Search Results (1,406)

Optical sensor technologies are reshaping obesity detection by enabling non-invasive, dynamic analysis of biomechanical and morphological biomarkers. This review synthesizes recent advances in three key areas: optical gait analysis, vision-based pose estimation, and depth-sensing voxel modeling. Gait analysis leverages optical sensor arrays and video systems to identify obesity-specific deviations, such as reduced stride length and asymmetric movement patterns. Pose estimation algorithms—including markerless frameworks like OpenPose and MediaPipe—track kinematic patterns indicative of postural imbalance and altered locomotor control. Human voxel modeling reconstructs 3D body composition metrics, such as waist–hip ratio, through infrared-depth sensing, offering precise, contactless anthropometry. Despite their potential, challenges persist in sensor robustness under uncontrolled environments, algorithmic biases in diverse populations, and scalability for widespread deployment in existing health workflows. Emerging solutions such as federated learning and edge computing aim to address these limitations by enabling multimodal data harmonization and portable, real-time analytics. Future priorities involve standardizing validation protocols to ensure reproducibility, optimizing cost-efficacy for scalable deployment, and integrating optical systems with wearable technologies for holistic health monitoring. By shifting obesity diagnostics from static metrics to dynamic, multidimensional profiling, optical sensing paves the way for scalable public health interventions and personalized care strategies. Full article

Background: Hypometabolism of the thalamus has been reported in epilepsy patients. This study aimed to investigate the prognostic value of thalamic metabolic activity in children with epilepsy. Methods: A total of 200 children with epilepsy and 237 children without epilepsy (sex- and age-matched control group) underwent 18F-FDG PET/CT in this study. Localization of the interictal hypometabolic epileptic focus was performed visually. Bilateral thalamic metabolic activity was evaluated qualitatively (thalamic FDG uptake in relation to the cerebral cortex) and semi-quantitatively (SUV max, normalized SUV (ratio to ipsilateral cerebellum), and absolute asymmetric index (AAI). Results: A total of 133 patients (66.5%) with epilepsy showed cerebral cortical hypometabolism in the interictal 18F-FDG PET study; there were 76 patients on the right side, 55 patients on the left side, and two patients on both sides. Of these 133 patients, 45 also had visually observed asymmetric hypometabolism in the thalamus. Semi-quantitatively, asymmetry was more prominent in epileptic patients. AAI was a more sensitive variable than other variables. Average AAIs were 3.89% and 7.36% in the control and epilepsy patients, respectively. Metabolic activity in the thalami was significantly reduced in epileptic patients compared to the control group. Associated hypometabolism of the ipsilateral thalamus was observed in 66.5% of epileptic patients with a focal cortical defect semi-quantitatively. Overall, 61 out of 200 patients showed thalamus hypometabolism. Some 51 out of 61 patients (83.6%) with thalamus hypometabolism showed refractory disease; however, the refractory disease was noted in 90 out of 139 (64.7%) patients without thalamus hypometabolism. Brain surgery was performed in 86 epileptic patients (43%). Some 35 out of 86 patients had thalamus hypometabolism. Recurrence of epilepsy was observed more in patients with thalamus hypometabolism (48% vs. 25%), with p ≤ 0.01. Conclusion: This study suggests that patients with thalamus metabolic abnormalities may be more medically resistant to therapy and less responsive to surgical treatments. Therefore, the thalamus metabolic abnormality could be used as a prognostic sign in pediatric epilepsy. Recent studies have also suggested that incorporating thalamic metabolic data into clinical workflows may improve the stratification of treatment-resistant epilepsy in children. Full article

