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314 Results Found

  • Review
  • Open Access
1 Citations
3,003 Views
12 Pages

17 October 2025

The rapid emergence of antibiotic-resistant bacteria requires solutions that extend beyond conventional antibiotics. Bacteriophages (phages) provide targeted antibacterial action but face two key limitations: (1) their narrow natural host ranges and...

  • Article
  • Open Access
1,078 Views
17 Pages

Navigating the Fitness Landscape: Host Density, Epistasis, and Clonal Interference Drive Divergent Evolutionary Pathways in Phage Qβ

  • Mara Laguna-Castro,
  • Pilar Somovilla,
  • Víctor López-Muñoz,
  • Luis F. Pacios and
  • Ester Lázaro

16 September 2025

Understanding how ecological factors shape viral evolution is essential for predicting adaptation in RNA viruses. In this study, we investigated the evolutionary dynamics of bacteriophage Qβ under varying host densities, focusing on two nonsynon...

  • Article
  • Open Access
774 Views
22 Pages

Synergistic Biocontrol of Agrobacterium tumefaciens by Phage PAT1 and Ascaphin-8: Enhanced Antimicrobial Activity and Virulence Attenuation via HupB Loss

  • Miloud Sabri,
  • Kaoutar El Handi,
  • Cosima Damiana Calvano,
  • Mariachiara Bianco,
  • Angelo De Stradis and
  • Toufic Elbeaino

25 September 2025

Agrobacterium tumefaciens (A. tumefaciens), the causal agent of crown gall disease on several plant species, is responsible for substantial yield losses worldwide. The limitations of conventional pesticides in controlling this disease highlight the n...

  • Article
  • Open Access
9 Citations
3,963 Views
17 Pages

Within-Generation Polygenic Selection Shapes Fitness-Related Traits across Environments in Juvenile Sea Bream

  • Carine Rey,
  • Audrey Darnaude,
  • Franck Ferraton,
  • Bruno Guinand,
  • François Bonhomme,
  • Nicolas Bierne and
  • Pierre-Alexandre Gagnaire

7 April 2020

Understanding the genetic underpinnings of fitness trade-offs across spatially variable environments remains a major challenge in evolutionary biology. In Mediterranean gilthead sea bream, first-year juveniles use various marine and brackish lagoon n...

  • Review
  • Open Access
11 Citations
9,683 Views
33 Pages

Metabolism at Evolutionary Optimal States

  • Iraes Rabbers,
  • Johan H. Van Heerden,
  • Niclas Nordholt,
  • Herwig Bachmann,
  • Bas Teusink and
  • Frank J. Bruggeman

2 June 2015

Metabolism is generally required for cellular maintenance and for the generation of offspring under conditions that support growth. The rates, yields (efficiencies), adaptation time and robustness of metabolism are therefore key determinants of cellu...

  • Article
  • Open Access
270 Views
12 Pages

27 December 2025

Although fitness-related traits are expected to be under strong selection, traits related to reproduction are often quite variable within plant populations. We used data from two large greenhouse experiments to quantify phenotypic, genetic, and envir...

  • Review
  • Open Access
3 Citations
2,517 Views
24 Pages

Biocontrol of Phage Resistance in Pseudomonas Infections: Insights into Directed Breaking of Spontaneous Evolutionary Selection in Phage Therapy

  • Jumpei Fujiki,
  • Daigo Yokoyama,
  • Haruka Yamamoto,
  • Nana Kimura,
  • Manaho Shimizu,
  • Hinatsu Kobayashi,
  • Keisuke Nakamura and
  • Hidetomo Iwano

4 August 2025

Phage therapy, long overshadowed by antibiotics in Western medicine, has a well-established history in some Eastern European countries and is now being revitalized as a promising strategy against antimicrobial resistance (AMR). This resurgence of pha...

  • Review
  • Open Access
43 Citations
7,393 Views
24 Pages

26 October 2023

In recent decades, phage therapy has been overshadowed by the widespread use of antibiotics in Western countries. However, it has been revitalized as a powerful approach due to the increasing prevalence of antimicrobial-resistant bacteria. Although b...

  • Article
  • Open Access
15 Citations
4,851 Views
12 Pages

Positive Correlation between Pesticide Consumption and Longevity in Solitary Bees: Are We Overlooking Fitness Trade-Offs?

