Search Results (1,250)

Emissions from civil aviation not only degrade the environmental quality around airports but also have the significant effects on climate change. According to the flight schedules, aircraft/engine combination information and revised emission factors from the International Civil Aviation Organization (ICAO) Aircraft Engine Emission Databank (EEDB) based on meteorological data, the emissions of climate forcers (CFs: BC, CH₄, CO₂, H₂O, and N₂O), conventional air pollutants (CAPs: CO, HC, NO_X, OC, PM_2.5, and SO₂), and hazardous heavy metals (HMs: As, Cu, Ni, Se, Cr, Cd, Hg, Pb, and Zn) from flights of civil aviation of eight airports in Shandong in 2018 and 2020 are estimated in this study. Moreover, the study quantifies the impact of COVID-19 on civil aviation emissions (CFs, CAPs, and HMs) in Shandong, revealing reductions of 47.45%, 48.03%, and 47.45% in 2020 compared to 2018 due to flight cuts. By 2020, total emissions reach 9075.44 kt (CFs), 35.57 kt (CAPs), and 0.51 t (HMs), with top contributors being Qingdao Liuting International Airport (ZSQD) (39.60–40.37%), Shandong Airlines (26.56–28.92%), and B738 aircraft (42.98–46.70%). As byproducts of incomplete fuel combustion, the shares of CO (52.40%) and HC (47.76%) emissions during taxi/ground idle mode are significant. In contrast, emissions during cruise phase are the dominant contributor of other species with a share of 74.67–95.61% of the associated total emissions. The findings highlight the disproportionate role of specific airlines, aircraft, and operational phases in regional aviation pollution. By bridging gaps in localized emission inventories and flight-phase analyses, this research supports targeted mitigation strategies, such as fleet modernization and ground operation optimization, to improve air quality in Shandong. The study highlights how sudden shifts in demand, such as those caused by pandemics, can significantly alter emission profiles, providing insights for sustainable aviation planning. Full article

Introduction: Globally, approximately 53 million children under the age of five live with some form of developmental disability. Exposure to heavy metals has been identified in the literature as a contributing factor in the etiology of neurodevelopmental disorders, however it usually is understudied. Even at low concentrations, these toxicants pose a risk to neurodevelopment, when affecting children early as in the prenatal period. This study aims to systematically review the literature on the associations between exposure to toxic heavy metals and neurodevelopmental outcomes in children. Method: The review was registered at the International Prospective Register of Systematic Review-PROSPERO, under number CRD420250653229 and searches were conducted in the PubMed, Scopus, Web of Science, EMBASE, Lilacs and PsycInfo databases. Results: A total of 68 articles were included, comprising 48 longitudinal studies and 20 cross-sectional studies, published between 2006 and 2025, with a combined sample of 215,195 individuals from 23 countries. Lead was the most consistently investigated metal, appearing in 75% of the studies, followed by mercury, cadmium, and arsenic. Most findings referred to prenatal exposure. Cognitive and motor outcomes were predominantly affected by exposure to Pb and Hg, while behavioral outcomes showed negative associations mainly with Pb and As. Conclusions: The majority of the studies analyzed indicated adverse effects resulting from exposure to heavy metals during pregnancy, especially in the early months, highlighting the vulnerability of the developing brain. Full article

Municipal solid waste incineration fly ash (MSWI FA) is recognized as a hazardous solid waste due to its enrichment in toxic heavy metals and high leaching potential. This review systematically summarizes the current understanding of heavy metal occurrence in MSWI FA and associated environmental risks. Solidification and stabilization methods, such as cement-based curing and chemical immobilization, are widely applied due to their cost-effectiveness and operability, though their long-term stability and recovery potential remain limited. Thermal treatment technologies, including sintering, vitrification, thermal separation, and molten salt processes, have shown excellent performance in reducing volume and enhancing the immobilization or recovery of heavy metals. However, these methods are often limited by high energy demands and operational complexity. Recently, emerging technologies such as electrodialysis, bioleaching, and electrokinetic remediation have demonstrated promising capabilities for selective metal recovery under relatively mild conditions. Nevertheless, these novel approaches remain at an early stage of development and have thus far been validated only at the laboratory or pilot scale. Overall, integrating multiple treatment technologies while advancing resource-oriented and low-carbon approaches will be essential for the sustainable management of MSWI FA. Full article

