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Search Results (94)

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Keywords = health and well-being lifestyle older adults

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12 pages, 1178 KiB  
Systematic Review
Exploring the Preventive Effects of Omega-3 Polyunsaturated Fatty Acids Supplementation on Global Cognition: A Systematic Review and Meta-Analysis of Cognitively Unimpaired Older Adults
by Roberta Mulargia, Federica Ribaldi, Sophie Mutel, Ozge Sayin, Giorgi Khachvani, Gabriele Volpara, Giulia Remoli, Umberto Nencha, Stefano Gianonni-Luza, Stefano Cappa, Giovanni B. Frisoni and Augusto J. Mendes
Clin. Transl. Neurosci. 2025, 9(3), 34; https://doi.org/10.3390/ctn9030034 - 4 Aug 2025
Viewed by 1365
Abstract
Dementia prevention is a global public health priority, and lifestyle interventions, including nutrition, have gained interest for their potential to maintain cognitive health. Among nutritional interventions, omega-3 polyunsaturated fatty acids (n-3 FA), particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been widely [...] Read more.
Dementia prevention is a global public health priority, and lifestyle interventions, including nutrition, have gained interest for their potential to maintain cognitive health. Among nutritional interventions, omega-3 polyunsaturated fatty acids (n-3 FA), particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been widely studied for their potential to support cognitive health. This systematic review evaluated whether n-3 FA supplementation improves global cognition in cognitively unimpaired older adults. Nineteen randomized controlled trials (RCTs) met inclusion criteria, of which five reported significant improvements in global cognition. A random-effects meta-analysis of 11 placebo-controlled RCTs showed no significant effect (SMD = −0.02, 95% CI: −0.07 to 0.04). Heterogeneity in supplement type, dosage, duration, and outcome measures may have contributed to inconsistent findings and limited comparability. Furthermore, methodological quality of the trials was generally low. While current evidence does not demonstrate a significant effect of n-3 FA supplementation on global cognition, future research should prioritize well-powered, longer-duration RCTs that incorporate biomarker monitoring and more appropriate doses. Clarifying the role of n-3 FA in cognitive aging remains essential for informing nutrition-based dementia prevention strategies. Full article
(This article belongs to the Special Issue Brain Health)
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15 pages, 606 KiB  
Article
Assessment of the Physical and Emotional Health-Related Quality of Life Among Congestive Heart Failure Patients with Preserved and Reduced Ejection Fraction at a Quaternary Care Teaching Hospital in Coastal Karnataka in India
by Rajesh Kamath, Vineetha Poojary, Nishanth Shekar, Kanhai Lalani, Tarushree Bari, Prajwal Salins, Gwendolen Rodrigues, Devesh Teotia and Sanjay Kini
Healthcare 2025, 13(15), 1874; https://doi.org/10.3390/healthcare13151874 - 31 Jul 2025
Viewed by 349
Abstract
Introduction: Congestive heart failure (CHF), a complex clinical syndrome characterized by the heart’s inability to pump blood effectively due to structural or functional impairments, is a growing public health concern, with profound implications for patients’ physical and emotional well-being. In India, the burden [...] Read more.
Introduction: Congestive heart failure (CHF), a complex clinical syndrome characterized by the heart’s inability to pump blood effectively due to structural or functional impairments, is a growing public health concern, with profound implications for patients’ physical and emotional well-being. In India, the burden of CHF is rising due to aging demographics and increasing prevalence of lifestyle-related risk factors. Among the subtypes of CHF, heart failure with preserved ejection fraction (HFpEF), i.e., heart failure with left ventricular ejection fraction of ≥50% with evidence of spontaneous or provokable increased left ventricular filling pressure, and heart failure with reduced ejection fraction (HFrEF), i.e., heart failure with left ventricular ejection fraction of 40% or less and is accompanied by progressive left ventricular dilatation and adverse cardiac remodeling, may present differing impacts on health-related quality of life (HRQoL), i.e., an individual’s or a group’s perceived physical and mental health over time, yet comparative data remains limited. This study assesses HRQoL among CHF patients using the Minnesota Living with Heart Failure Questionnaire (MLHFQ), one of the most widely used health-related quality of life questionnaires for patients with heart failure based on physical and emotional dimensions and identifies sociodemographic and clinical variables influencing these outcomes. Methods: A cross-sectional analytical study was conducted among 233 CHF patients receiving inpatient