  • Verena Strobl,
  • Domenic Camenzind,
  • Angela Minnameyer,
  • Stephanie Walker,
  • Michael Eyer,
  • Peter Neumann and
  • Lars Straub

20 November 2020

The ubiquitous use of pesticides is one major driver for the current loss of biodiversity, and the common practice of simultaneously applying multiple agrochemicals may further contribute. Insect toxicology currently has a strong focus on survival to...

  • Article
  • Open Access
678 Views
12 Pages

9 October 2025

The widespread use of neonicotinoid insecticides has led to increasing resistance in non-target organisms, including the egg parasitoid Trichogramma dendrolimi, a crucial biological control agent. Film-residue bioassays on 17 geographic strains revea...

  • Article
  • Open Access
4 Citations
3,292 Views
10 Pages

Antibiotic resistance is a growing concern that has prompted a renewed focus on drug discovery, stewardship, and evolutionary studies of the patterns and processes that underlie this phenomenon. A resistant strain’s competitive fitness relative...

  • Article
  • Open Access
1 Citations
1,429 Views
14 Pages

Phenotypic Impact and Multivariable Assessment of Antifungal Susceptibility in Candida auris Survival Using a Galleria mellonella Model

  • Jorge Alvarruiz,
  • Alba Cecilia Ruiz-Gaitán,
  • Marta Dafne Cabanero-Navalon,
  • Javier Pemán,
  • Rosa Blanes-Hernández,
  • Santiago de Cossio and
  • Victor Garcia-Bustos

24 May 2025

The novel pathogen Candida auris has rapidly become a major health threat due to its high virulence, resistance to multiple antifungal agents, and remarkable environmental persistence. This study evaluated the influence of phenotypic traits and antif...

  • Article
  • Open Access
1 Citations
1,482 Views
10 Pages

2 November 2024

Natural selection favors the allocation of finite resources to different functions maximizing fitness. In this sense, some functions may decrease whereas others increase when resources are limited in a process called a trade-off. However, a great var...

  • Article
  • Open Access
1 Citations
611 Views
21 Pages

Blue mold of pome fruit, caused by Penicillium expansum, is controlled through postharvest applications of thiabendazole (TBZ), pyrimethanil (PYR), and fludioxonil (FDL). However, multi-fungicide-resistant isolates have emerged in the U.S. Pacific No...

  • Article
  • Open Access
15 Citations
3,542 Views
15 Pages

28 January 2023

Ecosystems provide multiple valuable services that play an essential role in preventing meteorological risks, combating sandy land expansion, and ensuring sustainable development in the West Liao River Basin. The trade-off among ecosystem services (E...

  • Article
  • Open Access
13 Citations
4,257 Views
40 Pages

An Inventive Method for Eco-Efficient Operation of Home Energy Management Systems

  • Bilal Hussain,
  • Nadeem Javaid,
  • Qadeer Ul Hasan,
  • Sakeena Javaid,
  • Asif Khan and
  • Shahzad A. Malik

8 November 2018

A demand response (DR) based home energy management systems (HEMS) synergies with renewable energy sources (RESs) and energy storage systems (ESSs). In this work, a three-step simulation based posteriori method is proposed to develop a scheme for eco...

  • Article
  • Open Access
10 Citations
3,135 Views
12 Pages

9 September 2019

The alleles responsible for herbicide resistance in weeds can result in a fitness cost within affected plants. Over 200 cases of resistance to triazine herbicides have been confirmed in a wide range of weed species globally. In New Zealand, Chenopodi...

  • Article
  • Open Access
4 Citations
2,864 Views
15 Pages

Trade-Offs between Temperature and Fitness in Euschistus heros (Fabricius) (Hemiptera: Pentatomidae): Implications for Mass Rearing and Field Management

  • Ana Paula Frugeri Barrufaldi,
  • Rafael Hayashida,
  • William Wyatt Hoback,
  • Leon G. Higley,
  • Jose Romario de Carvalho and
  • Regiane Cristina de Oliveira

10 May 2023

The brown stink bug, Euschistus heros (Fabricius, 1798) (Hemiptera: Pentatomidae), is one of the most abundant soybean stink bug pests in Brazil. Temperature is a key factor that affects its development and reproduction, and fluctuating temperatures...

