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231 Results Found

  • Article
  • Open Access
1 Citations
2,989 Views
25 Pages

9 June 2025

We discuss the spread of epidemics caused by two viruses which cannot infect the same individual at the same time. The mathematical modeling of this epidemic leads to a kind of SIIRR model with two groups of infected individuals and two groups of rec...

  • Article
  • Open Access
17 Citations
3,732 Views
13 Pages

Uncertainty Modeling of a Modified SEIR Epidemic Model for COVID-19

  • Yanjin Wang,
  • Pei Wang,
  • Shudao Zhang and
  • Hao Pan

2 August 2022

Based on SEIR (susceptible–exposed–infectious–removed) epidemic model, we propose a modified epidemic mathematical model to describe the spread of the coronavirus disease 2019 (COVID-19) epidemic in Wuhan, China. Using public data,...

  • Article
  • Open Access
573 Views
15 Pages

Mathematical modeling allows taking into account registered and hidden infections to make correct predictions of epidemic dynamics and develop recommendations that can reduce the negative impact on public health and the economy. A model for visible a...

  • Article
  • Open Access
173 Citations
20,054 Views
12 Pages

8 March 2020

We develop a mathematical model to provide epidemic predictions for the COVID-19 epidemic in Wuhan, China. We use reported case data up to 31 January 2020 from the Chinese Center for Disease Control and Prevention and the Wuhan Municipal Health Commi...

  • Article
  • Open Access
753 Views
10 Pages

Mathematical Insights into the Spatio-Temporal Dynamics of Vector-Borne Diseases in Tropical Regions

  • Raouda Amine Oumar,
  • Mohamed Mbehou,
  • Mahamat Saleh Daoussa Haggar and
  • Benjamin Mampassi

Vector-borne diseases pose a significant public health challenge in tropical regions, where complex interactions between hosts, vectors, and the environment drive epidemic dynamics. In this study, we develop a spatio-temporal mathematical model to de...

  • Article
  • Open Access
18 Citations
4,908 Views
21 Pages

Unreported Cases for Age Dependent COVID-19 Outbreak in Japan

  • Quentin Griette,
  • Pierre Magal and
  • Ousmane Seydi

17 June 2020

We investigate the age structured data for the COVID-19 outbreak in Japan. We consider a mathematical model for the epidemic with unreported infectious patient with and without age structure. In particular, we build a new mathematical model and a new...

  • Review
  • Open Access
5 Citations
3,586 Views
18 Pages

A Scoping Review of Drug Epidemic Models

  • Wei Wang,
  • Sifen Lu,
  • Haoxiang Tang,
  • Biao Wang,
  • Caiping Sun,
  • Pai Zheng,
  • Yi Bai,
  • Zuhong Lu and
  • Yulin Kang

The phenomenon of drug epidemics has been a global issue in the past decades, causing enormous damages to the physical and mental health of drug users and social well-being. Despite great efforts to curb drug epidemics at the governmental or social l...

  • Article
  • Open Access
1,545 Views
36 Pages

10 October 2024

This study investigates a symmetric fractional-order epidemic model with time delays and non-monotonic incidence rates, considering two viral strains. By confirming the existence, uniqueness, and boundedness of the system’s solutions, the resea...

  • Article
  • Open Access
10 Citations
3,711 Views
34 Pages

20 October 2023

Infectious disease epidemics are challenging for medical and public health practitioners. They require prompt treatment, but it is challenging to recognize and define epidemics in real time. Knowing the prediction of an infectious disease epidemic ca...

  • Article
  • Open Access
8 Citations
2,949 Views
14 Pages

The SQEIRP Mathematical Model for the COVID-19 Epidemic in Thailand

  • Sowwanee Jitsinchayakul,
  • Usa Wannasingha Humphries and
  • Amir Khan

11 January 2023

The spread of COVID-19 started in late December 2019 and is still ongoing. Many countries around the world have faced an outbreak of COVID-19, including Thailand, which must keep an eye on the spread and find a way to deal with this extreme outbreak....

