Search Results (294)

In the present paper, we studied the interaction of microwave radiation with conductive indium tin oxide (ITO) coatings deposited on a borosilicate glass. The experiments were carried out with the ITO films, the thickness of which varied in the range from 85 to 607 nm. The transmittance and reflectivity of the ITO film/K108 glass structures were measured in the frequency region from 3 to 23 GHz. Theoretical modeling of the spectra was performed by means of the transfer matrix method. It was shown that for a given thickness of the glass substrate, the transmission and reflection spectra of the ITO film/K108 glass structures were fully determined by only one parameter of the ITO film, namely, its DC sheet resistivity. The considered model predicts an increase in maximum microwave shielding effectiveness up to 45.6 dB with a decrease in DC sheet resistivity to 1 Ohm/sq. ITO coatings with DC sheet resistivities down to 2.3 Ohm/sq have been experimentally investigated. The model microwave transmittance and reflectivity spectra were in good agreement with the experimental ones. In particular, the coefficient of determination for the transmittance spectra was rather high: R² > 0.93. It was experimentally demonstrated that applying antireflective coatings on both sides of the ITO film/K108 glass microwave shielding filter significantly improved its transparency in the operating optical range. A filter has been created that provides microwave shielding effectiveness of 38.7 dB with an average transmission coefficient of 0.81 in the visible range. Full article

Background/Objectives: Vesicular Stomatitis Virus (VSV)-vectored vaccines represent a versatile platform for the development of vaccines against infectious diseases. Replication-competent recombinant VSV vectors in which the native glycoprotein (G) is replaced with a heterologous antigen (rVSVΔG) are widely used and have demonstrated clinical success. In addition to antigen-specific responses, these vaccines induce humoral immunity directed against vector components, which primarily reflects vector exposure and contributes to the overall characterization of vaccine-induced immunity. Standardized assays for quantifying such vector-directed responses are therefore of increasing importance. Methods: We developed and qualified a quantitative enzyme-linked immunosorbent assay (ELISA) for the detection of human IgG antibodies against VSV-Nucleoprotein (N). Assay development included optimization of antigen coating, blocking conditions, and detection reagents. A 10-point standard curve was established using pooled human serum, and assay performance was evaluated by assessing dynamic range, sensitivity, cut point, dilutional linearity, precision, robustness, and sample stability. Results: The optimized assay utilized a coating concentration of 2 μg/mL VSV-N antigen (100 ng/well) and 1% casein as the blocking buffer. The assay demonstrated a dynamic range of 0.33–41.66 arbitrary units per milliliter (AU/mL) with excellent curve fit (R² > 0.996). The cut point was established at an OD₄₅₀ of 0.286. Precision across intra-assay, inter-assay, and inter-operator evaluations met predefined acceptance criteria (≤25% CV). The assay was robust across different plate washers and readers and maintained performance following up to three freeze–thaw cycles. Conclusions: This study describes a robust and reproducible ELISA for quantifying anti-VSV-N IgG responses. The assay provides a fit-for-purpose tool for assessing vector-directed humoral immunity and supports standardized immunogenicity evaluations across VSV-vectored vaccine studies. Full article

The amniotic membrane is widely recognized in regenerative medicine due to its rich content of extracellular matrix proteins and growth factors that confer anti-inflammatory and pro-regenerative properties. However, its rapid degradation restricts its standalone clinical use. To overcome these limitations, we developed biofilms by incorporating decellularized human amniotic membrane matrix (dHAM) into polycaprolactone (PCL) and polyvinylpyrrolidone (PVP) matrices using spin-coating. Bone marrow-derived mesenchymal stem cells (BM-MSCs) were used to evaluate film biocompatibility through cell viability, proliferation, and wound healing migration assays. Surface characterization was performed using contact angle measurements, Attenuated Total Reflectance-Fourier Transform Infrared (ATR-FTIR) spectroscopy, and scanning electron microscopy. Soluble dHAM extracts (4–6 mg/mL) significantly enhanced BM-MSC proliferation at 48 h compared to controls (p ≤ 0.01 and p ≤ 0.0001). Both PCL-dHAM and PVP-dHAM biofilms exhibited high cell viability (>90%) and improved initial adhesion. Notably, dHAM incorporation significantly increased wound closure rates at 24 h, reaching 98.47% for PCL-dHAM and 93.13% for PVP-dHAM, compared to 76.56% and 64.20% for pure polymers (p = 0.0001). All scaffolds maintained hydrophilic surfaces (<90°), favorable for cell interaction. The integration of dHAM into PCL and PVP by spin-coating produces biofilms biocompatible with enhanced regenerative potential, representing promising candidates for wound healing applications. In conclusion, these coatings support BM-MSC adhesion, proliferation, and migration, while significantly accelerating wound closure, underscoring their value as advanced bioactive coatings for regenerative medicine. Full article