Autism spectrum disorder (ASD) is increasingly associated with microbial and metabolic disturbances, including the altered production of gut-derived uremic toxins. We investigated urinary concentrations of five representative uremic toxins—indoxyl sulfate (IS), p-cresyl sulfate (PCS), trimethylamine N-oxide (TMAO), asymmetric dimethylarginine (ADMA), and symmetric dimethylarginine (SDMA)—in 161 children with ASD and 71 healthy controls. Toxins were measured using LC-MS/MS and were normalized to creatinine. Subgroup analyses were performed by sex, age group (2–5.9 vs. 6–17 years), and autism severity based on the Childhood Autism Rating Scale (CARS). In addition to individual concentrations, we calculated the total toxin burden, proportional contributions, and functional ratios (IS/PCS, PCS/TMAO, and IS/ADMA). While individual toxin levels did not differ significantly between groups, stratified analyses revealed that PCS was higher in girls and in severe cases of ASD, whereas IS and TMAO were reduced in younger and more severely affected children. The functional ratios shifted consistently with severity—IS/PCS declined from 1.69 in controls to 0.99 in severe cases of ASD, while PCS/TMAO increased from 12.2 to 20.5. These patterns suggest a phenolic-dominant microbial signature and an altered host–microbial metabolic balance in ASD. Functional toxin profiling may offer a more sensitive approach to characterizing metabolic disturbances in ASD than concentration analysis alone. Full article

This article concerns a Cournot duopoly game with homogeneous expectations. The cost functions of the two players are assumed to be asymmetric to capture possible asymmetries in firms’ technologies or firms’ input costs. Large values of the speed of adjustment of the players destabilize the Nash Equilibrium (N.E.) and cause the appearance of a chaotic trajectory in the Discrete Dynamical System (D.D.S.). The scope of this article is to control the chaotic dynamics that appear outside the stability field, assuming asymmetric cost functions of the two players. Specifically, one player uses linear costs, while the other uses nonlinear costs (quadratic or cubic). The cubic cost functions are widely used in the Economic Dispatch Problem. The delayed feedback control method is applied by introducing a new control parameter at the D.D.S. It is shown that larger values of the control parameter keep the N.E. locally asymptotically stable even for higher values of the speed of adjustment. Full article

At present, the redundant structures are one of the most effective methods for solving magnetic levitation bearing coil failure. Coil failure causes residual effective magnetic poles to form different support structures and even asymmetrical structures. For the magnetic bearing with redundant structures, how to construct the electromagnetic force (EMF) that occurs under different support structures to achieve support reconstruction is the key to realizing fault tolerance control. To reveal the support reconstruction mechanism of magnetic bearing with a redundant structure, firstly, this paper takes a single-degree-of-freedom magnetic suspension body as an example to conduct a linearization theory analysis of the offset current, clarifying the concept of the current distribution matrix (CDM) and its function; then, the nonlinear EMF mode of magnetic bearing with an eight-pole is constructed, and it is linearized by using the theory of bias current linearization. Furthermore, the conditions of no coils fail, the 8th coil fails, and the 6–8th coils fail are considered, and, with the maximum principle function of EMF, the corresponding current matrices are obtained. Meanwhile, based on the CDM, the corresponding magnetic flux densities were calculated, proving that EMF reconstruction can be achieved under the three support structures. Finally, with the CDM and position control law, a fault-tolerant control system was constructed, and the simulation of the magnetic bearing with a redundant structure was carried out. The simulation results reveal the mechanism of support reconstruction with three aspects of rotor displacement, the value and direction of currents that occur in each coil. The simulation results show that, in the 8-pole magnetic bearing, this study can achieve support reconstruction in the case of faults in up to two coils. Under the three working conditions of wireless no coil failure, the 8th coil fails and the 6–8th coils fail, the current distribution strategy was adjusted through the CDM. The instantaneous displacement disturbance during the support reconstruction process was less than 0.28 μm, and the EMF after reconstruction was basically consistent with the expected value. Full article

