Search Results (1,353)

Histotripsy is a novel, noninvasive, non-thermal technology invented in 2004 for the precise destruction of biologic tissue. It offers a powerful alternative to more conventional thermal or surgical interventions. Using short-pulse, low-duty cycle ultrasonic waves, histotripsy creates cavitation bubble clouds that selectively and precisely destroy targeted tissue in a predefined volume while sparing critical structures like bile ducts, ureters, and blood vessels. Such precision is of value when treating tumors near vital structures. The FDA has cleared histotripsy for the treatment of all liver tumors. Major medical centers are currently spearheading clinical trials, and some institutions have already integrated the technology into patient care. Histotripsy is now being studied for a host of other cancers, including primary kidney and pancreatic tumors. Preclinical murine and porcine models have already revealed promising outcomes. One of histotripsy’s primary advantages is its non-thermal mechanical actuation. This feature allows it to circumvent the limitations of heat-based techniques, including the heat sink effect and unpredictable treatment margins near sensitive tissues. In addition to its non-invasive ablative capacities, it is being preliminarily explored for its potential to induce immunomodulation and promote abscopal inhibition of distant, untreated tumors through CD8+ T cell responses. Thus, it may provide a multilayered therapeutic effect in the treatment of cancer. Histotripsy has the potential to improve precision and outcomes across a multitude of specialties, from oncology to cardiovascular medicine. Continued trials are crucial to further expand its applications and validate its long-term efficacy. Due to the speed of recent developments, the goal of this review is to provide a comprehensive and updated overview of histotripsy. It will explore its physics-based mechanisms, differentiating it from similar technologies, discuss its clinical applications, and examine its advantages, limitations, and future. Full article

Dual-active bridge (DAB) converters have emerged as a preferred topology in electric vehicle charging and energy storage applications, owing to their structurally symmetric configuration and intrinsic galvanic isolation capabilities. However, conventional triple-phase shift (TPS) control strategies face significant challenges in maintaining high efficiency across ultra-wide output voltage and load ranges. To exploit the inherent structural symmetry of the DAB topology, a symmetric optimization strategy based on triple-phase shift (SOS-TPS) is proposed. The method specifically targets the forward buck operating mode, where an optimization framework is established to minimize the root mean square (RMS) current of the inductor, thereby addressing both switching and conduction losses. The formulation explicitly incorporates zero-voltage switching (ZVS) constraints and operating mode conditions. By employing the Karush–Kuhn–Tucker (KKT) conditions in conjunction with the Lagrange multiplier method (LMM), the refined control trajectories corresponding to various power levels are analytically derived, enabling efficient modulation across the entire operating range. In the medium-power region, full-switch ZVS is inherently satisfied. In the low-power operation, full-switch ZVS is achieved by introducing a modulation factor λ, and a selection principle for λ is established. For high-power operation, the strategy transitions to a conventional single-phase shift (SPS) modulation. Furthermore, by exploiting the inherent symmetry of the DAB topology, the proposed method reveals the symmetric property of modulation control. The modulation strategy for the forward boost mode can be efficiently derived through a duty cycle and voltage gain mapping, eliminating the need for re-derivation. To validate the effectiveness of the proposed SOS-TPS strategy, a 2.3 kW experimental prototype was developed. The measured results demonstrate that the method ensures ZVS for all switches under the full load range, supports ultra-wide voltage conversion capability, substantially suppresses RMS current, and achieves a maximum efficiency of 97.3%. Full article

IoT devices with sensors and actuators are frequently deployed in environments without access to the power grid. These devices are battery powered and might make use of energy harvesting if battery lifetime is too limited. This article focuses on automatically adapting the duty cycle frequency to the predicted available solar energy so that a continuous operation of IoT applications is guaranteed. The implementation is based on a low-cost solar control board that is integrated with the Serverless IoT Framework (SIF), which provides an event-based programming paradigm for microcontroller-based IoT devices. The paper presents a case study where the IoT device sleep time is pro-actively adapted to a predicted sequence of cloudy days to guarantee continuous operation. Full article

In this paper, a robust optimized controller is implemented in the photovoltaic generator system (PVGS). The PVGS is composed of individual photovoltaic (PV) cells, which convert solar energy to electrical energy. To optimize the efficiency of the PVGS under variable solar irradiance and temperatures, a maximum power point tracking (MPPT) controller is necessary. Additionally, the PVGS output voltage is typically low for many applications. To achieve the MPPT and to gain the output voltage, an increasing boost converter (IBC) is employed. Then, two issues should be considered in MPPT. At first, a smooth control signal for adjusting the duty cycle of the IBC is important. Another critical issue is the PVGS and IBC unknown sections, i.e., the total system uncertainty. Therefore, to address the system uncertainties and to regulate the smooth duty cycle of the converter, a robust dynamic sliding mode control (DSMC) is proposed. In DSMC, a low-pass integrator is placed before the system to suppress chattering and to produce a smooth actuator signal. However, this integrator increases the system states, and hence, a sliding mode observer (SMO) is proposed to estimate this additional state. The stability of the proposed control scheme is demonstrated using the Lyapunov theory. Finally, to demonstrate the effectiveness of the proposed method and provide a reliable comparison, conventional sliding mode control (CSMC) with the same proposed SMO is also implemented. Full article

