Search Results (1,633)

Background/Objectives: Childhood overweight and obesity are influenced by family-level behaviors related to nutrition, physical activity, and daily routines. This study aimed to In contrast to screen time family nutrition and physical activity practices for overweight and obesity among children aged 6–17 years in Türkiye. Methods: A cross-sectional study was conducted with 214 children recruited from a community setting. Sociodemographic data and anthropometric measurements were collected, and family practices were assessed using the Family Nutrition and Physical Activity Scale–Turkish version (FNPA-TR). Binary logistic regression analyses were performed separately for overweight and obesity outcomes. Results: Healthier beverage choices were the only significant predictor of overweight, reducing the odds by 62%. Obesity was predicted by three FNPA domains: family meal frequency, family eating habits, and screen time. Frequent family meals and healthier eating habits were associated with lower obesity risk, whereas higher screen exposure increased the likelihood of obesity. Conclusions: Beverage choices, family meal patterns, eating habits, and screen exposure emerged as key behavioral predictors of unhealthy weight status in children. These findings highlight key family-centered prevention targets for pediatric nursing and public health, including promoting healthy beverage consumption, strengthening structured family eating routines, and reducing screen exposure in children. Full article

The circadian cycle regulates metabolism in response to external stimuli, such as light exposure, sleep schedules, and eating patterns. However, misalignment between internal biological rhythms and social demands can compromise food choices, potentially leading to overweight and obesity. This research aimed to assess how a person’s chronotype links to social jet lag (SJL), which in turn would relate to their nutritional status and food consumption patterns as a university student. 617 students from a State University located in the State of Paraná, Brazil, completed a cross-sectional research study that collected sociodemographic information/anthropometrics by means of an online survey. It included self-reported height/weight data and dietary habits. The Munich Chronotype Questionnaire (MCTQ) was utilized to determine each participant’s chronotype classification and SJL calculation. Researchers found that nearly half of the students (49.3%) displayed an Intermediate Chronotype, which is associated with a diet that contained elements of the “Mixed” Diet, meaning there are equal portions of healthy food (Fresh Fruits, Beans, etc.) and unhealthy foods (Sweetened Beverages). The multivariate logistic regression analyses identified age as a significant predictor of obesity risk (OR: 1.15, p < 0.001), while dietary habits such as fruit consumption played a protective role. Additionally, having a breakfast protected them from being classified as obese compared to those who did not eat breakfast (OR = 0.59). Contrary to expectations, late-night supper was not a statistically significant predictor in the adjusted model. Predictors of an Intermediate chronotype included being male and eating morning snacks regularly. The results of this study suggest that students with an intermediate chronotype will predictably have skewed eating patterns, such as skipping breakfast and eating late—both of which affect obesity risks. Nutritional strategies for university students should focus on promoting circadian regularity and optimizing meal timing. Full article

Beverages, particularly sugar-sweetened beverages (SSBs), pose a significant public health concern globally. Changing eating habits among Pakistani young adults have led to higher sugary drink consumption, underscoring the need for a suitable cultural assessment tool. A cross-sectional study was conducted among 381 university students aged 18–26 years from three major cities of Pakistan. Following World Health Organization (WHO) guidelines, the original Beverage Intake Questionnaire (BEVQ-15) was modified by removing four items (including alcoholic beverages), adding two culturally relevant types (flavored milk and refreshing drinks), and converting measurement units to milliliters, resulting in a 13-item Beverage Intake Questionnaire-Pakistan (BEVQ-PK). Validity was assessed by comparing BEVQ-PK1 (test) with three 24 h dietary recalls. Test–retest reliability was evaluated after a 14-day interval by comparing BEVQ-PK1 (test) and BEVQ-PK2 (retest). Analyses included descriptive statistics, paired sample t-tests, Intraclass Correlation Coefficients (ICC), Bland–Altman plots, and Spearman’s correlations. The BEVQ-PK (13-item) demonstrated moderate to strong validity (r = 0.2–0.8, p < 0.001) and strong reliability (r = 0.5–0.9, p < 0.001). Most beverage categories showed no significant intake differences between test and retest. Tea/coffee with milk was the most frequently consumed beverage, followed by soft drinks and green/black tea. Overall, BEVQ-PK is a valid and reliable tool for assessing SSB intake among Pakistani university students and can support future nutrition and public health research. Full article

