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Search Results (1,729)

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Keywords = healthcare machine learning

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16 pages, 1543 KB  
Article
Inferring Mental States via Linear and Non-Linear Body Movement Dynamics: A Pilot Study
by Tad T. Brunyé, Kana Okano, James McIntyre, Madelyn K. Sandone, Lisa N. Townsend, Marissa Marko Lee, Marisa Smith and Gregory I. Hughes
Sensors 2025, 25(22), 6990; https://doi.org/10.3390/s25226990 (registering DOI) - 15 Nov 2025
Abstract
Stress, workload, and uncertainty characterize occupational tasks across sports, healthcare, military, and transportation domains. Emerging theory and empirical research suggest that coordinated whole-body movements may reflect these transient mental states. Wearable sensors and optical motion capture offer opportunities to quantify such movement dynamics [...] Read more.
Stress, workload, and uncertainty characterize occupational tasks across sports, healthcare, military, and transportation domains. Emerging theory and empirical research suggest that coordinated whole-body movements may reflect these transient mental states. Wearable sensors and optical motion capture offer opportunities to quantify such movement dynamics and classify mental states that influence occupational performance and human–machine interaction. We tested this possibility in a small pilot study (N = 10) designed to test feasibility and identify preliminary movement features linked to mental states. Participants performed a perceptual decision-making task involving facial emotion recognition (i.e., deciding whether depicted faces were happy versus angry) with variable levels of stress (via a risk of electric shock), workload (via time pressure), and uncertainty (via visual degradation of task stimuli). The time series of movement trajectories was analyzed both holistically (full trajectory) and by phase: lowered (early), raising (middle), aiming (late), and face-to-face (sequential). For each epoch, up to 3844 linear and non-linear features were extracted across temporal, spectral, probability, divergence, and fractal domains. Features were entered into a repeated 10-fold cross-validation procedure using 80/20 train/test splits. Feature selection was conducted with the T-Rex Selector, and selected features were used to train a scikit-learn pipeline with a Robust Scaler and a Logistic Regression classifier. Models achieved mean ROC AUC scores as high as 0.76 for stress classification, with the highest sensitivity during the full movement trajectory and middle (raise) phases. Classification of workload and uncertainty states was less successful. These findings demonstrate the potential of movement-based sensing to infer stress states in applied settings and inform future human–machine interface development. Full article
(This article belongs to the Special Issue Sensors and Data Analysis for Biomechanics and Physical Activity)
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19 pages, 1357 KB  
Article
Clustered Federated Learning with Adaptive Similarity for Non-IID Data
by Guodong Yi, Zhouyang Wu, Xinyu Zhang and Xiaocui Li
Electronics 2025, 14(22), 4454; https://doi.org/10.3390/electronics14224454 - 14 Nov 2025
Abstract
Federated learning (FL) offers a distributed approach for the collaborative training of machine learning models across decentralized clients while safeguarding data privacy. This characteristic makes FL well suited for privacy-sensitive fields such as healthcare and finance. However, addressing the heterogeneity caused by nonindependent [...] Read more.
Federated learning (FL) offers a distributed approach for the collaborative training of machine learning models across decentralized clients while safeguarding data privacy. This characteristic makes FL well suited for privacy-sensitive fields such as healthcare and finance. However, addressing the heterogeneity caused by nonindependent and identically distributed (non-IID) data remains a significant challenge for traditional FL methods. To address these issues, the enhancing clustered federated learning with adaptive similarity (AS-CFL) algorithm, which dynamically forms client clusters based on model update similarity and uses a forward-incentive mechanism to improve collaborative training efficiency among similar clients, is proposed in this study. Experimental results on the MNIST and EMNIST datasets reveal that compared with baseline methods such as the CFL, IFCA, and FedAvg models, the AS-CFL algorithm achieves faster convergence—reducing the number of communication rounds by approximately 20%—while maintaining competitive accuracy, demonstrating its effectiveness in heterogeneous FL scenarios. Full article
(This article belongs to the Special Issue Digital Intelligence Technology and Applications, 2nd Edition)
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21 pages, 341 KB  
Article
Synthetic Data Generation for Binary and Multi-Class Classification in the Health Domain
by Camila Guerreiro, Fátima Leal and Micaela Pinho
Information 2025, 16(11), 986; https://doi.org/10.3390/info16110986 - 14 Nov 2025
Abstract
The growing demand for data-driven solutions in healthcare is often hindered by limited access to high-quality datasets due to privacy concerns, data imbalance, and regulatory constraints. Synthetic data generation has emerged as a promising strategy to address these challenges by creating artificial yet [...] Read more.