  • Article
  • Open Access
3 Citations
2,965 Views
12 Pages

31 January 2021

The study of fitness costs of insecticide resistance mutations in Aedes aegypti has generally been focused on life history parameters such as fecundity, mortality, and energy reserves. In this study we sought to investigate whether trade-offs might a...

  • Article
  • Open Access
8 Citations
2,599 Views
13 Pages

31 October 2021

The ‘Every Earthquake a Precursor According to Scale’ (EEPAS) medium-term earthquake forecasting model is based on the precursory scale increase (Ψ) phenomenon and associated scaling relations, in which the precursor magnitude MP is predictive of the...

  • Article
  • Open Access
2 Citations
2,662 Views
11 Pages

5 June 2022

Seed dormancy has been thought to be an important survival strategy to tune the seed dispersal timing. Although a theoretical trade-off between seed dormancy and dispersal is often proposed, empirical field evidence of the trade-off between seed dorm...

  • Article
  • Open Access
974 Views
26 Pages

29 August 2025

Revealing the trade-offs, synergies, and driving mechanisms among land use functions is essential for mitigating conflicts between functions, optimizing territorial spatial patterns, and providing policy support for regional sustainable development....

  • Review
  • Open Access
92 Citations
12,753 Views
15 Pages

Brassinosteroid Signaling in Plant–Microbe Interactions

  • Mei-Hui Yu,
  • Zhe-Ze Zhao and
  • Jun-Xian He

17 December 2018

As sessile organisms, plants are frequently exposed to different stress conditions caused by either biotic or abiotic factors. Understanding the mechanisms that underlie plant interaction with the biotic and abiotic environments is fundamental to bot...

  • Article
  • Open Access
2 Citations
5,083 Views
24 Pages

29 April 2022

Fitness landscapes are a powerful metaphor for understanding the evolution of biological systems. These landscapes describe how genotypes are connected to each other through mutation and related through fitness. Empirical studies of fitness landscape...

  • Article
  • Open Access
5 Citations
1,967 Views
19 Pages

Soil Nitrogen and Flooding Intensity Determine the Trade-Off between Leaf and Root Traits of Riparian Plant Species

  • Hang Zou,
  • Wanyu Wang,
  • Jinxia Huang,
  • Xiaohong Li,
  • Maohua Ma,
  • Shengjun Wu and
  • Cunfeng Zhao

29 March 2024

The investigation into trade-offs among plant functional traits sheds light on how plants strategically balance growth and survival when facing environmental stress. This study sought to evaluate whether trade-offs observed at both community and indi...

  • Feature Paper
  • Review
  • Open Access
59 Citations
9,667 Views
18 Pages

22 January 2019

Recent advances in perovskite nanocrystals-enhanced solid-state lighting (SSL) and liquid-crystal displays (LCDs) are reviewed. We first discuss the development, optical properties, and stability issue of materials, and then we evaluate the performan...

  • Article
  • Open Access
51 Citations
6,574 Views
27 Pages

Reduced-Complexity End-to-End Variational Autoencoder for on Board Satellite Image Compression

  • Vinicius Alves de Oliveira,
  • Marie Chabert,
  • Thomas Oberlin,
  • Charly Poulliat,
  • Mickael Bruno,
  • Christophe Latry,
  • Mikael Carlavan,
  • Simon Henrot,
  • Frederic Falzon and
  • Roberto Camarero

27 January 2021

Recently, convolutional neural networks have been successfully applied to lossy image compression. End-to-end optimized autoencoders, possibly variational, are able to dramatically outperform traditional transform coding schemes in terms of rate-dist...

  • Article
  • Open Access
6 Citations
3,534 Views
16 Pages

15 June 2021

Estimating costs of ejaculate production is challenging. Metabolic investment in ejaculates may come at the expense of other physiological functions and may negatively affect future reproduction and/or survival. These trade-offs are especially likely...

  • Perspective
  • Open Access
21 Citations
6,467 Views
8 Pages

Re-Envisioning Wildland Fire Governance: Addressing the Transboundary, Uncertain, and Contested Aspects of Wildfire

  • Brett Alan Miller,
  • Laurie Yung,
  • Carina Wyborn,
  • Maureen Essen,
  • Benjamin Gray and
  • Daniel R. Williams

8 April 2022

Wildfire is a complex problem because of the diverse mix of actors and landowners involved, uncertainty about outcomes and future conditions, and unavoidable trade-offs that require ongoing negotiation. In this perspective, we argue that addressing t...

