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33 pages, 1059 KB  
Review
Pulses and Cancer Outcomes: A Scoping Review of Human Studies on Risk Reduction
by Mohd Naeem Mohd Nawi, Nurliayana Ibrahim, Tay Bee Yong, Aswir Abd Rashed and Vimala R.M. T. Balasubramaniam
Nutrients 2026, 18(13), 2064; https://doi.org/10.3390/nu18132064 (registering DOI) - 24 Jun 2026
Abstract
Background/Objectives: Pulses are nutrient-dense, low-glycaemic legumes rich in fibre and bioactive compounds that may modulate carcinogenesis through effects on diet quality, metabolism, and the gut microbiome. This scoping review mapped human evidence on pulses in relation to cancer risk reduction and related [...] Read more.
Background/Objectives: Pulses are nutrient-dense, low-glycaemic legumes rich in fibre and bioactive compounds that may modulate carcinogenesis through effects on diet quality, metabolism, and the gut microbiome. This scoping review mapped human evidence on pulses in relation to cancer risk reduction and related mechanistic and survivorship-relevant outcomes. Methods: Following the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) and Joanna Briggs Institute (JBI) Population, Concept and Context (PCC) guidance, we searched CENTRAL, Scopus and PubMed (2014–31 December 2025), supplemented by backward and forward citation tracking, for English-language human studies in which pulses were a defined exposure or intervention and cancer-specific clinical outcomes or biomarkers were reported. Exposures are described using the original ‘legume’ terminology, with pulse-specific interpretation restricted to FAO-defined pulses or clearly dry pulse forms and to pulse-dominant legume intake where the constituent items were predominantly pulses but preparation was not specified. Results: After screening 1244 records, 15 studies met the inclusion criteria, comprising five case–control studies, five 4-week randomised controlled trials (RCTs), one 8-week randomised crossover trial, one controlled feeding study, two prospective cohort studies, and one other prospective study. Observational data from a single pooled case–control study suggest that higher pulse-dominant legume intake is compatible with modestly lower colorectal cancer risk, although the findings are mixed and often attenuate after adjustment for lifestyle and dietary confounders. Evidence for breast and oesophageal cancer and all-cancer mortality is limited, frequently subgroup-specific or highly sensitive to confounder control, and survivorship endpoints are represented mainly by short-term mechanistic and feasibility trials in colorectal cancer survivors rather than by long-term clinical outcomes. Notably, five of these navy bean interventions were conducted by a single research group using similar protocols, which constrains the independence of replication. Conclusions: Pulses can be considered practical components of cancer-protective dietary patterns, especially for colorectal cancer, but the heterogeneity of study designs, short-term interventions, limited sample sizes, and lack of preparation-specific exposure data preclude firm causal inferences; longer-term, rigorously designed trials and detailed observational work are needed to refine pulse-based recommendations for cancer risk reduction and to clarify any role in survivorship care. Full article
(This article belongs to the Special Issue The Nutritional Value of Legumes and Implications for Human Health)
29 pages, 5214 KB  
Systematic Review
Prevalence and Clinical Features of Polyendocrine Metabolic Ovarian Syndrome in the Gulf Cooperation Council Countries: A Systematic Review and Meta-Analysis
by Lama Ali Buhran, Meshal Bader Almutairi, Shehata Farag Shehata, Syed Esam Mahmood, Awad Alsamghan and Ramy Mohamed Ghazy
Healthcare 2026, 14(13), 1826; https://doi.org/10.3390/healthcare14131826 (registering DOI) - 23 Jun 2026
Abstract
Background: Polyendocrine metabolic ovarian syndrome (PMOS/PCOS) is the most common hormonal disorder in women of reproductive age and is linked to infertility as well as long-term metabolic and psychological problems. In the Gulf Cooperation Council (GCC) region, rising obesity, dietary changes, and sedentary [...] Read more.