The evolution of 193 nm deep-ultraviolet (DUV) lithography toward high numerical aperture (NA > 1.35) presents challenges approaching physical limits for antireflective (AR) coatings on strongly curved lens elements. In this study, a full-stack multi-objective optimization framework is developed by coupling the Non-dominated Sorting Genetic Algorithm II (NSGA-II) with the Transfer Matrix Method (TMM) to optimize a 7-layer LaF₃/MgF₂ system on strongly curved substrates ($R=150$ mm). The model integrates material dispersion, thermo-optic effects, deposition flux deviations, and manufacturing thickness constraints. Following 1500 generations of optimization and TOPSIS-based decision-making, the selected Pareto optimal solution achieves a full-aperture average reflectance of 1.3633% and a radial uniformity of 9.5037%. The design further exhibits high environmental robustness with a thermal drift of 0.0019% and a residual stress of 39.23 MPa. These results demonstrate that the proposed method overcomes the critical process bottleneck of achieving full-aperture uniformity below 10% on strongly curved optics. This framework provides a general paradigm for the robust design of next-generation ultra-precision DUV optical systems, effectively balancing theoretical depth with engineering feasibility. Full article

Photovoltaic modules require efficient sunlight modulation, including enhanced visible transmittance and conversion of unused ultraviolet light. This study develops a synthetic optical coating that achieves both functions by integrating down-conversion BAM (BaMgAl₁₀O₁₇:Eu²⁺, Mn²⁺) nanophosphors into a silica anti-reflection sol. The key novelty lies in a synergistic surface engineering strategy that decouples dispersion stabilization from luminescence protection. Five dispersants are systematically compared under combined ball and sand milling. The polyester-modified acrylic long-chain dispersant (DK062) yields a stable nanodispersion with an average particle size of 228 nm and a Zeta potential of −7.61 mV, effectively suppressing re-agglomeration while retaining high photoluminescence. Subsequent surface modification with KH570 grafts a dense silane passivation layer via Si–O–M covalent bonds, further increasing the photoluminescence intensity by 1.39-fold. The optimized nanophosphors are incorporated into a commercial anti-reflection sol and dip-coated onto photovoltaic glass. At a doping concentration of 2‰ and a withdrawal speed of 8 mm/s, the resulting DCSAR coating exhibits an average transmittance of 91.16%—slightly higher than that of the pure anti-reflection coating (90.96%)—while showing strong green emission at 515 nm. Industrial on-site testing further demonstrates an average transmittance of 94.20%–94.31% with uniform green emission. This work provides a scalable route to fabricate highly transparent, light-converting anti-reflection coatings by combining dispersant-assisted milling and silane passivation. Full article