  • Article
  • Open Access
18 Citations
2,799 Views
15 Pages

A New COVID-19 Pandemic Model including the Compartment of Vaccinated Individuals: Global Stability of the Disease-Free Fixed Point

  • Isra Al-Shbeil,
  • Noureddine Djenina,
  • Ali Jaradat,
  • Abdallah Al-Husban,
  • Adel Ouannas and
  • Giuseppe Grassi

21 January 2023

Owing to the COVID-19 pandemic, which broke out in December 2019 and is still disrupting human life across the world, attention has been recently focused on the study of epidemic mathematical models able to describe the spread of the disease. The num...

  • Article
  • Open Access
22 Citations
35,053 Views
16 Pages

17 July 2020

This is a tutorial for the mathematical model of the spread of epidemic diseases. Beginning with the basic mathematics, we introduce the susceptible-infected-recovered (SIR) model. Subsequently, we present the numerical and exact analytical solutions...

  • Article
  • Open Access
21 Citations
6,254 Views
13 Pages

Neuraminidase Inhibitors in Influenza Treatment and Prevention–Is It Time to Call It a Day?

  • César Parra-Rojas,
  • Van Kinh Nguyen,
  • Gustavo Hernandez-Mejia and
  • Esteban A. Hernandez-Vargas

25 August 2018

Stockpiling neuraminidase inhibitors (NAIs) such as oseltamivir and zanamivir is part of a global effort to be prepared for an influenza pandemic. However, the contribution of NAIs for the treatment and prevention of influenza and its complications i...

  • Review
  • Open Access
10 Citations
5,234 Views
55 Pages

11 August 2024

Mathematical models play a crucial role in evaluating real-life processes qualitatively and quantitatively. They have been extensively employed to study the spread of diseases such as hepatitis B, COVID-19, influenza, and other epidemics. Many resear...

  • Article
  • Open Access
15 Citations
4,018 Views
28 Pages

24 July 2022

Data from the World Health Organization indicate that Bulgaria has the second-highest COVID-19 mortality rate in the world and the lowest vaccination rate in the European Union. In this context, to find the crucial epidemiological parameters that cha...

  • Article
  • Open Access
5 Citations
3,143 Views
21 Pages

17 May 2021

This paper addresses the problem of describing the spread of COVID-19 by a mathematical model introducing all the possible control actions as prevention (informative campaign, use of masks, social distancing, vaccination) and medication. The model ad...

  • Article
  • Open Access
11 Citations
3,796 Views
18 Pages

28 February 2023

Lassa fever is a deadly viral illness that is endemic in some parts of West Africa, including Nigeria. A deterministic model in the form of a non-linear system of differential equations is developed to analyse the dynamics and possible control of the...

  • Article
  • Open Access
4 Citations
2,044 Views
10 Pages

The full-scale invasion of Ukraine caused an unprecedented number of refugees after 24 February 2022. To estimate the influence of this humanitarian disaster on the COVID-19 pandemic dynamics, the smoothed daily numbers of cases in Ukraine, the UK, P...

  • Article
  • Open Access
25 Citations
4,333 Views
36 Pages

7 October 2020

This paper firstly studies an SIR (susceptible-infectious-recovered) epidemic model without demography and with no disease mortality under both total and under partial quarantine of the susceptible subpopulation or of both the susceptible and the inf...

  • Article
  • Open Access
8 Citations
4,350 Views
10 Pages

16 March 2021

Simple mathematical tools are needed to quantify the threat posed by emerging and re-emerging infectious disease outbreaks using minimal data capturing the outbreak trajectory. Here we use mathematical analysis, simulation and COVID-19 epidemic data...

