Search Results (4,972)

Accurate diagnosis of sinusitis is essential due to its widespread prevalence and its considerable impact on patient quality of life. While multiple imaging techniques are available for detecting maxillary sinus, computed tomography (CT) remains the preferred modality because of its high sensitivity and spatial resolution. Although recent advances in deep learning have led to the development of automated methods for sinusitis classification, many existing models perform poorly in the presence of complex pathological features and offer limited interpretability, which hinders their integration into clinical workflows. In this study, we propose a hybrid deep learning framework that combines EfficientNetB0, a convolutional neural network, with the Swin Transformer, a vision transformer, to improve feature representation. An attention-based fusion module is used to integrate both local and global information, thereby enhancing diagnostic accuracy. To improve transparency and support clinical adoption, the model incorporates explainable artificial intelligence (XAI) techniques using Gradient-weighted Class Activation Mapping (Grad-CAM). This allows for visualization of the regions influencing the model’s predictions, helping radiologists assess the clinical relevance of the results. We evaluate the proposed method on a curated maxillary sinus CT dataset covering four diagnostic categories: Normal, Opacified, Polyposis, and Retention Cysts. The model achieves a classification accuracy of 95.83%, with precision, recall, and F1 score all at 95%. Grad-CAM visualizations indicate that the model consistently focuses on clinically significant regions of the sinus anatomy, supporting its potential utility as a reliable diagnostic aid in medical practice. Full article

The increasing adoption of electric vehicles (EVs) within intelligent transportation systems (ITSs) has elevated the importance of cybersecurity, especially with the rise in Vehicle-to-Everything (V2X) communications. Traditional intrusion detection systems (IDSs) struggle to address the evolving and complex nature of cyberattacks in such dynamic environments. To address these challenges, this study introduces a novel deep learning-based IDS designed specifically for EV communication networks. We present a hybrid model that integrates convolutional neural networks (CNNs), long short-term memory (LSTM) layers, and adaptive learning strategies. The model was trained and validated using the VeReMi dataset, which simulates a wide range of attack scenarios in V2X networks. Additionally, an ablation study was conducted to isolate the contribution of each of its modules. The model demonstrated strong performance with 98.73% accuracy, 97.88% precision, 98.91% sensitivity, and 98.55% specificity, as well as an F1-score of 98.39%, an MCC of 0.964, a false-positive rate of 1.45%, and a false-negative rate of 1.09%, with a detection latency of 28 ms and an AUC-ROC of 0.994. Specifically, this work fills a clear gap in the existing V2X intrusion detection literature—namely, the lack of scalable, adaptive, and low-latency IDS solutions for hardware-constrained EV platforms—by proposing a hybrid CNN–LSTM architecture coupled with an elastic weight consolidation (EWC)-based adaptive learning module that enables online updates without full retraining. The proposed model provides a real-time, adaptive, and high-precision IDS for EV networks, supporting safer and more resilient ITS infrastructures. Full article

In-cylinder pressure provides critical insights for analyzing and optimizing combustion in internal combustion engines, yet its acquisition across the full operating space requires extensive testing, while physics-based models are computationally demanding. Machine learning (ML) offers an alternative, but its application to direct reconstruction of full pressure traces remains limited. This study evaluates three strategies for reconstructing cylinder pressure under unmeasured operating conditions, establishing a machine learning-assisted framework that generates the complete pressure–crank angle (P–CA) trace. The framework treats crank angle and operating conditions as inputs and predicts either pressure directly or apparent heat release rate (HRR) as an intermediate variable, which is then integrated to reconstruct pressure. In all approaches, discrete pointwise predictions are combined to form the full P–CA curve. Direct pressure prediction achieves high accuracy for overall traces but underestimates HRR-related combustion features. Training on HRR improves combustion representation but introduces baseline shifts in reconstructed pressure. A hybrid approach, combining non-combustion pressure prediction with combustion-phase HRR-based reconstruction delivers the most robust and physically consistent results. These findings demonstrate that ML can efficiently reconstruct in-cylinder pressure at unmeasured conditions, reducing experimental requirements while supporting combustion diagnostics, calibration, and digital twin applications. Full article

