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121,132 Results Found

  • Article
  • Open Access
4 Citations
3,028 Views
11 Pages

Combined Effect of TID Radiation and Electrical Stress on NMOSFETs

  • Yanrong Cao,
  • Min Wang,
  • Xuefeng Zheng,
  • Enxia Zhang and ,
  • Ling Lv,
  • Liang Wang,
  • Maodan Ma,
  • Hanghang Lv,
  • Zhiheng Wang and
  • Yue Hao
  • + 8 authors+ 3 authors

29 October 2022

The combined effect of total ionizing dose (TID) and electrical stress is investigated on NMOSFETs. For devices bearing both radiation and electrical stress, the threshold voltage shift is smaller than those only bearing electrical stress, indicating...

(This article belongs to the Special Issue Advanced Packaging for Microsystem Applications)
  • Article
  • Open Access
15 Citations
4,983 Views
20 Pages

Global Spatial and Temporal Variation of the Combined Effect of Aerosol and Water Vapour on Solar Radiation

  • María Ángeles Obregón,
  • Antonio Serrano,
  • Maria João Costa and
  • Ana Maria Silva

15 February 2021

This study aims to calculate the combined and individual effects of the optical thickness of aerosols (AOT) and precipitable water vapour (PWV) on the solar radiation reaching the Earth’s surface at a global scale and to analyse its spatial and tempo...

(This article belongs to the Section Atmospheric Remote Sensing)
  • Article
  • Open Access
2 Citations
1,068 Views
20 Pages

Plasma Shielding Effect in Nanosecond/CW Combined Pulse Laser Ablation of Metals

  • Xianshi Jia,
  • Yuehao Cai,
  • Junyang Xu,
  • Lu Zhang and ,
  • Kai Li,
  • Xin Li,
  • Ke Sun,
  • Zhou Li and
  • Cong Wang
  • + 4 authors+ 0 author

13 March 2026

Combined pulse laser systems combining continuous-wave (CW) lasers and nanosecond pulsed lasers have shown clear advantages in metal ablation and surface modification. However, the plasma shielding effect induced by nanosecond pulses and the associat...

(This article belongs to the Section Manufacturing Processes and Systems)
  • Article
  • Open Access
44 Citations
5,030 Views
14 Pages

Combined Effect of Biopolymer and Fiber Inclusions on Unconfined Compressive Strength of Soft Soil

  • Chunhui Chen,
  • Kai Wei,
  • Jiayu Gu,
  • Xiaoyang Huang and ,
  • Xianyao Dai and
  • Qingbing Liu
  • + 1 author+ 0 author

17 February 2022

The utilizing of traditional chemical stabilizers could improve soil engineering properties but also results in brittle behavior and causes environmental problems. This study investigates the feasibility of the combined utilization of an ecofriendly...

(This article belongs to the Special Issue Applications of Biocompatible and Biodegradable Polymers and Their Composites)
  • Article
  • Open Access
25 Citations
8,106 Views
24 Pages

In Vitro and In Vivo Study of Combined Effect of Some Algerian Medicinal Plants and Probiotics against Helicobacter pylori

  • Bouhenni Hasna,
  • Hemida Houari,
  • Doukani Koula,
  • Spinu Marina and ,
  • Ungureanu Emilia and
  • Boumezrag Assia
  • + 1 author+ 0 author

Helicobacter pylori causes gastritis, peptic ulcers and gastric cancer and affects more than half of the world’s population. Although this infection can have serious consequences, no novel cure or remedy have been discovered, the present therap...

(This article belongs to the Special Issue Antimicrobial Compounds from Alternative Sources 2.0)
  • Article
  • Open Access
676 Views
17 Pages

Bactericidal Effect of Low Temperature Plasma Combined with Slightly Acidic Electrolyzed Water Against Listeria monocytogenes

  • Jiayi Shi,
  • Zhanfei Wang,
  • Bing Li,
  • Xingzhe Zhang and ,
  • Zhanpeng Wu,
  • Jianxiong Hao and
  • Tongjiao Wu
  • + 2 authors+ 0 author

22 April 2026

This study investigated the bactericidal effect and examined the associated cellular damage of low temperature plasma (LTP) combined with slightly acidic electrolyzed water (SAEW) against Listeria monocytogenes. Single-factor experiments were conduct...

