Background: Formulating poorly water-soluble drugs poses significant challenges due to their limited solubility and bioavailability. Loratadine (LTD), classified as a BCS II molecule, exhibits notably low solubility, leading to reduced bioavailabilit...
Many people who have had a near-death experience (NDE) describe, as part of it, a disturbed sense of having a “distinct self”. However, no empirical studies have been conducted to explore the frequency or intensity of these effects. We surveyed 100 N...
In this study, the release behavior of Pb(II) ions from the galena surface and their occurrence forms in the migration process under acid and alkaline conditions were investigated by dissolution experiment, the density functional theory (DFT) calcula...
Gastric mechanical stress often impacts drug dissolution from solid oral dosage forms, but in vitro experiments cannot recreate the substantial variability of gastric motility in a reasonable time. This study, for the first time, combines a novel dis...
Although vanadinite (Pb5(VO4)3Cl) occurs in abundance in various terrestrial geochemical systems of natural and anthropogenic origin and is seriously considered as a potential nuclear waste sequestering agent, its actual application is severely limit...
The present paper deals with a field experiments on evaporite rock samples and groundwater investigations in the Quinis test site, a hamlet of the Enemonzo municipality in NE Italy, were sinkholes occurred in the past and are still occurring causing...
Determining the dissolution rates of carbonate rocks is vital to advancing our understanding of cave, karst, and landscape processes. Furthermore, the role of carbonate dissolution is important for the global carbon budget and climate change. A labor...
The turbine mortise is a critical structural feature of turbine disks, and its manufacturing quality directly determines the performance and service life of aircraft engines. With the increasing application of advanced nickel-based superalloys, sever...
The mechanochemical synthesis of drug–drug solid forms containing metformin hydrochloride (MET·HCl) and thiazide diuretics hydrochlorothiazide (HTZ) or chlorothiazide (CTZ) is reported. Characterization of these new systems indicates formation of bin...
We studied the dependence of dissolution of silk fibroin (SF) in mixtures of DMSO with ionic liquids (ILs) on the temperature (T = 40 to 80 °C) and DMSO mole fraction (χDMSO = 0.5 to 0.9). The ILs included BuMeImAcO, C3OMeImAcO, AlBzMe2NAcO,...
Multilayer plastic packaging waste (MPPW) represents a major challenge for waste management due to its widespread use in single-use applications and its complex, heterogeneous structure. Variations in polymer composition, layer thickness and number o...
This study explores for the first time the impact of chitosan (CS) with varying molecular weights (MW), orange peel extract concentration, and hydroxypropyl methylcellulose (HPMC) content on the formulation of buccal tablets for treating oral infecti...
Carbonate reservoirs are attractive targets for geological CO2 storage due to their high storage capacity. However, CO2 injection can induce complex geochemical reactions that alter reservoir petrophysical properties in unpredictable ways. This study...
Leaching in cement-based materials and dissolution in rocks are important problems in civil engineering. In the past century, concrete damage caused by leaching have occurred worldwide. And, rock dissolution is usually the main cause of karst rock er...
During Precambrian subduction, banded iron formations (BIFs) may have represented an early significant input of carbonates and atmospheric sulfur into the lithospheric mantle, initiated the formation of carbonatite melts and probably triggered mantle...
Background/Objectives: We conducted this study to develop a generic amiodarone tablet pharmaceutically equivalent to the reference drug. This development is crucial for securing a stable supply chain for this orphan drug, which currently faces domest...
Carbon dioxide density-driven dissolution in a water-filled laboratory flume of the dimensions 60 cm length, 40 cm height, 1 cm thickness, was visualized using a pH-sensitive color indicator. We focus on atmospheric pressure conditions, like in caves...
In this study, an Al2O3-40TiO2 coating was deposited on 20MnNiMo steel via atmospheric plasma spraying. The corrosion behavior of the coating was investigated in both artificial seawater and a simulated environment with hydrogen sulfide and high pres...
Replacement of albite by sodium-rich, secondary phases is a common phenomenon, observed in different geological settings and commonly attributed to alkaline metasomatism. We investigated growth of nepheline and sodalite on albite in time series exper...
The descaling roller is a significant component in steel rolling production. Under harsh service conditions, the descaling roller is subjected to the dynamic impact caused by high-pressure water erosion and a high-temperature billet descaling process...
In nature, asbestos is often associated with minerals and other non-asbestiform morphologies thought to be harmless, but not much is known about the potential toxic effects of these phases. Therefore, the characterization of natural assemblages shoul...
The goal of this work is to assess the application of ultrasonic power to the reactive dissolution of limestone particles in an acidic environment; this would represent a novel method for improving wet Flue Gas Desulfurization industrial systems. In...
Physiologically based pharmacokinetic and absorption modeling are being used by industry and regulatory bodies to address various scientifically challenging questions. While there is high confidence in the prediction of exposure for the BCS class I d...
Coamorphous salt in a 1:1 ratio prepared by ball milling from Fluvastatin sodium (FLV) and Pioglitazone hydrochloride (PGZ·HCl) can be selectively formed by neat grinding (NG). Furthermore, the salt–cocrystal continuum was preferably for...
Metronidazole (MT) is an important drug available for Helicobacter pylori infection treatment. However, in the past few years, this drug has presented effective reduction for infection control, one of the most important reasons is attributed to the r...