Induction motors (IMs) are crucial in many industrial applications, offering a cost-effective and reliable source of power transmission and generation. However, their continuous operation imposes considerable stress on electrical and mechanical parts, leading to progressive wear that can cause unexpected system shutdowns. Bearings, which enable shaft motion and reduce friction under varying loads, are the most failure-prone components, with bearing ball defects representing most severe mechanical failures. Early and accurate fault diagnosis is therefore essential to prevent damage and ensure operational continuity. Recent advances in the Internet of Things (IoT) and machine learning (ML) have enabled timely and effective predictive maintenance strategies. Among various diagnostic parameters, vibration analysis has proven particularly effective for detecting bearing faults. This study proposes a hybrid diagnostic framework for induction motor bearings, combining vibration signal analysis with Support Vector Machines (SVMs) and Artificial Neural Networks (ANNs) in an IoT-enabled Industry 4.0 architecture. Statistical and frequency-domain features were extracted, reduced using Principal Component Analysis (PCA), and classified with SVMs and ANNs, achieving over 95% accuracy. The novelty of this work lies in the hybrid integration of interpretable and non-linear ML models within an IoT-based edge–cloud framework. Its main contribution is a scalable and accurate real-time predictive maintenance solution, ensuring high diagnostic reliability and seamless integration in Industry 4.0 environments. Full article

This research is based on the acoustic package design of new energy vehicles, investigating the application of the hybrid Finite Element–Statistical Energy Analysis (FE-SEA) model in predicting the high-frequency dynamic response of automotive structures, with a focus on the modeling and correction methods for hybrid point connections. New energy vehicles face unique acoustic challenges due to the special nature of their power systems and operating conditions, such as high-frequency noise from electric motors and electronic devices, wind noise, and road noise at low speeds, which directly affect the vehicle’s ride comfort. Therefore, optimizing the acoustic package design of new energy vehicles to reduce in-cabin noise and improve acoustic quality is an important issue in automotive engineering. In this context, this study proposes an improved point connection correction factor by optimizing the division range of the decision circle. The factor corrects the dynamic stiffness of point connections based on wave characteristics, aiming to improve the analysis accuracy of the hybrid FE-SEA model and enhance its ability to model boundary effects. Simulation results show that the proposed method can effectively improve the model’s analysis accuracy, reduce the degrees of freedom in analysis, and increase efficiency, providing important theoretical support and reference for the acoustic package design and NVH performance optimization of new energy vehicles. Full article

This research introduces a hybrid framework that integrates stochastic modeling and machine learning for predicting postprandial glucose levels in individuals with Type 1 Diabetes (T1D). The primary aim is to enhance the accuracy of glucose predictions by merging a biophysical Glucose–Insulin–Meal (GIM) model with advanced machine learning techniques. This framework is tailored to utilize the Kaggle BRIST1D dataset, which comprises real-world data from continuous glucose monitoring (CGM), insulin administration, and meal intake records. The methodology employs the GIM model as a physiological prior to generate simulated glucose and insulin trajectories, which are then utilized as input features for the machine learning (ML) component. For this component, the study leverages the Light Gradient Boosting Machine (LightGBM) due to its efficiency and strong performance with tabular data, while Long Short-Term Memory (LSTM) networks are applied to capture temporal dependencies. Additionally, Bayesian regression is integrated to assess prediction uncertainty. A key advancement of this research is the transition from a deterministic GIM formulation to a stochastic differential equation (SDE) framework, which allows the model to represent the probabilistic range of physiological responses and improves uncertainty management when working with real-world data. The findings reveal that this hybrid methodology enhances both the precision and applicability of glucose predictions by integrating the physiological insights of Glucose Interaction Models (GIM) with the flexibility of data-driven machine learning techniques to accommodate real-world variability. This innovative framework facilitates the creation of robust, transparent, and personalized decision-support systems aimed at improving diabetes management. Full article

