Results: Univariate ANOVAs showed no significant Group × Time effects for RSI_DJ, ETR, or SSC_Eff, although RSI_DJ displayed a moderate effect size in EG (d = 0.47, 95% CI [0.12, 0.82], p = 0.043). In contrast, MANOVA confirmed a significant multivariate Group × Time interaction (p = 0.013), demonstrating integrated neuromechanical adaptations. Regression analysis indicated lower baseline CMJ and RSI_DJ predicted greater RSI improvements. Conclusions: In conclusion, eccentric–reactive training promoted multidimensional neuromechanical adaptations in elite racket sport athletes, supporting the use of integrated monitoring and targeted eccentric loading to enhance lateral explosiveness and efficiency. Full article
(This article belongs to the Section Neuromechanics)
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19 pages, 14851 KB  
Article
Investigation on the Evolution Mechanism of the Mechanical Performance of Road Tunnel Linings Under Reinforcement Corrosion
by Jianyu Hong, Xuezeng Liu, Dexing Wu and Jiahui Fu
Buildings 2025, 15(20), 3723; https://doi.org/10.3390/buildings15203723 - 16 Oct 2025
Viewed by 59
Abstract
To clarify the influence of reinforcement corrosion on the mechanical performance of road tunnel linings, localized tests on reinforcement-induced concrete expansion are conducted to identify cracking patterns and their effects on load-bearing behavior. Refined three-dimensional finite element models of localized concrete and the [...] Read more.
To clarify the influence of reinforcement corrosion on the mechanical performance of road tunnel linings, localized tests on reinforcement-induced concrete expansion are conducted to identify cracking patterns and their effects on load-bearing behavior. Refined three-dimensional finite element models of localized concrete and the entire tunnel are developed using the concrete damaged plasticity model and the extended finite element method and validated against experimental results. The mechanical response and crack evolution of the lining under corrosion are analyzed. Results show that in single-reinforcement specimens, cracks propagate perpendicular to the reinforcement axis, whereas in multiple-reinforcement specimens, interacting cracks coalesce to form a π-shaped pattern. The cover-layer crack width exhibits a linear relationship with the corrosion rate. Corrosion leads to a reduction in the stiffness and load-bearing capacity of the local concrete. At the tunnel scale, however, its influence remains highly localized, and the additional deflection exhibits little correlation with the initial deflection. Local corrosion causes a decrease in bending moment and an increase in axial force in adjacent linings; when the corrosion rate exceeds about 15%, stiffness damage and internal force distribution tend to stabilize. Damage and cracks initiate around corroded reinforcement holes, extend toward the cover layer, and connect longitudinally, forming potential spalling zones. Full article
(This article belongs to the Section Building Structures)
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19 pages, 2442 KB  
Article
Spatiotemporal Evolution and Integrated Risk Assessment of Potentially Toxic Element Pollution in Coastal Waters: A Case Study of Bohai Bay Cases in China
by Limei Qu, Jianbiao Peng, Pifu Cong and Yanan Huang
Toxics 2025, 13(10), 880; https://doi.org/10.3390/toxics13100880 - 15 Oct 2025
Viewed by 216
Abstract
Under the increasing pressures of land-based pollution and intensive coastal development, marine ecosystems are facing unprecedented challenges, highlighting the urgent need for enhanced protection and management of marine environmental quality. This study examines the spatiotemporal distribution and pollution risks of seven potentially toxic [...] Read more.
