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3 Results Found

  • Article
  • Open Access
29 Citations
7,735 Views
9 Pages
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Mild and Efficient Strontium Chloride Hexahydrate-Catalyzed Conversion of Ketones and Aldehydes into Corresponding gem- Dihydroperoxides by Aqueous H2O2

  • Davood Azarifar,
  • Kaveh Khosravi and
  • Fatemeh Soleimanei
Molecules2010, 15(3), 1433-1441;https://doi.org/10.3390/molecules15031433

8 March 2010

SrCl2·6H2O has been shown to act as an efficient catalyst for the conversion of aldehydes or ketones into the corresponding gem-dihydroperoxides (DHPs) by treatment with aqueous H2O2 (30%) in acetonitrile. The reactions proceed under mild and neutral...

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  • Article
  • Open Access
8 Citations
6,934 Views
13 Pages
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Anti-Oncogenic gem-Dihydroperoxides Induce Apoptosis in Cancer Cells by Trapping Reactive Oxygen Species

  • Yuki Kuranaga,
  • Nami Yamada,
  • Maiko Kashiwaya,
  • Moeko Nakamura,
  • Lei Cui,
  • Minami Kumazaki,
  • Haruka Shinohara,
  • Nobuhiko Sugito,
  • Kohei Taniguchi and
  • Yukihiro Akao
  • + 4 authors
Int. J. Mol. Sci.2016, 17(1), 71;https://doi.org/10.3390/ijms17010071

8 January 2016

Organic gem-dihydroperoxides (DHPs) and their derived peroxides have attracted a great deal of attention as potential anti-cancer agents. However, the precise mechanism of their inhibitory effect on tumors is unknown. To determine the mechanism of th...

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  • Article
  • Open Access
3 Citations
3,232 Views
14 Pages
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The Novel gem-Dihydroperoxide 12AC3O Suppresses High Phosphate-Induced Calcification via Antioxidant Effects in p53LMAco1 Smooth Muscle Cells

  • Naoko Takase,
  • Masatoshi Inden,
  • Shunsuke Hirai,
  • Yumeka Yamada,
  • Hisaka Kurita,
  • Mitsumi Takeda,
  • Eiji Yamaguchi,
  • Akichika Itoh and
  • Isao Hozumi
Int. J. Mol. Sci.2020, 21(13), 4628;https://doi.org/10.3390/ijms21134628

29 June 2020

The excessive intake of phosphate (Pi), or chronic kidney disease (CKD), can cause hyperphosphatemia and eventually lead to ectopic calcification, resulting in cerebrovascular diseases. It has been reported that reactive oxygen species (ROS), induced...

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