The growing demand for data-driven solutions in healthcare is often hindered by limited access to high-quality datasets due to privacy concerns, data imbalance, and regulatory constraints. Synthetic data generation has emerged as a promising strategy to address these challenges by creating artificial yet statistically valid datasets that preserve the underlying patterns of real data without compromising patient confidentiality. This study explores methodologies for generating synthetic data tailored to binary and multi-class classification problems within the health domain. We employ advanced techniques such as probabilistic modelling, generative adversarial networks, and data augmentation strategies to replicate realistic feature distributions and class relationships. A comprehensive evaluation is conducted using benchmark healthcare datasets, measuring fidelity, diversity, and utility of the synthetic data in downstream predictive modelling tasks. The original dataset consisted of 2125 imbalanced cases, both in the binary and multi-class classification scenarios. Experimental results demonstrate that models trained on synthetic datasets achieve performance levels comparable to those trained on real data, particularly in scenarios with severe class imbalance. The findings underscore the potential of synthetic data as a privacy-preserving enabler for robust machine learning applications in healthcare, facilitating innovation while adhering to strict data protection regulations. Full article
22 pages, 1545 KB  
Article
An Explainable Ensemble and Deep Learning Framework for Accurate and Interpretable Parkinson’s Disease Detection from Voice Biomarkers
by Suliman Aladhadh
Diagnostics 2025, 15(22), 2892; https://doi.org/10.3390/diagnostics15222892 - 14 Nov 2025
Abstract
Background: Parkinson’s disease (PD) is a degenerative neurological disorder that greatly affects motor and speech functions; therefore, early diagnosis is vital for improving patients’ quality of life. This work introduces a unified and explainable AI framework for PD detection that integrates ensemble [...] Read more.
Background: Parkinson’s disease (PD) is a degenerative neurological disorder that greatly affects motor and speech functions; therefore, early diagnosis is vital for improving patients’ quality of life. This work introduces a unified and explainable AI framework for PD detection that integrates ensemble and deep learning models with transparent interpretability techniques. Methods: Acoustic features were extracted from the Parkinson's Voice Disorder Dataset, and a broad suite of machine learning and deep learning models was evaluated, including traditional classifiers (Logistic Regression, Decision Tree, KNN, Linear Regression, SVM), ensemble methods (Random Forest, Gradient Boosting, XGBoost, LightGBM), and neural architectures (CNN, LSTM, GAN). Results: The ensemble methods—specifically LightGBM (LGBM) and Random Forest (RF)—achieved the best performance, reaching state-of-the-art accuracy (98.01%) and ROC-AUC (0.9914). Deep learning models like CNN and GAN produced competitive results, validating their ability to capture nonlinear and generative voice patterns. XAI analysis revealed that nonlinear acoustic biomarkers such as spread2, PPE, and RPDE are the most influential predictors, consistent with clinical evidence of dysphonia in PD. Conclusions: The proposed framework achieves a strong balance between predictive accuracy and interpretability, representing a clinically relevant, scalable, and non-invasive solution for early Parkinson’s detection. Full article
(This article belongs to the Special Issue Machine-Learning-Based Disease Diagnosis and Prediction)
72 pages, 9140 KB  
Review
Bridging Signal Intelligence and Clinical Insight: A Comprehensive Review of Feature Engineering, Model Interpretability, and Machine Learning in Biomedical Signal Analysis
by Ali Mohammad Alqudah and Zahra Moussavi
Appl. Sci. 2025, 15(22), 12036; https://doi.org/10.3390/app152212036 - 12 Nov 2025
Viewed by 148
Abstract
Biomedical signal analysis underpins modern healthcare by enabling accurate diagnosis, continuous physiological monitoring, and informed patient management. While deep learning excels at automated feature extraction and end-to-end modeling, classical ML remains essential for tasks requiring interpretability, data efficiency, and clinical transparency. This review [...] Read more.