(This article belongs to the Section Food Microbiology)
  • Article
  • Open Access
39 Citations
5,839 Views
17 Pages

10 November 2021

Cerium oxide nanoparticles (CeO2 NPs) and zinc oxide nanoparticles (ZnO NPs) are emerging pollutants that are likely to occur in the contemporary environment. So far, their combined effects on terrestrial plants have not been thoroughly investigated....

(This article belongs to the Special Issue Photosynthesis under Biotic and Abiotic Environmental Stress)
  • Article
  • Open Access
5 Citations
4,097 Views
20 Pages

17 September 2021

Melanoma is the most lethal form of skin cancer, which is intrinsically resistant to conventional chemotherapy. Combination therapy has been developed to overcome this challenge and show synergistic anticancer effects on melanoma. Notably, the histon...

(This article belongs to the Special Issue Quo Vadis Cancer Research? On Molecular Mechanisms and Drug Discovery)
  • Article
  • Open Access
713 Views
15 Pages

The Combined Effect of Silver Precursor and Sodium Salt on the Structure and Crystallization Behavior of Photo-Thermo-Refractive Glass

  • Baoxing Xiong,
  • Ziyi Ge,
  • Qiannan Li,
  • Hailong Wang and ,
  • Cunding Liu,
  • Xiao Yuan and
  • Xiang Zhang
  • + 2 authors+ 0 author

Photo-thermo-refractive (PTR) glass is a key material for optical devices, yet the synergistic mechanism between its raw material precursors remains unclear. This study systematically investigates the individual and combined effects of silver precurs...

(This article belongs to the Section Inorganic Chemistry)
  • Article
  • Open Access
33 Citations
5,907 Views
18 Pages

5 January 2018

A thermodynamic model of a thermoelectric generator-driven thermoelectric heat pump (TEG-TEH) combined device is established considering the Thomson effect and the temperature dependence of the thermoelectric properties based on non-equilibrium therm...

(This article belongs to the Section Thermodynamics)
  • Article
  • Open Access
3 Citations
3,790 Views
16 Pages

8 July 2022

An experimental bench was constructed for liquid nitrogen spray cooling in an open loop system, and the combined effect of the spray height, heat sink surface diameter, and spray mass flow on the heat transfer characteristics of liquid nitrogen spray...

  • Review
  • Open Access
144 Citations
22,067 Views
30 Pages

19 June 2021

Association between short-term exposure to ambient air pollution and respiratory health is well documented. At the same time, it is widely known that extreme weather events intrinsically exacerbate air pollution impact. Particularly, hot weather and...

(This article belongs to the Special Issue Challenges in Measuring and Assessing Environmental Health)
  • Article
  • Open Access
1,112 Views
10 Pages

24 June 2025

In the current study, the combined effects of essential oils (EOs) and polyphenols (PPs) were investigated as potential antibiotic alternatives. Thymol and carvacrol at a ratio of 1:1 was used as the EO due to their well-proven synergistic antimicrob...

(This article belongs to the Special Issue Phytochemicals: Extraction, Optimization, Identification, Biological Activities, and Applications in the Food, Nutraceutical, and Pharmaceutical Industries (2nd Edition))
  • Review
  • Open Access
39 Citations
5,925 Views
19 Pages

With the rapid growth of populations worldwide, air quality has become an increasingly important issue related to the health and safety of city inhabitants. There are quite a few factors that contribute to urban air pollution; the majority of studies...

(This article belongs to the Special Issue Environmental Sciences and Engineering: A Look at the Surrounding Environment or Environment and Engineering for a Sustainable Future)
  • Article
  • Open Access
55 Citations
5,776 Views
14 Pages

Influence of Combined Effect of Ultra-Sonication and High-Voltage Cold Plasma Treatment on Quality Parameters of Carrot Juice

  • Muhammad Umair,
  • Saqib Jabbar,
  • Ahmed M. Senan,
  • Tayyaba Sultana and ,
  • Mustapha M. Nasiru,
  • Assar A Shah,
  • Hong Zhuang and
  • Zhang Jianhao
  • + 3 authors+ 0 author

19 November 2019

Influence of the combined effect of ultra-sonication (US) and high-voltage cold plasma treatment (HVCP) on the quality parameters of fresh carrot juice has been studied. During the treatment of ultra-sonication, carrot juice was subjected to a 0.5 in...

