- Article
Solubility Improvement of Benexate through Salt Formation Using Artificial Sweetener
- Okky Dwichandra Putra,
- Daiki Umeda,
- Eriko Fujita,
- Tamami Haraguchi,
- Takahiro Uchida,
- Etsuo Yonemochi and
- Hidehiro Uekusa
Benexate, a drug used clinically as a defensive type anti-ulcer agent, has poor solubility and a bitter taste. To improve its solubility, a crystal engineering approach was proposed with the formation of novel salts using an artificial sweetener as a...