Biomedical signal analysis underpins modern healthcare by enabling accurate diagnosis, continuous physiological monitoring, and informed patient management. While deep learning excels at automated feature extraction and end-to-end modeling, classical ML remains essential for tasks requiring interpretability, data efficiency, and clinical transparency. This review synthesizes advances in ML methods including Support Vector Machines, Random Forests, and Decision Trees focusing on physiologically informed feature engineering, robust feature selection, and meaningful model interpretation. We provide guidelines for signal preprocessing, domain-specific feature extraction, and selection strategies across standard biomedical signals such as electrocardiograms (ECGs), electromyograms (EMGs), electroencephalograms (EEGs), Electrovestibulography (EVestG), and tracheal breathing sounds (TBSs). Reviewing TBS studies illustrates an end-to-end workflow highlighting common features and classifiers alongside practical challenges and solutions. Reported ML application performance ranges from 85 to 94% accuracy for EEG, ECG, and EMG, to 82% specificity for TBSs, emphasizing the trade-off between interpretability and predictive performance. Marginal accuracy gains alone do not constitute meaningful progress unless they enhance clinical insight, actionable decision-making, or model transparency. Finally, we compare ML with DL, discuss strengths and limitations, and provide recommendations and future directions for developing robust, interpretable, and clinically relevant biomedical ML. Full article
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30 pages, 2068 KB  
Article
Ethical AI in Healthcare: Integrating Zero-Knowledge Proofs and Smart Contracts for Transparent Data Governance
by Mohamed Ezz, Alaa S. Alaerjan and Ayman Mohamed Mostafa
Bioengineering 2025, 12(11), 1236; https://doi.org/10.3390/bioengineering12111236 - 12 Nov 2025
Viewed by 290
Abstract
In today’s rapidly advancing healthcare landscape, integrating Artificial Intelligence (AI) and Machine Learning (ML) has the potential to significantly improve patient care and streamline medical processes. The utilization of confidential patient data to train and develop these technologies, however, raises significant concerns regarding [...] Read more.
In today’s rapidly advancing healthcare landscape, integrating Artificial Intelligence (AI) and Machine Learning (ML) has the potential to significantly improve patient care and streamline medical processes. The utilization of confidential patient data to train and develop these technologies, however, raises significant concerns regarding authenticity, security, and privacy. In this study, we introduce MediChainAI, a safe and practical framework that allows patients full ownership over their own health data by integrating Self-Sovereign Identity (SSI), Blockchain, and sophisticated cryptography techniques. By clearly outlining the goals and parameters of this access, MediChainAI allows patients to safely and selectively share data with healthcare providers and researchers. While SSI guarantees that patients have ownership of their data, the framework uses Blockchain technology to keep things transparent and secure. Further, MediChainAI makes use of Merkle trees, which provide verified access to subsets of data without jeopardizing the privacy of the whole dataset. The encryption mechanism, which is based on smart contracts, is a distinctive feature of the framework that allows researchers and medical practitioners controlled and secure access to patient data. In order to improve the accuracy and reliability of medical diagnoses and treatment, this strategy makes sure that only confirmed, legitimate data is utilized to train medical models. A significant step toward safer and more personalized healthcare, MediChainAI encourages ethical and patient-focused innovation by effectively resolving essential issues regarding data security and patient privacy. Full article
(This article belongs to the Section Biosignal Processing)
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22 pages, 683 KB  
Article
LatAtk: A Medical Image Attack Method Focused on Lesion Areas with High Transferability
by Long Li, Yibo Huang, Chong Li, Fei Zhou, Jingjing Li and Kamarul Hawari Ghazali
J. Imaging 2025, 11(11), 404; https://doi.org/10.3390/jimaging11110404 - 11 Nov 2025
Viewed by 148
Abstract
The rise in trusted machine learning has prompted concerns about the security, reliability and controllability of deep learning, especially when it is applied to sensitive areas involving life and health safety. To thoroughly analyze potential attacks and promote innovation in security technologies for [...] Read more.
