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Health Promotion and Disease Prevention Strategies for Older Populations to...
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Health Promotion and Disease Prevention Strategies for Older Populations to Ensure Healthy Lifespans

A special issue of Healthcare (ISSN 2227-9032). This special issue belongs to the section "Community Care".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 4079

Special Issue Editors

Prof. Dr. Mario Capunzo

E-Mail Website
Guest Editor
Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, 84081 Salerno, Italy
Interests: preventive medicine; epidemiology; cancer; antibiotic resistance; longevity
Dr. Silvana Mirella Aliberti

E-Mail Website
Guest Editor Assistant
Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, 84081 Baronissi, Italy
Interests: epidemiology; biostatistics; preventive medicine; longevity and healthspan; physical activity; health resilience; chronic disease prevention
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Life expectancy has increased due to declining mortality rates, especially among adults and the older population. However, the rapid aging of the population has led to an increase in all age-related diseases, putting more people at risk of chronic disease and disability. One of the biggest challenges and areas of focus for research is finding ways to maintain vitality, resilience, and acceptable levels of health and functional independence throughout the lifespan. This is important not only for people’s well-being, but also for the financial stability of healthcare systems.

This Special Issue is calling for high-quality original research articles, systematic reviews, meta-analyses, and short papers related to health promotion and disease prevention.

Research topics could include, but are not limited to, preventive medicine in aging in the following areas:

  • Cognitive decline;
  • Diabetes;
  • Hepatitis;
  • Cardiovascular diseases;
  • Cancer;
  • Respiratory diseases;
  • Longevity.

We believe it could be beneficial to create a space for those involved in scientific research on these issues to come together to explore new approaches to promote health and prevent disease in the aging population. We hope this can contribute to the broader goal of improving quality of life and sustaining healthcare systems.

Prof. Dr. Mario Capunzo
Dr. Silvana Mirella Aliberti
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Healthcare is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • healthspan
  • preventive measures
  • cognitive decline
  • diabetes
  • hepatitis
  • cardiovascular diseases
  • cancer
  • respiratory diseases
  • longevity

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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18 pages, 272 KiB  
Article
Sedentary Behaviour and Its Correlates Among Older Adults in Malaysia
by Chee Cheong Kee, Lay Kim Tan, Yong Kang Cheah, Chien Huey Teh, Hui Li Lim, Yoon Ling Cheong, Mohd Azahadi Omar and Sumarni Mohd Ghazali
Healthcare 2025, 13(2), 160; https://doi.org/10.3390/healthcare13020160 - 15 Jan 2025
Viewed by 1241
Abstract
Background: Sedentary behaviors (SBs), which are low-energy, wakeful activities performed in a sitting, reclining, or lying posture, are independently associated with numerous adverse health outcomes, including mental health disorders, non-communicable diseases, and an increased risk of mortality. This study investigated associations between sociodemographic [...] Read more.
Background: Sedentary behaviors (SBs), which are low-energy, wakeful activities performed in a sitting, reclining, or lying posture, are independently associated with numerous adverse health outcomes, including mental health disorders, non-communicable diseases, and an increased risk of mortality. This study investigated associations between sociodemographic characteristics, lifestyle factors, mental health, nutritional status, social support, functional limitations, and SB among older persons in Malaysia. Methods: Data from 3977 individuals aged 60 years and above, extracted from the National Health and Morbidity Survey (NHMS) 2018, were analyzed using complex samples logistic regression. Results: The prevalence of sedentary behavior, defined as sitting or reclining for 8 or more hours per day, among the surveyed population was 23.2%. Older age (≥75 years) was significantly associated with higher odds of SB (AORs 1.58 to 2.76, p < 0.001 to p = 0.001). Unemployment (AOR = 1.32, p = 0.020) and indigenous Sabah and Sarawak ethnicity (AOR = 2.48, p = 0.007) were also linked to increased odds of SB. Conversely, individuals with a monthly income of MYR 1000-1999 had lower odds of SB compared to those earning ≥MYR 2000 (AOR = 0.64, p = 0.022), and those at risk of malnutrition were also less likely to engage in SB (AOR = 0.68, p = 0.031). No significant associations were found between SB and sex, marital status, educational level, or chronic illness. Conclusions: These findings suggest that public health initiatives to reduce SB among older adults should prioritize the oldest aged, unemployed, and specific ethnic communities, as well as addressing nutritional risk to promote healthier aging among older persons in Malaysia. Full article
(This article belongs to the Special Issue Health Promotion and Disease Prevention Strategies for Older Populations to Ensure Healthy Lifespans)

Other

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17 pages, 1718 KiB  
Systematic Review
The Beneficial Effects of Lactobacillus Strains on Gut Microbiome in Alzheimer’s Disease: A Systematic Review
by Michael Quansah, Monique Antoinette David, Ralph Martins, Emad El-Omar, Silvana Mirella Aliberti, Mario Capunzo, Slade O. Jensen and Mourad Tayebi
Healthcare 2025, 13(1), 74; https://doi.org/10.3390/healthcare13010074 - 3 Jan 2025
Cited by 3 | Viewed by 2118
Abstract
Background/Objectives: Growing evidence suggests that the gut–brain axis influences brain function, particularly the role of intestinal microbiota in modulating cognitive processes. Probiotics may alter brain function and behavior by modulating gut microbiota, with implications for neurodegenerative diseases like Alzheimer’s disease (AD). The purpose [...] Read more.
Background/Objectives: Growing evidence suggests that the gut–brain axis influences brain function, particularly the role of intestinal microbiota in modulating cognitive processes. Probiotics may alter brain function and behavior by modulating gut microbiota, with implications for neurodegenerative diseases like Alzheimer’s disease (AD). The purpose of this review is to systematically review the current literature exploring the effects of probiotic supplementation on gut microbiota and cognitive function in AD and mild cognitive impairment (MCI). Methods: A comprehensive literature search was conducted across PubMed/Medline, Embase, and Scopus to identify relevant randomized controlled trials (RCTs) from inception to 20 August 2024. The search focused on comparing outcomes between intervention and control/placebo groups. Data searches, article selection, data extraction, and risk of bias assessment were performed in accordance with Cochrane guidelines. Systematic Review Registration: PROSPERO registration no: CRD42023446796. Results: Data from four RCTs involving 293 Individuals (AD and MCI patients) receiving mainly Lactobacillus and Bifidobacterium strains showed some beneficial effects on cognitive function, altered gut microbiota composition, and positively affected metabolic biomarkers. However, variability in microbiota assessment across studies limits the interpretation of results. The limited number and quality of the existing studies make it difficult to draw definitive conclusions from the data. Additional high-quality research is clearly needed. Conclusions: Probiotics show promise as an adjunctive intervention for cognitive decline, but larger, long-term trials are needed to confirm their efficacy and clinical applicability in neurodegenerative diseases like AD. Full article
(This article belongs to the Special Issue Health Promotion and Disease Prevention Strategies for Older Populations to Ensure Healthy Lifespans)
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