and outpatient care at the Department of Cardiology at a quaternary care teaching hospital in coastal Karnataka in India. Participants were enrolled using convenience sampling. HRQoL was evaluated through the MLHFQ, while sociodemographic and clinical characteristics were recorded via a structured proforma. Statistical analyses included descriptive measures, independent t-test, Spearman’s correlation and stepwise multivariable linear regression to identify associations and predictors. Results: The mean HRQoL score was 56.5 ± 6.05, reflecting a moderate to high symptom burden. Patients with HFpEF reported significantly worse HRQoL (mean score: 61.4 ± 3.94) than those with HFrEF (52.9 ± 4.64; p < 0.001, Cohen’s d = 1.95). A significant positive correlation was observed between HRQoL scores and age (r = 0.428; p < 0.001), indicating that older individuals experienced a higher burden of symptoms. HRQoL also varied significantly across NYHA functional classes (χ2 = 69.9, p < 0.001, ε2 = 0.301) and employment groups (χ2 = 17.0, p < 0.001), with further differences noted by education level, gender and marital status (p < 0.05). Multivariable linear regression identified age (B = 0.311, p < 0.001) and gender (B = –4.591, p < 0.001) as significant predictors of poorer HRQoL. Discussion: The findings indicate that patients with HFpEF experience significantly poorer HRQoL than those with HFrEF. Older adults and female patients reported greater symptom burden, underscoring the importance of demographic-sensitive care approaches. These results highlight the need for routine integration of HRQoL assessment into clinical practice and the development of comprehensive, personalized interventions addressing both physical and emotional health dimensions, especially for vulnerable subgroups. Conclusions: CHF patients, especially those with HFpEF, face reduced HRQoL. Key factors include age, gender, education, employment, marital status, and NYHA class, underscoring the need for patient-centered care. Full article
(This article belongs to the Special Issue Patient Experience and the Quality of Health Care)
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30 pages, 3348 KiB  
Review
Augmented Reality and Virtual Reality in Exergaming
by Georgios Lampropoulos, Theofylaktos Anastasiadis and Juan Garzón
Future Internet 2025, 17(8), 332; https://doi.org/10.3390/fi17080332 - 25 Jul 2025
Cited by 1 | Viewed by 633
Abstract
This study presents a systematic review regarding the use of augmented reality and virtual reality in exergaming by analyzing studies published during 2010–2025. This study focuses on providing an overview of the field and on examining and synthesizing the findings of related studies [...] Read more.
This study presents a systematic review regarding the use of augmented reality and virtual reality in exergaming by analyzing studies published during 2010–2025. This study focuses on providing an overview of the field and on examining and synthesizing the findings of related studies to identify the contexts, applications, and domains in which extended reality exergames are being used and the related implications, benefits, and challenges. Based on the results, augmented reality and virtual reality exergames offer immersive, enjoyable, engaging, and personalized experiences that support physical, cognitive, and emotional well-being, while enhancing physical performance, cognitive functioning, psychological outcomes, and mental health. They promote motivation, active lifestyles, and sustainable health behaviors across diverse populations, including older adults, individuals with disabilities, and neurological groups, as well as the general adult and youth populations. Although emphasis is placed on their use in physical and cognitive rehabilitation and treatment, they also show great potential to be effectively used in different domains, including education. Among the technologies examined, the significant majority of studies focused on virtual reality exergames, a limited number of studies involved augmented reality, and only a few studies examined mixed reality, extended reality, and the metaverse. Finally, nine main topics were identified through topic modeling, providing a clear representation of the core themes within the literature. Full article
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37 pages, 1234 KiB  
Review
The Complex Gene–Carbohydrate Interaction in Type 2 Diabetes: Between Current Knowledge and Future Perspectives
by Francesca Gorini and Alessandro Tonacci
Nutrients 2025, 17(14), 2350; https://doi.org/10.3390/nu17142350 - 17 Jul 2025
Viewed by 664
Abstract
Type 2 diabetes (T2D) represents a public health problem globally, with the highest prevalence reported among older adults. While an interplay of various determinants including genetic, epigenetic, environmental factors and unhealthy lifestyle, particularly diet, has been established to contribute to T2D development, emerging [...] Read more.