The rise in trusted machine learning has prompted concerns about the security, reliability and controllability of deep learning, especially when it is applied to sensitive areas involving life and health safety. To thoroughly analyze potential attacks and promote innovation in security technologies for DNNs, this paper conducts research on adversarial attacks against medical images and proposes a medical image attack method that focuses on lesion areas and has good transferability, named LatAtk. First, based on the image segmentation algorithm, LatAtk divides the target image into an attackable area (lesion area) and a non-attackable area and injects perturbations into the attackable area to disrupt the attention of the DNNs. Second, a class activation loss function based on gradient-weighted class activation mapping is proposed. By obtaining the importance of features in images, the features that play a positive role in model decision-making are further disturbed, making LatAtk highly transferable. Third, a texture feature loss function based on local binary patterns is proposed as a constraint to reduce the damage to non-semantic features, effectively preserving texture features of target images and improving the concealment of adversarial samples. Experimental results show that LatAtk has superior aggressiveness, transferability and concealment compared to advanced baselines. Full article
(This article belongs to the Section Medical Imaging)
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19 pages, 690 KB  
Systematic Review
Multimodal Models in Healthcare: Methods, Challenges, and Future Directions for Enhanced Clinical Decision Support
by Md Kamrul Siam, Md Jobair Hossain Faruk, Bofan He, Jerry Q. Cheng and Huanying Gu
Information 2025, 16(11), 971; https://doi.org/10.3390/info16110971 - 10 Nov 2025
Viewed by 420
Abstract
Decision-making in modern healthcare increasingly relies on integrating a variety of data sources, including patient demographics, medical imaging, laboratory results, clinical narratives, and temporal data, all of which are difficult for traditional computational methodologies to accurately predict. This paper evaluates the latest methodologies [...] Read more.
Decision-making in modern healthcare increasingly relies on integrating a variety of data sources, including patient demographics, medical imaging, laboratory results, clinical narratives, and temporal data, all of which are difficult for traditional computational methodologies to accurately predict. This paper evaluates the latest methodologies that integrate diverse data types, including photographs, clinical notes, temporal measurements, and structured tables, through techniques such as feature amalgamation, prioritization of essential information, and utilization of graphs. We also assess pre-training, fine-tuning, and comprehensive evaluation of model generation procedures. By synthesizing findings from 50 of 91 peer-reviewed papers published between 2020 and 2024, we demonstrate that the integration of structured and unstructured data significantly improves performance in tasks like diagnosis, prognosis prediction, and personalized treatment. This review combines substantial multimodal datasets and applications across several therapeutic domains while addressing critical issues such as data heterogeneity, scalability, interpretability, and ethical considerations. This paper highlights the transformative potential of multimodal models in improving clinical decision support, providing a framework for future research to advance precision medicine and enhance healthcare outcomes. Full article
(This article belongs to the Special Issue Artificial Intelligence-Based Digital Health Emerging Technologies)
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23 pages, 1693 KB  
Article
Machine Learning Pipeline for Early Diabetes Detection: A Comparative Study with Explainable AI
by Yas Barzegar, Atrin Barzegar, Francesco Bellini, Fabrizio D'Ascenzo, Irina Gorelova and Patrizio Pisani
Future Internet 2025, 17(11), 513; https://doi.org/10.3390/fi17110513 - 10 Nov 2025
Viewed by 150
Abstract
The use of Artificial Intelligence (AI) in healthcare has significantly advanced early disease detection, enabling timely diagnosis and improved patient outcomes. This work proposes an end-to-end machine learning (ML) model for predicting diabetes based on data quality by following key steps, including advanced [...] Read more.