  • Review
  • Open Access
19 Citations
7,186 Views
30 Pages

7 July 2024

Weather-related events are among the major causes of failure propagation in natural gas pipeline infrastructure. The interaction between multiple natural-force factors, such as temperature, precipitation, and wind, and their unpredictable simultaneou...

(This article belongs to the Section Sustainable Engineering and Science)
  • Article
  • Open Access
20 Citations
3,913 Views
14 Pages

13 March 2023

Ta hard coatings were prepared on PCrNi1MoA steel substrates by direct current magnetron sputtering, and their growth and phase evolution could be controlled by adjusting the substrate temperature (Tsub) and sputtering power (Pspu) at various conditi...

(This article belongs to the Topic Microstructure and Properties in Metals and Alloys)
  • Communication
  • Open Access
10 Citations
3,258 Views
10 Pages

Combined Displacement and Angle Sensor with Ultra-High Compactness Based on Self-Imaging Effect of Optical Microgratings

  • Mengdi Zhang,
  • Hao Yang,
  • Qianqi Niu,
  • Xuye Zhang and ,
  • Jiaan Yang,
  • Jiangbei Lai,
  • Changjiang Fan,
  • Mengwei Li and
  • Chenguang Xin
  • + 4 authors+ 0 author

30 January 2024

In this paper, an ultracompact combined sensor for displacement and angle-synchronous measurement is proposed based on the self-imaging effect of optical microgratings. Using a two-grating structure, linear and angular displacement can be measured by...

(This article belongs to the Special Issue Imaging and Sensing in Optics and Photonics)
  • Article
  • Open Access
20 Citations
7,514 Views
15 Pages

23 November 2016

The intracellular calcium dynamics in vascular endothelial cells (VECs) in response to wall shear stress (WSS) and/or adenosine triphosphate (ATP) have been commonly regarded as an important factor in regulating VEC function and behavior including pr...

(This article belongs to the Special Issue Insights and Advancements in Microfluidics)
  • Article
  • Open Access
179 Citations
4,974 Views
29 Pages

27 September 2020

Integrated biomass gasification combined cycles can be advantageous for providing multiple products simultaneously. A new electricity and freshwater generation system is proposed based on the integrated gasification and gas turbine cycle as the main...

  • Article
  • Open Access
10 Citations
4,040 Views
8 Pages

Proportion and Number of Upper-Extremity Musculoskeletal Disorders Attributable to the Combined Effect of Biomechanical and Psychosocial Risk Factors in a Working Population

  • Aboubakari Nambiema,
  • Julie Bodin,
  • Susan Stock,
  • Agnès Aublet-Cuvelier and ,
  • Alexis Descatha,
  • Bradley Evanoff and
  • Yves Roquelaure
  • + 2 authors+ 0 author

The objective of this paper is to assess the combined effect of occupational biomechanical and psychosocial risk factors on the incidence of work-related upper-extremity musculoskeletal disorders (UEMSDs) and estimate the proportion and number of inc...

(This article belongs to the Special Issue Prevention of Occupational Risks)
  • Article
  • Open Access
2 Citations
1,888 Views
18 Pages

Assessing the Relative and Combined Effect of Climate and Land Use on Water-Related Ecosystem Services in the Yangtze River Economic Belt, China

  • Yifan Wu,
  • Minglei Yao,
  • Yangbo Tang,
  • Wei Li and ,
  • Tao Yu,
  • Wenlue Ma and
  • Xiaojun Geng
  • + 2 authors+ 0 author

26 July 2024

The ecosystem service (ES) is essential for residents’ health and well-being. The ecosystem service value (ESV) is one of the measures to scientifically quantify the wealth of ESs. However, climate and human activities intensely affect the sust...

(This article belongs to the Section Water Resources Management, Policy and Governance)
  • Proceeding Paper
  • Open Access
1 Citations
2,461 Views
6 Pages

The bridges will be in service in a complex environment for over 100 years under the increasing traffic loading. So the long-term performance determines their safety and durability. Limited by the test condition and ability, present researches are mo...