Background: Polyendocrine metabolic ovarian syndrome (PMOS/PCOS) is the most common hormonal disorder in women of reproductive age and is linked to infertility as well as long-term metabolic and psychological problems. In the Gulf Cooperation Council (GCC) region, rising obesity, dietary changes, and sedentary lifestyles may be increasing its burden. However, prevalence estimates remain highly inconsistent due to differences in diagnostic criteria and measurement methods rather than true variation in disease rates. Objective: This study aimed to describe the situation by systematically pooling available evidence on the prevalence of PMOS among women in GCC countries and by summarizing the range of clinical features reported across included studies. Methods: We conducted a systematic review and meta-analysis following PRISMA 2020 guidelines. We searched five major bibliographic databases (PubMed, Scopus, Web of Science, Cochrane Library, and Embase) and the Google Scholar search engine for observational studies published up to 1 June 2026. Studies were eligible if they reported PMOS prevalence and related clinical features among women of reproductive age residing in GCC countries. After removing duplicates and screening 570 initially identified records, 25 studies met our inclusion criteria; 24 were included in the quantitative meta-analysis after excluding one high-risk study. Risk of bias was appraised using the Joanna Briggs Institute Checklist for Prevalence Studies. A random-effects meta-analysis using the DerSimonian-Laird method, combined with the Freeman-Tukey double arcsine transformation, was used to estimate the pooled prevalence. Heterogeneity was quantified using the I2 statistic and Cochran’s Q test. Subgroup analyses explored differences by country, diagnostic method, study setting, and publication period. Meta-regression was used to identify study-level factors that explained between-study variability. Results: Across 24 studies involving 77,890 women, the pooled prevalence of PMOS was 17.59% (95% CI: 12.98–23.40%). Country-level estimates ranged from 6.56% in Oman to 23.0% in Saudi Arabia. Heterogeneity across all analyses was extremely high (I2 = 99.6%), and meta-regression identified the diagnostic tool as the single most important source of variation, explaining 42.7% of between-study variance. Studies using structured clinical criteria (Rotterdam or NIH) yielded prevalence estimates around 13–14%, while those relying on self-report or physician diagnosis without standardized criteria reported considerably higher figures (20–37%). Common clinical features included menstrual irregularity (up to 100% of PMOS cases in clinical cohorts), hirsutism (5–100%), acne and oily skin (17–74%), and obesity (17–73%). Awareness of PMOS among women in the region was highly variable, ranging from under 3% to nearly 100%. Conclusions: PMOS is a significant public health concern across the GCC region. The markedly higher pooled prevalence combined with high rates of obesity and metabolic risk in this population calls for urgent, coordinated action. Standardizing diagnostic practices, investing in population-level screening, and developing culturally tailored awareness programs are essential steps toward reducing the clinical and social burden of PMOS. Full article
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22 pages, 5510 KB  
Article
A Cross-Sectional Study of Nutrition Knowledge, Diet Quality, Lifestyle, and Health Profiles Among Older Adults Attending Universities of the Third Age in Poland
by Anna Miller, Agata Kotowska and Sabina Lachowicz-Wiśniewska
Nutrients 2026, 18(12), 2025; https://doi.org/10.3390/nu18122025 (registering DOI) - 22 Jun 2026
Viewed by 180
Abstract
Background: Population ageing increases the burden of chronic diseases, multimorbidity, and functional limitations, making nutrition and lifestyle important modifiable determinants of healthy ageing. Universities of the Third Age (U3A) provide an educational and social environment for older adults, but multidimensional relationships between nutrition [...] Read more.
Background: Population ageing increases the burden of chronic diseases, multimorbidity, and functional limitations, making nutrition and lifestyle important modifiable determinants of healthy ageing. Universities of the Third Age (U3A) provide an educational and social environment for older adults, but multidimensional relationships between nutrition knowledge, diet quality, lifestyle, and health status in this population remain insufficiently characterized. This study aimed to assess these associations among older adults attending U3A in Poland. Methodology: A cross-sectional online survey was conducted between January and April 2026 among community-dwelling older adults participating in U3A programs. Of 700 distributed invitations and 520 returned questionnaires, 450 complete and eligible responses were included. The questionnaire was based on the KomPAN® framework and expanded with items on health, lifestyle, psychosocial resources, barriers to healthy eating, and sources of health information. Diet quality was assessed using the pro-Healthy Diet Index, non-Healthy Diet Index, and overall Diet Quality Index (DQI). Nutrition knowledge was measured using a 24-item scale. Analyses included distributional diagnostics, non-parametric group comparisons, FDR-corrected Spearman correlations, psychometric assessment, principal component analysis, multivariable regression with model diagnostics, and profile segmentation. Results: The mean age was 73.63 ± 5.73 years, and most participants were women. The median DQI was 15.59 [3.93–24.86], with a predominance of neutral diet quality. Nutrition knowledge was moderate, with a median score of 12.00 [9.00–15.00], and the scale showed very good internal consistency. PCA identified three dietary patterns: convenience/ultra-processed, prudent/health-promoting, and traditional meat-and-fat. Higher DQI was associated with better nutrition knowledge, greater physical activity, a more favorable sleep profile, regular meal timing, and lower disease burden. Participants with multimorbidity had significantly lower DQI. Segmentation distinguished a health-engaged/higher-resource profile and a lower-resource/nutritionally vulnerable profile. Conclusions: U3A participants in Poland are educationally and socially active but nutritionally heterogeneous. The predominance of neutral diet quality, moderate nutrition knowledge, and identifiable knowledge gaps indicates the need for targeted, practical, and behavior-oriented nutrition education supporting healthy ageing. Full article
(This article belongs to the Section Nutrition and Diabetes)
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17 pages, 1028 KB  
Article
Diet Quality, Healthy Practices, and Psychosocial Functioning Across School Youth, Students, and Adults in Poland: A Cross-Sectional Online Survey
by Klaudia Sochacka, Agata Kotowska and Sabina Lachowicz-Wiśniewska
Nutrients 2026, 18(12), 2022; https://doi.org/10.3390/nu18122022 (registering DOI) - 21 Jun 2026
Viewed by 188
Abstract
Background: This study aimed to compare a limited set of predefined diet-, lifestyle-, knowledge-, and psychosocial indicators across school youth, students, and adults in Poland, and to examine their associations with three predefined outcomes: BMI ≥ 25 kg/m2, poorer mental well-being, [...] Read more.