  • Article
  • Open Access
10 Citations
4,071 Views
18 Pages

Mathematical Modeling Evaluates How Vaccinations Affected the Course of COVID-19 Disease Progression

  • Eleftheria Tzamali,
  • Vangelis Sakkalis,
  • Georgios Tzedakis,
  • Emmanouil G. Spanakis and
  • Nikos Tzanakis

24 March 2023

The regulation policies implemented, the characteristics of vaccines, and the evolution of the virus continue to play a significant role in the progression of the SARS-CoV-2 pandemic. Numerous research articles have proposed using mathematical models...

  • Article
  • Open Access
6 Citations
2,515 Views
22 Pages

19 April 2023

Most biological processes take time to occur. In infectious diseases, such as malaria or chikungunya, there is a period of time between when a susceptible individual gets bitten by the vector, and when the individual develops the disease. These times...

  • Article
  • Open Access
3 Citations
3,862 Views
11 Pages

16 February 2019

The results presented in this paper deal with the existence of solutions of a first order fully coupled system of three equations, and they are split in two parts: 1. Case with coupled functional boundary conditions, and 2. Case with periodic boundar...

  • Article
  • Open Access
9 Citations
2,469 Views
15 Pages

Numerical Modeling and Symmetry Analysis of a Pine Wilt Disease Model Using the Mittag–Leffler Kernel

  • V. Padmavathi,
  • N. Magesh,
  • K. Alagesan,
  • M. Ijaz Khan,
  • Samia Elattar,
  • Mamdooh Alwetaishi and
  • Ahmed M. Galal

23 May 2022

The existence of man is dependent on nature, and this existence can be disturbed by either man-made devastations or by natural disasters. As a universal phenomenon in nature, symmetry has attracted the attention of scholars. The study of symmetry pro...

  • Article
  • Open Access
6 Citations
2,150 Views
29 Pages

Stability and Optimality Criteria for an SVIR Epidemic Model with Numerical Simulation

  • Halet Ismail,
  • Amar Debbouche,
  • Soundararajan Hariharan,
  • Lingeshwaran Shangerganesh and
  • Stanislava V. Kashtanova

15 October 2024

The mathematical modeling of infectious diseases plays a vital role in understanding and predicting disease transmission, as underscored by recent global outbreaks; to delve deep into the dynamic of infectious disease considering latent period presci...

  • Article
  • Open Access
2 Citations
1,770 Views
15 Pages

The study of contagion dynamics is a well-established domain within epidemiology, where the spread of infectious diseases is modeled and analyzed. In recent years, similar methodologies have been applied to the financial sector to understand and pred...

  • Article
  • Open Access
1,469 Views
23 Pages

CanKiwi: A Mechanistic Competition Model of Kiwifruit Bacterial Canker Disease Dynamics

  • Oussama Hadj Abdelkader,
  • Hadjer Bouzebiba,
  • Miguel G. Santos,
  • Danilo Pena,
  • António Pedro Aguiar and
  • Susana M. P. Carvalho

This paper proposes a mathematical model based on a mechanistic approach and previous research findings for the bacterial canker disease development in kiwifruit vines. This disease is a leading cause of severe damage to kiwifruit vines, particularly...

  • Article
  • Open Access
62 Citations
3,431 Views
13 Pages

Modified Predictor–Corrector Method for the Numerical Solution of a Fractional-Order SIR Model with 2019-nCoV

  • Wei Gao,
  • Pundikala Veeresha,
  • Carlo Cattani,
  • Chandrali Baishya and
  • Haci Mehmet Baskonus

In this paper, we analyzed and found the solution for a suitable nonlinear fractional dynamical system that describes coronavirus (2019-nCoV) using a novel computational method. A compartmental model with four compartments, namely, susceptible, infec...

  • Article
  • Open Access
6 Citations
3,210 Views
20 Pages

Modeling and Forecasting Cases of RSV Using Artificial Neural Networks

  • Myladis R. Cogollo,
  • Gilberto González-Parra and
  • Abraham J. Arenas

19 November 2021

In this paper, we study and present a mathematical modeling approach based on artificial neural networks to forecast the number of cases of respiratory syncytial virus (RSV). The number of RSV-positive cases in most of the countries around the world...