The use of Artificial Intelligence (AI) in healthcare has significantly advanced early disease detection, enabling timely diagnosis and improved patient outcomes. This work proposes an end-to-end machine learning (ML) model for predicting diabetes based on data quality by following key steps, including advanced preprocessing by KNN imputation, intelligent feature selection, class imbalance with a hybrid approach of SMOTEENN, and multi-model classification. We rigorously compared nine ML classifiers, namely ensemble approaches (Random Forest, CatBoost, XGBoost), Support Vector Machines (SVM), and Logistic Regression (LR) for the prediction of diabetes disease. We evaluated performance on specificity, accuracy, recall, precision, and F1-score to assess generalizability and robustness. We employed SHapley Additive exPlanations (SHAP) for explainability, ranking, and identifying the most influential clinical risk factors. SHAP analysis identified glucose levels as the dominant predictor, followed by BMI and age, providing clinically interpretable risk factors that align with established medical knowledge. Results indicate that ensemble models have the highest performance among the others, and CatBoost performed the best, which achieved an ROC-AUC of 0.972, an accuracy of 0.968, and an F1-score of 0.971. The model was successfully validated on two larger datasets (CDC BRFSS and a 130-hospital dataset), confirming its generalizability. This data-driven design provides a reproducible platform for applying useful and interpretable ML models in clinical practice as a primary application for future Internet-of-Things-based smart healthcare systems. Full article
(This article belongs to the Special Issue The Future Internet of Medical Things, 3rd Edition)
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27 pages, 2824 KB  
Article
Identifying Predictors of Utilization of Skilled Birth Attendance in Uganda Through Interpretable Machine Learning
by Shaheen M. Z. Memon, Robert Wamala and Ignace H. Kabano
Int. J. Environ. Res. Public Health 2025, 22(11), 1691; https://doi.org/10.3390/ijerph22111691 - 9 Nov 2025
Viewed by 243
Abstract
Skilled Birth Attendance (SBA) is essential for reducing maternal and neonatal mortality, yet access remains limited in many low- and middle-income countries. This study used machine learning to predict SBA use among Ugandan women and identify key influencing factors. We analyzed data from [...] Read more.
Skilled Birth Attendance (SBA) is essential for reducing maternal and neonatal mortality, yet access remains limited in many low- and middle-income countries. This study used machine learning to predict SBA use among Ugandan women and identify key influencing factors. We analyzed data from the 2016 Uganda Demographic and Health Survey, focusing on women aged 15 to 49 who had given birth in the preceding five years. After preparing and selecting relevant features, six tree-based models (decision tree, random forest, gradient boosting, XGBoost, LightGBM, CatBoost) and logistic regression were applied. Class imbalance was addressed using cost-sensitive learning, and hyperparameters were tuned via Bayesian optimization. XGBoost performed best (F1-score: 0.52; recall: 0.73; AUC: 0.75). SHapley Additive Explanations (SHAP) were used to interpret model predictions. Key predictors of SBA use included education level, antenatal care visits, region (especially Northern Uganda), perceived distance to a healthcare facility, and urban or rural residence. The results demonstrate the value of interpretable machine learning for identifying at-risk populations and guiding targeted maternal health interventions in Uganda. Full article
(This article belongs to the Section Global Health)
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21 pages, 10260 KB  
Article
Machine Learning for Enabling High-Data-Rate Secure Random Communication: SVM as the Optimal Choice over Others
by Areeb Ahmed and Zoran Bosnić
Mathematics 2025, 13(22), 3590; https://doi.org/10.3390/math13223590 - 8 Nov 2025
Viewed by 231
Abstract
Machine learning (ML) has become a key ingredient in revolutionizing the physical layer security of next-generation devices across Industry 4.0, healthcare, and communication networks. Many conventional and unconventional communication architectures now incorporate ML algorithms for performance and security enhancement. In this study, we [...] Read more.
Machine learning (ML) has become a key ingredient in revolutionizing the physical layer security of next-generation devices across Industry 4.0, healthcare, and communication networks. Many conventional and unconventional communication architectures now incorporate ML algorithms for performance and security enhancement. In this study, we propose an unconventional, high-data-rate, machine-learning-driven, secure random communication system (HDR-MLRCS). Instead of utilizing traditional static methods to encrypt and decrypt alpha-stable (α-stable) noise as a random carrier, we integrated several ML algorithms to convey binary information to the intended receivers covertly. A support vector machine-aided receiver (SVM-R), Naïve Bayes-aided receiver (NB-R), k-Nearest Neighbor-aided receiver (kNN-R), and decision tree-aided receiver (DT-R) were integrated into a single architecture to provide an accelerated data rate with robust security. All intended receivers were pre-trained on a restricted-access dataset (R- Full article
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33 pages, 6166 KB  
Article
A Hybrid MCDM and Machine Learning Framework for Thalassemia Risk Assessment in Pregnant Women
by Shefayatuj Johara Chowdhury, Tanjim Mahmud, Farzana Tasnim, Sanjida Sharmin, Saida Nawal, Umme Habiba Papri, Samia Afreen Dolon, Md. Eftekhar Alam, Mohammad Shahadat Hossain and Karl Andersson
Diagnostics 2025, 15(22), 2833; https://doi.org/10.3390/diagnostics15222833 - 8 Nov 2025
Viewed by 520
Abstract
Background: Thalassemia has been recognized as a critical public health issue in Bangladesh, especially among pregnant women, due to its hereditary nature and the lack of early screening infrastructure. Early identification of at-risk individuals is essential to prevent the transmission of this genetic [...] Read more.