The MIND diet was designed as an intervention to delay neurodegeneration and has been explored by systematic reviews for associations with cognition and, more recently, cardiometabolic disease. Comparatively less is known about how the MIND diet is associated with other health outcomes (e.g., all-cause mortality, anxiety, insomnia). This scoping review included studies exploring associations between the MIND diet and health outcomes other than cognition and cardiometabolic disease. Online databases were used to identify 4090 studies published between January 2015 and April 2024, from which 47 publications were included for review. Associations between the MIND diet and health outcomes were assessed as either favorable, unfavorable, or having no statistically significant association. Overall, 47 studies were included in this scoping review, 46 were observational, and several were conducted in large, established cohort studies. Across the 47 studies, 18 different topics were explored. Higher adherence to the MIND diet was mostly associated with favorable health outcomes (65%), while roughly one-third (33%) of studies found no statistically significant associations. One study, in Italy, found that increased adherence to the MIND diet was associated with increased exposure to cadmium, a heavy metal. In populations that may benefit from the MIND diet, we recommend additional observational and exploratory studies to identify health associations. Studies exploring educational interventions would help to identify facilitators and barriers to adopting the MIND diet. This scoping review provides some evidence that higher adherence to the MIND diet is associated with risk reduction for many diseases. Further research on environmental exposures (e.g., cadmium) and other deleterious substances absorbed by food crops will be crucial as we strive to enhance health and food security through plant-rich dietary patterns. Full article

Klebsiella pneumoniae is an important pathogen associated with multidrug resistance and virulence in both human and animal populations. While its prevalence and resistance patterns are well documented in clinical settings, data on K. pneumoniae in food-producing animals remain scarce. This study aimed to isolate and characterize multidrug-resistant K. pneumoniae strains from healthy rabbits raised for human consumption, with a focus on antimicrobial resistance genes, plasmid content, and associated mobile genetic elements. A total of 295 fecal samples were collected from rabbits across 20 commercial farms in northern Portugal. Isolates were confirmed using MALDI-TOF MS, tested for hypermucoviscosity, and subjected to antimicrobial susceptibility testing (EUCAST). Whole-genome sequencing (WGS) was performed to determine sequence types (STs), resistance genes, plasmids, and resistance determinants for metals and biocides. Six K. pneumoniae isolates were recovered, showing extensive antimicrobial resistance profiles, including ESBL genes such as bla_CTX-M-15, bla_SHV-28, and bla_TEM-1. The most frequent ST was ST307. Multiple genes resistant to heavy metals were identified. Plasmid analysis revealed the presence of IncFII, IncN, and ColRNAI types. Network analysis showed clusters of genetically related isolates and highlighted shared resistance mechanisms. The presence of multidrug-resistant K. pneumoniae in healthy rabbits destined for human consumption underscores the zoonotic potential of this species and the need for surveillance in the animal–food–human interface. These findings contribute to a better understanding of resistance ecology in the context of One Health. Full article

Decades of unregulated zinc mining activities in the Mae Tao watershed, located in Mae Sot District, Tak Province, northern Thailand, have resulted in the pervasive contamination of agricultural soils with heavy metals, particularly cadmium (Cd), zinc (Zn), lead (Pb), and manganese (Mn). This legacy pollution has significantly impacted multiple environmental compartments—including surface water, groundwater, and sediments—and poses chronic health risks to local populations. This study investigates the key geochemical and physicochemical factors governing the leachability and mobility of these metals from contaminated soils and evaluates the associated human health risks. Controlled leaching experiments demonstrated that ionic strength exerts a more pronounced influence on metal mobilization than pH or other tested variables, suggesting that the electrolyte composition of pore water plays a dominant role in heavy metal transport. Despite elevated total concentrations of Cd, Zn, Pb, and Mn in the soils, hazard quotient (HQ) calculations indicated no significant non-carcinogenic risk under typical exposure scenarios. However, Cd exhibited a carcinogenic risk above the acceptable threshold at both average and peak soil concentrations, underscoring its potential to adversely affect human health. These findings enhance the understanding of heavy metal behavior in contaminated agroecosystems and provide a scientific basis for targeted risk management and long-term monitoring strategies in the Mae Sot region. Full article