The hybrid Sechium edule H387 07, commonly known as chayote, has shown potential as an antiproliferative, cytotoxic, and pro-apoptotic agent in the murine leukemia cell lines P388 (macrophagic) and J774 (monocytic) and in the myelomonocytic leukemia cell line WEHI-3. However, despite these reported bioactivities, its pharmacokinetic profile remains largely unexplored. Understanding the absorption, distribution, and elimination of this hybrid is critical for addressing unmet therapeutic needs and for advancing the development of natural product-based therapies. These effects are attributed to the presence of phenols, flavonoids, and cucurbitacins in its organic extracts. In this study, the pharmacokinetic parameters of secondary metabolites from methanolic extracts of Sechium H387 07 were evaluated after oral administration in mice, while its segregant H387 M16 was subjected to complementary phytochemical characterization. Methanolic extracts of Sechium edule H387 07 were orally administered to mice at doses of 8, 125, and 250 mg/kg, and plasma, liver, and urine samples were collected at 1, 6, 24, and 48 h post-treatment. High-performance liquid chromatography (HPLC) identified polyphenols and cucurbitacins, notably cucurbitacin B (CuB) and cucurbitacin IIA (CuIIA), in the biological samples, and pharmacokinetic variables such as the maximum plasma concentration (C_max), time to reach maximum concentration (T_max), half-life (T_1/2), and volume of distribution (V_d) were determined. For instance, CuB exhibited a C_max of 37.56 µg/mL at 1 h post-dose after oral administration of 125 mg/kg, confirming its rapid absorption and systemic distribution. Notably, the presence of CuIIA in plasma was documented for the first time, along with the pharmacokinetic profiles of apigenin, phloretin, CuB, CuE, and CuI. In parallel, the segregant H387 M16 was characterized via colorimetric assays, thin-layer chromatography (TLC), HPLC, and antioxidant activity tests, which revealed high levels of flavonoids, phenols, and cucurbitacins, with an antioxidant activity of approximately 75% at the highest tested dose (1 mg/mL), supporting its suitability for future bioassays. Overall, these findings not only provide novel pharmacokinetic data for key metabolites of the H387 07 hybrid but also establish the phytochemical and antioxidant profile of its segregant H387 M16. This dual characterization strengthens the evidence of the therapeutic potential of Sechium genotypes and provides a valuable foundation for future studies aiming to develop standardized protocols and explore translational applications in drug development and natural product-based therapies. Full article

Circulating tumor cells (CTCs) are crucial biomarkers for lung cancer metastasis and recurrence, garnering significant clinical attention. Despite this, efficient and cost-effective detection methods remain scarce. Consequently, there is an urgent demand for the development of highly sensitive CTC detection technologies to enhance lung cancer diagnosis and treatment. This study utilized microspheres and A549 cells to model CTCs, assessing the impact of acoustic field forces on cell viability and proliferation and confirming capture efficiency. Subsequently, CTCs from the peripheral blood of patients with lung cancer were captured and identified using fluorescence in situ hybridization, and the results were compared to the immunomagnetic bead method to evaluate the differences between the techniques. Finally, epidermal growth factor receptor (EGFR) mutation analysis was conducted on CTC-positive samples. The findings showed that acoustic microfluidic technology effectively captures microspheres, A549 cells, and CTCs without compromising cell viability or proliferation. Moreover, EGFR mutation analysis successfully identified mutation types in four samples, establishing a basis for personalized targeted therapy. In conclusion, acoustic microfluidic technology preserves cell viability while efficiently capturing CTCs. When integrated with EGFR mutation analysis, it provides robust support for the precise diagnosis and treatment of lung cancer as well as personalized drug therapy. Full article

Accurate prediction of soil–structure interface shear strength (τ_max) is critical for reliable geotechnical design. This study combines experimental testing with interpretable machine learning to overcome the limitations of traditional empirical models and black-box approaches. Ninety large-displacement ring shear tests were performed on five sands and three interface materials (steel, PVC, and stone) under normal stresses of 25–100 kPa. The results showed that particle morphology, quantified by the regularity index (RI), and surface roughness (R_t) are dominant factors. Irregular grains and rougher interfaces mobilised higher τ_max through enhanced interlocking, while smoother particles reduced this benefit. Harder surfaces resisted asperity crushing and maintained higher shear strength, whereas softer materials such as PVC showed localised deformation and lower resistance. These experimental findings formed the basis for a hybrid symbolic regression framework integrating Genetic Programming (GP) with Shapley Additive Explanations (SHAP), Fourier feature augmentation, and physics-informed constraints. Compared with multiple linear regression and other hybrid GP variants, the Physics-Informed Neural Fourier GP (PIN-FGP) model achieved the best performance (R² = 0.9866, RMSE = 2.0 kPa). The outcome is a set of five interpretable and physics-consistent formulas linking measurable soil and interface properties to τ_max. The study provides both new experimental insights and transparent predictive tools, supporting safer and more defensible geotechnical design and analysis. Full article