The core loss of the ferrite-based magnetic components is usually characterized by the well-known Steinmetz equation and its derivatives. This occurs when the magnitude of the excitation signal is high enough; otherwise, the core loss is defined by the complex permeability. These two models are based on different assumptions, and thus, this paper aims to combine the large- and small-signal core loss models into a single, unified model. Moreover, the paper presents improvements to the existing state-of-the-art core loss model, specifically regarding the influence of the switching duty-cycle of rectangular excitation signals and the DC bias. Full article

Power converters in the smart grid systems are essential to link renewable energy sources with all grid appliances and equipment. However, this raises the possibility of electromagnetic interference (EMI) between the smart grid elements. Hence, spread spectrum (SS) modulation techniques have been used to mitigate the EMI peaks generated from the power converters. Consequently, the performance of the nearby communication systems is affected under the presence of EMI, which is not covered in many situations. In this paper, the behavior of the G3 Power Line Communication (PLC) channel is evaluated in terms of the Shannon–Hartley equation in the presence of SS-modulated EMI from a buck converter. The SS-modulation technique used is the Random Carrier Frequency Modulation with Constant Duty cycle (RCFMFD). Moreover, The analysis is validated by experimental results obtained with a test setup reproducing the parasitic coupling between the PLC system and the power converter. Full article

Selective catalytic reduction filter (SDPF) technology constitutes a critical methodology for controlling nitrogen oxide (NOx) and particulate matter emissions from light-duty diesel vehicles. A series of SDPFs with different sulfur poisoning times and concentrations were prepared using the worldwide harmonized light vehicles test cycle (WLTC). Bench testing revealed that sulfur poisoning diminished the catalyst’s NH₃ storage capacity, impaired the transient NOx reduction efficiency, and induced premature ammonia leakage. After multiple sulfur poisoning incidents, the NOx reduction performance stabilized. Higher SO₂ concentrations accelerated catalyst deactivation and hastened the attainment of this equilibrium state. The characterization results for the catalyst indicate that the catalyst accumulated the same sulfur content after tail gas poisoning with different sulfur concentrations and that sulfur existed in the form of SO₄²⁻. The sulfur species in low-sulfur-poisoning-concentration catalysts mainly included sulfur ammonia and sulfur copper species, while high-sulfur-poisoning-concentration catalysts contained a higher proportion of sulfur copper species. Neither species type significantly altered the zeolite coating’s crystalline structure. Sulfur ammonia species could easily lead to a significant decrease in the specific surface area of the catalyst, which could be decomposed at 500 °C to achieve NOx reduction performance regeneration. In contrast, sulfur copper species required higher decomposition temperatures (600 °C), achieving only partial regeneration. Full article

As public concern over environmental pollution and the urgent need for sustainable development grow, the popularity of new-energy vehicles has increased. Hybrid electric vehicles (HEVs) represent a significant segment of this movement, undergoing robust development and playing an important role in the global transition towards sustainable mobility. Among the various factors affecting the fuel economy of HEVs, energy management strategies (EMSs) are particularly critical. With continuous advancements in vehicle communication technology, vehicles are now equipped to gather real-time traffic information. In response to this evolution, this paper proposes an optimization method for the adaptive equivalent consumption minimization strategy (A-ECMS) equivalent factor that incorporates traffic information and efficient optimization algorithms. Building on this foundation, the proposed method integrates the charge depleting–charge sustaining (CD-CS) strategy to create a combined EMS that leverages traffic information. This approach employs the CD-CS strategy to facilitate vehicle operation in the absence of comprehensive global traffic information. However, when adequate global information is available, it utilizes both the CD-CS strategy and the A-ECMS for vehicle control. Simulation results indicate that this combined strategy demonstrates effective performance, achieving fuel consumption reductions of 5.85% compared with the CD-CS strategy under the China heavy-duty truck cycle, 4.69% under the real vehicle data cycle, and 3.99% under the custom driving cycle. Full article