Black tea is one of the most widely consumed beverages in the world, second only to water. Its properties are primarily due to the presence of polyphenols, which are associated with various effects, including antioxidant, anticancer, antiviral, and anti-inflammatory activities. These compounds include, among others, theaflavins (TFs) and thearubigins (TRs). The available literature provides numerous reports confirming the positive properties of these compounds. However, it is important to highlight their potential protective effects against oxidative stress induced by heavy metals. This is an important topic, given the ongoing exposure to such pollutants—resulting mainly from industrial development, among other factors. This manuscript provides a summary of the current knowledge on the properties of TFs and TRs and their effect against oxidative stress caused by heavy metals in in vitro studies. The limited amount of research in this area shows that this is still a poorly researched topic. Comparing the results obtained for epigallocatechin gallate (EGCG) from green tea, which has a similar structure to TFs and TRs suggests that they may exhibit similar or even enhanced antioxidant properties. Considering that black tea is consumed much more frequently than green tea worldwide, it is understandable that the antioxidant potential of these two compounds on cells needs to be investigated. Full article

This study provides a comprehensive six-year assessment (2018–2023) of heavy metal contamination in the Romanian Black Sea sector, integrating data from seawater, surface sediments, and benthic mollusks. Sampling was conducted across a broad spatial gradient, including transitional, coastal, shelf, and offshore waters beyond 200 m depth. Concentrations of six potentially toxic metals, including cadmium (Cd), lead (Pb), nickel (Ni), chromium (Cr), copper (Cu), and cobalt (Co), were measured to evaluate regional variability, potential sources, and ecological implications. Results indicate some exceedances of regulatory thresholds for Cd and Pb in transitional and coastal waters, associated with Danube River input and coastal pressures. Seabed substrate analysis revealed widespread enrichment in Ni, moderate levels of Cr, and sporadic Cd elevation in Danube-influenced areas, along with localized hotspots of Cu and Pb near port and industrial zones. Biological uptake patterns in mollusks (bivalves Mytilus galloprovincialis and Anadara inequivalvis and gastropod Rapana venosa) highlighted Cd among key metals of concern, with elevated Bioconcentration Factor (BCF) and Biota–Sediment Accumulation Factor (BAF). Offshore waters generally exhibited lower pollution levels. However, isolated exceedances, such as Cr outliers recorded in 2022, suggest that deep-sea inputs from atmospheric or maritime sources may be both episodic in nature and underrecognized due to limited monitoring coverage. The combined use of water, sediment, and biota data emphasize the strength of multi-matrix approaches in marine pollution evaluation, revealing persistent nearshore pressures and less predictable offshore anomalies. These findings contribute to a more complete understanding of heavy metal distribution in the northwestern Black Sea and provide a scientific basis for improving long-term environmental monitoring and risk management strategies in the region. Full article

This study comprehensively analysed the scientific production of the extraction, characterisation, and toxicological risk of resistant starches obtained from agro-industrial by-products. Articles indexed in the Scopus database between 2015 and 2025 were analysed. The results showed a progressive increase in publications led by Chinese institutions, the most notable being Jiangnan University. Most of the studies were published in high-impact journals, with the International Journal of Biological Macromolecules standing out, followed by Carbohydrate Polymers and Food Chemistry, all in the first quartile. Most studies focused on extraction methods (physical, chemical, and mechanical) and starch characterisation (morphological, structural, molecular, physicochemical, and functional). Emerging trends are directed towards innovative applications such as functional foods. However, the risks associated with contaminants in reusing agro-industrial by-products have not been adequately explored, showing an important gap in the current scientific literature. In this context, future research should focus on evaluating toxicological risks derived from these processes, considering the presence and behaviour of heavy metals, pesticides, and mycotoxins, as well as the possible migration of chemical compounds generated during extraction. Full article

