Search Results (20)

Environmental monitoring across extensive regions is often constrained by the high costs of conventional laboratory analysis. This study proposes a methodology for electrophysiological characterization of Aloe vera as a potential biological dosimeter for low-cost environmental sensing. Using an ATMega328P-based acquisition system with high-input-impedance signal conditioning, we recorded plant biopotentials under controlled abiotic stressors. Signal variations were evaluated as a function of leaf morphology, electrode placement, and environmental variables, including light intensity, soil moisture, water saturation, and pH. The statistical validation included Jaccard similarity coefficients for repeatability and Kruskal–Wallis tests for group comparisons. The measurements showed highly repeatable baseline behavior (Jaccard similarity in the range 0.95–0.99) and significant differences across stress conditions, particularly under changes in light intensity. These findings support the feasibility of using Aloe vera electrophysiological signals as a robust and low-cost basis for developing plant-based biosensing approaches in environmental monitoring applications. Full article

This work presents the development and characterization of a flexible capacitive electrode for non-contact ECG acquisition, fabricated using a simple and cost-effective method from readily available materials. The electrode consists of a multilayer structure with a copper conductor laminated by a polyimide (Kapton^®) dielectric layer on a polyurethane support. The impedance and capacitance of the electrode were evaluated under varying textile moisture levels with artificial sweat, as well as after exposure to common disinfectants including ethyl alcohol and iodine tincture. Electrochemical impedance spectroscopy (EIS) and broadband impedance measurements (10⁻¹–10⁵ Hz) confirmed stable capacitive behavior, moderate sensitivity to moisture, and chemical stability of the Kapton–copper interface under conditions simulating repeated use. A custom front-end readout circuit was implemented to demonstrate through-textile ECG signal acquisition. Simulator tests reproduced characteristic waveform patterns, and preliminary volunteer recordings confirmed the feasibility of through-textile acquisition. These results highlight the promise of the electrode as a low-cost platform for future wearable biosignal monitoring technical research. Full article

This study aimed to investigate the degradation of dry biopotential electrodes using the anodic stripping voltammetry (ASV) technique. The electrodes were based on Ti-Cu thin films deposited on different polymeric substrates (polyurethane, polylactic acid, and cellulose) by Direct Current (DC) magnetron sputtering. TiCu_0.34 thin films (chemical composition of 25.4 at.% Cu and 74.6 at.% Ti) were prepared by sputtering a composite Ti target. For comparison purposes, a Cu-pure thin film was prepared under the same conditions and used as a reference. Both films exhibited dense microstructures with differences in surface topography and crystalline structure. The degradation process involved immersing TiCu_0.34 and Cu-pure thin films in artificial sweat (prepared following the ISO standard 3160-2) for different durations (1 h, 4 h, 24 h, 168 h, and 240 h). ASV was the technique selected to quantify the amount of Cu(II) released by the electrodes immersed in the sweat solution. The optimal analysis conditions were set for 120 s and −1.0 V for time deposition and potential deposition, respectively, with a quantification limit of 0.050 ppm and a detection limit of 0.016 ppm. The results showed that TiCu_0.34 electrodes on polyurethane substrates were significantly more reliable over time compared to Cu-pure electrodes. After 240 h of immersion, the TiCu_0.34 electrodes released a maximum of 0.06 ppm Cu, while Cu-pure electrodes released 16 ppm. The results showed the significant impact of the substrate on the electrode’s longevity, with cellulose bases performing poorly. TiCu_0.34 thin films on cellulose released 1.15 µg/cm² of copper after 240 h, compared to 1.12 mg/cm² from Cu-pure films deposited on the same substrate. Optical microscopy revealed that electrodes based on polylactic acid substrates were more prone to corrosion over time, whereas TiCu thin-film metallic glass-like structures on PU substrates showed extended lifespan. This study underscored the importance of assessing the degradation of dry biopotential electrodes for e-health applications, contributing to developing more durable and reliable sensing devices. While the study simulated real-world conditions using artificial sweat, it did not involve in vivo measurements. Full article