The rapid expansion of Internet of Things (IoT) devices has heightened the demand for lightweight and secure cryptographic mechanisms suitable for resource-constrained environments. While SHA-256 remains a widely used standard, the emergence of SHA-3 particularly the KangarooTwelve variant offers potential benefits in flexibility and post-quantum resilience for lightweight resource-constrained devices. This paper presents a comparative evaluation of the energy costs associated with SHA-256 and SHA-3 hashing in Contiki 3.0, using three generationally distinct IoT platforms: Sky Mote, Z1 Mote, and Wismote. Unlike previous studies that rely on hardware acceleration or limited scope, our work conducts a uniform, software-only analysis across all motes, employing consistent radio duty cycling, ContikiMAC (a low-power Medium Access Control protocol) and isolating the cryptographic workload from network overhead. The empirical results from the Cooja simulator reveal that while SHA-3 provides advanced security features, it incurs significantly higher CPU and, in some cases, radio energy costs particularly on legacy hardware. However, modern platforms like Wismote demonstrate a more balanced trade-off, making SHA-3 viable in higher-capability deployments. These findings offer actionable guidance for designers of secure IoT systems, highlighting the practical implications of cryptographic selection in energy-sensitive environments. Full article

Due to the limitations of current battery technologies—such as lower energy density and high cost compared to fossil fuels—electric vehicles (EVs) face constraints in applications requiring extended range or heavy payloads, such as refuse trucks. As a midterm solution, hybrid electric vehicles (HEVs) combine internal combustion engines (ICEs) and electric powertrains to enable flexible energy usage, particularly in urban duty cycles characterized by frequent stopping and idling. This study introduces a model-based energy management strategy using the Equivalent Consumption Minimization Strategy (ECMS), tailored for a retrofitted series hybrid refuse truck. A conventional ISUZU NPR 10 truck was instrumented to collect real-world driving and operational data, which guided the development of a vehicle-specific ECMS controller. The proposed strategy was evaluated over five driving cycles—including both standardized and measured urban scenarios—under varying load conditions: Tare Mass (TM) and Gross Vehicle Mass (GVM). Compared with a rule-based control approach, ECMS demonstrated up to 14% improvement in driving range and significant reductions in exhaust gas emissions (CO, NO_x, and CO₂). The inclusion of auxiliary load modeling further enhances the realism of the simulation results. These findings validate ECMS as a viable strategy for optimizing fuel economy and reducing emissions in hybrid refuse truck applications. Full article

In the process of machining an aluminum matrix silicon carbide (SiCp/Al) composite material using wire electric discharge machining (WEDM), the thermal conductivity and dielectric properties of working fluid, such as discharge medium and cool carrier, directly determine the material removal rate (MRR) and surface roughness (R_a). In this paper, graphene-working fluid is innovatively used as working medium to optimize the discharge process due to its high thermal conductivity and field emission characteristics. The single-factor experiments show that graphene can increase the MRR by 11.16% and decrease the R_a by 29.96% compared with traditional working fluids. In order to analyze the multi-parameter coupling effect, an L16 (4⁴) orthogonal test is further designed, and the effects of the pulse width (T_on), duty cycle (DC), power tube number (PT), and wire speed (WS) on the MRR and R_a are determined using a signal-to-noise analysis. Based on a gray relational grade analysis, a multi-objective optimization model was established, and the priority of the MRR and R_a was determined using an AHP, and finally the optimal parameter combination (T_on = 22 μs, DC = 1:4, PT = 3, WS = 2) was obtained. Full article

Reactive oxygen–nitrogen species (RONS) production in a Peltier-cooled hybrid dielectric barrier discharge (HDBD) reactor operated with humid air is characterized. Fourier-transform infrared spectroscopy (FTIR) is used to determine the RONS in the HDBD-produced gases. The presence of molecules ${\mathrm{O}}_3$, ${\mathrm{NO}}_2$, ${\mathrm{N}}_2$O, ${\mathrm{N}}_2{\mathrm{O}}_5$, and ${\mathrm{HNO}}_3$ is evaluated. The influence of HDBD reactor operation parameters on the FTIR result is discussed. The strongest influence of Peltier cooling on RONS chemistry is reached at conditions related to a high specific energy input (SEI): high voltage and duty cycle of plasma width modulation (PWM), and low gas flow. Both PWM and Peltier cooling can achieve a change in the chemistry from oxygen-based to nitrogen-based. ${\mathrm{N}}_2{\mathrm{O}}_5$ and ${\mathrm{HNO}}_3$ are detected at a low humidity of 7% in the reactor input air but not at humidity exceeding 90%. In addition to the FTIR analysis, the plasma-activated water (PAW) is investigated. PAW is produced by bubbling the HDBD plasma gas through 12.5 mL of distilled water in a closed-loop circulation at a high SEI. Despite the absence of ${\mathrm{N}}_2{\mathrm{O}}_5$ and ${\mathrm{HNO}}_3$ in the gas phase, the acidity of the PAW is increased. The pH value decreases on average by 0.12 per minute. Full article

