Search Results (1,793)

Growing global supply chain uncertainties significantly threaten China’s forage import security. The evolving characteristics of the global forage trade network directly impact the stability of China’s supply. This study constructs a directed, weighted trade network based on global forage products trade data (2000–2024). Using complex network analysis methods, it systematically analyzes the network’s topological structure and evolutionary patterns, with a focus on their impact on China’s import security. The study addresses the following questions: What evolutionary patterns does the global forage trade network exhibit in terms of its topological structure? How does the evolution of this network impact the import security of forage products in China, specifically regarding supply chain stability and risk resilience? The research findings indicate the following: (1) From 2000 to 2024, the total volume of global forage products trade increased by 48.17%, primarily driven by forage products excluding alfalfa meal and pellets, which accounted for an average of 82.04% of volume annually. Additionally, the number of participating countries grew by 21.95%. (2) The global forage products trade network follows a power–law distribution, characterized by increasing network density, a clustering coefficient that initially declines and then rises, and a shortening of the average path length. (3) The core structure of the global forage products trade network shows an evolutionary trend of diffusion from core nodes in North America, Oceania, and Asia to multiple core nodes, including those in North America, Oceania, Europe, Africa, and Asia. (4) China’s forage products trade network displays distinct phase characteristics; however, imports face significant risks from high supply chain dependency and exposure to international price fluctuations. Based on these conclusions, it is recommended that China actively expands trade relations with potential product-exporting countries in Africa, encouraging enterprises to “go global.” Additionally, China should establish a three-dimensional supply chain security system, comprising maritime, land, and storage components, to enhance risk resistance and import safety. Full article

Sarcotaces arcticus (Collett, 1874) is a relatively large, internal parasitic copepod that infects many marine fishes. Although its large size suggests it may have a negative effect on host reproduction by reducing space available in the abdominal cavity (i.e., volumetric effect), such quantitative aspects of host-parasite relationships for S. arcticus have never been documented. We compared the prevalence and the ratio of live to dead parasites among sizes and sexes of two species of rockfish hosts (Sebastes ciliatus, Tilesius, 1813, dark rockfish; and Sebastes variabilis, Pallas, 1814, dusky rockfish) and quantified the reduction of internal space available in infected hosts. Samples were collected in southeast Alaskan waters where the two host rockfish species coexist in sympatry. Both total prevalence and prevalence of live S. arcticus were significantly higher in S. variabilis compared to S. ciliatus, because of higher prevalence in female S. variabilis. The relationship between body cavity volume, volume available for reproduction, and total length was isometric for both host species combined. An average live S. arcticus with a volume of 8.1 milliliters occupied about 45% in smaller hosts and about 5% in larger hosts of the volume available for reproductive organs. The high prevalence and large size of this parasite could significantly reduce fecundity and fitness of rockfish hosts through reductions in internal volume available for reproduction. Full article

Seed dormancy and germination is regulated by internal hormones and exogenous environment cues. Ethylene is one of the hormones that break seed dormancy and induce seed germination. Our previous study showed that N-degron pathway gene, proteolysis6 (PRT6) was involved in dormancy release by ethylene, the defection of which exhibiting ethylene-insensitivity in Arabidopsis thaliana. In the present study, through screening an ethyl methyl sulfonate-mutagenized (EMS) population of prt6−1, we isolated a recessive mutant that acted as a suppressor of prt6 that rescued its insensitivity to ethylene as well as a phenotype of shorter silique length. Further bulk segregant analysis on F2 population identified a premature termination located in the third exon of LONGIFOLIA1 (LNG1), previously reported in the regulation of longitudinal cell elongation. Mutation of LNG1 in prt6−1 background by CRISPR-Cas9 confirmed that LNG1 was epistatic to PRT6 in seed responsiveness to ethylene. Our finding proposed the pleiotropic effect of LNG1 in seed dormancy breakage by ethylene via PRT6, providing novel functional component at the downstream of the coordinated PRT6 and ethylene signaling pathway. Full article