Background: This study aimed to compare a limited set of predefined diet-, lifestyle-, knowledge-, and psychosocial indicators across school youth, students, and adults in Poland, and to examine their associations with three predefined outcomes: BMI ≥ 25 kg/m2, poorer mental well-being, and high stress/overload. Diet quality, daily health-related practices, psychosocial well-being, and stress/overload may co-occur across different life stages, but online survey data require a focused analytical framework to avoid overinterpretation. Methods: This cross-sectional anonymous online survey included 360 respondents: 154 school youth aged 15–19 years, 127 students aged 20–29 years, and 79 adults aged 30 years or older. Dietary assessment was based on the KomPAN questionnaire and included the pro-healthy diet index, non-healthy diet index, and Diet Quality Index. Study-specific scores were used for knowledge, healthy practices, psychosocial well-being, and stress/overload. Analyses were restricted to predefined group comparisons, selected correlations, and three whole-sample adjusted logistic regression models. Results: Adults had the highest BMI and waist/hip circumference, whereas school youth showed the highest non-healthy diet index and more frequent high processed-food intake. Among the knowledge and psychosocial indicators, only obesity knowledge differed significantly between groups, with the highest mean value among students. Stress/overload was inversely associated with psychosocial well-being, and DQI was positively associated with psychosocial well-being after adjustment for age, sex, and group. In adjusted whole-sample models, BMI ≥ 25 kg/m2 was positively associated with age and DQI and inversely associated with physical activity frequency and regular meals; the positive DQI–BMI association was interpreted cautiously as potentially reflecting reverse causality, reporting bias, or compensatory dietary modification among respondents with excess body weight. Poorer mental well-being was associated with higher stress/overload and inversely associated with DQI, physical activity frequency, and family meals. High stress/overload was positively associated with highly processed food intake and inversely associated with regular meals. Conclusions: The findings suggest that diet quality, behavioral regularity, and psychosocial burden may be more informative than knowledge alone when describing health-related profiles across age-defined groups. Because the study was cross-sectional, self-reported, anonymous, and based on a modest sample, the results should be interpreted as preliminary and hypothesis-generating rather than causal. Full article
(This article belongs to the Special Issue Nutritional Psychiatry: Eating Behaviors and Mental Health Outcomes)
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42 pages, 603 KB  
Review
A Healthy Lifestyle Can Slow Immune System Aging and Reduce Age-Related Chronic Inflammation: A Narrative Review
by Marta Cąkała-Jakimowicz, Anna Domaszewska-Szostek and Monika Puzianowska-Kuźnicka
Int. J. Mol. Sci. 2026, 27(12), 5605; https://doi.org/10.3390/ijms27125605 (registering DOI) - 21 Jun 2026
Viewed by 397
Abstract
Age-related decline in immune system function is characterized by reduced numbers of naïve lymphocytes, the accumulation of senescent cells, impaired function of all immune cell types, and chronic low-grade inflammation (inflammaging). These alterations contribute to increased susceptibility to infections and malignancies, as well [...] Read more.
Age-related decline in immune system function is characterized by reduced numbers of naïve lymphocytes, the accumulation of senescent cells, impaired function of all immune cell types, and chronic low-grade inflammation (inflammaging). These alterations contribute to increased susceptibility to infections and malignancies, as well as to autoimmunity and other age-associated diseases. This article reviews current evidence on lifestyle interventions that may mitigate immune aging. Lifestyle-related strategies, including regular physical activity, nutritional interventions (e.g., different diets, caloric restriction, and other fasting-related approaches), stress reduction, and vaccination, are discussed as key modulators of immune function and systemic inflammation. Notably, vitamin D supplementation has been shown to reduce the incidence of autoimmune diseases by 22%. In comparison, caloric restriction has led to a decrease in CRP and TNF-α by 40% and 50%, respectively. Emerging complementary approaches, such as mind–body practices and controlled cold exposure, show promise, though current evidence remains limited and inconsistent. Therefore, integrated lifestyle strategies may slow aging-related immune decline and support healthy aging. However, longitudinal trials are required to define the optimal intervention parameters, population-specific thresholds, and the long-term durability of immune rejuvenation. Full article
(This article belongs to the Special Issue Understanding Aging in Health and Disease)
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20 pages, 7697 KB  
Article
Evaluating Post-Earthquake Reconstruction Through Just Recovery: Planning, Participation, and Spatial Justice in Hatay
by Berfin Karabakan Gökhan and Yelda Mert
Land 2026, 15(6), 1083; https://doi.org/10.3390/land15061083 - 18 Jun 2026
Viewed by 208
Abstract
Hatay experienced severe spatial, economic, and social losses following the earthquakes on 6 and 20 February 2023. Beyond the scale of physical destruction, the post-disaster period has brought deep transformations in everyday life, access to services, and the governance of space. This study [...] Read more.