Background: Childhood obesity and being overweight represent a global public health challenge; the consumption of sugar-sweetened beverages (SSBs) and ultra-processed foods (UPFs) contributes to this problem. In Mexico, public health policies have been implemented to improve school food environments. Objective: To assess the school food environment before the implementation of the guidelines for the preparation, distribution, and sale of food and beverages (SFGs) in three primary schools in Mexico City. Methods: A cross-sectional mixed method study was conducted, including structured non-participatory observation of selling points outside and inside of schools, and availability of drinking fountains and lunchboxes contents. A food waste audit assessment was performed to identify the most frequently consumed products, main ingredients, front-of-package labels, and colorants. Additionally, 23 semi-structured interviews were conducted with school authorities, teachers, and food vendors. Results: SSBs and UPFs selling points were observed outside and inside in public schools, while in private schools, only inside, with use of delivery food apps. Public schools lacked functional drinking fountains. A total of 345 food waste items were collected across the schools, of which 46.3% were SSBs and 53.7% were UPFs. The main ingredient was sugar (15.6%), the principal front-of-package was excess sugar (37.5%), and the most frequently used colorants were red 40 (25.1%). Interview participants reported awareness of the SFGs; however, they identified barriers such as resistance from parents and students and the economic dependence of school cooperatives on UPFs sales. Conclusions: These findings highlight structural and economic challenges for the effective implementation of public policies promoting healthier school food environments. Full article

Background/Objectives: Alternative Tobacco and Nicotine Products (ATNPs) have gained widespread popularity. Although they are often promoted as lower-risk alternatives to traditional tobacco products, concerns remain regarding their association with risky behaviors among adolescents and young adults. This study examines the relationship between dietary and lifestyle habits and both ATNP use and intention to use ATNP among Italian participants in the MINERVA (My changINg lifEstyles our Research and eVeryone heAlth) international project. Methods: MINERVA is an observational, international, prospective cohort study. A study-specific questionnaire was administered to participants, who were recruited through informal snowball sampling. The questionnaire collected information on sociodemographic characteristics, lifestyle factors, dietary habits, and the use of both traditional tobacco products and ATNPs. Predictors of ATNP use and intention to use were assessed using logistic regression models. Results: Data from 7535 Italian participants were analyzed. Overall, 48% reported having ever used ATNP, and 14% of non-smokers and non-users expressed an intention to try these products. Significant predictors of ATNP use and intention to use included prior smoking, lower age, and having family members who smoke. Lifestyle factors such as frequent consumption of fast food, junk food, and alcoholic beverages were positively associated with both ATNP use and intention to use. Conversely, daily fruit and vegetable consumption was inversely associated with these outcomes. Conclusions: ATNP use and intention to use were associated with unhealthy dietary and lifestyle patterns. These findings highlight the importance of integrated public health strategies addressing substance use alongside broader lifestyle behaviors among adolescents and young adults. Full article

Background: Depression represents a major public health burden in Hungary, where prevalence remains higher than the global average. Although diet is an increasingly studied factor associated with mental health, evidence from Central and Eastern Europe is scarce. Methods: This cross-sectional study analyzed data from the Hungarian wave of the European Health Interview Survey (EHIS) 2019, a nationally representative sample of 5603 adults aged ≥15 years. Depressive symptom severity was assessed using the Patient Health Questionnaire-8 (PHQ-8) and categorized as none (0–4), mild (5–9), and moderate-to-severe (≥10). Self-reported frequency of consumption of fruits, vegetables, fruit juice, dairy products, fish, processed meat, sweetened beverages, coffee, and sweeteners was examined. Multivariable ordinal logistic regression models, adjusted for gender, age, education, income, physical activity, smoking, and alcohol consumption, were used to estimate associations with depressive symptom severity. Results: Overall, 77.9% of participants had no depression, 17.0% mild, and 5.1% moderate-to-severe symptoms. After full adjustment, lower consumption of fruits and vegetables, less frequent fruit juice intake, and lower processed meat consumption were associated with higher odds of more severe depressive symptoms. Moderate coffee intake (1–2 cups/day) was associated with lower odds than heavier consumption. Conclusions: In the Hungarian adult population, poorer dietary patterns, particularly low intake of fruits, vegetables, and paradoxically lower processed meat consumption, are significantly associated with greater depressive symptom severity, independent of major sociodemographic and lifestyle factors. These findings underscore the potential role of diet quality in mental health and support public health efforts to promote nutrient-rich dietary patterns in Hungary. Full article