  • Article
  • Open Access
14 Citations
4,991 Views
18 Pages

14 April 2020

This paper proposes a new method for the simultaneous determination of the optimal control parameters of proportional resonant controllers and the optimal design of the output filter of a grid-tied three-phase inverter. The proposed method, based on...

  • Article
  • Open Access
18 Citations
3,032 Views
16 Pages

FOPI/FOPID Tuning Rule Based on a Fractional Order Model for the Process

  • Helber Meneses,
  • Orlando Arrieta,
  • Fabrizio Padula,
  • Antonio Visioli and
  • Ramon Vilanova

This paper deals with the design of a control system based on fractional order models and fractional order proportional-integral-derivative (FOPID) controllers and fractional-order proportional-integral (FOPI) controllers. The controller design takes...

  • Article
  • Open Access
2,133 Views
18 Pages

Sensitivity of Fit Indices to Model Complexity and Misspecification in Exploratory Structural Equation Modeling

  • Xinya Liang,
  • Chunhua Cao,
  • Ji Li,
  • Ejike J. Edeh,
  • Jiaying Chen and
  • Wen-Juo Lo

Exploratory structural equation modeling (ESEM) allows items to cross-load on nontarget factors and provides flexibility in modeling multidimensional survey data. However, this flexibility comes at the cost of increased model complexity due to the es...

  • Article
  • Open Access
1 Citations
2,654 Views
10 Pages

Reproductive Output Reveals the Maternal Effects on Offspring Size-Number Trade-Off in Cultured Asian Yellow Pond Turtle (Mauremys mutica)

  • Yakun Wang,
  • Xiaoyou Hong,
  • Xiaoli Liu,
  • Wei Li,
  • Chen Chen,
  • Junxian Zhu,
  • Chengqing Wei,
  • Xinping Zhu and
  • Lingyun Yu

6 July 2023

Offspring size-number trade-off is a critical component of life-history theory and is important for further understanding the reproductive strategies of animals. The relationship between this trade-off and maternal size has been explored in several t...

  • Article
  • Open Access
2 Citations
1,774 Views
18 Pages

2 December 2024

Understanding the balance between robustness and evolvability is crucial in evolutionary dynamics. This study aims to determine how varying mutation rates and valley depths affect this interplay during adaptation. Using a two-peak fitness landscape m...

  • Proceeding Paper
  • Open Access
3 Citations
1,545 Views
7 Pages

Node Distribution Optimization in Positioning Sensor Networks through Memetic Algorithms in Urban Scenarios

  • Paula Verde,
  • Rubén Ferrero-Guillén,
  • Rubén Álvarez,
  • Javier Díez-González and
  • Hilde Perez

14 November 2020

Local Positioning Systems rely on ad-hoc node deployments which fit the environment characteristics in order to reduce system uncertainties. The obtainment of competitive results through these systems requires the solution of the Node Location Proble...

  • Article
  • Open Access
12 Citations
5,305 Views
18 Pages

A Sensor-Based Decision Support System for Transfemoral Socket Rectification

  • Michalis Karamousadakis,
  • Antonis Porichis,
  • Suranjan Ottikkutti,
  • DeJiu Chen and
  • Panagiotis Vartholomeos

28 May 2021

A decision support system (DSS) was developed that outputs suggestions for socket-rectification actions to the prosthetist, aiming at improving the fitness of transfemoral prosthetic socket design and reducing the time needed for the final socket des...

  • Article
  • Open Access
4 Citations
2,675 Views
10 Pages

Machine Learning Algorithm for Efficient Design of Separated Buffer Super-Junction IGBT

  • Ki Yeong Kim,
  • Tae Hyun Hwang,
  • Young Suh Song,
  • Hyunwoo Kim and
  • Jang Hyun Kim

28 January 2023

An improved structure for an Insulated Gate Bipolar Transistor (IGBT) with a separated buffer layer is presented in order to improve the trade-off between the turn-off loss (Eoff) and on-state voltage (Von). However, it is difficult to set efficient...

  • Feature Paper
  • Article
  • Open Access
1 Citations
2,018 Views
26 Pages

9 August 2024

Low temperature combustion (LTC) mitigates the nitrogen oxide (NOx) and particulate matter (PM) trade-off in conventional compression ignition engines. Significant research on LTC using partially premixed charge compression ignition (PPCI) has typica...