(This article belongs to the Proceedings of The 18th International Conference on Experimental Mechanics)
  • Article
  • Open Access
50 Citations
7,121 Views
17 Pages

16 May 2021

Onion thrips, Thrips tabaci Lindeman (Thysanoptera: Thripidae) is one of the most damaging insect pests of onions, Allium cepa L., which is an economically important agricultural crop cultivated worldwide. In this study, the combined application of e...

(This article belongs to the Collection Integrated Pest Management in Arable and Open Field Horticultural Crops)
  • Article
  • Open Access
2 Citations
3,054 Views
15 Pages

8 December 2020

Under the action of the same wind azimuth, the extreme values of the wind load effect components of building structures are generated in the along-wind, cross-wind, vertical, and torsional directions. In designing the wind-resistant structure, the ex...

(This article belongs to the Section Civil Engineering)
  • Article
  • Open Access
7 Citations
3,017 Views
12 Pages

Combination therapies appear to be beneficial for preventing bacterial resistance to antibacterial approaches. The aim of this study was to define and determine an optimal effective concentration combination (OPECC) for binary application of antibact...

(This article belongs to the Special Issue Antimicrobial Testing (AMT) 2.0)
  • Article
  • Open Access
32 Citations
8,600 Views
12 Pages

16 March 2015

In this study, type I collagen was coated onto unmodified and modified microporous biphasic calcium phosphate (BCP) scaffolds. Surface characterization using a scanning electron microscope (SEM) and a surface goniometer confirmed the modification of...

(This article belongs to the Special Issue Dental Materials)
  • Article
  • Open Access
1,099 Views
15 Pages

Combined Immune-Stimulatory Effects of HemoHIM and Hwaljingigo Treatment in RAW 264.7 Macrophages

  • Min-Hye Kim,
  • Ji-Hyun Im,
  • Xiaolu Fu,
  • June-Seok Lim and ,
  • Jewon Park,
  • MinWoo Baek,
  • Sun-Il Choi,
  • Do Sang Lee,
  • Im-Joung La and
  • Ok-Hwan Lee
  • + 5 authors+ 0 author

23 April 2026

The immune system plays a pivotal role in the maintenance of homeostasis and protection from pathogens. With increasing public interest in immune health, functional foods and herbal formulations are gaining attention as potential immunomodulators. Th...

  • Article
  • Open Access
32 Citations
3,699 Views
13 Pages

Toxic Effects of Bisphenol A and Bisphenol S on Chlorella Pyrenoidosa under Single and Combined Action

  • Junrong Li,
  • Yingjun Wang,
  • Na Li,
  • Yan He and ,
  • Hong Xiao,
  • Dexin Fang and
  • Chao Chen
  • + 2 authors+ 0 author

Bisphenol A (BPA) is an important industrial chemical; bisphenol S (BPS) is a substitute for BPA. Both are frequently detected in rivers, sewage, and surface water, and have a great impact on the water environment. The effects of BPA and BPS on cell...

(This article belongs to the Topic Emerging Contaminants in the Aquatic Environment)
  • Article
  • Open Access
25 Citations
4,445 Views
14 Pages

Prebiotic Combinations Effects on the Colonization of Staphylococcal Skin Strains

  • Silvia Di Lodovico,
  • Franco Gasparri,
  • Emanuela Di Campli,
  • Paola Di Fermo and ,
  • Simonetta D’Ercole,
  • Luigina Cellini and
  • Mara Di Giulio
  • + 2 authors+ 0 author

Background: An unbalanced skin microbiota due to an increase in pathogenic vs. commensal bacteria can be efficiently tackled by using prebiotics. The aim of this work was to identify novel prebiotic combinations by exerting species-specific action be...

(This article belongs to the Section Medical Microbiology)
  • Article
  • Open Access
5 Citations
5,637 Views
12 Pages

3 September 2019

Gemcitabine (GEM) and cisplatin (CDDP) combination therapy (GC) is the standard chemotherapy for advanced biliary tract cancer (BTC); however, its pharmacotherapeutic efficacy remains unclear. To investigate the effects of GC, we selected 11 from 17...