  • Article
  • Open Access
11 Citations
3,448 Views
13 Pages

Estimation of a Within-Herd Transmission Rate for African Swine Fever in Vietnam

  • Van Phan Le,
  • Nguyen Thi Lan,
  • Jose Tobias Canevari,
  • Juan Pablo Villanueva-Cabezas,
  • Pawin Padungtod,
  • Thi Bich Ngoc Trinh,
  • Van Tam Nguyen,
  • Caitlin N. Pfeiffer,
  • Madalene V. Oberin and
  • Simon M. Firestone
  • + 1 author

6 February 2023

We describe results from a panel study in which pigs from a 17-sow African swine fever (ASF) positive herd in Thái Bình province, Vietnam, were followed over time to record the date of onset of ASF signs and the date of death from ASF....

  • Article
  • Open Access
27 Citations
3,532 Views
21 Pages

23 February 2023

Monkeypox (mpox) is a zoonotic viral disease that has caused recurring outbreaks in West Africa. The current global mpox virus (mpoxv) epidemic in endemic and non-endemic areas has seriously threatened public health. In this study, we design an SEIR-...

  • Article
  • Open Access
3 Citations
3,806 Views
24 Pages

3 December 2019

We use a new modelling approach to predict the cumulative impact of Phytophthora ramorum on the dynamic distribution of tanoak (Notholithocarpus densiflorus) and other tree species in coastal-Californian forest-communities. We explore the effectivene...

  • Article
  • Open Access
9 Citations
4,954 Views
12 Pages

Elevating herd immunity level against rubella is essential to prevent congenital rubella syndrome (CRS). Insufficient vaccination coverage left susceptible pockets among adults in Japan, and the outbreak of rubella from 2012 to 2013 resulted in 45 ob...

  • Article
  • Open Access
8 Citations
1,677 Views
9 Pages

1 October 2024

In this paper, we propose a novel normalized time-fractional susceptible–infected–removed (SIR) model that incorporates memory effects into epidemiological dynamics. The proposed model is based on a newly developed normalized time-fractio...

  • Article
  • Open Access
544 Views
27 Pages

A spatiotemporal transmission epidemic model is proposed based on human mobility, spatial factors of population migration across multiple regions, individual protection, and government quarantine measures. First, the model’s basic reproduction...

  • Article
  • Open Access
3,217 Views
20 Pages

Heterogeneities of individual attributes and behaviors play an important role in the complex process of epidemic spreading. Compared to differential equation-based system dynamical models of infectious disease transmission, individual-based epidemic...

  • Review
  • Open Access
12 Citations
4,866 Views
23 Pages

Reaction–Diffusion Equations in Mathematical Models Arising in Epidemiology

  • Vasyl’ Davydovych,
  • Vasyl’ Dutka and
  • Roman Cherniha

7 November 2023

The review is devoted to an analysis of mathematical models used for describing epidemic processes. Our main focus is on the models that are based on partial differential equations (PDEs), especially those that were developed and used for the COVID-1...

  • Article
  • Open Access
4 Citations
2,125 Views
25 Pages

23 June 2023

We developed a mathematical model to study the effects of non-pharmaceutical interventions (NPIs) on the dynamics of an epidemic. The level of intervention was assessed as a fraction of the population being isolated and depended on the level of incid...

  • Article
  • Open Access
2 Citations
2,387 Views
23 Pages

7 July 2023

Based on China’s summary of three years of experience and measures in the prevention and control of the COVID-19 epidemic, we have built a COVID-19 prevention and control model integrating health and medical detection, big data information tech...