Functional electrical stimulation (FES) is a rehabilitation and assistive technique used for stroke survivors. FES systems mainly consist of sensors, a control algorithm, and a stimulation unit. However, there is a critical need to reassess sensing and control techniques in FES systems to enhance their efficiency. This SLR was carried out following the PRISMA 2020 statement. Four databases (PubMed, Scopus, Web of Science, Wiley Online Library) from 2010 to 2024 were searched using terms related to sensing and control strategies in FES systems. A total of 322 articles were chosen in the first stage, while only 60 of them remained after the final filtering stage. This systematic review mainly focused on sensor techniques and control strategies to deliver FES. The most commonly used sensors reported were inertial measurement units (IMUs), 45% (27); biopotential electrodes, 36.7% (22); vision-based systems, 18.3% (11); and switches, 18.3% (11). The control strategy most reported is closed-loop; however, most of the current commercial FES systems employ open-loop strategies due to their simplicity. Three main factors were identified that should be considered when choosing a sensor for gait-oriented FES systems: wearability, accuracy, and affordability. We believe that the combination of computer vision systems with artificial intelligence-based control algorithms can contribute to the development of minimally invasive and personalized FES systems for the gait rehabilitation of patients with FDS. Full article

We propose a new methodology for long-term biopotential recording based on an MEMS multisensor integrated platform featuring a commercial electrostatic charge-transfer sensor. This family of sensors was originally intended for presence tracking in the automotive industry, so the existing setup was engineered for the acquisition of electrocardiograms, electroencephalograms, electrooculograms, and electromyography, designing a dedicated front-end and writing proper firmware for the specific application. Systematic tests on controls and nocturnal acquisitions from patients in a domestic environment will be discussed in detail. The excellent results indicate that this technology can provide a low-power, unexplored solution to biopotential acquisition. The technological breakthrough is in that it enables adding this type of functionality to existing MEMS boards at near-zero additional power consumption. For these reasons, it opens up additional possibilities for wearable sensors and strengthens the role of MEMS technology in medical wearables for the long-term synchronous acquisition of a wide range of signals. Full article

Wireless sensing systems are required for continuous health monitoring and data collection. It allows for patient data collection in real time rather than through time-consuming and expensive hospital or lab visits. This technology employs wearable sensors, signal processing, and wireless data transfer to remotely monitor patients’ health. The research offers a novel approach to providing primary diagnostics remotely with a digital health system for monitoring pulmonary health status using a multimodal wireless sensor device. The technology uses a compact wearable with new integration of acoustics and biopotentials sensors to monitor cardiovascular and respiratory activity to provide comprehensive and fast health status monitoring. Furthermore, the small wearable sensor size may stick to human skin and record heart and lung activities to monitor respiratory health. This paper proposes a sensor data fusion method of lung sounds and cardiograms for potential real-time respiration pattern diagnostics, including respiratory episodes like low tidal volume and coughing. With a p-value of 0.003 for sound signals and 0.004 for electrocardiogram (ECG), preliminary tests demonstrated that it was possible to detect shallow breathing and coughing at a meaningful level. Full article

This paper presents a 12-b successive approximation register (SAR) analog-to-digital converter (ADC) for biopotential sensing applications. To reduce the digital-to-analog converter (DAC) switching energy of the high-resolution ADC, we combine merged-capacitor-switching (MCS) and detect-and-skip (DAS) methods, successfully embedded in the subranging structure. The proposed method saves 96.7% of switching energy compared to the conventional method. Without an extra burden on the realization of the calibration circuit, we achieve mismatch calibration by reusing the on-chip DAC. The mismatch data are processed in the digital domain to compensate for the nonlinearity caused by the DAC mismatch. The ADC is realized using a 0.18 μm CMOS process with a core area of 0.7 mm². At the sampling rate f_S = 9 kS/s, the ADC achieves a signal-to-noise ratio and distortion (SINAD) of 67.4 dB. The proposed calibration technique improves the spurious-free dynamic range (SFDR) by 7.2 dB, resulting in 73.5 dB. At an increased f_S = 200 kS/s, the ADC achieves a SINAD of 65.9 dB and an SFDR of 68.8 dB with a figure-of-merit (FoM) of 13.2 fJ/conversion-step. Full article