(This article belongs to the Special Issue Patient-Derived Cancer Models from Basic Study to Clinical Application)
  • Article
  • Open Access
12 Citations
4,332 Views
20 Pages

Mechanical Properties and Cushioning Effectiveness of FPUF-EPS Combination Materials

  • Zexiong Zhang,
  • Weizhou Zhong,
  • Jiaxing Li and
  • Jingrun Luo

27 October 2023

Based on flexible polyurethane foam (FPUF), which is reversible after compression, and expanded polystyrene foam (EPS), which has a high cushioning energy absorption capacity, the parallel and series combinations of FPUF and EPS are provided. Accordi...

  • Article
  • Open Access
58 Citations
7,048 Views
18 Pages

Diosmetin Exerts Synergistic Effects in Combination with 5-Fluorouracil in Colorectal Cancer Cells

  • Sareh Kamran,
  • Ajantha Sinniah,
  • Zamri Chik and
  • Mohammed Abdullah Alshawsh

5-Fluorouracil (5-FU) is a chemotherapeutic medication commonly used to treat colorectal cancer (CRC); however, the drug-associated adverse effects and toxicity have greatly affected its clinical use. Exploring another therapeutic strategy that lower...

(This article belongs to the Special Issue Selected Papers in the 1st International Electronic Conference on Biomedicine (ECB 2021))
  • Article
  • Open Access
30 Citations
5,026 Views
19 Pages

Individual and Combined In Vitro Effects of Deoxynivalenol and Zearalenone on Boar Semen

  • Panagiotis D. Tassis,
  • Ioannis A. Tsakmakidis,
  • Veronika Nagl,
  • Nicole Reisinger and ,
  • Eleni Tzika,
  • Christiane Gruber-Dorninger,
  • Ilias Michos,
  • Nikolaos Mittas,
  • Athina Basioura and
  • Dian Schatzmayr
  • + 5 authors+ 0 author

1 August 2020

Mycotoxins deoxynivalenol (DON) and zearalenone (ZEN) can negatively affect pig health. However, little is known about their effects on boar semen. We assessed the individual and combined effects of DON and ZEN on boar semen in vitro. In a pretrial,...

(This article belongs to the Special Issue Toxic Effect of Mycotoxins)
  • Article
  • Open Access
19 Citations
4,694 Views
13 Pages

14 December 2017

The growth and survival of cancer cells are greatly related to their surrounding microenvironment. To understand the regulation under the impact of anti-cancer drugs and their synergistic effects, we have developed a multiscale agent-based model that...

(This article belongs to the Special Issue Selected Papers from the Second CCF Bioinformatics Conference (CBC 2017))
  • Review
  • Open Access
419 Citations
15,703 Views
23 Pages

Interactions between Medical Plant-Derived Bioactive Compounds: Focus on Antimicrobial Combination Effects

  • Natalia Vaou,
  • Elisavet Stavropoulou,
  • Chrysoula (Chrysa) Voidarou,
  • Zacharias Tsakris and ,
  • Georgios Rozos,
  • Christina Tsigalou and
  • Eugenia Bezirtzoglou
  • + 2 authors+ 0 author

It is accepted that the medicinal use of complex mixtures of plant-derived bioactive compounds is more effective than purified bioactive compounds due to beneficial combination interactions. However, synergy and antagonism are very difficult to study...

(This article belongs to the Special Issue Antimicrobial Activity of Plant-Derived Products and Synthetic Derivatives)
  • Article
  • Open Access
4 Citations
2,726 Views
14 Pages

Effects of Nisin A Combined with Antifungal Drug Against Growth of Candida Species

  • Yoshie Niitani,
  • Kouji Ohta,
  • Kanako Yano,
  • Yoshino Kaneyasu and ,
  • Tomoko Maehara,
  • Honami Kitasaki,
  • Hideo Shigeishi,
  • Hiromi Nishi,
  • Rumi Nishimura and
  • Toshinobu Takemoto
  • + 9 authors+ 4 authors

8 April 2025

Background/Objectives: Nisin A, an antimicrobial peptide produced by Lactococcus lactis, primarily shows antimicrobial activity against Gram-positive bacteria, with efficacy increased when used in combination with an antimicrobial drug. On the other...

