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2 Results Found

  • Review
  • Open Access
31 Citations
6,498 Views
24 Pages

Glycogen Synthase Kinase 3: Ion Channels, Plasticity, and Diseases

  • Mate Marosi,
  • Parsa Arman,
  • Giuseppe Aceto,
  • Marcello D’Ascenzo and
  • Fernanda Laezza

Glycogen synthase kinase 3β (GSK3) is a multifaceted serine/threonine (S/T) kinase expressed in all eukaryotic cells. GSK3β is highly enriched in neurons in the central nervous system where it acts as a central hub for intracellular signali...

  • Article
  • Open Access
1,275 Views
23 Pages

FGF14 Peptide Derivative Differentially Regulates Nav1.2 and Nav1.6 Function

  • Parsa Arman,
  • Zahra Haghighijoo,
  • Carmen A. Lupascu,
  • Aditya K. Singh,
  • Nana A. Goode,
  • Timothy J. Baumgartner,
  • Jully Singh,
  • Yu Xue,
  • Pingyuan Wang and
  • Haiying Chen
  • + 5 authors

25 August 2025

Voltage-gated Na+ channels (Nav) are the molecular determinants of action potential initiation and propagation. Among the nine voltage-gated Na+ channel isoforms (Nav1.1–Nav1.9), Nav1.2 and Nav1.6 are of particular interest because of their dev...