Laser-induced damage of sol–gel SiO₂ antireflection coatings remains a key reliability issue in high-power laser systems because porous networks, residual hydroxyl groups, and defect-related absorption centers can trigger localized heating and stress concentration under nanosecond irradiation. In this work, continuous-wave CO₂ laser conditioning was used as a localized post-treatment method to regulate the microstructure of sol–gel SiO₂ coatings on fused silica substrates. The revised manuscript clarifies the processing window, scanning parameters, laser damage testing protocol, and the sample-specific nature of the reported LIDT values. Laser conditioning induces partial densification of the porous coating, dehydration of Si-OH groups, relaxation of the Si-O-Si network, and enhancement of mechanical properties. Under the optimized conditioning condition, the surface roughness decreases from 14.08 nm to 9.76 nm, and the LIDT at 1064 nm increases from 4.8 J/cm² to 7.0 J/cm². The LIDT values are discussed as a relative microstructure–property comparison for the present coating system rather than as the upper technological limit of sol–gel silica coatings. Combined FTIR analysis, thermal simulation, morphology observation, and damage probability analysis indicate that the improvement originates from the combined effects of reduced defect absorption, moderated porosity, improved heat dissipation, and enhanced resistance to thermally induced cracking. The results provide a mechanism-guided strategy for using CO₂ laser conditioning to tune sol–gel silica coatings while also identifying the need for further validation on higher-LIDT coatings and at application-relevant wavelengths. Full article

Cyclophosphamide (CTX)-induced premature ovarian failure (POF) is characterized by disruption of the follicular microenvironment, granulosa-cell loss, endocrine imbalance, and oxidative-inflammatory injury. Here, we evaluated two multi-bioactive formulations developed to enhance ovarian stress resilience: a base formulation containing coenzyme Q10, calcium L-5-methyltetrahydrofolate, and Vitex agnus-castus extract (Base), and a urolithin A-enriched formulation (Base + U). Using a CTX-induced female C57BL/6 mouse model, we integrated phenotypic, histological, endocrine, oxidative-inflammatory, and transcriptional readouts to assess efficacy and mechanistic consistency. CTX markedly reduced ovarian index, disrupted estrous cyclicity, shifted follicle development toward atresia, increased granulosa-cell apoptosis, and caused endocrine dysregulation, including decreased anti-Müllerian hormone and estradiol and increased GnRH, FSH, and LH. CoQ10, Base, and Base + U each partially alleviated these abnormalities, improving ovarian index and coat condition, showing a trend toward improved follicular distribution, and normalizing hormone profiles. CTX also induced an ovarian oxidative-inflammatory shift, as reflected by decreased GSH-Px, increased MDA, and elevated IL-1β, IL-6, and TNF-α, all of which were attenuated by the interventions. Notably, Base + U more effectively reduced lipid peroxidation and TNF-α than Base alone. Consistently, ovarian transcripts related to follicle responsiveness and steroid regulation, including Fshr, Esr1, and Hsd17b2, were restored, whereas hypothalamic qRT-PCR analysis did not reveal robust transcriptional alterations within the intervention window. These findings suggest that the urolithin A-enhanced formulation partially alleviates CTX-induced ovarian dysfunction by suppressing oxidative-inflammatory stress and preserving granulosa-cell and follicle fate. Full article

Chalcopyrite-based thin-film solar cells have great potential for various applications, such as top or bottom cells in tandem devices, in addition to their use as standard single-junction modules due to their tuneable bandgap energy. A bandgap energy E_g > 1.5 eV should be targeted to realize a wide-bandgap top cell, e.g., by increasing the [Ga]/([Ga] + [In]) (GGI) ratio in Cu(In,Ga)Se₂ (CIGS) cells to the range of 0.7–1. A second approach is targeting the second theoretical efficiency maximum at a little lower E_g = 1.34 eV with a GGI around 0.6 for high-efficiency single-junction applications with reduced electrical losses. An industry-relevant (Ag,Cu)(In,Ga)Se₂ (ACIGS) co-evaporation process for wide-bandgap cells fabricated with GGI ratios above 0.6, with moderate [Ag]/([Ag] + [Cu]) (AAC) ratios < 0.1 and in-line RbF-PDT, was established on molybdenum-coated soda-lime glass substrates. Both measures, Ag alloying and RbF-PDT, can increase power conversion efficiency (PCE) mainly due to improved open-circuit voltage (V_OC). In addition, Ag addition can increase fill factor (FF)_, leading to an increase in the PCE for cells with GGI > 0.6 compared to Ag-free reference cells. (Zn,Mg)O, either with a [Mg]/([Mg] + [Zn]) ratio of 0.15 or 0.25, is a good option as high-resistive layer replacing the commonly used i-ZnO in combination with a CdS buffer. Our best ACIGS wide-bandgap solar cells with RbF-PDT and Zn_0.85Mg_0.15O (without anti-reflective coating (ARC)) from various experimental campaigns show a PCE of 12.7% (E_g = 1.50 eV), and with a slightly reduced E_g of 1.45 eV a PCE of 15.5%, with V_OC of 933 mV (V_OC deficit of 517 mV), and a good FF of 73.2%. In the case when the bandgap is significantly lowered to 1.34 eV (GGI = 0.61), to the second theoretical efficiency maximum, we achieved a PCE of 18.2% with ARC for an Ag-free CIGS cell with RbF-PDT. For this cell with a CdS/i-ZnO buffer system the V_OC deficit is 480 mV, and the FF is 78.1%. Full article