Type 2 diabetes (T2D) represents a public health problem globally, with the highest prevalence reported among older adults. While an interplay of various determinants including genetic, epigenetic, environmental factors and unhealthy lifestyle, particularly diet, has been established to contribute to T2D development, emerging evidence supports the role of interactions between nutrients or dietary patterns and genes in the pathogenesis of this metabolic disorder. The amount, and especially the type of carbohydrates, in particular, have been correlated with the risk of non-communicable chronic disease and mortality. This narrative review aims to discuss the updated data on the complex and not fully elucidated relationship between carbohydrate–gene interactions and incidence of T2D, identifying the most susceptible genes able to modulate the dual association between carbohydrate intake and risk of developing T2D. The identification of genetic polymorphisms in response to this macronutrient represents a potentially powerful target to estimate individual risk and prevent the development of T2D in the context of personalized medicine. The postulation around novel foods potentially tailored to minimize the risks of developing T2D will pave the way for a new era into food research in relation to the safeguarding of well-being status in patients affected by, or at risk for, T2D. Full article
(This article belongs to the Special Issue Advances in Gene–Diet Interactions and Human Health)
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31 pages, 799 KiB  
Article
Exploring Determinants of Mediterranean Lifestyle Adherence: Findings from the Multinational MEDIET4ALL e-Survey Across Ten Mediterranean and Neighboring Countries
by Achraf Ammar, Mohamed Ali Boujelbane, Atef Salem, Khaled Trabelsi, Bassem Bouaziz, Mohamed Kerkeni, Liwa Masmoudi, Juliane Heydenreich, Christiana Schallhorn, Gabriel Müller, Ayse Merve Uyar, Hadeel Ali Ghazzawi, Adam Tawfiq Amawi, Bekir Erhan Orhan, Giuseppe Grosso, Osama Abdelkarim, Mohamed Aly, Tarak Driss, Kais El Abed, Wassim Moalla, Piotr Zmijewski, Frédéric Debeaufort, Nasreddine Benbettaieb, Clément Poulain, Laura Reyes, Amparo Gamero, Marta Cuenca-Ortolá, Antonio Cilla, Nicola Francesca, Concetta Maria Messina, Enrico Viola, Björn Lorenzen, Stefania Filice, Aadil Bajoub, El-Mehdi Ajal, El Amine Ajal, Majdouline Obtel, Sadjia Lahiani, Taha Khaldi, Nafaa Souissi, Omar Boukhris, Waqar Husain, Evelyn Frias-Toral, Walid Mahdi, Hamdi Chtourou, Haitham Jahrami and Wolfgang I. Schöllhornadd Show full author list remove Hide full author list
Nutrients 2025, 17(14), 2280; https://doi.org/10.3390/nu17142280 - 10 Jul 2025
Viewed by 802
Abstract
Background/Objectives: Despite its well-established health benefits, adherence to the Mediterranean lifestyle (MedLife) has declined globally, including in its region of origin, alongside a significant shift toward ultra-processed food consumption. Understanding the factors associated with MedLife adherence is essential for developing targeted interventions and [...] Read more.
Background/Objectives: Despite its well-established health benefits, adherence to the Mediterranean lifestyle (MedLife) has declined globally, including in its region of origin, alongside a significant shift toward ultra-processed food consumption. Understanding the factors associated with MedLife adherence is essential for developing targeted interventions and tailored policy recommendations. As part of the MEDIET4ALL PRIMA project, this cross-sectional study aimed to comprehensively examine geo-demographic, socio-economic, psychological, behavioral, and barrier-related factors associated with and potentially contributing to MedLife adherence. Methods: Data were collected from 4010 participants aged 18 years and above across ten Mediterranean and neighboring countries using the multinational MEDIET4ALL e-survey, which included the validated MedLife index, along with various other questionnaires. Results: Results indicate that only 22% of respondents demonstrated high adherence to the Mediterranean lifestyle (MedLife), with significant variability observed across countries, age groups, education levels, and health statuses. Spain had the highest proportion of participants with high adherence (38%). Factors associated with significantly higher adherence rates include older age, living in the Mediterranean region, higher education levels, a greater awareness of MedLife principles, lower perceived barriers, normal BMI, better health status, and stable economic and marital conditions (p-values ranging from 0.04 to <0.001). Additionally, individuals with high MedLife adherence exhibited more socially and physically active lifestyles and experienced less psychological strain (p < 0.001). Regression analyses identified MedLife awareness as the strongest positive predictor of adherence (β = 0.206), followed by social participation (β = 0.194) and physical activity (β = 0.096). Additional positive contributors include life satisfaction, sleep quality, living in the Mediterranean region, age, and education (β ranging from 0.049 to 0.093). Conversely, factors that are negatively associated with adherence include sedentary behavior, living environment, and barriers such as low motivation, taste dislike, price unaffordability, limited availability, and the time-consuming nature of preparing Mediterranean food (MedFood; β ranging from −0.036 to −0.067). Conclusions: These findings indicate that fewer than one in four adults across Mediterranean and neighboring countries demonstrate high adherence to MedLife, supporting prior evidence of suboptimal adherence even within Mediterranean regions. This study identified a range of behavioral, socio-demographic, and environmental factors—both positive and negative predictors—that can help guide the design of targeted, culturally adapted interventions to promote MedLife behavior. Future research should incorporate objective measurements and longitudinal monitoring to better understand underlying mechanisms, establish causality, and develop sustainable strategies for enhancing MedLife adherence in diverse populations. Full article
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15 pages, 439 KiB  
Article
Influence of Sociodemographic Variables on the Lifestyle of the Adult Population: A Multicenter Observational Study
by David García-García, Francisco Javier Pérez-Rivas, Tomás Gómez-Gascón, Ponte a 100 Clinical Investigators Group , Milagros Rico Blázquez, Marianela Bayón Cabeza, Susana Belmonte Cortés, Julia Domínguez-Bidagor and Jennifer Jiménez-González
Healthcare 2025, 13(13), 1564; https://doi.org/10.3390/healthcare13131564 - 30 Jun 2025
Viewed by 359
Abstract
Background/Objective: The impact that lifestyle has on someone’s health has been widely proven. And the lifestyle can also be highly influenced by the sociodemographic background; however, there is less literature that focuses on this matter. Hence, the objective of the present study is [...] Read more.