Ball-milling using neat grinding (NG) or liquid-assisted grinding (LAG) by varying the polarity of the solvents allowed access to various drug–drug solid forms of pioglitazone hydrochloride (PGZ·HCl) and rosuvastatin calcium (RSV). Using...
Syngenetic fluid inclusions in natural diamonds are indicators of the composition of fluids responsible for growth and crystallization conditions. The chloride concentration in saline fluid inclusions of natural diamonds reaches 50 wt%. We study the...
The aim of this work was to investigate the evolutionary mechanisms of an artificial sedimentary agglomerate formed by cathodic polarization in natural seawater during its abandonment to a natural environment. Previous studies indicate that the miner...
Interaction of organic matter (OM) with soil mineral components plays a critical role in biophysical organization (aggregate structure) as well as in biogeochemical cycling of major elements. Of the mineral components, poorly-crystalline phases rich...
Deep to ultra-deep dolostone reservoirs may be substantially modified by organic-acid-bearing fluids, but the relationship between fluid-phase chemical signals and residual pore-system modification under paired temperature–pressure (T–P)...
Continuous dissolution of spent fuel is indeed one of the key technologies that can significantly improve the efficiency and stability of spent fuel reprocessing. The China Institute of Atomic Energy designed a prototype rotary drum dissolver, and th...
The long dissolution time and large dispensed volumes of oil repellent polymers in offshore oil fields lead to a great increase in the volume and number of dissolution and maturation tanks in the polymer formulation system. However, there is limited...
The removal of radionuclides from the primary coolant system of nuclear power plants occurs with the dissolution of corrosion metal oxide layers deposited with the radionuclides. Kinetic dissolution experiments were conducted with a synthetic magneti...
A new cocrystal of Norfloxacin, a poorly soluble fluoroquinolone antibiotic, has been synthetized by a solvent-mediated transformation experiment in toluene, using resorcinol as a coformer. The new cocrystal exists in both anhydrous and monohydrate f...
Chemical sequestration is one important manner of CCUS. The injection of CO2 into an oil reservoir can not only sequestrate CO2 but also raise the oil recovery factor. The performance of chemical sequestration of CO2 depends on the interaction betwee...
This paper investigates the dissolution of two biopolymers, cellulose and silk fibroin, in a mixture of 1-ethyl-3-methylimidazolium acetate (EmimAc) and dimethyl sulphoxide (DMSO). EmimAc is a promising environmentally friendly solvent currently in w...
The traditional hot-dip tinning processes face challenges in controlling excessive copper dissolution and interfacial instability. This study involved designing a dissolution experiment using the hot-dip tin plating process. Through microscopic chara...
This study investigates the effect of external vibration stimulation on CO2 dissolution behavior in heavy oil reservoirs, focusing on the influence of vibration frequency and cavity distribution within porous media. Experiments reveal that 5 Hz vibra...
Systematic investigation of filtrates and filter residues resulting from a 24 h treatment of metakaolin in different alkaline solutions were performed. On filtered metakaolin particles, inductively coupled plasma-optical emission spectrometry (ICP-OE...
Chengde City boasts a wealth of high-quality mineral water resources characterized by a high level of strontium (Sr), a low level of sodium, and low alkalinity. In order to study the mechanism of formation of Sr-bearing mineral water in Chengde and t...
During the solution heat treatment (SHT) process of aluminum alloys, precipitates dissolve into the matrix. To predict the dissolution time, modeling of isothermal dissolution of precipitates in 6061 aluminum alloy during SHT was conducted. A precipi...
Apatite (Ap) dissolution in diluted acids is well described in the literature, but in technological processes which use more concentrated acids, the reaction is fast, and it is complicated to follow the process kinetics. The relationship between pH c...
Understanding the mechanisms of mineral dissolution at the atomic scale is crucial for interpreting geochemical processes in soils and sediments, particularly those involving clay minerals. This study addresses the dissolution of pyrophyllite, a mode...
Phosphogypsum leachate significantly accelerates carbonate rock dissolution in karst regions. The dissolution mechanism of phosphogypsum leachate associated with carbonate rock interaction and the corresponding numerical simulation need further study...
The dissolution of dolomite can not only provide the chemical components in hot springs but also provide a high-quality reservoir for geothermal resources. However, there is still debate about the main controlling factors and mechanisms of the dissol...
This study investigates the effect of the particle size and solid-to-liquid ratio on the dissolution rate of magnesium (Mg) and silicon (Si) in heat-activated lizardite. The investigation was conducted under specific conditions: without the presence...
Understanding mineral dissolution is relevant for natural and industrial processes that involve the interaction of crystalline solids and fluids. The dissolution of slow dissolving minerals is typically surface controlled as opposed to diffusion/tran...
In order to reveal the acidification and dissolution characteristics of deep coal rock, core acidification and dissolution experiments are carried out based on low-field nuclear magnetic resonance technology to study the dissolution characteristics o...
Understanding the kinetics of peptide self-assembly is important because of the involvement of peptide amyloid fibrils in several neurodegenerative diseases. In this paper, we have studied the dissolution kinetics of self-assembled model peptide fibr...
Mineral dissolution is a dynamic process in which kinetics depend on the reactive surface area, orientation, and geometry of the dissolving mineral grain. Dissolution rate is, thus, not represented by a single value, but rather, by a spectrum that is...
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