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Article

13 Citations

6,639 Views

13 Pages

Characterization of Different Types of Excitability in Large Somatosensory Neurons and Its Plastic Changes in Pathological Pain States

Rou-Gang Xie,
Wen-Guang Chu,
San-Jue Hu and
Ceng Luo

Int. J. Mol. Sci.2018, 19(1), 161;https://doi.org/10.3390/ijms19010161

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5 January 2018

Sensory neuron types have been distinguished by distinct morphological and transcriptional characteristics. Excitability is the most fundamental functional feature of neurons. Mathematical models described by Hodgkin have revealed three types of neur...

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Article

7 Citations

4,663 Views

13 Pages

Differential Activation of pERK1/2 and c-Fos Following Injury to Different Regions of Primary Sensory Neuron

Bei Miao,
Hongyu Yao,
Peng Chen and
Xue-Jun Song

Life2022, 12(5), 752;https://doi.org/10.3390/life12050752

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19 May 2022

Nerve injury causes hyperexcitability of the dorsal root ganglion (DRG) and spinal dorsal horn (DH) neurons, which results in neuropathic pain. We have previously demonstrated that partial dorsal rhizotomy (PDR) produced less severe pain-like behavio...

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