Background/Objective: The impact that lifestyle has on someone’s health has been widely proven. And the lifestyle can also be highly influenced by the sociodemographic background; however, there is less literature that focuses on this matter. Hence, the objective of the present study is to analyze the influence of sociodemographic variables on the lifestyle of the adult population. Methods: A cross-sectional multicenter study was conducted in 20 health centers of the Community of Madrid (Spain). A total of 365 participants were scheduled for nursing consultations and recruited through systematic probabilistic sampling. Lifestyle was assessed using the “Ponte a 100” questionnaire; based on the total score achieved by the participants, these were categorized into four groups depending on their need to adopt healthier lifestyle habits: minimal need (80–100 points), mild need (60–79 points), moderate need (40–59 points), and high need (<39 points). Results: Values ranged from 23 to 98 points in the Lifestyle Index (ISEV), with an average of 71.8 (SD = 14.6 points). Older individuals had better eating habits (β = −1.982), while younger individuals had better physical activity habits and a higher consumption of toxic substances. Men consumed more alcohol (β = −2.307) and felt happier with their lives, while women took more active breaks. Being a student was associated with higher levels of stress and anxiety, lower physical activity and leisure time, and higher alcohol consumption. Retirees had better emotional well-being indices (β = 0.999). Lower income levels were associated with occasional drug use and poorer emotional well-being. People with university degrees had better emotional states (β = 0.861) and better eating habits (β = 1.652) and engaged in more intense physical activity. Having no chronic diseases was related to being more physically active (β = 1.789). Conclusions: The study population generally presents a healthy lifestyle. The dimension of emotional well-being was the most influenced by sociodemographic factors. This study contributes to understanding the impact of socioeconomic variables on lifestyle. Full article
(This article belongs to the Special Issue Preventive Care in Healthcare—2nd Edition)
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32 pages, 392 KiB  
Article
Chronic Illnesses: Varied Health Patterns and Mental Health Challenges
by Ângela Leite
Healthcare 2025, 13(12), 1396; https://doi.org/10.3390/healthcare13121396 - 11 Jun 2025
Viewed by 1838
Abstract
Background/Objectives: Hypertension, diabetes, and cancer are three prevalent chronic conditions with distinct etiologies and significant global health impacts. This study aimed to explore the diverse impacts of different chronic illnesses on health behaviors and psychological well-being, with a focus on identifying and addressing [...] Read more.
Background/Objectives: Hypertension, diabetes, and cancer are three prevalent chronic conditions with distinct etiologies and significant global health impacts. This study aimed to explore the diverse impacts of different chronic illnesses on health behaviors and psychological well-being, with a focus on identifying and addressing the unique challenges faced by individuals with hypertension, diabetes, and cancer. It was hypothesized that health behaviors and psychological well-being would differ significantly among individuals with hypertension, diabetes, and cancer, reflecting the distinct demands and psychosocial impacts of each condition. Methods: The database of Americans’ Changing Lives, Wave 6, including 767 participants, was used (56.1% hypertension, 20.8% diabetes, and 19.9% cancer cases). Variables concerning physical and mental health issues were chosen. Descriptive statistics summarized the data. Chi-squared and t-tests assessed associations and group differences, with effect sizes reported. Logistic regression examined predictors of hypertension, diabetes, and cancer. Sensitivity analyses excluded outliers. Results: Hypertensive individuals are more likely to show cognitive impairment and unhealthy behaviors, including poor self-rated health, higher BMI, lower physical activity, and altered alcohol use. Risk increases with age, widowhood, retirement, hospital admissions, and poor mental health, while more emergency room or doctor visits slightly reduce it. People with diabetes experience greater depressive symptoms, hopelessness, and financial stress. They also tend to have poorer self-rated health, higher BMI, and less physical activity. Risk is higher for separated individuals and lower for females. Psychological distress is a key factor, while age, employment, and healthcare use show minimal influence. Cancer is linked to chronic stress, poorer perceived health, and mental health challenges. Risk is higher among older adults and those who keep house. Poor self-rated health, high BMI, low fruit and vegetable intake, and psychological distress increase risk, but healthcare use is not a strong predictor. Conclusions: While different chronic illnesses present distinct challenges to health behaviors and psychological well-being, they also share common features-such as increased stress and lifestyle disruptions-underscoring the importance of both tailored and cross-cutting interventions to effectively support individuals across conditions. Full article
20 pages, 1078 KiB  
Article
Atherogenic Risk and Its Association with Alcohol Consumption, Lifestyle Habits, and Sociodemographic Factors in a Population of Spanish Workers
by Joan Obrador de Hevia, Ángel Arturo López-González, José Ignacio Ramírez-Manent, Carla Busquets-Cortes, Pedro Juan Tárraga López, Miguel García Samuelsson and Pere Riutord-Sbert
Life 2025, 15(6), 923; https://doi.org/10.3390/life15060923 - 7 Jun 2025
Viewed by 505
Abstract
Atherogenic dyslipidemia is a major contributor to cardiovascular disease, the leading cause of morbidity and mortality worldwide. While lipid abnormalities are well-established clinical risk factors, growing evidence highlights the influence of sociodemographic and lifestyle determinants on lipid profiles. However, large-scale epidemiological data addressing [...] Read more.