Background: Thalassemia has been recognized as a critical public health issue in Bangladesh, especially among pregnant women, due to its hereditary nature and the lack of early screening infrastructure. Early identification of at-risk individuals is essential to prevent the transmission of this genetic disorder to future generations and to reduce the burden on an already strained healthcare system. Methods: In this study, an innovative framework for thalassemia risk assessment has been developed by integrating Multi-Criteria Decision-Making (MCDM) methods—specifically AHP-TOPSIS—with machine learning algorithms including Random Forest, XGBoost, and CatBoost. Explainable Artificial Intelligence (XAI) techniques such as SHAP and LIME have also been incorporated to improve model transparency and trustworthiness. Real-world clinical and demographic data, consisting of 16 features and 1200 samples, have been collected through a structured survey and processed using rigorous feature selection and ranking methods. Risk stratification has been performed to classify patients into high, medium, and low categories, enabling targeted intervention. Results: Among all models, the XGBoost classifier trained on AHP–TOPSIS–prioritized features achieved a consistent accuracy of 99.28% under stratified 20-fold cross-validation, demonstrating robust diagnostic classification performance. The model predominantly captures hematologic patterns characteristic of thalassemia manifestations, functioning as an assistive diagnostic framework rather than a causal risk predictor. The explainability of predictions, ensured through comprehensive visual and statistical analyses, further enhances the model’s clinical transparency and reliability. Conclusions: The proposed MCDM–machine learning framework demonstrates strong potential for improving thalassemia risk assessment, enabling early detection and informed decision-making in maternal healthcare. The proposed framework should be regarded as a preliminary proof-of-concept system that demonstrates the feasibility of integrating Multi-Criteria Decision-Making (AHP–TOPSIS) with advanced machine learning and explainable-AI techniques for thalassemia assessment. Although the model achieved strong diagnostic performance under nested cross-validation, additional external validation and inclusion of causal predictors are required before clinical deployment. Full article
(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
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37 pages, 4859 KB  
Review
Eyes of the Future: Decoding the World Through Machine Vision
by Svetlana N. Khonina, Nikolay L. Kazanskiy, Ivan V. Oseledets, Roman M. Khabibullin and Artem V. Nikonorov
Technologies 2025, 13(11), 507; https://doi.org/10.3390/technologies13110507 - 7 Nov 2025
Viewed by 1158
Abstract
Machine vision (MV) is reshaping numerous industries by giving machines the ability to understand what they “see” and respond without human intervention. This review brings together the latest developments in deep learning (DL), image processing, and computer vision (CV). It focuses on how [...] Read more.
Machine vision (MV) is reshaping numerous industries by giving machines the ability to understand what they “see” and respond without human intervention. This review brings together the latest developments in deep learning (DL), image processing, and computer vision (CV). It focuses on how these technologies are being applied in real operational environments. We examine core methodologies such as feature extraction, object detection, image segmentation, and pattern recognition. These techniques are accelerating innovation in key sectors, including healthcare, manufacturing, autonomous systems, and security. A major emphasis is placed on the deepening integration of artificial intelligence (AI) and machine learning (ML) into MV. We particularly consider the impact of convolutional neural networks (CNNs), generative adversarial networks (GANs), and transformer architectures on the evolution of visual recognition capabilities. Beyond surveying advances, this review also takes a hard look at the field’s persistent roadblocks, above all the scarcity of high-quality labeled data, the heavy computational load of modern models, and the unforgiving time limits imposed by real-time vision applications. In response to these challenges, we examine a range of emerging fixes: leaner algorithms, purpose-built hardware (like vision processing units and neuromorphic chips), and smarter ways to label or synthesize data that sidestep the need for massive manual operations. What distinguishes this paper, however, is its emphasis on where MV is headed next. We spotlight nascent directions, including edge-based processing that moves intelligence closer to the sensor, early explorations of quantum methods for visual tasks, and hybrid AI systems that fuse symbolic reasoning with DL, not as speculative futures but as tangible pathways already taking shape. Ultimately, the goal is to connect cutting-edge research with actual deployment scenarios, offering a grounded, actionable guide for those working at the front lines of MV today. Full article
(This article belongs to the Section Information and Communication Technologies)
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30 pages, 3314 KB  
Article
Spatio-Temporal Variability and Environmental Associations of Emergency Department Demand: A Longitudinal Analysis in Zaragoza, Spain (2011–2024)
by Jorge Blanco Prieto, Marina Ferreras González and Oscar Cosido Cobos
ISPRS Int. J. Geo-Inf. 2025, 14(11), 439; https://doi.org/10.3390/ijgi14110439 - 7 Nov 2025
Viewed by 253
Abstract
Emergency department (ED) overcrowding has become a critical public health issue worldwide, driven by increasing demand and limited healthcare resources. This study analyzes the spatio-temporal variability of ED visits at Royo Villanova Hospital (Zaragoza, Spain) from 2011 to 2024, integrating clinical, demographic, environmental, [...] Read more.