  • Article
  • Open Access
2 Citations
2,250 Views
19 Pages

Study on the Sand Reduction Effect of Slope Vegetation Combination in Loess Areas

  • Fucui Wang,
  • Hu Tao,
  • Xi Shi,
  • Shilong Bu and ,
  • Ziming Bao and
  • Dezhi Zhang
  • + 1 author+ 0 author

21 October 2024

Slope erosion in the Loess Plateau region has long been a concern, and vegetation plays an important role in slowing down erosion and controlling sedimentation. However, a single vegetation model shows some limitations when facing complex natural con...

  • Article
  • Open Access
8 Citations
3,551 Views
19 Pages

Numerical Study on Pile Group Effect and Carrying Capacity of Four-Barreled Suction Pile Foundation under V-H-M Combined Loading Conditions

  • Zhen Qi,
  • Tongzhong Wei,
  • Changtao Wang,
  • Fengyun Wang and ,
  • Yin Wang,
  • Jianghong Wang and
  • Juan Li
  • + 2 authors+ 0 author

20 November 2022

Multi-barreled composite foundations are generally used in offshore oil platform structure. However, there is still a lack of theoretical analyses and experimental research. This paper presents the results of a three-dimensional finite element analys...

(This article belongs to the Special Issue Advances in Numerical Modeling for Deep Water Geo-Environment)
  • Review
  • Open Access
537 Citations
24,068 Views
36 Pages

Natural Co-Occurrence of Mycotoxins in Foods and Feeds and Their in vitro Combined Toxicological Effects

  • Marie-Caroline Smith,
  • Stéphanie Madec,
  • Emmanuel Coton and
  • Nolwenn Hymery

26 March 2016

Some foods and feeds are often contaminated by numerous mycotoxins, but most studies have focused on the occurrence and toxicology of a single mycotoxin. Regulations throughout the world do not consider the combined effects of mycotoxins. However, se...

(This article belongs to the Collection Fusarium Toxins – Relevance for Human and Animal Health)
  • Article
  • Open Access
2 Citations
1,607 Views
14 Pages

A Study on the Plugging Effect of Different Plugging Agent Combinations during CO2 Flooding in Heterogeneous Reservoirs

  • Xuetong Zhang,
  • Wenjuan Ji,
  • Haiyang Yu,
  • Yilin Li and ,
  • Fei Yan,
  • Weiqiang Song,
  • Xinrui Jiang and
  • Hongbao Wang
  • + 3 authors+ 0 author

23 May 2024

Gas channeling control is key to improving CO2-flooding efficiency. A traditional plugging system has disadvantages, such as poor adaptability and stability, leading to the poor plugging effect of CO2 channeling in heterogeneous reservoirs and diffic...

(This article belongs to the Section H: Geo-Energy)
  • Article
  • Open Access
27 Citations
7,419 Views
15 Pages

The xenoestrogens nonylphenol (NP) and bisphenol A (BPA) are regarded as endocrine disrupting chemicals (EDCs) which have widespread occurrence in our daily life. In the present study, the purpose was to analyze the combined effects of NP and BPA on...

  • Article
  • Open Access
14 Citations
8,001 Views
10 Pages

12 March 2021

To evaluate the combination effects of anti-onychomycosis drugs, the minimum inhibitory concentrations of topical (efinaconazole, luliconazole, and tavaborole) and oral (itraconazole and terbinafine) drugs for Trichophyton rubrum and Trichophyton int...

  • Article
  • Open Access
2 Citations
1,448 Views
16 Pages

Background/Objectives: Multidrug-resistant (MDR) strains of Streptococcus suis are increasingly prevalent and present significant challenges in clinical management. Given that the development of new antibiotics is a resource-intensive process and tim...

  • Review
  • Open Access
8 Citations
7,695 Views
62 Pages

Combined Radiations: Biological Effects of Mixed Exposures Across the Radiation Spectrum

  • Orfeas Parousis-Paraskevas,
  • Angeliki Gkikoudi,
  • Amer Al-Qaaod,
  • Spyridon N. Vasilopoulos and ,
  • Gina Manda,
  • Christina Beinke,
  • Siamak Haghdoost,
  • Georgia I. Terzoudi,
  • Faton Krasniqi and
  • Alexandros G. Georgakilas
  • + 5 authors+ 0 author

5 September 2025

Combined radiation exposures—pairings of ionizing and non-ionizing radiation—are increasingly relevant in medical, spaceflight, and environmental contexts. This systematic review evaluates their radiobiological effects and therapeutic app...