  • Review
  • Open Access
2 Citations
3,886 Views
23 Pages

19 April 2023

The evolutionary transition from single-celled to multicellular individuality requires organismal fitness to shift from the cell level to a cell group. This reorganization of fitness occurs by re-allocating the two components of fitness, survival and...

  • Communication
  • Open Access
36 Citations
7,391 Views
17 Pages

11 December 2020

Bee nutrition studies have focused on food quantity rather than quality, and on details of bee biology rather than on the functioning of bees in ecosystems. Ecological stoichiometry has been proposed for studies on bee nutritional ecology as an ecosy...

  • Article
  • Open Access
2 Citations
3,960 Views
12 Pages

Cosexuality Reduces Pollen Production and Fitness in Cannabis sativa L.

  • Sydney B. Wizenberg,
  • Jillian Muir-Guarnaccia and
  • Lesley G. Campbell

31 October 2023

Cannabis sativa L. is cultivated globally for its cannabinoid-dense inflorescences. Commercial preference for sinsemilla has led to the development of methods for producing feminized seeds through cross-pollination of cosexual (masculinized) female p...

  • Review
  • Open Access
33 Citations
8,260 Views
32 Pages

Biosphere Reserves’ Management Effectiveness—A Systematic Literature Review and a Research Agenda

  • Ana Filipa Ferreira,
  • Heike Zimmermann,
  • Rui Santos and
  • Henrik von Wehrden

8 July 2020

Research about biosphere reserves’ management effectiveness can contribute to better understanding of the existing gap between the biosphere reserve concept and its implementation. However, there is a limited understanding about where and how r...

  • Article
  • Open Access
7 Citations
5,055 Views
11 Pages

21 October 2023

Lithium-ion batteries, known for their high efficiency and high energy output, have gained significant attention as energy storage devices. Monitoring the state of charge through battery management systems plays a crucial role in enhancing the safety...

  • Review
  • Open Access
32 Citations
7,744 Views
36 Pages

30 July 2021

Plants are constantly threatened by pathogens, so have evolved complex defence signalling networks to overcome pathogen attacks. Post-translational modifications (PTMs) are fundamental to plant immunity, allowing rapid and dynamic responses at the ap...

  • Article
  • Open Access
11 Citations
9,922 Views
26 Pages

15 January 2025

Pneumonia remains a global health issue, creating the need for accurate detection methods for effective treatment. Deep learning models like ResNet50 show promise in detecting pneumonia from chest X-rays; however, their black-box nature limits the tr...

  • Article
  • Open Access
29 Citations
11,329 Views
21 Pages

Surface Mesh Reconstruction from Cardiac MRI Contours

  • Benjamin Villard,
  • Vicente Grau and
  • Ernesto Zacur

10 January 2018

We introduce a tool to build a surface mesh able to deal with sparse, heterogeneous, non-parallel, cross-sectional, non-coincidental contours and show its application to reconstruct surfaces of the heart. In recent years, much research has looked at...

  • Article
  • Open Access
18 Citations
3,439 Views
36 Pages

10 May 2023

Evolutionary and functional studies suggested that the emergence of the Omicron variants can be determined by multiple fitness trade-offs including the immune escape, binding affinity for ACE2, conformational plasticity, protein stability and alloste...

  • Article
  • Open Access
245 Views
30 Pages

5 January 2026

This work presents a practical approach to improve risk quantification for heavy-tailed insurance claims through model averaging and grid map visualization, addressing the drawbacks of traditional single “best” model selection commonly us...

  • Article
  • Open Access
7 Citations
4,388 Views
19 Pages

25 January 2021

Propylene is one of the world’s most important basic olefin raw material used in the production of a vast array of polymers and other chemicals. The need for high purity grade of propylene is essential and traditionally achieved by the very energy-in...

  • Article
  • Open Access
57 Citations
20,873 Views
33 Pages

Farming System Evolution and Adaptive Capacity: Insights for Adaptation Support

  • Jami L. Dixon,
  • Lindsay C. Stringer and
  • Andrew J. Challinor

27 February 2014

Studies of climate impacts on agriculture and adaptation often provide current or future assessments, ignoring the historical contexts farming systems are situated within. We investigate how historical trends have influenced farming system adaptive c...

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