Atherogenic dyslipidemia is a major contributor to cardiovascular disease, the leading cause of morbidity and mortality worldwide. While lipid abnormalities are well-established clinical risk factors, growing evidence highlights the influence of sociodemographic and lifestyle determinants on lipid profiles. However, large-scale epidemiological data addressing these associations within occupational settings remain limited. Objective: To assess the cross-sectional and longitudinal associations between atherogenic risk—measured through TC/HDL-c, LDL-c/HDL-c, TG/HDL-c ratios, and atherogenic dyslipidemia (AD)—and sociodemographic variables, health behaviors, and alcohol consumption in a large cohort of Spanish workers. Methods: A dual-phase study was conducted. The first phase was a cross-sectional analysis of 139,634 workers (83,282 men; 56,352 women) from multiple employment sectors undergoing routine occupational health assessments. The second phase was a longitudinal study of a subsample (n = 40,431) with complete data from 2009 and 2019. Clinical, anthropometric, and biochemical data were collected using standardized protocols. Lifestyle factors (smoking, physical activity, Mediterranean diet adherence, alcohol intake) and socioeconomic indicators (education, occupational class) were recorded. Multinomial logistic regression was used to determine independent associations with high-risk atherogenic profiles. Results: Higher atherogenic indices and prevalence of AD were associated with advancing age, lower educational level, lower social class, smoking, physical inactivity, poor diet quality, and alcohol consumption. Men exhibited higher TG/HDL-c and AD values, whereas women had higher TC/HDL-c and LDL-c/HDL-c. Physical inactivity showed the strongest association with TG/HDL-c (OR: 36.23; 95% CI: 32.12–40.35) and AD (OR: 16.86; 95% CI: 14.80–18.93). Alcohol intake also independently predicted higher TG/HDL-c (OR: 1.60) and AD (OR: 1.79). Over the decade, a general increase in atherogenic risk was observed, especially among older adults, socially disadvantaged groups, and those with unhealthy behaviors. Conclusions: Sociodemographic and lifestyle factors, particularly physical inactivity and alcohol consumption, are strongly associated with adverse atherogenic profiles in the working population. The observed rise in lipid-related cardiovascular risk over the past decade emphasizes the urgent need for workplace-based health promotion strategies targeting modifiable behaviors and structural health inequalities. Full article
(This article belongs to the Section Physiology and Pathology)
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39 pages, 7831 KiB  
Article
Psychosocial Factors, Stress, and Well-Being: Associations with Common Dermatological Manifestations in a Large Polish Cross-Sectional Analysis
by Anna Kubrak, Anna Zimny-Zając, Sebastian Makuch, Beata Jankowska-Polańska, Wojciech Tański, Jacek C. Szepietowski and Siddarth Agrawal
J. Clin. Med. 2025, 14(11), 3943; https://doi.org/10.3390/jcm14113943 - 3 Jun 2025
Viewed by 465
Abstract
Background/Objectives: Cutaneous manifestations can signal underlying systemic inflammation, potentially exacerbated by chronic stress and diminished well-being. While links between psychosocial factors and skin health are recognized, comprehensive data across diverse populations remain limited. This study aimed to quantify associations between self-reported stress management [...] Read more.