Hatay experienced severe spatial, economic, and social losses following the earthquakes on 6 and 20 February 2023. Beyond the scale of physical destruction, the post-disaster period has brought deep transformations in everyday life, access to services, and the governance of space. This study examines the reconstruction process in Hatay from a perspective of just recovery and evaluates how the discourses of justice highlighted in policy documents are reflected in planning practice. Furthermore, the study offers empirical contributions on how justice is produced through spatial planning tools such as reserve area decisions, rubble management, expropriations, and access to services. Within the scope of the research, post-disaster policy documents, municipal reports, and media content were examined using qualitative content analysis, and the findings were supported by field-based spatial observations. The analyses show that, although the discourse of participation is frequently emphasized, it remains limited in decision-making processes; and issues related to the needs of vulnerable groups and equal access to services are more weakly represented. Spatial examples highlight the gap between normative discourses and practice through reserve area decisions, debris dumping management, and environmental risks. Overall, the study reveals that the principles of just recovery have been only partially implemented in the reconstruction process in Hatay, and that, for long-term resilience, participation, spatial equality, and the recognition of diverse lifestyles need to be strengthened at the institutional level. Full article
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17 pages, 500 KB  
Article
Research on the Purchase Behavior of Owner–Pet Matching Outfits Based on the Extended Theory of Planned Behavior
by Sisi Chen, Diqing Qian and Zengrui Xiao
Behav. Sci. 2026, 16(6), 1021; https://doi.org/10.3390/bs16061021 - 18 Jun 2026
Viewed by 199
Abstract
With the rapid expansion of the pet economy, owner–pet matching outfits have grown increasingly popular among pet owners. Grounded in the extended theory of planned behavior, this study investigates the key determinants of pet owners’ purchase intentions and actual purchase behaviors toward owner–pet [...] Read more.
With the rapid expansion of the pet economy, owner–pet matching outfits have grown increasingly popular among pet owners. Grounded in the extended theory of planned behavior, this study investigates the key determinants of pet owners’ purchase intentions and actual purchase behaviors toward owner–pet matching outfits, and explores the moderating effect of aesthetic risk on the intention–behavior transition. Questionnaire survey data from 222 pet owners were collected for empirical analysis, and regression analysis was adopted to verify the proposed research hypotheses. The empirical results reveal that subjective norms exert a direct promotional effect on consumer purchase behavior and indirectly boost such behavior through the partial mediating role of purchase intention. By contrast, behavioral attitude is positively associated with purchase intention and further stimulates purchase behavior via a full mediating pathway of purchase intention. Perceived behavioral control displays a significant positive direct impact on purchase behavior yet yields no significant effect on purchase intention. Furthermore, purchase intention serves as a robust positive predictor of purchase behavior, whereas aesthetic risk significantly weakens the association between purchase intention and purchase behavior. Brands are suggested to foster consumers’ favorable behavioral attitudes by optimizing product design, enriching practical functions, and minimizing potential risks to pets in owner–pet matching outfits. Meanwhile, enterprises should actively shape supportive subjective norms to popularize the owner–pet matching outfit wearing lifestyle. Additionally, brands need to enhance consumption accessibility through diversified sales channels, reasonable pricing strategies and abundant product style options. This study pioneers the application of the extended theory of planned behavior to the emerging field of owner–pet matching outfits, empirically verifying the positive effects of behavioral attitude, subjective norms, and perceived behavioral control on consumers’ purchase intention and purchase behavior. Full article
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24 pages, 2723 KB  
Article
Part 2: A Sector-Wide Survey of UK/British Isles Shelter Organisations Caring for Cats: Caregiver-Reported Approaches to Assessments, Behaviour Management and Homing Decisions
by Lauren R. Finka, Ana M. Barcelos, James Waterman, Avni Bhatia, Jenni L. McDonald, Rae Foreman-Worsley and Beth Skillings
Vet. Sci. 2026, 13(6), 590; https://doi.org/10.3390/vetsci13060590 - 18 Jun 2026
Viewed by 239
Abstract
Shelter organisations take responsibility for the care, assessment and homing of large numbers of domestic cats from diverse backgrounds. However, not all cats that come under shelter care are suited to close human-cohabitation or to certain types of human-domestic lifestyles. Shelter stakeholders may [...] Read more.