Background/Objectives: Moderate consumption of fermented beverages such as traditional beer has been associated with antioxidant and anti-inflammatory effects. MicroRNAs (miRNAs) play key roles in inflammation and oxidative stress, yet the impact of moderate fermented beverage consumption on blood miRNA profiles remains poorly understood. This study investigated the effects of regular, moderate intake of traditional and alcohol-free beer on whole blood miRNA levels in healthy adults. Methods: Whole blood samples were collected at baseline and after a 4-week intervention with alcohol-free beer and traditional beer in healthy overweight/obese adults (n = 36). miRNA profiling was performed using Affymetrix in a discovery subset, followed by targeted validation using real-time PCR in the full cohort. Bioinformatics and system biology analysis were applied to explore potential functional associations. Results: After traditional beer consumption, 202 miRNAs showed differential expression compared to baseline (p < 0.05). Eighteen miRNAs with changes ≥1.5-fold and the two miRNAs with the lowest p-values (p < 0.005) were selected for further analysis. Of them, the six miRNAs with the most consistent expression patterns were validated by real-time PCR. Moderate beer intake was associated with increased levels of miR-144-5p and miR-19a-3p in the overall population. Sex-stratified analyses suggested a tendency toward higher levels in these miRNAs in women following traditional beer intake. In silico analysis showed that predicted target genes of these miRNAs are involved in pathways related to immune regulation and inflammatory signaling. Conclusions: Moderate beer consumption is associated with consistent changes in whole-blood miRNA expression, particularly miR-144-5p and miR-19a-3p, in a healthy overweight/obese population. These findings support a potential role for epigenetic modulation in the biological response to moderate beer intake and provide a basis for future mechanistic studies. Full article

Trypanosoma cruzi is the causative agent of Chagas disease, which affects 6–7 million people worldwide. Although the possibility of oral transmission was first scientifically suggested in 1913, it was not until 1968 that the first confirmed cases of human infection via food consumption were reported. This long gap contributed to the widespread perception that oral transmission was a rare or incidental event. Over the past two decades, significant advances have been made in understanding the biological and clinical aspects of oral transmission, including the molecular mechanisms by which metacyclic trypomastigotes establish infection via the digestive route. Experimental studies in murine models have further deepened our knowledge of the biology and pathogenesis of oral infection. Concurrently, multiple outbreaks of T. cruzi infection through contaminated food and beverages have been reported across Latin America, providing valuable insights into the molecular epidemiology and clinical characteristics of this transmission route. Moreover, experimental evidence has shown that the consumption of meat from animals infected during the acute phase can also lead to T. cruzi infection, highlighting carnivory as a potential alternative transmission mechanism. This review aims to comprehensively analyze oral infection by T. cruzi, considering clinical and epidemiological data, parasite biology, and findings from murine experimental models. Strategies for controlling foodborne transmission of Chagas disease are also discussed. Full article

Alcohol consumption is a globally prevalent lifestyle factor with complex and sometimes paradoxical effects on cardiovascular health, particularly regarding acute coronary syndrome (ACS). Earlier epidemiological studies described a J-shaped relationship between alcohol consumption and ACS risk; however, emerging evidence has increasingly challenged the validity of this concept. Mendelian randomization studies, genetic data, and recent pooled analyses suggest that the apparent cardioprotective effects of light-to-moderate drinking are largely attributable to residual confounding, including abstainer bias and socioeconomic factors, rather than true causal mechanisms. In contrast, excessive alcohol intake is linked to increased oxidative stress, inflammation, hypertension, and prothrombotic states, all of which contribute to plaque instability and the precipitation of ACS. Additionally, acute heavy drinking episodes may induce coronary vasospasm and arrhythmias, further elevating ACS risk. Genetic factors, drinking patterns, and beverage types may also modulate the relationship between alcohol and ACS, indicating the need for personalized risk assessment. Understanding these complex interactions is essential for clinicians when counseling patients on alcohol consumption within the context of cardiovascular prevention. This review aims to delve into current evidence on the epidemiology and pathophysiology linking alcohol consumption with ACS, providing a nuanced perspective that balances potential protective effects with the significant risks associated with excessive alcohol use, as well as summarizing all medical societies’ recommendations regarding alcohol consumption and cardiovascular health. Full article