Background/Objectives: Cutaneous manifestations can signal underlying systemic inflammation, potentially exacerbated by chronic stress and diminished well-being. While links between psychosocial factors and skin health are recognized, comprehensive data across diverse populations remain limited. This study aimed to quantify associations between self-reported stress management capabilities, sociodemographic factors (gender, age, education, urbanization, professional status), lifestyle factors indicative of well-being, and the prevalence of six common dermatological manifestations (pruritus, burning sensations, redness, rash, desquamation, sunburn) within a large Polish cohort. Methods: This cross-sectional study analyzed data from 27,000 adult participants (22,043 women, 4887 men) collected during the National Healthy Skin Test (2023) via an online questionnaire. Participants reported the frequency of dermatological symptoms, stress management practices related to skin health, and relevant lifestyle factors (indicators of well-being). Logistic regression analyses identified significant predictors for each skin manifestation. Results: Effective stress coping ability was significantly associated with a lower prevalence of all six investigated dermatological manifestations (p < 0.001 for all). Significant gender differences emerged: women reported more frequent redness and burning sensations (p < 0.001), while men reported more frequent rash, sunburn, and desquamation (p < 0.001). Younger age (18–24 years) was associated with increased rash, desquamation, and redness compared to older adults (>65 years), who reported fewer burning sensations and less pruritus. Higher education and residence in large urban centers (≥500,000 inhabitants) were associated with increased reports of specific symptoms like sunburn and redness. Conclusions: This large-scale study demonstrates a significant association between psychosocial factors, particularly self-reported stress management, and the prevalence of six common, self-reported dermatological manifestations across various sociodemographic groups in Poland. The findings underscore the potential importance of considering a biopsychosocial approach in relation to these common skin symptoms. Further research is warranted, but these results suggest that for such common, self-reported skin issues, integrating stress reduction strategies and considering sociodemographic contexts and well-being may be valuable considerations for potentially enhancing personalized patient care and warrant further clinical investigation. Full article
(This article belongs to the Special Issue Clinical Epidemiology of Skin Diseases: 3rd Edition)
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13 pages, 668 KiB  
Review
Comprehensive Strategies for Preventive Periodontal Care in Older Adults
by Alice Kit Ying Chan, Yiu-Cheung Tsang, Stephanie Chu and Chun-Hung Chu
Geriatrics 2025, 10(3), 72; https://doi.org/10.3390/geriatrics10030072 - 25 May 2025
Cited by 1 | Viewed by 789
Abstract
Background: Periodontal health is closely related to systemic health and crucial for healthy aging. Periodontal disease is prevalent among older adults due to declined systemic conditions, medication side effects, and reduced dexterity and cognition. Effective preventive care is essential to maintain periodontal health [...] Read more.
Background: Periodontal health is closely related to systemic health and crucial for healthy aging. Periodontal disease is prevalent among older adults due to declined systemic conditions, medication side effects, and reduced dexterity and cognition. Effective preventive care is essential to maintain periodontal health and promote oral and general health. Objective: The aim of this narrative review is to examine preventive periodontal care tailored for older individuals, with a focus on strategies to reduce the incidence of periodontal disease, maintain periodontal health, and improve the overall well-being of older adults. Findings: Preventive periodontal care includes mechanical plaque control, use of chemotherapeutic agents, lifestyle modifications, and regular professional periodontal care. Mechanical plaque control through regular toothbrushing and interdental cleaning remains the cornerstone of prevention. The use of adaptive aids and caregiver support is essential for maintaining the oral hygiene of older adults with physical limitations. Chemotherapeutic agents, such as chlorhexidine mouth rinses, can be used as adjunctive agents for plaque control. Lifestyle modifications, like smoking cessation and dietary adjustments, are crucial components of risk factor control. Professional periodontal care, including periodontal evaluation, risk factor control, tailored oral hygiene instruction, and professional mechanical plaque removal, are essential for the prevention and early detection and management of periodontal disease in older adults. Conclusions: This review underscores the importance of a multidisciplinary approach involving oral healthcare professionals, primary care providers, and caregivers to ensure patient-centered, integrated and comprehensive geriatric care to improve periodontal outcomes and overall well-being of older adults. Full article
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19 pages, 9097 KiB  
Article
Metabolic Markers Demonstrate the Heterogeneity of Walking Ability in Non-Disabled Community-Dwelling Older Adults
by Shanshan Yao, Ziling Mao, Megan M. Marron, Eleanor M. Simonsick, Venkatesh L. Murthy, Ravi V. Shah and Anne B. Newman
Metabolites 2025, 15(5), 334; https://doi.org/10.3390/metabo15050334 - 19 May 2025
Viewed by 604
Abstract
Background: Walking ability is important for the quality of life of older adults. A self-reported walking ability index (WAI) covering the difficulty and ease of walking captures a broader spectrum of walking ability in healthy older persons. Methods: Using metabolomics in [...] Read more.