Shelter organisations take responsibility for the care, assessment and homing of large numbers of domestic cats from diverse backgrounds. However, not all cats that come under shelter care are suited to close human-cohabitation or to certain types of human-domestic lifestyles. Shelter stakeholders may undertake decision-making processes to determine how each cat should be managed and where they should go next. These processes may lead to different cat welfare experiences and long-term outcomes depending on how they occur, yet little is known about current approaches. The aim of this study was to characterise current approaches to cat and adopter assessments, behaviour management and homing decisions across the British Isles shelter sector, considering reported practices against sector minimum standards where applicable. A total of 393 quantitative and qualitative responses from employees and volunteers were received. Responses indicated that overall, stakeholders were consistently undertaking cat and prospective adopter assessments, with subsequent information used to support cat management, decision-making and homing. However, the degree of standardisation and objectivity associated with these processes was unclear, with considerable variation in approaches, including certain practices potentially associated with poor cat welfare outcomes identified. Examples include exposure to stressful handling and behavioural interventions and assessment ‘tests’, prolonged stays for harder-to-home cats and potentially suboptimal homing decisions for cats not suited to domestic ‘pet’ lifestyles. Identified opportunities to support welfare-friendly processes at the individual level include more consistent use of cats’ within-shelter behavioural presentations as grounds for ‘pet’-suitability assessments, and careful and consistent application of cat-labelling and terminology. It is also recommended that care is taken to ensure methods of cat assessments, behavioural interventions and homing decisions are pragmatic and optimised to positive cat welfare outcomes. Full article
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22 pages, 2313 KB  
Review
Contemporary Approaches Towards the Optimization of Embryo Implantation
by Christian Unogu, Monika Grymowicz, Anna Szeliga, Roman Smolarczyk, Anna Kostrzak, Ewa Rudnicka, Anna Duszewska, Gregory Bala, Martyna Grymowicz, Blazej Meczekalski and Eli Y. Adashi
J. Clin. Med. 2026, 15(12), 4723; https://doi.org/10.3390/jcm15124723 - 17 Jun 2026
Viewed by 263
Abstract
Background/Objectives: Embryo implantation is a highly regulated, multistep process requiring precise synchronization between a developmentally competent blastocyst and a receptive endometrium. Despite advances in reproductive medicine, implantation failure remains a major limiting factor in assisted reproductive technology (ART), particularly in cases of recurrent [...] Read more.
Background/Objectives: Embryo implantation is a highly regulated, multistep process requiring precise synchronization between a developmentally competent blastocyst and a receptive endometrium. Despite advances in reproductive medicine, implantation failure remains a major limiting factor in assisted reproductive technology (ART), particularly in cases of recurrent implantation failure (RIF). This review aims to summarize current knowledge on the molecular, cellular, and immunological mechanisms governing embryo–endometrial interaction and to evaluate contemporary strategies for optimizing implantation outcomes. Methods: This narrative review synthesizes the current literature on embryo implantation, including studies addressing uterine receptivity, etiological factors contributing to implantation failure, and emerging diagnostic and therapeutic approaches. The review integrates findings from molecular biology, clinical ART practices, and bioengineering-based models. Key areas include transcriptomic tools such as endometrial receptivity analysis, time-lapse imaging, artificial-intelligence-based embryo selection, and advanced in vitro models (e.g., microfluidic “womb-on-a-chip” systems and three-dimensional embryo–endometrial platforms). The literature was identified through major biomedical databases, following a structured but non-systematic approach. Results: Implantation success is dependent on a complex interplay of hormonal regulation, gene expression, immune modulation, and embryo quality. Disruption of uterine receptivity during the window of implantation is a critical contributor to infertility and RIF. Multiple factors—including genetic abnormalities, maternal age, lifestyle influences, immunological imbalance, uterine pathology, and chronic endometrial conditions—are implicated in implantation failure. Emerging technologies, such as AI-assisted embryo selection, transcriptomic profiling, and advanced in vitro implantation models, provide enhanced insight into implantation dynamics and offer potential for improved clinical outcomes. Conclusions: Advances in understanding embryo implantation and the development of innovative diagnostic and therapeutic technologies hold significant promise for improving reproductive success. However, further research, validation, and standardization are required before these approaches can be fully integrated into routine clinical practice. A more personalized and mechanism-based approach to implantation may ultimately enhance ART outcomes and reduce the burden of infertility. Full article
(This article belongs to the Special Issue Recent Developments in Gynecological Endocrinology: 2nd Edition)
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15 pages, 559 KB  
Article
Relationship Between Standing Long Jump Performance and Health-Related Indicators and Lifestyle Factors in Chilean Adolescents: A Cross-Sectional Study
by Felipe Montalva-Valenzuela, Eduardo Guzmán-Muñoz, Antonio Castillo-Paredes, Camila Tapia Gatica, Natalia Escobar Ruiz, Yeny Concha-Cisternas, Pablo Valdés-Badilla, Álvaro Farfán-Díaz and Exal Garcia-Carrillo
Healthcare 2026, 14(12), 1744; https://doi.org/10.3390/healthcare14121744 - 17 Jun 2026
Viewed by 191
Abstract
Background: The standing long jump (SLJ) is a field-based test of lower-limb muscular fitness in youth and a proposed indicator of health-related physical fitness. However, evidence on its relationship with psychological, sleep, dietary, and lifestyle factors in adolescents remains limited, particularly in Latin [...] Read more.