Language learners increasingly rely on intelligent digital tools to supplement their learning experiences, yet existing chatbots often provide limited support, lacking adaptability, personalization, or domain-specific intelligence. This study introduces a novel AI-powered multi-agent chatbot architecture designed to support English–Arabic translation and language learning. Developed through a three-phase methodology, offline preparation, real-time deployment, and evaluation, the system employs both retrieval-based and generative AI models, with specialized agents managing tasks such as translation, example retrieval, user translation review, and learning feedback. The chatbot was developed using a hybrid architecture incorporating fine-tuned Generative Pre-trained Transformer (GPT) model, sentence embedding techniques, and similarity evaluation metrics. A user study involving 40 undergraduate students and 4 faculty members evaluated the system across usability, effectiveness, and pedagogical value. Results show that the multi-agent chatbot significantly enhanced learner engagement, provided accurate and contextually appropriate language support, and was positively received by both students and instructors. These findings demonstrate the value of multi-agent design in language learning applications and highlight the potential of AI-driven chatbots as intelligent educational assistants. Full article

In Hong Kong, the interaction between traditional values and modern influences creates a unique cultural landscape that influences family dynamics, intergenerational communication, and adolescent mental health. This study aimed to fill critical research gaps by exploring the relationship between authoritative and authoritarian parenting styles within this hybrid cultural context. Parenting style scores were based on the PSDQ-26 questionnaires completed by both parents of 2325 students. These students also provided demographic data used in the analysis (1013 girls, M_age = 13.35, SD = 1.22). The data analysis examined the correlations between parenting styles and variations across gender and age groups. Contrary to patterns observed in Western contexts, the results indicated no significant correlation between authoritative and authoritarian parenting styles (r = 0.02, p > 0.05), suggesting a complex coexistence influenced by Hong Kong’s hybrid sociocultural context. Notably, the study revealed gender-based differences: boys’ parents reported higher levels of democratic participation and reasoning, reflecting authoritative parenting, while also showing greater use of physical coercion and punitive discipline, indicative of authoritarian parenting. Authoritative parenting, but not authoritarian parenting, showed a decline as children matured. By investigating these dynamics, the study not only addresses a significant gap in the literature but also enhances the understanding of how cultural and developmental factors shape parenting practices. These insights are crucial for developing culturally adapted parenting education materials and informing interventions that support child development in diverse cultural settings. Full article

With the rapid development of renewable energy and the continuous pursuit of efficient energy utilization, distributed photovoltaic power generation has been widely used in village-level microgrids. As a key platform connecting distributed photovoltaics with users, energy storage systems play an important role in alleviating the imbalance between supply and demand in VMG. However, current energy storage systems rely heavily on lithium batteries, and their frequent charging and discharging processes lead to rapid lifespan decay. To solve this problem, this study proposes a hybrid energy storage system combining supercapacitors and lithium batteries for VMG, and designs a hybrid energy storage scheduling strategy to coordinate the “source–load–storage” resources in the microgrid, effectively cope with power supply fluctuations and slow down the life degradation of lithium batteries. In order to give full play to the active support ability of supercapacitors in suppressing grid voltage and frequency fluctuations, the scheduling optimization goal is set to maximize the sum of the virtual inertia time constants of the supercapacitor. In addition, in order to efficiently solve the high-complexity model, the reason for choosing the snow goose algorithm is that compared with the traditional mathematical programming methods, which are difficult to deal with large-scale uncertain systems, particle swarm optimization, and other meta-heuristic algorithms have insufficient convergence stability in complex nonlinear problems, SGA can balance global exploration and local development capabilities by simulating the migration behavior of snow geese. By improving the convergence effect of SGA and constructing a multi-objective SGA, the effectiveness of the new algorithm, strategy and model is finally verified through three cases, and the loss is reduced by 58.09%, VMG carbon emissions are reduced by 45.56%, and the loss of lithium battery is reduced by 40.49% after active support optimization, and the virtual energy inertia obtained by VMG from supercapacitors during the scheduling cycle reaches a total of 0.1931 s. Full article

