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Review

10 Citations

4,970 Views

26 Pages

Microbiota-Accessible Boron-Containing Compounds in Complex Regional Pain Syndrome

Cristina Elena Biţă,
Ion Romulus Scorei,
Ananu Florentin Vreju,
Anca Emanuela Muşetescu,
George Dan Mogoşanu,
Andrei Biţă,
Venera Cristina Dinescu,
Ştefan Cristian Dinescu,
Cristina Criveanu and
Paulina Lucia Ciurea
+ 2 authors

Medicina2023, 59(11), 1965;https://doi.org/10.3390/medicina59111965

7 November 2023

The microbiota–gut–brain axis has garnered increasing attention in recent years for its role in various health conditions, including neuroinflammatory disorders like complex regional pain syndrome (CRPS). CRPS is a debilitating condition...

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Review

9 Citations

4,975 Views

20 Pages

Exploring the Gut Microbiota–Muscle Axis in Duchenne Muscular Dystrophy

Debora Mostosi,
Monica Molinaro,
Sabrina Saccone,
Yvan Torrente,
Chiara Villa and
Andrea Farini

Int. J. Mol. Sci.2024, 25(11), 5589;https://doi.org/10.3390/ijms25115589

21 May 2024

The gut microbiota plays a pivotal role in maintaining the dynamic balance of intestinal epithelial and immune cells, crucial for overall organ homeostasis. Dysfunctions in these intricate relationships can lead to inflammation and contribute to the...

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Review

23 Citations

5,907 Views

20 Pages

Oral–Gut Microbiota, Periodontal Diseases, and Arthritis: Literature Overview on the Role of Probiotics

Martina Ferrillo,
Amerigo Giudice,
Mario Migliario,
Filippo Renó,
Lorenzo Lippi,
Dario Calafiore,
Nicola Marotta,
Roberto de Sire,
Leonzio Fortunato and
Alessandro de Sire
+ 2 authors

Int. J. Mol. Sci.2023, 24(5), 4626;https://doi.org/10.3390/ijms24054626

27 February 2023

Periodontal diseases are oral inflammatory diseases affecting the tissues supporting and surrounding the teeth and include gingivitis and periodontitis. Oral pathogens may lead to microbial products spreading into the systemic circulation and reachin...

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Review

532 Views

17 Pages

Gut and Joint Microbiome and Dysbiosis: A New Perspective on the Pathogenesis and Treatment of Osteoarthritis

Paulina Plewa,
Patryk Graczyk,
Karolina Figiel,
Aleksandra Dach and
Andrzej Pawlik

Pathogens2026, 15(1), 62;https://doi.org/10.3390/pathogens15010062

7 January 2026

Osteoarthritis (OA) is one of the most common and burdensome musculoskeletal disorders and a major cause of pain, disability, and reduced quality of life worldwide. In recent years, increasing attention has been paid to extra-articular factors influe...

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Article

1 Citations

1,025 Views

20 Pages

Comparative Pain Expression and Its Association to Intestinal Microbiota Through the MI-RAT© Osteoarthritis Model Induced in LOU/C/Jall and Sprague-Dawley Aged Rats

Marilyn Frézier,
Colombe Otis,
Emilie Labelle,
Bertrand Lussier,
Pierrette Gaudreau,
Simon Authier,
Marcio Carvalho Costa,
Hélène Beaudry and
Eric Troncy

Int. J. Mol. Sci.2025, 26(16), 7698;https://doi.org/10.3390/ijms26167698

8 August 2025

To investigate the involvement of gut–brain axis in musculoskeletal chronic pain in the elderly, this preclinical study aimed to compare osteoarthritis (OA) pain expression, cognitive function and gut microbiota composition in two aging rat str...

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