  • Article
  • Open Access
1,391 Views
11 Pages

Modeling the Dynamic of Multiwave Diseases: The Model of Hand, Foot and Mouth Disease

  • Patrice Ravel,
  • Nghia Ngu Duy,
  • Guilhem Kister,
  • Le Thi Song Huong,
  • Ankit Dwivedi,
  • Christian A. Devaux,
  • Tran Nhu Duong,
  • Nguyen Tran Hien,
  • Laurent Gavotte and
  • Emmanuel Cornillot
  • + 1 author

29 July 2024

An HFMD outbreak spread over the city of Hải Phòng from summer 2011 to autumn 2012. This epidemic was chosen because it was the very first HFMD epidemic in North Vietnam, eliminating thus interferences with previous outbreaks. This epide...

  • Article
  • Open Access
2 Citations
2,130 Views
15 Pages

12 October 2022

The calculation of the probability of a minor outbreak is crucial in analyzing a stochastic epidemic model. For stochastic epidemic models with fixed delays, the linear chain trick is applied to transform the delayed models into a family of ODE model...

  • Article
  • Open Access
5 Citations
2,544 Views
12 Pages

9 December 2022

A local performance of the SIR model on actual data is introduced. A good approximation of the SIR model parameters in Saudi Arabia during a period of 275 days (the first of April 2020 to the end of December 2020) is determined. The parameters are es...

  • Article
  • Open Access
8 Citations
3,886 Views
14 Pages

11 December 2015

We consider a mosquito-borne epidemic model, where the adoption by individuals of insecticide–treated bed–nets (ITNs) is taken into account. Motivated by the well documented strong influence of behavioral factors in ITNs usage, we propose a mathemati...

  • Article
  • Open Access
1,565 Views
17 Pages

23 September 2023

Mathematical modeling in epidemiology, biology, and life sciences requires the use of stochastic models. In this paper, we derive a competitive two-strain stochastic SIR epidemic model by considering the change in state of the epidemic process due to...

  • Article
  • Open Access
15 Citations
6,030 Views
24 Pages

Mathematical Modeling and Characterization of the Spread of Chikungunya in Colombia

  • Gilberto C. González-Parra,
  • Diego F. Aranda,
  • Benito Chen-Charpentier,
  • Miguel Díaz-Rodríguez and
  • Jaime E. Castellanos

The Chikungunya virus is the cause of an emerging disease in Asia and Africa, and also in America, where the virus was first detected in 2006. In this paper, we present a mathematical model of the Chikungunya epidemic at the population level that inc...

  • Article
  • Open Access
3 Citations
2,046 Views
28 Pages

Modeling COVID-19 Disease with Deterministic and Data-Driven Models Using Daily Empirical Data in the United Kingdom

  • Janet O. Agbaje,
  • Oluwatosin Babasola,
  • Kabiru Michael Adeyemo,
  • Abraham Baba Zhiri,
  • Aanuoluwapo Joshua Adigun,
  • Samuel Adefisoye Lawal,
  • Oluwole Adegoke Nuga,
  • Roseline Toyin Abah,
  • Umar Muhammad Adam and
  • Kayode Oshinubi

18 February 2024

The COVID-19 pandemic has had a significant impact on countries worldwide, including the United Kingdom (UK). The UK has faced numerous challenges, but its response, including the rapid vaccination campaign, has been noteworthy. While progress has be...

  • Article
  • Open Access
14 Citations
6,035 Views
19 Pages

22 April 2021

Mathematical models of the spread of epidemic diseases are studied, paying special attention to networks. We treat the Susceptible-Infected-Recovered (SIR) model and the Susceptible-Exposed-Infectious-Recovered (SEIR) model described by differential...

  • Article
  • Open Access
9 Citations
5,801 Views
45 Pages

22 March 2024

The susceptible–infected–recovered–vaccinated–deceased (SIRVD) epidemic compartment model extends the SIR model to include the effects of vaccination campaigns and time-dependent fatality rates on epidemic outbreaks. It encomp...

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