Background: The standing long jump (SLJ) is a field-based test of lower-limb muscular fitness in youth and a proposed indicator of health-related physical fitness. However, evidence on its relationship with psychological, sleep, dietary, and lifestyle factors in adolescents remains limited, particularly in Latin America. Objective: To examine the association between SLJ performance and health-related indicators and lifestyle factors in Chilean adolescents. Methods: A cross-sectional study was conducted with 145 adolescents (16.02 ± 1.09 years; 99 males, 46 females) from a subsidized secondary school in Chile. SLJ performance, handgrip strength, body mass index (BMI), physical activity (PAQ-A), sleep quality (PSQI), dietary indices (HCI and UHCI), and psychological symptoms (DASS-21) were assessed. Associations were examined using Pearson’s correlation and multiple linear regression, with false discovery rate (FDR) correction for multiple comparisons. Results: SLJ performance was positively associated with handgrip strength (r = 0.59, p < 0.001) and physical activity (r = 0.42, p < 0.001), and negatively associated with BMI (r = −0.30, p = 0.001) and anxiety (r = −0.24, p = 0.011). Sleep quality showed a weak inverse association that was not significant after FDR correction. Dietary indices were not associated with SLJ performance. In the adjusted model, sex (β = 0.224, p = 0.013), BMI (β = −0.275, p < 0.001), handgrip strength (β = 0.435, p < 0.001), and physical activity (β = 0.229, p = 0.002) were independently associated with SLJ performance, explaining 57% of the variance (R2 = 0.57, adjusted R2 = 0.523). Conclusions: SLJ performance is mainly associated with muscular strength, physical activity, and BMI in Chilean adolescents, while psychological, dietary, and sleep variables are not independently associated after adjustment. These findings support SLJ as a practical indicator of muscular fitness, but not of overall health. Due to the cross-sectional design, causal inference is not possible. Full article
(This article belongs to the Special Issue Physical Fitness and Physical Activity as Markers of Health)
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16 pages, 269 KB  
Article
Dietary Habits and Lifestyle Factors Associated with Vascular Diseases: A Case–Control Study
by Fethi Sada Zekey, Serkan Sahin, Zafer Cengiz Er, Kübra Uyar Zekey and Vugar Ali Turksoy
Healthcare 2026, 14(12), 1739; https://doi.org/10.3390/healthcare14121739 - 16 Jun 2026
Viewed by 117
Abstract
Background/Objectives: Vascular diseases remain a leading cause of global mortality, yet the dietary and lifestyle factors that contribute to them are not fully understood in Central Anatolian populations. This study aimed to quantify the dietary and lifestyle predictors of vascular disease status in [...] Read more.
Background/Objectives: Vascular diseases remain a leading cause of global mortality, yet the dietary and lifestyle factors that contribute to them are not fully understood in Central Anatolian populations. This study aimed to quantify the dietary and lifestyle predictors of vascular disease status in a case–control cohort from a tertiary care setting in Yozgat province. Methods: A total of 1452 adults were enrolled from Yozgat Bozok University Research Hospital: Cardiovascular Surgery (CVS; cases, n = 720) and Primary Care (PC; controls, n = 732). All participants completed a 43-item questionnaire on diet, lifestyle, and sociodemographic characteristics. Binary logistic regression was used to identify independent predictors of case status, with age, sex, education, and income being included in the model. Results: Chronic comorbidities were present in 33.9% of the control group and 80.3% of the case group. Use of olive oil was most strongly associated with control status (odds ratio [OR] = 0.17; 95% confidence interval [CI]: 0.11–0.27), followed by use of butter (OR = 0.25). Paradoxically, fast food (OR = 0.24) and junk food (OR = 0.31) consumption were more frequent among controls. The use of sunflower oil (OR = 2.30), diabetes (OR = 5.22), and elevated serum ferritin (OR = 1.04 per 10 ng/mL) independently predicted a higher likelihood of being in the case group. The model explained 54.8% of the variance (Nagelkerke R2 = 0.548). Conclusions: The apparently higher prevalence of unhealthy dietary behaviours among controls is most plausibly attributed to post-diagnosis dietary modification among cases (an ‘illness effect’), underscoring the window for intervention before disease onset. As this case–control design precludes causal inference, these associations are hypothesis-generating. Promoting olive oil and reducing sunflower oil represent practical, culturally feasible dietary targets for cardiovascular risk counselling in Central Anatolia, pending prospective confirmation. Full article
(This article belongs to the Topic Ultra Processed Foods and Human Health, 2nd Volume)
18 pages, 1003 KB  
Article
Tempered Enthusiasm: Consumer Perceptions of Autonomous Delivery Services
by Leon Booth, John Nelson, Yuting Zhang, Charles Karl, Anna Anund and Simone Pettigrew
Sustainability 2026, 18(12), 6104; https://doi.org/10.3390/su18126104 - 13 Jun 2026
Viewed by 401
Abstract
The rapid growth of online shopping has increased demand for home deliveries, leading to sustainability issues and logistical challenges such as labour shortages and congestion. Autonomous delivery vehicles, including drones, street robots, autonomous vans, and mobile vending machines, are emerging as potential solutions. [...] Read more.