Background/Objectives: The growing prevalence of mental health problems among medical students is a global concern, with dietary patterns emerging as potential modifiable factors. This study aimed to explore and evaluate whether higher consumption of ultra-processed foods may be associated with greater symptoms of anxiety and depression. Methods: This was an exploratory cross-sectional study integrated into a previous cohort of medical students, conducted based on the guidelines for Strengthening the Reporting of Observational Studies in Epidemiology. Sixty-seven medical students completed a Food Frequency Questionnaire-based index. Dietary patterns and the associations between these patterns and symptoms of anxiety and/or depression were assessed statistically. Results: There were differences in the consumption of unprocessed or minimally processed foods, including fruits, vegetables, legumes and unsweetened juices between groups with/without anxiety or depression (p < 0.05). A higher intake of ultra-processed foods such as pizza, hot dogs, cereals high in fat and sugar, processed beverages and sweets was linked to greater symptoms (p < 0.05; Cohen’s d = 0.3–0.7). Three to four dietary patterns were identified, explaining between 60% and 86% of the variance. High consumption of cereals with added fat and sugars increased the risk by 7.4 times (OR = 7.4, 95% CI 1.2–12.2, p < 0.05). Conclusions: Dietary intake was associated, but not causally linked, to emotional symptoms among medical students. Lower consumption of unprocessed foods and higher intake of ultra-processed foods formed consistent behavioral profiles associated with anxiety and depression. Consuming more than three daily servings of cereals with added fat and sugar increased the risk of severe depressive symptoms by more than sevenfold, highlighting a strong dietary determinant. Future research should assess nutritional interventions aimed to improve mental health and academic performance in medical students. Full article

The consumption of water with very low mineral content (W-VLMC; water with total dissolved solids below 50 mg/L), despite limited and inconsistent evidence and the resulting knowledge gaps, has not been associated with health risks for the general population. However, certain population subgroups (those eating very unbalanced diets or avoiding certain foods, engaged in prolonged periods of fasting, and/or doing prolonged or strenuous exercise as well as pregnant or breastfeeding women) should be mindful of maintaining sufficient intake of all essential minerals through their food if regularly using this type of water as their main beverage. The rapid expansion of water filtration systems—often producing W-VLMC—creates a timely and valuable opportunity to advance research on the health implications of W-VLMC intake. As these systems become increasingly common in educational settings and homes, children represent a subgroup experiencing rising exposure to W-VLMC. Additional studies are needed to assess the health effects of such exposure from early childhood. A complementary yet contrasting perspective is that the use of water intended for human consumption—with stringent quality control standards—and natural mineral waters—inherently pure, thus eliminating the need for filtration—with higher mineralization in both types of water, may provide an additional dietary source of essential minerals, especially for all the population subgroups mentioned above. Full article

Background/Objectives: Within public health and preventive nutrition, food labeling plays a critical role in supporting healthier dietary behaviors. This study aimed to evaluate the behaviors, perceptions, and nutritional literacy of young adults from Iași, Romania, regarding simple carbohydrates (SCHO) consumption and food label-reading habits. Materials and Methods: A cross-sectional survey was conducted between May–June 2023 using 20-item Likert-scale questionnaire completed by 150 participants aged 18–30 years. Statistical analysis included descriptive metrics, Chi-square tests, and Pearson’s correlation, with significance set at p ≤ 0.05. Results: The cohort consisted of 72% females (N = 108) and 28% males (N = 42), with 42.7% (N = 64) holding university degrees. Although 22% (N = 33) considered SCHO consumption highly important, only 13.3% (N = 20) frequently read nutrition labels (p ≤ 0.05). Dietary patterns showed that 27.3% primarily consumed sweets, while others combined sweets with carbonated beverages, dairy products, or whole grains; overall, 44% (N = 66) reported frequent sweet consumption. Label reading was highest for sweets (40.7%), lower for dairy products (19.3%) and soft drinks (9.3%). Additionally, 30.7% (N = 46) checked only expiration dates, whereas just 11.3% (N = 17) reviewed nutritional content. Trust in label accuracy was low: 48% (N = 72) expressed neutrality and 14% (N = 21) disagreed. Although 77.3% (N = 116) recognized the link between sugar intake and dental caries, only 23.3% (N = 35) felt well informed about oral health risks. Taste dominated food selection (68.7%), while nutritional value was cited by 16.7% (N = 25). Conclusions: Young adults from Iași demonstrated notable gaps in nutritional literacy and suboptimal dietary behaviors, emphasizing the need for structured educational strategies to improve preventive practices relevant to systemic and oral health. Full article