Background and Objectives: Bladder neck stenosis (BNS) and vesicourethral anastomotic stenosis (VUAS) are challenging complications following prostate surgery and radiation therapy, with recurrence rates reaching 30–60% after conventional endoscopic management. The Optilume^® paclitaxel drug-coated balloon (DCB) has emerged as a novel minimally invasive treatment combining mechanical dilation with local anti-fibrotic drug delivery. This narrative review synthesizes current evidence on Optilume DCB specifically for BNS and VUAS. Materials and Methods: A comprehensive literature search identified eight relevant publications (2024–2026), including randomized controlled trials, prospective and retrospective cohort studies, and case series addressing Optilume DCB for posterior urethral stenoses. Results: Across the reviewed studies, freedom from reintervention for BNS ranged from 77.5% to 100% at 12 months, while VUAS outcomes were more variable (40–81%). A comparative study of 141 patients demonstrated significantly improved recurrence-free survival with DCB versus standard endoscopic treatment (HR 0.40, p = 0.021). Radiation-induced posterior urethral stenosis showed 81.1% freedom from repeat intervention. Complications were predominantly minor (Clavien-Dindo grade I), with no de novo incontinence attributable to the device. Conclusions: Optilume DCB represents a promising minimally invasive option for BNS and VUAS, particularly in patients with recurrent disease or those unsuitable for reconstructive surgery. BNS appears to respond more favorably than VUAS, likely reflecting distinct pathophysiological mechanisms. Prior radiation therapy remains a negative prognostic factor. Prospective randomized trials with longer follow-up are needed to define the role of DCB in posterior urethral stenosis management. Full article

Bilayer scattering films offer a practical route to independently controlling transmission and reflection in transparent optical systems, yet the separate roles of nanoparticle loading and stacking order remain underexplored. In this work, Al₂O₃/poly(methyl methacrylate) bilayer films with four concentration pairs (5/15, 15/5, 5/30, and 9/30 wt%) were fabricated by sequential spin-coating and characterized by wavelength-dependent transmittance, reflectance, integrating-sphere haze decomposition, and optical surface interferometry under both glass-side (G-incident) and scattering-layer-side (SL-incident) illumination. Two independent design parameters govern the optical response: (i) the maximum nanoparticle concentration sets the overall scattering regime, and (ii) the layer stacking order controls the partitioning between parallel transmittance (PT) and diffuse transmittance (DT). Bilayers with a maximum loading of 15 wt% maintained total transmittance (TT) ≈ 99% and moderate haze (25%–40%), while reciprocal 5/15 and 15/5 wt% pairs exhibited a ~15 percentage-point shift in PT despite identical total loading. Incorporation of a 30 wt% layer shifted films into a diffusion-dominant regime (DT > 68%, haze > 70%), and positioning this layer at the incident side under SL illumination suppressed visible reflectance below 1%. These results provide a practical composition–sequence design map for transparent optical coatings in display, privacy, and anti-glare applications. Full article