Demand response (DR) is increasingly recognized as a critical flexibility resource for modernizing power systems, enabling the large-scale integration of renewable energy and enhancing grid stability. While the field of general electricity load forecasting is supported by numerous systematic reviews, the specific subfield of DR potential forecasting has received comparatively less synthesized attention. This gap leaves a fragmented understanding of modeling techniques, practical implementation challenges, and future research problems for a function that is essential for market participation. To address this, this paper presents a PRISMA-2020-compliant systematic review of 172 studies to comprehensively analyze the state-of-the-art in DR potential estimation. We categorize and evaluate the evolution of forecasting methodologies, from foundational statistical models to advanced AI architectures. Furthermore, the study identifies key technological enablers and systematically maps the persistent technical, regulatory, and behavioral barriers that impede widespread DR deployment. Our analysis demonstrates a clear trend towards hybrid and ensemble models, which outperform standalone approaches by integrating the strengths of diverse techniques to capture complex, nonlinear consumer dynamics. The findings underscore that while technologies like Advanced Metering Infrastructure (AMI) and the Internet of Things (IoT) are critical enablers, the gap between theoretical potential and realized flexibility is primarily dictated by non-technical factors, including inaccurate baseline methodologies, restrictive market designs, and low consumer engagement. This synthesis brings much-needed structure to a fragmented research area, evaluating the current state of forecasting methods and identifying the critical research directions required to improve the operational effectiveness of DR programs. Full article

In this paper, we propose a novel image restoration framework that integrates optimal control techniques with the Hamilton–Jacobi–Bellman (HJB) equation. Motivated by models from production planning, our method restores degraded images by balancing an intervention cost against a state-dependent penalty that quantifies the loss of critical image information. Under the assumption of radial symmetry, the HJB equation is reduced to an ordinary differential equation and solved via a shooting method, from which the optimal feedback control is derived. Numerical experiments, supported by extensive parameter tuning and quality metrics such as PSNR and SSIM, demonstrate that the proposed framework achieves significant improvement in image quality. The results not only validate the theoretical model but also suggest promising directions for future research in adaptive and hybrid image restoration techniques. Full article

The rapid advancement of modern infrastructure and construction industries demands cementitious materials with superior mechanical performance, durability, and sustainability, surpassing the limitations of conventional concrete. To address these challenges, carbon-based nanomaterials—including carbon nanofibers (CNFs), carbon nanotubes (CNTs), and graphene—have gained significant attention as next-generation reinforcement agents due to their exceptional strength, high aspect ratio, and unique interfacial properties. This review presents a critical analysis of the latest technological developments in carbon-enhanced cement and concrete composites, focusing on their role in achieving high-performance construction materials, as there is a shortage of reviews of cement concretes based on carbon nanoadditives. We systematically explore the underlying mechanisms, processing techniques, and structure–property relationships governing carbon-modified cementitious systems. First, we discuss advanced synthesis methods and dispersion strategies for carbon nanomaterials to ensure uniform reinforcement within the cement matrix. Subsequently, we analyze the mechanical enhancement mechanisms, including crack bridging, nucleation seeding, and interfacial bonding, supported by experimental and computational studies. Despite notable progress, challenges such as long-term durability, cost-effectiveness, and large-scale processing remain key barriers to practical implementation. Finally, we outline emerging trends, including multifunctional smart composites and sustainable hybrid systems, to guide future research toward scalable and eco-friendly solutions. By integrating fundamental insights with technological advancements, this review not only advances the understanding of carbon-reinforced cement composites but also provides strategic recommendations for their optimization and industrial adoption in next-generation construction. Full article