The VRTN (vertebrin) gene plays a crucial role in regulating thoracic vertebral number in mammals; however, its function in goats remains largely unexplored. This study aimed to investigate genetic variations in the VRTN gene in Hainan black goats (HNBGs) and evaluate their associations with growth and meat traits. Using whole-genome and Sanger sequencing, we identified four SNPs in the VRTN gene, including three missense mutations (p.Pro615Ser, p.Arg490Lys, p.Thr476Met) and one synonymous mutation (p.Asp688Asp). Tissue expression profiling revealed high VRTN mRNA expression in skeletal muscle and low expression in internal organs, suggesting a potential role in muscle development. Temporal expression analysis indicated dynamic regulation during growth, with higher expression levels observed in early developmental stages. Association analyses revealed significant correlations between specific SNPs and key traits, including body length, chest circumference, carcass weight, and meat quality parameters. Notably, the p.Pro615Ser mutation was associated with a 0.441-fold reduction in VRTN expression and showed strong associations with multiple traits, underscoring its functional importance. These findings demonstrate that VRTN polymorphisms influence growth and muscle development in HNBGs, providing valuable insights for marker-assisted selection in goat breeding. Full article

Hydrogen is a promising alternative fuel for internal combustion engines due to its high specific energy, fast flame speed, and carbon-free combustion. In dual-fuel operation, it offers a practical route to reducing greenhouse gas emissions while remaining compatible with existing engine hardware. This work evaluates how the hydrogen energy substitution ratio (HSR = 50, 70, and 90%) influences spray dynamics, combustion characteristics, and emissions in a heavy-duty compression ignition engine. Simulations are validated against experiments and use a URANS RNG k–ε framework with a hybrid combustion model: the Eddy Dissipation Concept (EDC) coupled with detailed kinetics (111 species, 768 reactions) for auto-ignition and diffusion burning of diesel, and a G-equation for propagation of a hydrogen-rich premixed flame. The results reveal clear spray–combustion linkages. At HSR 50, the higher Weber number induces stronger breakup, yielding a smaller Sauter mean diameter and higher number-averaged droplet velocity; at HSR 90, the spray is more stable and less atomized, with larger droplets and a shorter vapor penetration length. Increasing the HSR reduces unburned hydrocarbons (UHCs) by more than 50% from HSR 50 to HSR 90 while modestly altering combustion phasing (a later CA50 and a shorter burn duration due to faster hydrogen flame propagation). The validated model provides a practical tool for optimizing dual-fuel settings and HSR–EGR–SOI trade-offs to balance efficiency and emissions. Full article

Background and Objectives: The COVID-19 pandemic caused significant disruptions in healthcare services. Foreign body impactions (FBIs), with Eosinophilic Esophagitis (EoE) being one of the leading underlying causes in adults, are some of the most common emergencies and often require endoscopy. The study assesses the impact of COVID-19 on the incidence and outcomes of foreign body impactions (FBIs) requiring endoscopy at Canadian tertiary centres in a single city. Methods: Patients presenting to tertiary care hospital emergency departments in Calgary (March 2019–Feb 2022) for FBI were identified using the AACRS (Alberta Ambulatory Care Reporting System) database using International Classification of Disease (ICD-9 and ICD-10) codes (T178, T181) and provincial diagnostic codes (935.1, 530.4) for a foreign body in the esophagus (530.13 and K20.0). One-way ANOVA (SPSS^® 27.0) analyzed incidence and disease progression across Pre-COVID-19 and COVID-19 years. Results: 759 patients were included in the analysis (274 Pre-COVID-19 (PC: March 2019–Feb 2020), 234 COVID-19 Year 1 (CY1: March 2020–Feb 2021), and 251 COVID-19 Year 2 (CY2: March 2021–Feb 2022)). The mean age remained consistent, with two-thirds being male. Food was the predominant type of FBI (>90%). The incidence of new EoE in EDs declined from PC (60.9%) to CY1 (47.4%) (p < 0.001), while endoscopic resolution remained >96%. Follow-up endoscopies in outpatient settings remained stable (~60%). Non-EoE causes of FBI, including esophagitis and cancer, increased in CY2. The mean ED length of stay rose in CY2, but this was not statistically significant (p = 0.06). Conclusions: This study highlights the resilience of emergent endoscopic care in Calgary during COVID, despite a decline in new EoE diagnoses, which might be due to access barriers. Full article