Under the increasing pressures of land-based pollution and intensive coastal development, marine ecosystems are facing unprecedented challenges, highlighting the urgent need for enhanced protection and management of marine environmental quality. This study examines the spatiotemporal distribution and pollution risks of seven potentially toxic elements (Hg, Cd, Pb, Cr, As, Zn, and Cu) in the coastal waters of Bohai Bay, China, based on monitoring data collected from 2020 to 2023. Results show a significant decline in annual average concentrations of Pb (from 3.23 ± 1.11 μg/L to 0.10 ± 0.06 μg/L) and Hg (from 0.05 ± 0.02 μg/L to 0.01 ± 0.00 μg/L), reflecting effective pollution control measures. In contrast, Cu concentrations nearly doubled, rising from 0.90 ± 0.50 μg/L in 2020 to 1.98 ± 0.42 μg/L in 2023, while Zn exhibited a “V”-shaped fluctuation over the study period. Spatially, Zn, Pb, and Hg displayed pronounced clustering patterns, with coefficients of variation (CV) of 1.04, 1.49, and 1.17, respectively. The Pollution Load Index (PLI) decreased from 1.82 in 2020 to 0.94 in 2023, indicating an overall improvement in ecological quality. However, the Risk Index (RI) reached a maximum of 672.5 at Site 11 in 2020, with Hg and Cd contributing 49.6% and 22.7% to the total risk, respectively. Health risk assessment revealed non-carcinogenic risks (Hi) below the safety threshold (Hi < 1) across all sites. In contrast, carcinogenic risks (CR) ranged from 5.7 × 10−4 to 9.1 × 10−4, approaching the acceptable upper limit of 10−3, primarily due to dermal exposure to Hg and the high toxicity of Cd. Principal Component Analysis (PCA) suggested familiar sources for Hg, Pb, and Zn, whereas As appeared to originate from distinct pathways. Overall, this study establishes an integrated “pollution–ecological–health” assessment framework, offering scientific support for targeted pollution prevention and zonal management strategies in coastal environments. Full article
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15 pages, 1863 KB  
Article
Energy Dissipation and Damage Evolution of Water-Saturated Skarn Under Impact Loading
by Ximing Jian, Pinzhe Zhao, Xianglong Li, Jianguo Wang, Yaohong Li and Yang Yang
Appl. Sci. 2025, 15(20), 11040; https://doi.org/10.3390/app152011040 - 15 Oct 2025
Viewed by 159
Abstract
Understanding the combined effects of water and dynamic disturbance on rock behavior is essential for deep underground engineering, where groundwater and blasting often coexist. Existing studies have mainly emphasized static weakening by water or the strength characteristics under impact, while the energy evolution [...] Read more.
Understanding the combined effects of water and dynamic disturbance on rock behavior is essential for deep underground engineering, where groundwater and blasting often coexist. Existing studies have mainly emphasized static weakening by water or the strength characteristics under impact, while the energy evolution process remains insufficiently addressed. To fill this gap, uniaxial impact compression tests were conducted on dry and water-saturated skarn specimens using a separated Split Hopkinson Pressure Bar system. The relationship between peak stress and impact pressure was analyzed, and the total input energy, releasable elastic strain energy, and dissipated energy were quantified to examine their evolution with strain. The results indicate that water saturation significantly reduces dynamic strength and modifies the damage process. During the compaction and elastic stages, dissipated energy is low but slightly higher in water-saturated specimens due to microcrack initiation. In the plastic stage, dry specimens exhibit faster energy dissipation, while water-saturated specimens show reduced capacity for crack propagation dissipation. Damage–strain curves follow an S-shaped pattern, with water-saturated specimens presenting higher damage growth rates in the plastic stage. These findings clarify the energy-based damage mechanisms of skarn under impact loading and provide theoretical support for evaluating stability in water-rich underground environments. Full article
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13 pages, 1847 KB  
Article
Alterations in Static Plantar Pressure Before and After Total Knee Arthroplasty in Individuals with Knee Osteoarthritis
by Saidan Shetty, G Arun Maiya, Mohandas Rao KG, Sandeep Vijayan, Shetty Shrija Jaya and Bincy M George
Prosthesis 2025, 7(5), 128; https://doi.org/10.3390/prosthesis7050128 - 15 Oct 2025
Viewed by 190
Abstract
Background/Objectives: Knee osteoarthritis (OA) alters lower limb biomechanics, often leading to an asymmetric plantar pressure distribution. Total knee arthroplasty (TKA) aims to restore joint function and may normalize plantar loading, but evidence from instrumented static pressure analysis is limited. The objective of this [...] Read more.