The rapid growth of online shopping has increased demand for home deliveries, leading to sustainability issues and logistical challenges such as labour shortages and congestion. Autonomous delivery vehicles, including drones, street robots, autonomous vans, and mobile vending machines, are emerging as potential solutions. Understanding consumers’ perceptions of these technologies is critical for sustainable implementation. This exploratory study aimed to examine consumer reactions to emerging autonomous delivery services, providing insights into how consumers may respond to autonomous delivery systems encompassing multiple vehicle modes and the resulting policy implications. Eight online focus groups (n = 55) were conducted with a diverse range of participants to examine community attitudes to autonomous delivery services. Participants were shown videos depicting various autonomous delivery methods to foster informed responses. Thematic analysis of the transcripts identified recurring themes relating to participants’ preferences, concerns, and expectations. While participants had some concerns, they were largely receptive to using autonomous delivery services. Positive reactions centred around: (i) convenience, (ii) cost reductions, and (iii) novelty. Identified concerns included: (i) job losses, (ii) practical limitations of the delivery devices, (iii) degradation of urban environments, and (iv) facilitation of unhealthy lifestyles. Overall, the results suggest autonomous delivery systems have the potential to be popular, and proactive government policies are thus likely to be needed to ensure they are implemented in a manner that aligns with community expectations and minimises any negative sustainability outcomes. Full article
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28 pages, 1516 KB  
Article
Main Outcomes of the HEBE Trial: Improving Cardiorespiratory Fitness and Body Composition Through a Tailored Feasible Lifestyle Program
by Daniela Lucini, Federica Rota, Giuseppe Marano, Gianluigi Oggionni, Ester Luconi, Simona Iodice, Francesca Bianchi, Chiara Mandò, Giuseppina Bernardelli, Mara Malacarne, Silvana Castaldi, Patrizia Boracchi, Valentina Bollati, Mario Clerici, Elia Mario Biganzoli and on behalf of the HEBE Consortium
Nutrients 2026, 18(12), 1918; https://doi.org/10.3390/nu18121918 - 12 Jun 2026
Viewed by 462
Abstract
Background/Objectives: Lifestyle Modification Programs (LMPs) based on exercise and nutrition aim to prevent/manage chronic diseases and foster well-being. However, moving LMPs from research to medical practice can be challenging, as programs must be both effective and feasible. The primary goal of this study [...] Read more.
Background/Objectives: Lifestyle Modification Programs (LMPs) based on exercise and nutrition aim to prevent/manage chronic diseases and foster well-being. However, moving LMPs from research to medical practice can be challenging, as programs must be both effective and feasible. The primary goal of this study was to assess cardiorespiratory fitness (CRF) changes according to an LMP, measured through VO2max, as a key indicator of health outcomes and intervention efficacy. Methods: In this single-arm intervention study, 100 subjects were enrolled; per-protocol analysis of main parameters was performed on 85 participants (15 were excluded due to medical/technical reasons). A feasible intervention program (of low resource intensity with only two physician/patient encounters) provided personalized exercise prescription, optimized nutritional habits based on the Mediterranean diet and Healthy Eating Plate principles, and supported behaviour change. We assessed CRF through VO2max, a key indicator of health outcomes and intervention efficacy. We also analyzed, using regression analysis, the relationship between VO2max (the gold-standard measure of CRF) and METSpeak, a simpler, feasible parameter of CRF derived from Exercise Stress Testing. Body composition (BC) and AHA diet score were also measured at baseline and post-6-month intervention. Statistical analyses included paired comparisons and multivariable regression to explore factors influencing CRF changes. Results: Analysis on the primary outcome, VO2max, was performed according to the intention-to-treat principle and per-protocol. This feasible protocol resulted in a significant increase in VO2max, improvements in fat-free mass, and a reduction in fat mass. Overall, 42.4% of participants achieved an improvement of ≥1 MET, a change previously associated with reduced mortality risk. Older participants tend to experience smaller improvements in VO2max. Conclusions: Although observing an improvement in CRF and BC following an LMP is not surprising, the strength of the study is to show the feasibility of implementing an effective, feasible LMP into clinical routine, supporting the integration of such programs into clinical practice. Full article
(This article belongs to the Special Issue Effects of Exercise and Diet on Health)
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19 pages, 783 KB  
Article
The Influence of Dietary and Physical Exercise Habits on Melanoma Risk: A Case–Control Study
by Francesca Crespí-Payeras, Rosa Moll-Amengual, Neus Calbet-Llopart, Judit Mateu, Míriam Potrony, Cristina Carrera, Pablo Iglesias, Gemma Tell-Martí, Teresa Torres Moral and Susana Puig
Nutrients 2026, 18(12), 1919; https://doi.org/10.3390/nu18121919 (registering DOI) - 12 Jun 2026
Viewed by 268
Abstract
Background/Objectives: Obesity, food and nutrient intake, and physical activity (PA) have been linked to the occurrence of various types of cancer. However, evidence regarding their relationship with melanoma is limited. We aimed to assess whether body mass index (BMI), diet quality, food cooking [...] Read more.