Background: Walking ability is important for the quality of life of older adults. A self-reported walking ability index (WAI) covering the difficulty and ease of walking captures a broader spectrum of walking ability in healthy older persons. Methods: Using metabolomics in the Health, Aging and Body Composition study, we identified Year 2 metabolites cross-sectionally and longitudinally related to WAI (0–9, higher scores indicate better walking ability) using probabilistic index models and multinomial logistic models, respectively. Results: Among 2334 participants (mean age 74.6 years, 51% women, 37% Black), 27% scored 0–5, 36% scored 6–8, and 37% scored 9 at Year 2. Over 4 years, 52% maintained a stable WAI, 6% improved, while 42% declined (22% 1–2 points and 20% >2 points decline). We identified 81 metabolites significantly associated with both poorer concurrent WAI and faster decline, including higher acylcarnitine species, shorter-chain saturated diglycerides and triglycerides, and TCA cycle intermediates (cis-aconitic, fumaric, and malic acids), and lower phospholipids levels. Eighteen additional metabolites were only associated with faster WAI decline: higher short-chain saturated triglycerides and energy metabolism markers (ATP/ADP/AMP) and lower margaric acid and glycine levels. Notably, those with improved WAI, despite poorer baseline WAI and lifestyles, showed more favorable metabolic profiles than others. Conclusions: Metabolites linked to the TCA cycle and energy metabolism, as well as inflammation and protein catabolism, were related to mobility function. Some metabolites might be particularly important for the early detection of older adults at risk of mobility decline. Metabolic profiles may also help identify older individuals (i.e., with improving WAI) with greater metabolic resilience to lifestyle risk factors and health conditions. Full article
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24 pages, 3495 KiB  
Review
Dietary Patterns and Brain Health in Middle-Aged and Older Adults: A Narrative Review
by Jamie A. Seabrook, Abolfazl Avan, Colleen O’Connor, Harry Prapavessis, Lindsay Nagamatsu, Jasna Twynstra, Saverio Stranges, Arlene MacDougall and Vladimir Hachinski
Nutrients 2025, 17(9), 1436; https://doi.org/10.3390/nu17091436 - 24 Apr 2025
Cited by 1 | Viewed by 3033
Abstract
Diet has a profound impact on brain health, particularly in middle-aged and older adults, who are at increased risk of cognitive decline and neurodegenerative diseases. Various dietary patterns, including the Mediterranean diet (MedDiet), Dietary Approaches to Stop Hypertension (DASH), and Mediterranean-DASH Intervention for [...] Read more.
Diet has a profound impact on brain health, particularly in middle-aged and older adults, who are at increased risk of cognitive decline and neurodegenerative diseases. Various dietary patterns, including the Mediterranean diet (MedDiet), Dietary Approaches to Stop Hypertension (DASH), and Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diets, have been linked to improved cognitive function. While the relative effectiveness of these diets on brain health is generally supported by evidence, variability in study results suggests that further research is needed to fully understand their effects across diverse populations. The objective of this descriptive narrative review is to examine the role of dietary patterns in supporting brain health in aging populations and to propose practical dietary strategies for promoting cognitive well-being. A comprehensive review of the existing literature was conducted on PubMed in October 2024, with no restrictions on language, publication date (1966–2024), or geographic location. A total of 18 articles were included in this review, covering the years 2013–2023. Studies assessing the impact of the MedDiet, DASH, MIND, and Western diets on cognitive function in middle-aged and older adults were prioritized. The research findings were synthesized to identify common and unique recommendations across these dietary patterns. The MedDiet consistently showed beneficial effects on cognitive health, including improved memory, processing speed, and long-term protection against neurodegenerative conditions. The DASH and MIND diets demonstrated potential benefits, particularly for specific cognitive domains, but the results were more mixed and inconclusive. In contrast, adherence to a Western diet was associated with negative cognitive outcomes, including cognitive decline and smaller brain volumes. These findings underscore the importance of adopting healthy dietary patterns as a modifiable lifestyle factor to support cognitive aging and inform future public health strategies and clinical guidelines. Full article
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15 pages, 526 KiB  
Systematic Review
Meshing Anxiety, Depression, Quality of Life, and Functionality in Chronic Disease
by Ana Pedro Costa, Irma da Silva Brito, Teresa Dionísio Mestre, Ana Matos Pires and Manuel José Lopes
Healthcare 2025, 13(5), 539; https://doi.org/10.3390/healthcare13050539 - 2 Mar 2025
Cited by 3 | Viewed by 1796
Abstract
Background/Objectives: Anxiety and depression result in a greater health burden; both can impact functionality and quality of life. This review aims to understand the association between anxiety, depression, functionality, and quality of life. Although three systematic reviews exist, one focuses on quality of [...] Read more.
Background/Objectives: Anxiety and depression result in a greater health burden; both can impact functionality and quality of life. This review aims to understand the association between anxiety, depression, functionality, and quality of life. Although three systematic reviews exist, one focuses on quality of life in depression and anxiety, while the others address functionality in depression and anxiety, with the former being more recent and the latter two being older. The association between these four variables will be explored. Methods: A literature search of MEDLINE with Full Text, CINHAL PLUS with Full Text, Psychology and Behavioral Sciences Collection, and Academic Search Complete was conducted from 1 January 2017 to 22 November 2022. Seven studies involving 2279 adults were included. Results: All studies analyzed the association between anxiety and/or depression with functionality and/or quality of life, in a population with a primary chronic condition. We found the higher functionality (return to work, no sedentary lifestyle, and no fatigue) and quality of life are, the lower the values of anxiety and depression will be. The HADS is a consensual instrument to access anxiety and depression, but the same cannot be said for assessing functionality and quality of life. Conclusions: The severity of the chronic disease and the loss of functionality and quality of life seem to increase psychological distress. This study highlights the importance of a multidisciplinary and holistic approach, focusing not only on clinical outcomes but also on overall well-being. Further longitudinal research is needed to support the association between these variables to draw more concrete conclusions with scientific evidence. Full article
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27 pages, 9220 KiB  
Article
Dietary Habits and Their Correlation with Socio-Demographic Variables Among the Ethnic Hungarian Population of Romania
by Francisc-Andrei Boda, Béla Kovács, Bernadett Molnar, Boglárka Kovács-Deák and Lavinia Berța
Nutrients 2025, 17(5), 756; https://doi.org/10.3390/nu17050756 - 21 Feb 2025
Cited by 2 | Viewed by 1110
Abstract
Background/Objectives: Non-communicable diseases (NCDs) are the leading cause of preventable morbidity and mortality globally. To reduce the prevalence of NCDs, the World Health Organization issued guidelines for a healthy lifestyle, which have been adopted in various countries. Our study aimed to evaluate [...] Read more.