Background/Objectives: Knee osteoarthritis (OA) alters lower limb biomechanics, often leading to an asymmetric plantar pressure distribution. Total knee arthroplasty (TKA) aims to restore joint function and may normalize plantar loading, but evidence from instrumented static pressure analysis is limited. The objective of this study was to compare static plantar pressure distributions before and after TKA in individuals with knee OA and in age- and sex-matched healthy controls. Methods: A pre-post study was conducted on 77 individuals with severe knee OA (Kellgren–Lawrence grade 4) who underwent TKA and 77 matched healthy controls. The plantar pressure area, average pressure, and maximal pressure were assessed preoperatively and at 6 and 12 months postoperatively using a Win-Track force platform. Standard postoperative rehabilitation was followed. Statistical analyses included independent t-tests and repeated-measures ANOVA (p ≤ 0.05). Results: Compared with controls, pre-TKA patients presented significantly lower plantar pressure area, average pressure, and maximal pressure than controls (p < 0.001). At 6 and 12 months post-TKA, the plantar pressure area (p < 0.001) and average pressure (p = 0.001) improved significantly, with more balanced bilateral loading and increased forefoot weight transfer. At 12 months, no significant differences in any plantar pressure parameters remained between the TKA and control groups. Conclusions: Severe knee OA is associated with altered static plantar pressure patterns, characterized by reduced loading and asymmetry. TKA effectively restores plantar pressure distribution, achieving normalization within 12 months. The incorporation of plantar pressure assessment into pre- and postoperative care may guide targeted rehabilitation and enhance functional recovery. Full article
(This article belongs to the Section Orthopedics and Rehabilitation)
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16 pages, 250 KB  
Article
Behavioral Predictors of Intentional and Unintentional Nonadherence to Antiretroviral Therapy and Their Implications for Virological Failure Among People with HIV in Taiwan
by Su-Han Hsu, Chien-Chun Wang, Yung-Feng Yen, Tsen-Fang Yen, Po-Tsen Yeh and Hsin-Hao Lai
Viruses 2025, 17(10), 1375; https://doi.org/10.3390/v17101375 - 14 Oct 2025
Viewed by 356
Abstract
Adherence to antiretroviral therapy (ART) is critical for HIV management and sustained virological suppression. Differentiating intentional from unintentional nonadherence is essential for developing tailored interventions, yet evidence from Asian populations remains limited. A cross-sectional study of 846 people with HIV (PWH) in northern [...] Read more.
Adherence to antiretroviral therapy (ART) is critical for HIV management and sustained virological suppression. Differentiating intentional from unintentional nonadherence is essential for developing tailored interventions, yet evidence from Asian populations remains limited. A cross-sectional study of 846 people with HIV (PWH) in northern Taiwan assessed ART adherence using the MARS-5 scale. Participants were categorized into good, unintentional, or intentional non-adherence groups. Logistic regression identified associated behavioral and psychosocial factors. Recreational drug use and younger age were independently linked to both unintentional and intentional poor adherence. Higher income and the use of single-tablet regimens were protective against intentional nonadherence, whereas disclosure of HIV status to a partner and an unsuppressed viral load were significantly associated with intentional nonadherence. Reported reasons included being too busy, emotional distress, and running out of medication. These findings suggest that intentional and unintentional nonadherence represent distinct behavioral patterns, with intentional lapses more strongly linked to virological failure. Addressing substance use, simplifying regimens, and providing psychosocial support after disclosure are essential to optimize adherence and achieve UNAIDS 2030 targets. Full article
32 pages, 9478 KB  
Article
Numerical Simulation Study on the Energy Benefits and Environmental Impacts of BIPV Installation Configurations and Positions at the Street Canyon Scale
by Minghua Huang, Kuan Chen, Fangxiong Wang and Junhui Liao
Buildings 2025, 15(20), 3692; https://doi.org/10.3390/buildings15203692 - 14 Oct 2025
Viewed by 185
Abstract
Building-integrated photovoltaic (BIPV) systems play a pivotal role in advancing low-carbon urban transformation. However, replacing conventional building envelope materials with photovoltaic (PV) panels modifies heat transfer processes and airflow patterns, potentially influencing urban environmental quality. This study examines the impacts of BIPV on [...] Read more.