Background/Objectives: Obesity, food and nutrient intake, and physical activity (PA) have been linked to the occurrence of various types of cancer. However, evidence regarding their relationship with melanoma is limited. We aimed to assess whether body mass index (BMI), diet quality, food cooking methods, and PA influence the risk of developing melanoma. Methods: This case–control study compared the demographic characteristics, dietary habits, and PA of 130 melanoma patients from the Hospital Clínic de Barcelona with 166 control subjects of similar age and sex distribution. Data was collected by means of a questionnaire, administered between January 2016 and February 2020. The association between these factors and melanoma was assessed using odds ratios for binary variables with 95% confidence intervals. Results: BMI was not found to be associated with the diagnosis of melanoma. However, restricting foods and limiting sugary products did show a correlation with lower melanoma risk, while dairy product restriction was associated with an increased risk. Consumption of processed meats and unhealthy cooking methods were also associated with an increased risk of melanoma development. Lastly, an inverse association between PA practice and frequency and melanoma risk was observed in women, while vigorous-intensity PA showed an inverse association regardless of sex. Conclusions: This study identifies specific dietary patterns and PA behaviors that may play a role in melanoma risk, highlighting the potential for personalized lifestyle-based prevention strategies. Full article
(This article belongs to the Section Clinical Nutrition)
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17 pages, 614 KB  
Systematic Review
Are School-Based Programs Effective in Tackling Childhood Obesity in Europe? A Systematic Review
by Cíntia Carneiro Gomes, Christos Triantafyllou and Joao Breda
Nutrients 2026, 18(12), 1916; https://doi.org/10.3390/nu18121916 - 12 Jun 2026
Viewed by 253
Abstract
Background: Childhood obesity remains a major public health challenge worldwide, with increasing prevalence across Europe. Schools represent an important setting for promoting healthy lifestyles through physical activity and nutrition-related interventions. This systematic review aimed to evaluate the effectiveness of school-based interventions promoting physical [...] Read more.
Background: Childhood obesity remains a major public health challenge worldwide, with increasing prevalence across Europe. Schools represent an important setting for promoting healthy lifestyles through physical activity and nutrition-related interventions. This systematic review aimed to evaluate the effectiveness of school-based interventions promoting physical activity and healthy eating behaviours among children and adolescents aged 6–18 years in European countries. Methods: A systematic literature review was conducted using PubMed and Scopus. Studies were eligible if they were conducted in school settings, targeted children and adolescents aged 6–18 years, were implemented in European countries, had a minimum duration of nine months, and assessed anthropometric and/or behavioural outcomes related to obesity prevention. Methodological quality was assessed using the Effective Public Health Practice Project (EPHPP) Quality Assessment Tool. Results: Sixteen studies conducted across nine European countries met the inclusion criteria. Intervention duration ranged from nine months to five years, and most studies employed multicomponent approaches combining physical activity promotion, nutrition education, environmental modifications, and parental involvement. Seven studies were rated as strong quality, six as moderate quality, and three as weak quality. Among the fourteen studies assessing BMI or other anthropometric outcomes, eleven (78.6%) reported statistically significant improvements in at least one obesity-related measure, including BMI, BMI z-score, waist circumference, waist-to-height ratio, body fat percentage, or overweight/obesity prevalence. Evidence regarding physical activity and nutrition-related outcomes was more heterogeneous, although several studies reported improvements in dietary behaviours, nutrition knowledge, sedentary behaviour, and physical activity levels. Positive anthropometric effects were more commonly observed in interventions lasting at least one academic year and in multicomponent programmes. Some studies also reported differential effects according to sex and parental educational background. Conclusions: The findings of this review suggest that long-term, multicomponent school-based interventions can contribute to improving obesity-related anthropometric outcomes among children and adolescents in European countries. However, evidence regarding sustained changes in physical activity and dietary behaviours remains less consistent. Future research should focus on identifying the most effective intervention components and strategies for achieving long-term behavioural change across diverse populations and educational contexts. Full article
(This article belongs to the Special Issue Nutritional Strategies in Pediatric Obesity and Metabolic Health)
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