Twenty-nine sediment samples were collected from Hurghada Bay, a highly impacted coastal area along the Northern Red Sea of Egypt, to evaluate environmental quality and human-induced effects on benthic ostracods. As potential bioindicators, benthic ostracods are highly responsive to environmental disturbances, with pollution leading to reduced abundance, lower diversity, and increased opportunistic taxa. To investigate the link between ostracod assemblages and sediment contamination, we measured the concentrations of eight heavy metals (Cu, Cd, Zn, Pb, As, Cr, Ni, and Mn) using inductively coupled plasma–atomic emission spectrometry (ICP-AES). Multivariate statistical analyses identified three distinct ostracod assemblages distributed across three station groups with varying pollution levels. Group I, associated with offshore stations, exhibited low to moderate heavy metal (HM) concentrations and high ostracod abundance and was dominated by Moosella striata, Hiltermannicythere rubrimaris, Ruggieria danielopoli, Neonesidea schulzi, and Paranesidea fracticorallcola, where the water depth and sand content are the main controlling factors. In contrast, Group II, corresponding to stations with the highest HMs and total organic matter (TOM), was dominated by pollution-tolerant species Jugosocythereis borchersi, Cyprideis torosa, Alocopocythere reticulata, and, to a lesser extent, Ghardaglaia triebeli, with reduced ostracod density and diversity. Group III, characterized by stations influenced by the mud-controlling factor, had the lowest HMs and was dominated by pollution-sensitive species Xestoleberis rhomboidei, Paranesidea fortificata, and Loxocorniculum ghardaquensis. These findings highlight the ecological risks posed by HM pollution and emphasize the urgent need for pollution mitigation strategies and continued monitoring to preserve the Red Sea’s benthic biodiversity. Full article

Inland aquatic ecosystems, encompassing lakes, reservoirs, and ponds, serve as vital repositories of water resources and provide essential ecological, social, and cultural services. Water color, a key indicator of water quality, reflects the complex interactions among physicochemical, biological, and environmental drivers. Heilong Pool (HP) in Southwest China, which consists of a Clear Pool (CP) and a Turbid Pool (TP), has recently exhibited an anomalous reddish-brown “pumpkin soup” phenomenon in the CP, while the TP remains unchanged. This unusual phenomenon has raised widespread public concern regarding water resource security and its potential association with geological disasters. To elucidate the ecological and geochemical mechanisms of this phenomenon, we employed a multifaceted analytical approach that included assessing nutrient elements, quantifying heavy metal concentrations, analyzing dissolved substances, characterizing algal community composition, and applying δD-δ¹⁸O isotope analytical models. Our findings illustrated that while Bacillariophyta predominate (>79.3% relative abundance) in the algal community of HP, they were not the primary determinant of water color changes. Instead, Fe(OH)₃ colloidal particles, originating from groundwater–surface water interactions and controlled by redox environment dynamics periodically, emerged as the principal factors of the reddish-brown discoloration. The genesis of the “pumpkin soup” water coloration was attributed to the precipitation-induced displacement of anoxic groundwater from confined karst conduits. Subsequent exfiltration and atmospheric exposure facilitate oxidative precipitation, forming authigenic rust-hued Fe(OH)₃ colloidal complexes. This study provides new insights into the geochemical and hydrological mechanisms underlying water color anomalies in karst-dominated catchments. Full article

Staphylococcus shinii (S. shinii) is a coagulase-negative species primarily associated with the degradation of organic matter, contributing to nutrient cycling in natural environments. This species has been mainly studied in clinical and terrestrial contexts, with no previous reports of its presence in marine environments. In this study, we report the first isolation of S. shinii from a marine habitat. The strain SC-M1C was isolated from the Red Sea sponge Negombata magnifica. Whole-genome sequencing confirmed its taxonomic identity as S. shinii. The genome uncovers potential adaptive characteristics that facilitate survival in marine ecosystems, comprising genes associated with osmoregulation, nutrient acquisition, stress response, and resistance to heavy metals. Moreover, multiple genomic islands and plasmids were identified, suggesting a potential role in horizontal gene transfer and environmental adaptability. The presence of biosynthetic gene clusters linked to non-ribosomal peptides, siderophores, and terpene production indicates potential for biochemical versatility beyond traditional metabolic expectations. This study presents the first genomic insights into S. shinii in a marine context, highlighting its ecological significance and adaptive mechanisms in a high-salinity environment. These findings expand our understanding of staphylococcal ecology beyond terrestrial and clinical origins and provide a foundation for exploring the role of S. shinii in marine microbial interactions and environmental resilience. Full article