(This article belongs to the Section Molecular Biology)
  • Article
  • Open Access
8 Citations
4,329 Views
18 Pages

Evaluation of Additive Neuroprotective Effect of Combination Therapy for Parkinson’s Disease Using In Vitro Models

  • Alexander Shtilbans,
  • Elise Esneault,
  • Florian Simon,
  • Joseph R. Mazzulli and ,
  • Drew J. Quiriconi,
  • Dror Rom,
  • Wolfgang E. Reintsch,
  • Andrea I. Krahn and
  • Thomas M. Durcan
  • + 4 authors+ 0 author

Background: All the processes leading to neurodegeneration cannot be addressed with just one medication. Combinations of drugs affecting various disease mechanisms concurrently could demonstrate improved effect in slowing the course of Parkinson&rsqu...

(This article belongs to the Special Issue Oxidative Stress Mechanisms and Parkinson's Disease Treatment)
  • Article
  • Open Access
7 Citations
3,868 Views
19 Pages

Combination of Talazoparib and Calcitriol Enhanced Anticancer Effect in Triple−Negative Breast Cancer Cell Lines

  • Fu Hou Wong,
  • Vijayaraj Kumar Palanirajan,
  • Edmond Siah Chye Ng,
  • Chung Keat Tan and ,
  • Eugenie Sin Sing Tan and
  • Farahnaz Amini
  • + 1 author+ 0 author

29 August 2022

Monotherapy for triple−negative breast cancer (TNBC) is often ineffective. This study aimed to investigate the effect of calcitriol and talazoparib combination on cell proliferation, migration, apoptosis and cell cycle in TNBC cell lines. Monot...

(This article belongs to the Section Pharmacology)
  • Article
  • Open Access
7 Citations
4,635 Views
20 Pages

CC(U)S Initiatives: Public Effects and “Combined Value” Performance

  • Alina Ilinova,
  • Natalia Romasheva and
  • Alexey Cherepovitsyn

The changes in climate, which are associated with the emission of anthropogenic greenhouse gases, have been widely discussed by scientists and specialists during the last few decades. The promising way to reduce CO2 emission is to implement CC(U)S te...

(This article belongs to the Special Issue Renewables Application: Challenges and Perspectives)
  • Article
  • Open Access
30 Citations
4,541 Views
15 Pages

In Vitro Evaluation of the Individual and Combined Cytotoxic and Estrogenic Effects of Zearalenone, Its Reduced Metabolites, Alternariol, and Genistein

  • Adrienn Balázs,
  • Zelma Faisal,
  • Rita Csepregi,
  • Tamás Kőszegi and ,
  • Balázs Kriszt,
  • István Szabó and
  • Miklós Poór
  • + 2 authors+ 0 author

Mycotoxins are toxic metabolites of filamentous fungi. Previous studies demonstrated the co-occurrence of Fusarium and Alternaria toxins, including zearalenone (ZEN), ZEN metabolites, and alternariol (AOH). These xenoestrogenic mycotoxins appear in s...

(This article belongs to the Collection Feature Papers in Molecular Toxicology)
  • Article
  • Open Access
20 Citations
4,073 Views
23 Pages

Suppression of Tumor Growth and Cell Migration by Indole-Based Benzenesulfonamides and Their Synergistic Effects in Combination with Doxorubicin

  • Phuong Linh Nguyen,
  • Ahmed Elkamhawy,
  • Young Hee Choi,
  • Chang Hoon Lee and ,
  • Kyeong Lee and
  • Jungsook Cho
  • + 1 author+ 0 author

31 August 2022

Pharmacological inhibition of the enzyme activity targeting carbonic anhydrases (CAs) demonstrated antiglaucoma and anticancer effects through pH control. Recently, we reported a series of indole-based benzenesulfonamides as potent CA inhibitors. The...

(This article belongs to the Special Issue Novel Therapeutic Strategies for Cancer)

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