Emergency department (ED) overcrowding has become a critical public health issue worldwide, driven by increasing demand and limited healthcare resources. This study analyzes the spatio-temporal variability of ED visits at Royo Villanova Hospital (Zaragoza, Spain) from 2011 to 2024, integrating clinical, demographic, environmental, and socioeconomic data. Using geospatial tools and machine learning models (XGBoost with SHAP interpretation), we identify key patterns in ED demand across time and space. Results show that the hour of the day is the most influential variable across all diagnoses, while temperature, humidity, and air pollutants (NO2, SO2, O3) significantly affect respiratory and injury-related visits. Spatial analysis reveals persistent high-demand clusters in specific health zones, with proximity to the hospital playing a major role. The COVID-19 pandemic caused structural shifts in demand, particularly in pediatric care. Our findings highlight the need for tailored, diagnosis-specific predictive models and support the use of geospatial and environmental data for proactive ED resource planning. This approach enhances the capacity of health systems to anticipate demand surges and allocate resources efficiently. Full article
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23 pages, 2283 KB  
Article
Cuff-Less Estimation of Blood Pressure and Detection of Hypertension/Arteriosclerosis from Fingertip PPG Using Machine Learning: An Experimental Study
by Marco Antonio Arroyo-Ramírez, Isaac Machorro-Cano, Augusto Javier Reyes-Delgado, Jorge Ernesto González-Díaz and José Luis Sánchez-Cervantes
Appl. Sci. 2025, 15(21), 11829; https://doi.org/10.3390/app152111829 - 6 Nov 2025
Viewed by 344
Abstract
Worldwide less than half of adults with hypertension are diagnosed and treated (only 42%), in addition one in five adults with hypertension (21%) has the condition under control. In the American continent, cardiovascular diseases (CVD) are the leading cause of death and high [...] Read more.
Worldwide less than half of adults with hypertension are diagnosed and treated (only 42%), in addition one in five adults with hypertension (21%) has the condition under control. In the American continent, cardiovascular diseases (CVD) are the leading cause of death and high blood pressure (hypertension) is responsible for 50% of CVD deaths. Only a few countries show a population hypertension control rate of more than 50%. In this experimental study, we trained 15 regression-type machine learning algorithms, including traditional and ensemble methods to assess their effectiveness in estimating arterial pressure using noninvasive photoplethysmographic (PPG) signals extracted from 110 study subjects, to identify the risk of hypertension and its correlation with arteriosclerosis. We analyzed the performance of each algorithm using the metrics MSE, MAE, RMSE, and r2. A 10-fold cross-validation showed that the best algorithms for hypertension risk identification were LR, KNN, SVR, RF, LR Baggin, KNNBagging, SVRBagging, and DTBagging. On the other hand, the best algorithms for arterioclesrosis risk identification were LR, KNN, SVR, RF, LR Bagging, and DTBagging. These results suggest that this research is promising and offers valuable information on the acquisition and processing of PPG signals. However, as this is an experimental study, the effectiveness of our model needs to be validated with a larger database. On the other hand, this model represents a support tool for healthcare specialists in the early detection of cardiovascular health, allowing people to self-manage their health and seek medical attention at an early stage. Full article
(This article belongs to the Special Issue Data Science for Human Health Monitoring with Smart Sensors)
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