In this paper, a low-power and low-noise capacitive-coupled chopper instrumentation amplifier (CCIA) is proposed for biopotential sensing applications. A chopping technique is applied to mitigate the domination of flicker noise at low frequency. A new offset cancellation loop is also used to deal with the intrinsic offset, originating from process variation, to reduce ripple noise at the output of CCIA. Moreover, the optimization of the chip area was resolved by adding a T-network capacitor in the negative feedback loop. The CCIA is designed on 0.18 µm process CMOS technology with a total chip area of 0.09 mm². The post-simulation results show that the proposed architecture can attenuate the output ripple up to 41 dB with a closed-loop gain of 40 dB and up to 800 Hz of bandwidth. The integrated input referred noise (IRN) of the CCIA is 1.8 µV_rms over a bandwidth of 200 Hz. A noise efficiency factor (NEF) of 5.4 is obtained with a total power dissipation of 1.2 µW and a supply voltage of 1 V, corresponding to a power efficiency factor of 9.7 that is comparable with that of state-of-the-art studies. Full article

In a new era for digital health, dry electrodes for biopotential measurement enable the monitoring of essential vital functions outside of specialized healthcare centers. In this paper, a new type of nanostructured titanium-based thin film is proposed, revealing improved biopotential sensing performance and overcoming several of the limitations of conventional gel-based electrodes such as reusability, durability, biocompatibility, and comfort. The thin films were deposited on stainless steel (SS) discs and polyurethane (PU) substrates to be used as dry electrodes, for non-invasive monitoring of body surface biopotentials. Four different Ti–Me (Me = Al, Cu, Ag, or Au) metallic binary systems were prepared by magnetron sputtering. The morphology of the resulting Ti–Me systems was found to be dependent on the chemical composition of the films, specifically on the type and amount of Me. The existence of crystalline intermetallic phases or glassy amorphous structures also revealed a strong influence on the morphological features developed by the different systems. The electrodes were tested in an in-vivo study on 20 volunteers during sports activity, allowing study of the application-specific characteristics of the dry electrodes, based on Ti–Me intermetallic thin films, and evaluation of the impact of the electrode–skin impedance on biopotential sensing. The electrode–skin impedance results support the reusability and the high degree of reliability of the Ti–Me dry electrodes. The Ti–Al films revealed the least performance as biopotential electrodes, while the Ti–Au system provided excellent results very close to the Ag/AgCl reference electrodes. Full article

The idea of passive biosensing through inductive coupling between antennas has been of recent interest. Passive sensing systems have the advantages of flexibility, wearability, and unobtrusiveness. However, it is difficult to build such systems having good transmission performance. Moreover, their near-field coupling makes them sensitive to misalignment and movements. In this work, to enhance transmission between two antennas, we investigate the effect of superstrates and metamaterials and propose the idea of dielectric fill in between the antenna and the superstrate. Preliminary studies show that the proposed method can increase transmission between a pair of antennas significantly. Specifically, transmission increase of ≈5 dB in free space and ≈8 dB in lossy media have been observed. Next, an analysis on a representative passive neurosensing system with realistic biological tissues shows very low transmission loss, as well as considerably better performance than the state-of-the-art systems. Apart from transmission enhancement, the proposed technique can significantly mitigate performance degradation due to misalignment of the external antenna, which is confirmed through suitable sensitivity analysis. Overall, the proposed idea can have fascinating prospects in the field of biopotential sensing for different biomedical applications. Full article

Cardiovascular diseases (CVDs) have been listed among the most deadly diseases worldwide. Many CVDs are likely to manifest their symptoms some time prior to the onset of any adverse or catastrophic events, and early detection of cardiac abnormalities is incredibly important. However, traditional electrocardiography (ECG) monitoring systems face challenges with respect to their scalability and affordability as they require direct body contact and cumbersome equipment. As a step forward from the large-scale direct-contact ECG monitoring devices, which are inconvenient for the user in terms of wearability and portability, in this research, we present a small-sized, non-contact, real-time recording system for mobile long-term monitoring of ECG signals. The device mainly comprises three non-contact electrodes to sense the bio-potential signal, an AD8233 AFE IC to extract the ECG signal, and a CC2650 MCU to read, filter, and transmit them. The device is powered by a 2000 mAh lithium-ion battery with isolation between digital and analog powers on the board using two low-dropout regulators (LDOs). The board’s dimension is 8.56 cm × 5.4 cm, the size of a credit card, making it optimal to be worn in a shirt chest pocket. In spite of its small form factor, the device still manages to achieve a continuous measurement battery life of over 16 h, total harmonic distortion below −30 dB across the interested frequency range, an input-referred noise as low as 1.46 µV for contacted cases and 5.15 µV for non-contact cases through cotton, and clear ECG recording for both contact and non-contact sensing, all at a cost around USD 50. Full article

