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Article

26 Citations

6,622 Views

15 Pages

Curcumin Supplementation Ameliorates Bile Cholesterol Supersaturation in Hamsters by Modulating Gut Microbiota and Cholesterol Absorption

Ting Hong,
Jun Zou,
Xin Jiang,
Jie Yang,
Zhuo Cao,
Youming He and
Dan Feng

Nutrients2022, 14(9), 1828;https://doi.org/10.3390/nu14091828

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27 April 2022

Curcumin is a polyphenol that has been shown to have prebiotic and cholesterol-lowering properties. This study aimed to investigate the impact of curcumin on bile cholesterol supersaturation and the potential mechanistic role of intestinal microbiota...

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Review

134 Citations

27,587 Views

13 Pages

Factors Influencing Gallstone Formation: A Review of the Literature

Hao Sun,
Jonathan Warren,
James Yip,
Yu Ji,
Shaolong Hao,
Wei Han and
Yuchuan Ding

Biomolecules2022, 12(4), 550;https://doi.org/10.3390/biom12040550

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6 April 2022

Gallstone disease is a common pathology of the digestive system with nearly a 10–20% incidence rate among adults. The mainstay of treatment is cholecystectomy, which is commonly associated with physical pain and may also seriously affect a pati...

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Review

23 Citations

7,489 Views

25 Pages

Genetic Analysis of ABCB4 Mutations and Variants Related to the Pathogenesis and Pathophysiology of Low Phospholipid-Associated Cholelithiasis

Helen H. Wang,
Piero Portincasa,
Min Liu and
David Q.-H. Wang

Genes2022, 13(6), 1047;https://doi.org/10.3390/genes13061047

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11 June 2022

Clinical studies have revealed that the ABCB4 gene encodes the phospholipid transporter on the canalicular membrane of hepatocytes, and its mutations and variants are the genetic basis of low phospholipid-associated cholelithiasis (LPAC), a rare type...

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