Enhancing the resilience of renewable energy systems in ultra-weak grids is crucial for promoting sustainable energy adoption and ensuring a reliable power supply during disturbances. Ultra-weak grids characterized by a very low Short-Circuit Ratio, less than 2, and high grid impedance significantly impair voltage and frequency stability, imposing challenging conditions for Inverter-Based Resources. To address these challenges, this paper considers a 110 KVA, three-phase, two-level Voltage Source Converter, interfacing a 700 V DC link to a 415 V AC ultra-weak grid. X/R = 1 is controlled using Sinusoidal Pulse Width Modulation, where the Grid-Connected Converter operates in Grid-Forming Mode to maintain voltage and frequency stability under a steady state. During symmetrical and asymmetrical faults, the converter transitions to Grid-Following mode with current control to safely limit fault currents and protect the system integrity. After fault clearance, the system seamlessly reverts to Grid-Forming Mode to resume voltage regulation. This paper proposes an improved control strategy that integrates voltage feedforward reactive power support and virtual capacitor-based virtual inertia using Active Disturbance Rejection Control, a robust, model-independent controller, which rapidly rejects disturbances by regulating d and q-axes currents. To test the practicality of the proposed system, real-time implementation is carried out using the OPAL-RT OP4610 platform, and the results are experimentally validated. The results demonstrate improved fault current limitation and enhanced DC link voltage stability compared to a conventional PI controller, validating the system’s robust Fault Ride-Through performance under ultra-weak grid conditions. Full article

Considering the lightweight requirement of modular multilevel converter (MMC), the implementation of arm multiplexing significantly improves submodule utilization and achieves remarkable lightweight performance. However, the challenges of overvoltage and energy imbalance during pole-to-ground fault still exist. To address these issues, this paper proposes a hybrid half-wave alternating MMC (HHA-MMC) and presents its fault ride-through strategy. First, a transient equivalent model based on topology and operation principles is established to analyze fault characteristics. Depending on the arm’s alternative multiplexing feature, the half-wave shift non-blocking fault ride-through strategy is proposed to eliminate system overvoltage and fault current. Furthermore, to eliminate energy imbalance caused by asymmetric operation during non-blocking transients, dual-modulation energy balancing control based on the third-harmonic current and the phase-shifted angle is introduced. This strategy ensures capacitor voltage balance while maintaining 50% rated power transmission during the fault period. Finally, simulations and experiments demonstrate that the lightweight HHA-MMC successfully accomplishes non-blocking pole-to-ground fault ride-through with balanced arm energy distribution, effectively enhancing power supply reliability. Full article

Housing prices have recently risen sharply in many countries, primarily linked to the global credit cycle. Although various factors play a role, the ability of developing countries to navigate this cycle and maintain autonomous monetary policies is crucial. This paper introduces a dynamic macroeconomic model featuring a housing production sector within an imperfect banking framework. It captures key housing and economic dynamics in advanced and emerging economies. The analysis shows domestic liquidity policies, such as bank capital requirements, reserve ratios, and currency devaluation, can stabilize investment and production. However, their effectiveness depends on foreign interest rates and liquidity. Stabilizing housing prices and risk-free bonds is more effective in high-interest environments, while foreign liquidity shocks have asymmetric impacts. They can boost or lower the effectiveness of domestic policy, depending on the country’s level of financial development. These findings have several policy implications. For example, foreign capital controls would be adequate in the short term but not in the long term. Instead, governments would try to promote the development of local financial markets. Controlling debt should be a target for macroprudential policy as well as promoting saving instruments other than real estate, especially during low interest rates. Full article

With the accelerated development of urban underground spaces, prefabricated tunnel linings have become a research focus due to their advantages in construction efficiency and cost effectiveness. However, issues such as stress concentration at joints and insufficient overall stability hinder their broader application. This study investigates a cut-and-cover prefabricated tunnel project in the Chongqing High-Tech Zone through scale model tests and numerical simulations to systematically compare the mechanical behaviors of cast-in situ linings and three-segment prefabricated linings under surrounding rock loads. The experimental results show that the ultimate bearing capacity of the prefabricated lining is 15.3% lower than that of the cast-in situ lining, with asymmetric failure modes and cracks concentrated near joint regions. Numerical simulations further reveal the influence of joint stiffness on structural performance: when the joint stiffness is 30 MN·m/rad, the bending moment of the segmented lining decreases by 37.7% compared to the cast-in situ lining, while displacement increments remain controllable. By optimising joint pre-tightening forces and stiffness parameters, prefabricated linings can achieve stability comparable to cast-in situ structures while retaining construction efficiency. This research provides theoretical and technical references for the design and construction of open-cut prefabricated tunnel linings. Full article