Rootstock choice offers a powerful lever for tailoring economically important trees to adverse environments. Camellia oleifera Abel., a premier oil-producing species cultivated widely on red-soil hills, suffers large yield losses under chronic phosphorus deficiency. We grafted a single elite scion (CL4) onto three contrasting rootstocks (CL4, CL3, CL53) and monitored growth and root transcriptomes for 1.5 years under adequate (1 mM) or limiting (0 mM) P supply. Under low-P stress, the rootstock identity reshaped the root architecture: CL4/CL3 produced the longest, most extensive network, increasing the total root length by 49.7%, the surface area by 52.9%, and the volume by 42.6% relative to the control, whereas leaf morphology responded solely to P supply, not to the graft combination. CL4/CL3 also accumulated up to more than 17.5% of root biomass and 28.25% of whole-plant biomass than any other combination. Physiologically, CL4/CL3 acted as an aggressive P miner, accumulating 67.8% more P in its roots than the self-grafted control under P limitation, while CL4/CL4 maximized the internal P use efficiency, showing a 44.74% higher root P use efficiency than CL4/CL53—two contrasting yet effective strategies for coping with low-P stress. Transcriptome profiling uncovered 1733 DEGs in the CL4/CL3 and 2585 in the CL4/CL4 roots, with 150 and 255 uniquely co-expressed genes, respectively. CL4/CL3 up-regulated organic-acid and phenylpropanoid pathways; CL4/CL4 activated defense and phosphate transport networks. qRT-PCR of six genes confirmed that CL4/CL3 mounted a stronger low-P response via MAPK, hormonal, and lipid–metabolic signaling. These results provide a mechanistic framework for rootstock-mediated P efficiency and establish a foundation for the molecular breeding of C. oleifera under nutrient-limited conditions. Full article

Background: There is no consensus on the best treatment method for calcaneal fractures. The topic of lower limb biomechanics following calcaneal fracture treatment with various fixation methods has not been fully explored. The aim of the study was to assess the balance and load distribution of the lower limbs in patients after various methods of stabilization of calcaneal fractures. Methods: In this two-center study, we retrospectively collected data from 19 patients treated with internal plate fixation at a mean age of 46 years and 27 patients treated with Ilizarov external fixation at a mean age of 50 years. Using the Zebris Medical pedobarophragmatic platform, we assessed the percentage distribution of lower limb loads and balance. Results: There were no significant differences in total load distribution for both the operated (p = 0.489) and non-operated limb (p = 0.46), between the Ilizarov method group and the internal plate group. In the Ilizarov fixation group, total load distribution was 46.89% on the treated limb, and 53.11% on the uninjured limb, p = 0.077. In the internal plate fixation group, the mean total load distribution was 41.57% in the treated limb, and 57.89% in the uninjured limb, p = 0.008. The median CoG (center or gravity) sway path length was 132.41 cm and 170.21 cm in the Ilizarov and internal plate group, respectively, p = 0.023. The median CoG sway areas were 0.84 cm² and 7.57 cm² in the Ilizarov method group and internal plate fixation group, respectively, p < 0.001. Conclusions: The Ilizarov method was associated with more symmetrical load distribution and improved balance performance compared to internal plate fixation. Static biomechanical parameters of calcaneal fracture treatment were better in the Ilizarov group compared to patients with internal plate fixation. Full article

A solar-pumped Ce:Nd:YAG laser amplifier design is proposed to address the challenge of scaling output power in solar-pumped laser oscillators while maintaining high beam quality. The design employs a 1.33 m² flat Fresnel lens with a 2 m focal length as a primary concentrator, which is combined with a secondary homogenizing concentrator, featuring 40 mm × 40 mm input aperture, 200 mm length, and 11.3 mm × 26 mm output aperture, to provide efficient coupling and uniform distribution of solar radiation onto a 2.9 mm thick Ce:Nd:YAG slab with 11.3 mm × 26 mm surface area and two beveled corners. This geometry enables multiple total internal reflections of a 1064 nm TEM₀₀ mode seed laser beam inside the slab, ensuring efficient interaction with the active Ce³⁺ and Nd³⁺ ions in the gain medium. Performed numerical analysis shows that the present approach can deliver a uniform solar pump power density of 2.5 W/mm² to the slab amplifier. This value is 2.05-times higher than the numerically calculated power density incident on the Nd:YAG slab of the previous solar-pumped amplifier that achieved the highest continuous-wave laser gain of 1.64. Furthermore, the optimized slab geometry with 0.44 width-to-height ratio allows the seed laser to undergo 32 internal reflections, extending its optical path length by a factor of 1.45 compared to the earlier design. These numerical achievements, combined with the Ce:Nd:YAG medium’s capacity to deliver nearly 1.57-times more laser power than Nd:YAG, reveal the potential of proposed design to yield a gain enhancement factor of 4.16, making the first solar-pumped Ce:Nd:YAG amplifier a promising solution toward energy-efficient, sustainable solutions for terrestrial and space applications. Full article

