- Article
Soft Biomimetic Approach for the Development of Calcinosis-Resistant Glutaraldehyde-Fixed Biomaterials for Cardiovascular Surgery
- Alyona I. Zvyagina,
- Vladislav V. Minaychev,
- Margarita I. Kobyakova,
- Yana V. Lomovskaya,
- Anatoliy S. Senotov,
- Kira V. Pyatina,
- Vladimir S. Akatov,
- Roman S. Fadeev and
- Irina S. Fadeeva
Pathological aseptic calcification is the most common form of structural valvular degeneration (SVD), leading to premature failure of heart valve bioprostheses (BHVs). The processing methods used to obtain GA-fixed pericardium-based biomaterials dete...