In the Direct Energy Deposition (DED) process, the deposited material experiences intricate thermo-mechanical processes. Subsequent thermal cycling can trigger Dynamic Recrystallization (DRX) under suitable conditions, with specific strain and temperature parameters facilitating grain refinement and homogenization. While prior research has examined the impact of thermal cycling in continuous wave (CW) lasers on DRX in 316 L stainless steel deposits, this study delves into the effects of pulsed wave (PW) laser thermal cycling on DRX. Here, the thermo-mechanical response to PW cyclic thermal loading is empirically assessed, and the evolution of microstructure, grain morphology, geometric dislocation density (GND), and misorientation map during PW DED of 316 L stainless steel is scrutinized. Findings reveal that DRX is activated between the 8th and 44th thermal cycles, with temperatures fluctuating in the range of 680 K–750 K–640 K and grains evolving within a 5.6%–6.2%–5.2% strain range. After 90 thermal cycles, the grain microstructure undergoes significant alteration. Throughout the thermal cycling, dynamic recovery (DRV) occurs, marked by sub-grain formation and low-angle grain boundaries (LAGBs). Continuous dynamic recrystallization (CDRX) accompanies discontinuous dynamic recrystallization (DDRX), with LAGBs progressively converting into high-angle grain boundaries (HAGBs). Elevated temperatures and accumulated strain drive dislocation movement and entanglement, augmenting GND. The study also probes the influence of frequency and duty cycle on grain microstructure, finding that low pulse frequency spurs CDRX, high pulse frequency favors DRV, and the duty cycle has minimal impact on grain microstructure under PW cyclic thermal load. Full article

In current and future fusion devices, detecting hydrogen isotopes, particularly tritium and deuterium, implanted or redeposited on the surface of Plasma-Facing Components (PFCs) will be increasingly important to ensure safe machine operations. The Laser-Induced Breakdown Spectroscopy (LIBS) technique has proven capable of performing this task directly in situ, without handling or removing PFCs, thus limiting analysis times and increasing the machine’s duty cycle. To increase sensitivity and the ability to discriminate between isotopes, LIBS analysis can be performed under different background gases at atmospheric pressure, such as air, He, and Ar. In this work, we present the results obtained on tungsten coatings enriched with deuterium and/or hydrogen as a deuterium–tritium nuclear fuel simulant, measured with the LIBS technique in air, He, and Ar at atmospheric pressure, and discuss the pros and cons of their use. The results obtained demonstrate that both He and Ar can improve the LIBS signal resolution of the hydrogen isotopes compared to air. However, using Ar has the additional advantage that the same procedure can also be used to detect He implanted in PFCs as a product of fusion reactions without any interference. Finally, the LIBS signal in an Ar atmosphere increases in terms of the signal-to-noise ratio (SNR), enabling the use of less energetic laser pulses to improve performance in depth profiling analyses. Full article

Background: Gallbladder hypomotility is a key pathogenic factor in cholelithiasis. Non-invasive interventions to enhance gallbladder contractility remain limited. Ultrasound therapy has shown promise in various muscular disorders, but its effects on gallbladder function are unexplored. Methods: This study employed low-intensity pulsed ultrasound (LIPUS) at a 3 MHz frequency and 0.8 W/cm² intensity with a 20% duty cycle to irradiate the gallbladder region of fasting guinea pigs. Gallbladder contractile function was evaluated through multiple complementary approaches: in vivo assessment via two-dimensional/three-dimensional ultrasound imaging to monitor volumetric changes; quantitative functional evaluation using nuclear medicine scintigraphy (^99mTc-HIDA); and ex vivo experiments including isolated gallbladder muscle strip tension measurements, histopathological analysis, α-smooth muscle actin (α-SMA) immunohistochemistry, and intracellular calcium fluorescence imaging. Results: Ultrasound significantly enhanced gallbladder emptying, evidenced by the volume reduction and increased ejection fraction. Scintigraphy confirmed accelerated bile transport in treated animals. Ex vivo analyses demonstrated augmented contractile force, amplitude, and frequency in ultrasound-treated smooth muscle. Histological examination revealed smooth muscle hypertrophy, α-SMA upregulation, and elevated intracellular calcium levels. Extended ultrasound exposure produced sustained functional improvements without tissue damage. Conclusions: Ultrasound effectively enhances gallbladder contractile function through mechanisms involving smooth muscle structural modification and calcium signaling modulation. These findings establish the experimental foundation for ultrasound as a promising non-invasive therapeutic approach to improve gallbladder motility and potentially prevent gallstone formation. Full article