In this paper, we provide a novel extended mixed differential model that is appealing to users because of its numerous free parameters. The motivation of this research arises from the opportunity for a general investigation of some outstanding classical and novel dynamical models. The higher energy levels known in the literature can be governed by appropriately added correction factors. Furthermore, the different applications of the considered model can be achieved only after a proper parameter calibration. All these necessitate the use of diverse optimization and approximation techniques. The proposed extended model is especially useful in the important field of decision making, namely the antenna array theory. This is due to the possibility of generating high-order Melnikov polynomials. The work is a natural continuation of the authors’ previous research on the topic of chaos generation via the term ${x\left|x\right|}^{a-1}$. Some specialized modules for investigating the dynamics of the proposed oscillators are provided. Last but not least, the so-defined dynamical model can be of interest for scientists and practitioners in the area of antenna array theory, which is an important part of the decision-making field. The stochastic control of oscillations is also the subject of our consideration. The underlying distributions we use may be symmetric, asymmetric or strongly asymmetric. The same is true for the mass in the tails, too. As a result, the stochastic control of the oscillations we purpose may exhibit a variety of possible behaviors. In the final section, we raise some important issues related to the methodology of teaching Master’s and PhD students. Full article

Purpose: This pilot study aimed to evaluate how deviations in X-ray tube head angulation and digital sensor alignment affect the radiographic measurement of the profile angle in CAD-CAM abutments. Materials and Methods: A mandibular model was used with five implant positions (central, buccal, and lingual offsets). Custom CAD-CAM abutments were designed with identical bucco-lingual direction contours and varying mesio-distal asymmetry for the corresponding implant positions. Periapical radiographs were acquired under controlled conditions by systematically varying vertical tube angulation, horizontal tube angulation, and horizontal sensor rotation from 0° to 20° in 5° increments for each parameter. Profile angles, interthread distances, and proximal overlaps were measured and compared with baseline STL data. Results: Profile angle measurements were significantly affected by both X-ray tube and sensor deviations. Horizontal tube angulation produced the greatest profile angle distortion, particularly in buccally positioned implants. Vertical x-ray tube angulations beyond 15° led to progressive underestimation of profile angles, while horizontal tube head rotation introduced asymmetric mesial–distal variation. Sensor rotation also caused marked interthread elongation, in some cases exceeding 100%, despite vertical projection being maintained. Profile angle deviations greater than 5° occurred in multiple conditions. Conclusions: X-ray tube angulation and sensor alignment influence the reliability of profile angle measurements. Radiographs with > 10% interthread elongation or crown overlap may be inaccurate and warrant re-acquisition. Special attention is needed when imaging buccally positioned implants. Full article

The design of nanoscale electronic components remains a major challenge because we have limited control over the chemical and physical properties of their molecular constituents. Even subtle structural or compositional modifications can significantly alter their electronic behavior. Consequently, updating a molecular component often necessitates developing a new model from scratch. In this study, we present a comprehensive analysis of the rectification properties of a promising molecular diode initially proposed by Aviram and Van Dyck. The model has been systematically decomposed into fundamental building blocks, enabling the electron transport process to be examined both as an integrated event and as a sum of cooperative interactions. Our findings reveal that certain motifs—such as the D-σ-A architecture—play a significant role in rectification. However, achieving high-performance molecular rectifiers also requires cooperative interplay with other structural elements that contribute to rectification, such as asymmetric molecule–metal contacts. In this study, we conduct a detailed investigation of the roles these elements play in shaping the rectifying characteristics, and we further interpret their effects by analyzing the dominant transport channels under forward and backward bias conditions. This deeper understanding of the transport mechanism offers greater control over the system and opens the door for rational design strategies for improving rectification efficiency in future molecular devices. Full article