Species of Trichoderma are currently in high demand as eco-friendly and commercial biocontrol agents due to the proliferation of organic farming methods. This study focused on the potential biocontrol agents of Trichoderma against plant-pathogenic fungi. Trichoderma strains were isolated from different sources (soil, grapevine tissues, lemon fruit, and maize seeds), and were characterized morphologically on two culture media, i.e., Potato Dextrose Agar and Malt Extract Agar, and molecularly using two gene regions: translation elongation factor 1 (TEF) and nuclear ribosomal internal transcribed spacer (ITS). Phylogenetic trees were constructed. As a result, two Trichoderma species were identified, i.e., T. afroharzianum and T. longibrachiatum. The biocontrol effects of all isolated strains of Trichoderma on Fusarium plant damping-off and the promotion of plant growth were evaluated. Additionally, the antagonistic efficiency of Trichoderma spp. against F. proliferatum using the dual-culture method was evaluated. Under greenhouse conditions, T. afroharzianum strains AEMCTa3 and AEMCTa6 were used to treat maize plants infected with Fusarium. The application of Trichoderma significantly reduced the disease index to 15.6% and 0%, respectively. Additionally, maize seedlings showed significant improvements in shoot and root lengths and fresh and dry weights and increased photosynthetic pigment contents compared to Fusarium-infected plants and the untreated control. The gas chromatography–mass spectrometry (GC-MS) analysis of T. afroharzianum extracts identified a variety of bioactive compounds. These compounds included antifungal substances like N-ethyl-1,3-dithioisoindoline, as well as plant growth-promoting hormones like 6-pentyl-α-pyrone and gibberellic acid. Interestingly, the analysis also revealed new phenylacetic acid derivatives that may play important roles in both plant health and disease resistance. From a practical perspective, developing diverse application methods for Trichoderma is essential to optimize its role as a biocontrol agent and a plant growth promoter, thereby supporting sustainable agriculture through improved adaptability and effectiveness across different farming systems. Full article

This work evaluates a hydrogen-fueled planar micro-combustor featuring three triply periodic minimal surface (TPMS) structures, namely, gyroid, lidinoid, and Neovius matrix lattices, aiming to advance heat transfer processes and enhance system efficiency in micro-thermophotovoltaic (MTPV) applications. Through three-dimensional numerical investigations, a series of simulations are conducted under varying TPMS lengths, inlet volume flow rate, and inlet equivalence ratios to optimize the design and operating conditions. The outcomes reveal that increasing the length of the TPMS structures is an effective means of improving heat transfer from the combustion zone to the walls, as indicated by significant increases in both mean wall temperature and radiation efficiency. However, longer internal structures reduce the uniformity of wall temperature and slightly increase entropy generation. Of the three topologies, the Neovius lattice demonstrates superior performance in all length scales, exhibiting a marginal improvement over the gyroid and a substantially greater advantage over the lidinoid structure. Increasing the inlet volume flow rate enhances wall temperature and its uniformity; however, the performance parameters decrease for all structures, indicating a limitation of the micro-combustor in benefiting from higher input power. Notably, the gyroid structure shows a lower rate of performance degradation at higher velocities, making it a potentially ideal design under such conditions. Finally, varying the equivalence ratio identifies the stoichiometric condition as optimal, yielding superior performance metrics compared to both lean and rich mixtures. Full article

Hydraulic fracturing is a critical technical means for enhancing production in gas fields, and post-fracturing flow-back constitutes a crucial phase of fracturing operations. Proppant backflow during the flow-back process significantly impacts both the effectiveness of stimulation and subsequent production. Particularly for tight gas reservoirs, achieving rapid post-fracturing flow-back while preventing proppant re-flux is essential. To date, domestic and international scholars have conducted extensive research on proppant backflow during flow-back operations, with laboratory experimental studies serving as a vital investigative approach. However, due to limitations in experimental apparatuses, further investigation is required regarding the migration mechanisms of proppants during flow-back, proppant backflow prevention techniques, and associated operational parameters. This paper developed a novel visualized flow chamber capable of simulating proppant migration in vertical fractures under closure stress conditions. Extensive proppant backflow experiments conducted using this device revealed that (1) proppant backflow initiates at weak structural zones near the two-phase interface boundaries; (2) proppant backflow occurs in three distinct stages, with varying fluid erosive capacities on proppant particles at each phase; (3) a multi-stage fiber injection sand control process was optimized; (4) at low proppant concentrations (<10 kg/m²), the fiber concentration should be 0.8%; at high proppant concentrations (>10 kg/m²), the fiber concentration should be 1.2%. The recommended fiber length is 6 mm. Full article