Several on-body sensing and communication applications use electrodes in contact with the human body. Body–electrode interfaces in these cases act as a transducer, converting ionic current in the body to electronic current in the sensing and communication circuits and vice versa. An ideal body–electrode interface should have the characteristics of an electrical short, i.e., the transfer of ionic currents and electronic currents across the interface should happen without any hindrance. However, practical body–electrode interfaces often have definite impedances and potentials that hinder the free flow of currents, affecting the application’s performance. Minimizing the impact of body–electrode interfaces on the application’s performance requires one to understand the physics of such interfaces, how it distorts the signals passing through it, and how the interface-induced signal degradations affect the applications. Our work deals with reviewing these elements in the context of biopotential sensing and human body communication. Full article

Biopotential sensing technology with electrodes has a great future in medical treatment and human—machine interface, whereas comfort and longevity are two significant problems during usage. Noncontact electrode is a promising alternative to achieve more comfortable and long term biopotential signal recordings than contact electrode. However, it could pick up a significantly higher level of common-mode (CM) noise, which is hardly solved with passive filtering. The impedance imbalance at the electrode-body interface is a limiting factor of this problem, which reduces the common mode rejection ratio (CMRR) of the amplifier. In this work, we firstly present two novel CM noise reduction circuit designs. The circuit designs are based on electrode-body impedance imbalance cancellation. We perform circuit analysis and circuit simulations to explain the principles of the two circuits, both of which showed effectiveness in CM noise rejection. Secondly, we proposed a practical approach to detect and monitor the electrode-body impedance imbalance change. Compared with the conventional approach, it has certain advantages in interference immunity, and good linearity for capacitance. Lastly, we show experimental evaluation results on one of the designs we proposed. The results indicated the validity and feasibility of the approach. Full article

The subject of the submitted work is the proposal of electrodes for the continual measurement of the glucose concentration for the purpose of specifying further hemodynamic parameters. The proposal includes the design of the electronic measuring system, the construction of the electrodes themselves and the functionality of the entire system, verified experimentally using various electrode materials. The proposed circuit works on the basis of micro-ammeter measuring the size of the flowing electric current and the electrochemical measurement method is used for specifying the glucose concentration. The electrode system is comprised of two electrodes embedded in a silicon tube. The solution consists of the measurement with three types of materials, which are verified by using three solutions with a precisely given concentration of glucose in the form of a mixed solution and enzyme glucose oxidase. For the testing of the proposed circuit and the selection of a suitable material, the testing did not take place on measurements in whole blood. For the construction of the electrodes, the three most frequently used materials for the construction of electrodes used in clinical practice for sensing biopotentials, specifically the materials Ag/AgCl, Cu and Au, were used. The performed experiments showed that the material Ag/AgCl, which had the greatest sensitivity for the measurement even without the enzyme, was the most suitable material for the electrode. This conclusion is supported by the performed statistical analysis. On the basis of the testing, we can come to the conclusion that even if the Ag/AgCl electrode appears to be the most suitable, showing high stability, gold-plated electrodes showed stability throughout the measurement similarly to Ag/AgCl electrodes, but did not achieve the same qualities in sensitivity and readability of the measured results. Full article

This article introduces a two-electrode ground-free electrocardiogram (ECG) with minimal hardware complexity, which is ideal for wearable battery-powered devices. The main issue of ground-free measurements is the presence of noise. Therefore, noise suppression methods that can be employed for a two-electrode ECG acquisition system are discussed in detail. Experimental measurements of a living subject and patient simulator are used to investigate and compare the performance of the three proposed methods utilizing the ADS1191 analogue front-end for biopotential measurements. The resulting signals recorded for the simulator indicate that all three methods should be suitable for suppressing power-line noise. The Power Spectral Density (PSD) of the signals measured for a subject exhibits differences across methods; the signal power at 50 Hz is −28, −24.8, and −26 dB for the first, second, and third method, respectively. The digital postprocessing of measured signals acquired a high-quality ECG signal comparable to that of three-electrode sensing. The current consumption measurements demonstrate that all proposed two-electrode ECG solutions are appropriate as a battery-powered device (current consumption < 1.5 mA; sampling rate of 500 SPS). The first method, according to the results, is considered the most effective method in the suppression of power-line noise, current consumption, and hardware complexity. Full article