Purpose: The aim of this study was to compare the one-year efficacy of three spectacle lens designs, highly aspherical lenslets (HALs), horizontally asymmetric peripheral defocus (HAPD) lenses, and standard single vision lenses (SVLs) in slowing myopia progression in school-aged children. Methods: In this prospective, non-randomized study, 57 children, aged 8–17 years, were grouped based on the type of lenses worn: HAL (n = 16), HAPD (n = 21), or SVL (n = 20). Comprehensive ophthalmologic examinations were performed at baseline, 6 months, and 12 months. Outcome measures included spherical equivalent refraction (SER), spherical refraction (SR), cylindrical refraction (CR), and axial length (AL). Data were analyzed using non-parametric tests with significance set at p < 0.05. Results: All groups showed some progression in SER and AL over 12 months. The HAL group demonstrated the smallest median SER change (−0.3 D), compared to HAPD (−0.5 D) and SVL (−0.4 D), though group differences were not statistically significant (p = 0.111). Axial elongation was significantly lower in the HAL group (0.1 mm, IQR: 0.0–0.2 mm) compared to HAPD and SVL (both 0.2 mm, p < 0.0001). CR remained stable in all groups, with no clinically meaningful changes. The HAPD groups showed no advantages over SVL in any parameter. Conclusions: Among the three lens types studied, HAL lenses were the most effective in reducing both refractive and axial myopia progression over 12 months. These findings support their use as a reliable intervention in pediatric myopia control. Full article

The present study intends to assess the ratcheting response of SA508 and SA333 steel alloys subjected to asymmetric loading cycles at various operating temperatures of 298, 573, and 623K through a hardening framework developed by Ahmadzadeh–Varvani (A-V) and the finite element analysis structured by the Chaboche hardening model (CH) in the ANSYS software program. The dynamic recovery terms in the A-V and CH hardening framework consisted of temperature-dependent parameters and functions to address the dynamic strain aging (DSA) phenomenon at high temperatures of 573 and 623 K. The DSA phenomenon reported at elevated temperatures was attributed to the interactions of solute atoms and dislocations with a certain temperature, resulting in higher material strength and lower ratcheting deformation. The coefficients of these frameworks were analytically determined through stress–strain hysteresis loops obtained from the strain-controlled cyclic tests. The FE analysis was applied to numerically evaluate backstress evolution through use of the CH model. Two popular nonlinear brick and tetrahedron element types were examined to study the convergence of the elemental system with various numbers of elements. This ensured the independence of the simulated results from the number of elements and their convergence. The simulated ratcheting responses for brick and tetrahedron solid elements were compared to those predicted analytically by the A-V hardening rule and experimentally measured values. The predicted and simulated ratcheting data were found to be in good agreement with the measured data. The predicted and simulated ratcheting results generated using the A-V and FEA approaches showed $R^2$ values of 0.96 and 0.85, respectively, when compared with the experimental data. Full article

We explore chaos, local dynamics, codimension-one, and codimension-two bifurcations of an asymmetric discrete predator–prey model. More precisely, for all the model’s parameters, it is proved that the model has two boundary fixed points and a trivial fixed point, and also under parametric conditions, it has an interior fixed point. We then constructed the linearized system at these fixed points. We explored the local behavior at equilibria by the linear stability theory. By the series of affine transformations, the center manifold theorem, and bifurcation theory, we investigated the detailed codimensions-one and two bifurcations at equilibria and examined that at boundary fixed points, no flip bifurcation exists. Furthermore, at the interior fixed point, it is proved that the discrete model exhibits codimension-one bifurcations like Neimark–Sacker and flip bifurcations, but fold bifurcation does not exist at this point. Next, for deeper understanding of the complex dynamics of the model, we also studied the codimension-two bifurcation at an interior fixed point and proved that the model exhibits the codimension-two 1:2, 1:3, and 1:4 strong resonances bifurcations. We then investigated the existence of chaos due to the appearance of codimension-one bifurcations like Neimark–Sacker and flip bifurcations by OGY and hybrid control strategies, respectively. The theoretical results are also interpreted biologically. Finally, theoretical findings are confirmed numerically. Full article