For more than 20 years, after the introduction of the first robotic system, research on prostate cancer (PCa) surgery has mainly focused on evaluating outcomes of Robotic-Assisted Radical Prostatectomy (RARP). In the last few years, however, a new generation of innovative techniques, surgical approaches, and expanded indications have emerged. The Single Port (SP) robotic system was the first real hardware innovation in robotic surgery, and has already demonstrated advantages in terms of shorter length of stay, better cosmetic results and reduced postoperative pain. Artificial Intelligence (AI)-powered algorithms are being proposed as reliable tools for surgical assistance, aiding in standardization and mass implementation of robotic training. New surgical indications are emerging on the basis of patient and tumor characteristics. The extensive adoption of PCa screening and the precision of diagnostic tools have increased the rate of PCa diagnoses in a localized stage. Partial prostatectomy, despite needing further validation, has emerged as a safe and minimally invasive treatment option for confined tumors, able to minimize the side effects of prostate surgery. For locally advanced PCa, radioguided surgery has not only enhanced the oncological effectiveness of lymphadenectomy by enabling the precise identification and extraction of pathological lymph nodes, but has also contributed to minimizing the side effects associated with unnecessarily extensive dissections. Finally, in light of the increased efficacy of modern systemic therapies and the longer life expectancy, RP is currently being evaluated for primary tumor management in the metastatic phase. Despite the novelty of the aforementioned treatment options, they are already set to shape the future evolution of PCa management and international guidelines. Full article

This paper examines the quotative system of Sri Lankan English. Quotatives are identified in face-to-face conversations in the Sri Lankan component of the International Corpus of English. The use of kiyala indicating and following quoted material has been transferred from Sinhala, one of the indigenous languages of the country, into Sri Lankan English. Together with the occurrence of complementising that, the localisation of the Sri Lankan English quotative system is evident. Special emphasis is given to the choice between BE like and SAY, the by far most frequent quotative forms in the informal spoken data analysed. They are annotated with established structural (e.g., content of the quote or tense) and sociobiographic variables (e.g., age and gender of the speaker) apparent from earlier quotative research, but also with new ones (e.g., quote length or speakers’ stays abroad or media exposure to particular varieties of English). Via a generalised linear mixed-effects model tree implementing the latest methodological suggestions for classification trees, it is found that BE like is favoured over SAY in Sri Lankan English with younger speakers—particularly when the conversation took place after 2015 and events are narrated using the historical present. Full article

Background/Objectives: The aim of the study was to investigate the risk factors related to early implant failures in patients treated in a private implant clinic. Methods: The study was retrospectively conducted on 392 patients (mean age = 51.2 ± 15.4 years, 48.9% female and 51.1% male) who received 930 dental implants within the period from 2000 to 2020. Included patients had received at least one implant. Patients were excluded in case of incomplete dental records that did not contain the necessary information, including personal information (patient’s name, age, gender, history and current condition of systemic diseases) and treatment protocol record. No patients were excluded on the basis of systemic disease if it did not contraindicate dental implant surgery. Patient-related variables (age, gender, smoking, history of periodontitis, accompanying disease), surgical-related variables (surgical technique, bone augmentation, lateral sinus lift, internal sinus lift, immediate implant placement after tooth extraction, immediate mucosal grafting, insertion torque,) and implant-related variables (implant design, implant level, implant surface, site of implant placement, implants diameter, length and implants brand name) were recorded. Results: GEE analysis results showed that the implant-based failure rate before or at the abutment connection stage was 5.8%. Seven factors were identified associated with early implant failures: male gender, smoking, history of radiotherapy and chemotherapy, maxilla implant placement, non-submerged healing method, implant design and implant brand. Conclusions: In light of the results obtained, both patient-related variables (gender, smoking, history of radiotherapy and chemotherapy) and variables related to the type of implant, its position and the surgical technique used (maxilla implant placement, non-submerged healing method, implant design and implant brands) were found to be statistically correlated with early failures in this study. Full article