Minthostachys verticillata (Griseb.) Epling, commonly known as peperina, is an aromatic species endemic to Argentina and traditionally used for gastrointestinal ailments. Despite its extensive folkloric use and inclusion in the Argentine Pharmacopoeia, its aqueous extract (the most commonly consumed preparation) has been described in terms of major phytochemical groups, and, currently, no studies have investigated its effects on key intestinal epithelial mechanisms. This plant is also employed in the production of beverages and herbal blends, and its massive consumption highlights the importance of its scientific study. Here, the aqueous extract of M. verticillata was characterized by liquid chromatography–tandem mass spectrometry, leading to the identification of fourteen polyphenolic compounds. In intestinal cell models, the extract displayed high IC₅₀ values, supporting its safety, and exhibited concentration-dependent bioactivity. In HT-29 cells, it modulated NF-κB activation induced by TNF-α and reduced LPS-stimulated IL-8 production. Pretreatment of Caco-2 monolayers prevented the decrease in transepithelial electrical resistance, increased FITC–dextran permeability, and nitric oxide production triggered by an inflammatory cocktail. Additionally, the extract inhibited HT-29 cell migration. These results demonstrate that M. verticillata aqueous extract exerts anti-inflammatory, barrier-protective, and anti-migratory effects in vitro, providing novel insights into how its polyphenolic composition may underlie these biological activities, supporting its traditional use and potential applications in intestinal health. Full article

Background/Objectives: Mini-tablets have gained popularity as a pediatric dosage form owing to their high acceptability. Since 2022, the Showa University Hospital has prescribed acetylsalicylic acid (ASA) mini-tablets to pediatric patients with Kawasaki disease (KD). In this study, we investigated the real-world, at-home administration status of ASA mini-tablets in pediatric patients with KD. Methods: This retrospective study included 14 pediatric patients with KD on ASA mini-tablet therapy between November 2022 and October 2024. Medication administration completeness, mood changes during administration, administration patterns, beverages consumed, and swallowing-related events were analyzed. Associations between changes in the administration pattern or beverage consumption and swallowing events or mood changes were evaluated. Serious adverse events and coronary artery aneurysms were assessed using medical records. Results: Patients were prescribed ASA mini-tablets for a mean duration of 60.9 days. No serious adverse events or coronary aneurysms were observed. Among the 679 medication records, 5 swallowing-related events were identified. No mood changes following administration were observed in >90% of cases. The mood worsened to “Bad” once, with no further deterioration. The “All at once” administration pattern occurred in 64% of occasions across 12 patients (age: 9–79 months). Patients aged <3 years used medication-assisted jelly, whereas older patients mostly used water. Conclusions: ASA mini-tablets can be safely administered at home with minimal swallowing problems. Patients completed full doses irrespective of tablet number, age, administration pattern, or beverage, supporting ASA mini-tablets as an acceptable dosage form option for ASA in KD. Full article

Background: Smartphones and social media (SPSM) use has become an integral part of life around the globe, including the United Arab Emirates (UAE). This study investigated the association and strength of association between SPSM screen time and dietary and physical activity behaviours among adults in the UAE. Methods: A cross-sectional household-based study was conducted in the Emirate of Abu Dhabi, UAE, between June 2024 and March 2025. A total of 5152 adults aged 18 years and above were selected through a multistage stratified random sampling method. Data were obtained from structured interviews that collected information about demographics, SPSM use time, dietary habits and physical activity levels. The statistical analyses conducted using SPSS software. Results: The mean SPSM usage time was 277.6 ± 165.6 and 234.6 ± 170.8 min per day for smartphone and social media, respectively. Social networking was the main purpose for smartphone (71.7%) and social media (74.8%) usage. Higher SPSM use was significantly associated with more frequent consumption of unhealthy foods, including sugar-sweetened beverages, fast food, and energy drinks (p < 0.001). The associations between SPSM and dietary behaviour and physical activity were generally weak. Only social media usage time was significantly associated with physical activity (p = 0.012). Conclusion: SPSM use time is associated with dietary patterns and physical activity among adults in the UAE. Higher smartphone and social media screen time was associated with increased consumption of unhealthy foods and lower physical activity; however, the relationships were weak to moderate. Full article