Background/Objectives: Non-communicable diseases (NCDs) are the leading cause of preventable morbidity and mortality globally. To reduce the prevalence of NCDs, the World Health Organization issued guidelines for a healthy lifestyle, which have been adopted in various countries. Our study aimed to evaluate the dietary habits of the ethnic Hungarian population of Romania, allowing us to identify potential differences in nutritional behavior compared to the country’s general population. Methods: A cross-sectional, observational, questionnaire-based study was conducted to collect information on eating behavior, food purchasing habits, and dietary patterns among ethnic Hungarians, the largest minority group in Romania. The obtained data were interpreted using multivariate data analysis (MVDA), including principal component analysis models (PCA-X) to establish pattern recognition and data clustering, and orthogonal partial least squares discriminant analysis (OPLS-DA) models to examine class differences between the identified clusters. Results: A total of 247 valid questionnaires were evaluated; the most represented groups were females (67.2%), young adults aged 18 to 30 (56.3%), individuals with normal body mass index (54.7%), and those with a higher education level (45.7%). Health-conscious purchasing and eating behaviors were more characteristic of middle-aged and older adults, females, and those with a higher education level. Young adults appear to have a more varied diet, but overconsumption of unhealthy food products and a lack of interest in healthy dietary habits is evident. Conclusions: Appropriate nutritional education is necessary for all age groups; however, programs targeting young adult Hungarians are especially important, as most expressed little interest in healthy eating habits. Further research examining the underlying relationship between dietary habits and cultural factors as well as socio-economic factors could offer new opportunities to promote a healthy lifestyle. Full article
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18 pages, 272 KiB  
Article
Sedentary Behaviour and Its Correlates Among Older Adults in Malaysia
by Chee Cheong Kee, Lay Kim Tan, Yong Kang Cheah, Chien Huey Teh, Hui Li Lim, Yoon Ling Cheong, Mohd Azahadi Omar and Sumarni Mohd Ghazali
Healthcare 2025, 13(2), 160; https://doi.org/10.3390/healthcare13020160 - 15 Jan 2025
Viewed by 1685
Abstract
Background: Sedentary behaviors (SBs), which are low-energy, wakeful activities performed in a sitting, reclining, or lying posture, are independently associated with numerous adverse health outcomes, including mental health disorders, non-communicable diseases, and an increased risk of mortality. This study investigated associations between sociodemographic [...] Read more.
Background: Sedentary behaviors (SBs), which are low-energy, wakeful activities performed in a sitting, reclining, or lying posture, are independently associated with numerous adverse health outcomes, including mental health disorders, non-communicable diseases, and an increased risk of mortality. This study investigated associations between sociodemographic characteristics, lifestyle factors, mental health, nutritional status, social support, functional limitations, and SB among older persons in Malaysia. Methods: Data from 3977 individuals aged 60 years and above, extracted from the National Health and Morbidity Survey (NHMS) 2018, were analyzed using complex samples logistic regression. Results: The prevalence of sedentary behavior, defined as sitting or reclining for 8 or more hours per day, among the surveyed population was 23.2%. Older age (≥75 years) was significantly associated with higher odds of SB (AORs 1.58 to 2.76, p < 0.001 to p = 0.001). Unemployment (AOR = 1.32, p = 0.020) and indigenous Sabah and Sarawak ethnicity (AOR = 2.48, p = 0.007) were also linked to increased odds of SB. Conversely, individuals with a monthly income of MYR 1000-1999 had lower odds of SB compared to those earning ≥MYR 2000 (AOR = 0.64, p = 0.022), and those at risk of malnutrition were also less likely to engage in SB (AOR = 0.68, p = 0.031). No significant associations were found between SB and sex, marital status, educational level, or chronic illness. Conclusions: These findings suggest that public health initiatives to reduce SB among older adults should prioritize the oldest aged, unemployed, and specific ethnic communities, as well as addressing nutritional risk to promote healthier aging among older persons in Malaysia. Full article
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