Building-integrated photovoltaic (BIPV) systems play a pivotal role in advancing low-carbon urban transformation. However, replacing conventional building envelope materials with photovoltaic (PV) panels modifies heat transfer processes and airflow patterns, potentially influencing urban environmental quality. This study examines the impacts of BIPV on building energy efficiency, PV system performance, and street canyon micro-climates, including airflow, temperature distribution, and pollutant dispersion, under perpendicular wind speeds ranging from 0.5 to 4 m/s, across three installation configurations and three installation positions. Results indicate that rooftop PV panels outperform facade-mounted systems in power generation. Ventilated PV configurations achieve optimal energy production and thermal insulation, thereby reducing building cooling loads and associated electricity consumption. Moreover, BIPV installations enhance street canyon ventilation, improving pollutant removal rates: ventilation rates increased by 1.43 times (rooftop), 3.02 times (leeward facade), and 2.09 times (windward facade) at 0.5 m/s. Correspondingly, canyon-averaged pollutant concentrations decreased by 30.1%, 87.7%, and 85.9%, respectively. However, the introduction of facade PV panels locally reduces pedestrian thermal comfort, particularly under low wind conditions, but this negative effect is significantly alleviated with increasing wind speed. To quantitatively evaluate BIPV-induced micro-climatic impacts, this study introduces the Pollutant-Weighted Air Exchange Rate (PACH)—a metric that weights the air exchange rate by pollutant concentration—providing a more precise indicator for evaluating micro-environmental changes. These findings offer quantitative evidence to guide urban-scale BIPV deployment, supporting the integration of renewable energy systems into sustainable urban design. Full article
(This article belongs to the Section Building Energy, Physics, Environment, and Systems)
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17 pages, 1191 KB  
Article
Psychopathological Risk During Adolescent Study-Abroad: A Larger-Cohort Update of a Previous Longitudinal Study
by Silvia Cimino and Luca Cerniglia
Eur. J. Investig. Health Psychol. Educ. 2025, 15(10), 210; https://doi.org/10.3390/ejihpe15100210 - 14 Oct 2025
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Abstract
This article updates and extends a prior longitudinal study on adolescents’ psychological adjustment during short-term study-abroad programs, analyzing a newly collected larger cohort with the same design and measures. Using the same assessment schedule (pre-departure, mid-sojourn, post-return) with a larger cohort, we confirmed [...] Read more.
This article updates and extends a prior longitudinal study on adolescents’ psychological adjustment during short-term study-abroad programs, analyzing a newly collected larger cohort with the same design and measures. Using the same assessment schedule (pre-departure, mid-sojourn, post-return) with a larger cohort, we confirmed the adequate reliability and longitudinal comparability of the Teacher’s Report Form. Mean-level analyses replicated earlier patterns: internalizing symptoms increased during the sojourn and remained elevated at reentry, whereas externalizing problems followed an inverted-U, rising abroad and returning to baseline after return. Person-centered models identified three trajectory classes for both domains: a low-stable group, a transient-elevated group showing a mid-sojourn spike with subsequent recovery, and a small high-persistent group with enduring elevations. Clinical threshold transitions showed a temporary mid-sojourn rise in borderline/clinical cases for both domains, with partial normalization after return. Reliable-change estimates further distinguished transient from sustained change. Together, the findings characterize studying abroad as a moderate, time-bound stressor for most adolescents, with a minority at persistent risk. The implications of these findings include suggestions for front-loaded and reentry supports, pre-departure screening, and targeted mid-sojourn monitoring. The strengths include longitudinal measurement invariance and person-centered modeling; the limitations include teacher-only reports and a short post-return follow-up. Full article
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