The natural resistance-associated macrophage proteins (NRAMPs) gene family represents a group of membrane transporter proteins with wide distribution in plants. This family of membrane transporters plays a pivotal role in mediating plant responses to metal stress by coordinating ion transport processes and maintaining cellular metal homeostasis, thereby effectively mitigating the detrimental effects of metal ion stress on plant growth and development. This study conducted a comprehensive genome-wide analysis of the NRAMP gene family in A. tauschii using integrated bioinformatics approaches, as well as the expression pattern when exposed to heavy metal-induced stress. By means of phylogenetic investigation, eleven AetNRAMP proteins were categorized into five distinct subgroups. Quantitative reverse transcription polymerase chain reaction (qRT-PCR) analysis revealed that the majority of NRAMP genes exhibited marked differential expression patterns under specific stress treatments. Subsequently, yeast cells were employed to validate the functions of AetNRAMP1 and AetNRAMP3. It was confirmed that AetNRAMP1 functioned in copper transport, and AetNRAMP3 showed an increase in its expression level under manganese stress. These findings establish a molecular foundation for elucidating the functional specialization of NRAMP gene family members in A. tauschii’s heavy metal detoxification pathways, providing critical genetic evidence for their stress-responsive regulatory networks. Nevertheless, significant knowledge gaps persist regarding its functions in A. tauschii. Research on metal stress resistance in this wheat progenitor species may establish a theoretical foundation for enhancing wheat tolerance and developing improved cultivars. Full article

Coal serves as the primary energy source for China, with production anticipated to reach 4.76 billion tons in 2024. However, the mining process generates a significant amount of gangue, with approximately 800 million tons produced in 2023 alone. Currently, China faces substantial gangue stockpiles, characterized by a low comprehensive utilization rate that fails to meet the country’s ecological and environmental protection requirements. The environmental challenges posed by the treatment and disposal of gangue are becoming increasingly severe. This review employs bibliometric analysis and theoretical perspectives to examine the latest advancements in gangue utilization, specifically focusing on the application of computational chemistry to elucidate the structural features and interaction mechanisms of coal gangue, and to collate how these insights have been leveraged in the literature to inform its potential utilization routes. The aim is to promote the effective resource utilization of this material, and key topics discussed include evaluating the risks of spontaneous combustion associated with gangue, understanding the mechanisms governing heavy metal migration, and modifying coal byproducts to enhance both economic viability and environmental sustainability. The case studies presented in this article offer valuable insights into the gangue conversion process, contributing to the development of more efficient and eco-friendly methods. By proposing a theoretical framework, this review will support ongoing initiatives aimed at the sustainable management and utilization of coal gangue, emphasizing the critical need for continued research and development in this vital area. This review uniquely combines bibliometric analysis with computational chemistry to identify new trends and gaps in coal waste utilization, providing a roadmap for future research. Full article

Wild edible mushrooms are increasingly recognised for their nutritional and therapeutic potential, owing to their richness in bioactive compounds and antioxidant properties. This study assessed the chemical composition, antioxidant capacity, and bioaccumulation of heavy metals (Cd, Pb, Ni) in Boletus edulis, Imleria badia, and Leccinum scabrum collected from two forested regions of north-western Poland differing in anthropogenic influence and soil characteristics. The analysis encompassed structural polysaccharides (β- and α-glucans, chitin), carotenoids, L-ascorbic acid, phenolic and organic acids. B. edulis exhibited the highest β-glucan and lycopene contents, but also the greatest cadmium accumulation. I. badia was distinguished by elevated ascorbic and citric acid levels and the strongest DPPH radical scavenging activity, while L. scabrum showed the highest ABTS and FRAP antioxidant capacities and accumulated quinic acid and catechin. Principal component analysis indicated strong correlations between antioxidant activity and phenolic acids, while cadmium levels were inversely associated with antioxidant potential and positively correlated with chitin. Although all metal concentrations remained within EU food safety limits, B. edulis showed consistent cadmium bioaccumulation. From a practical perspective, the results highlight the importance of species selection and sourcing location when considering wild mushrooms for consumption or processing, particularly in the context of nutritional value and contaminant load. Importantly, regular or excessive consumption of B. edulis may result in exceeding the tolerable weekly intake (TWI) levels for cadmium and nickel, which warrants particular attention from a food safety perspective. These findings underscore the influence of species-specific traits and environmental conditions on mushroom biochemical profiles and support their potential as functional foods, provided that metal contents are adequately monitored. Full article