In this study, a non-typical luminescent organosilicone was synthesized through a click reaction and used as a cross-linker to cure hydroxyl-terminated dimethylsilicone oil at room temperature via the sol–gel process, followed by application as a coating on a glass surface. This organosilicone film functions effectively as a luminescent down-shifting (LDS) material. Additionally, the presence of methyl groups and voids in the structure imparts a low refractive index, allowing it to serve as an anti-reflective (AR) layer. Optical and structural analyses on organosilicone-coated glass samples were conducted, and the dual-functional layer was applied to the glass cover of a perovskite solar panel to evaluate its performance. The coating not only enhanced light transmission as an AR layer but also converted UV light into blue light, which was absorbed by the solar cell. The results indicated improved solar panel performance, particularly in short-circuit current (Isc), external quantum efficiency (EQE) in the UV wavelength range, and overall efficiency. Overall, this material is a promising candidate for solar panel applications owing to maximized UV absorption for LDS, preserved transparency of the top cover glass, and room-temperature gelation, which facilitates repair of the dual-functional coating. Full article

A compact, low-cost star tracker system tailored for small satellite applications was designed and prototyped. The system was designed with a fast f/1.2 aperture, a 20 × 13° field of view, and a theoretical angular resolution of 10 arcs—sufficient for the determination of attitude and orbit of a satellite. The optical design is based on a monolithic Maksutov–Cassegrain architecture, with lens assemblies fabricated from CR39 or PMMA to eliminate collimation requirements and improve vibration resistance. The lens was machined using Single-Point Diamond Turning to a precision better than λ/14. It was coated with a multilayer antireflective and highly reflective coatings applied via magnetron sputtering to reduce stray reflections and improve light throughput. The housing was produced using electron beam powder-bed fusion with Ti-64 alloy, while the use of commercial imaging sensors minimizes overall cost. Prototype testing confirmed to plate-solve star patterns with precision better than 27 arcs at 100 ms imaging time across all analysed images. Full article

Epoxy resin (E-51) exhibits excellent adhesion and is widely used in the preparation of functional composite coatings. However, its smooth surface lacking micro/nano composite structures limits its self-cleaning capability and optical properties. Direct incorporation of organic silicone or inorganic fillers often faces severe phase separation and filler agglomeration issues, resulting in defects in coating durability and weather resistance. To address these challenges, this study developed a synergistic modification strategy integrating surface energy modulation with the architectural design of micro/nano-structures. Amino-terminated PDMS undergoes ring-opening addition reactions with epoxy groups in the epoxy resin, while functionalized barium sulfate nanoparticles modified with dual silane coupling agents are incorporated to enhance optical properties. This synergistic approach not only resolved interfacial compatibility but also endowed the PDMS@EP-BaSO₄ coating with outstanding comprehensive properties; the water contact angle increased to 123.5°, demonstrating an easy-to-clean benefit. Visible light reflectance reached 95%, and emissivity rose to 90%. Furthermore, when applied to metal surfaces, the coating exhibited excellent stability against acid–alkali–salt corrosion, extreme temperatures, and ultrasonic agitation. This work provided a novel approach for developing protective coatings that integrated high reflectance, high emissivity, and long-term anti-soiling properties. Full article

The suppression of residual reflectivity in optical elements has become a hot research topic as it addresses the degradation of optical system imaging quality caused by stray light. Antireflective coatings on the outer surface of window glasses require low reflectivity, high hardness, and resistance to mechanical wear. This study investigates the role of reactive gas stoichiometry in tailoring the structure and performance of ${\mathrm{SiO}}_x$${\mathrm{N}}_y$ antireflection (AR) coatings deposited on GG7i glass via capacitively coupled radio-frequency magnetron sputtering. First, the influence of three ${\mathrm{N}}_2$/${\mathrm{O}}_2$ flow ratios on the optical and mechanical properties of ${\mathrm{SiO}}_x$${\mathrm{N}}_y$ films discussed under identical process parameters. Results show that the refractive index, hardness, and surface roughness of the ${\mathrm{SiO}}_x$${\mathrm{N}}_y$ films increase with increasing ${\mathrm{N}}_2$/${\mathrm{O}}_2$ ratio and that the stress of the ${\mathrm{SiO}}_x$${\mathrm{N}}_y$ films increases according to the Stoney formula. The wear resistance of the ${\mathrm{SiO}}_x$${\mathrm{N}}_y$ films combined with an antifingerprint (AF) coating is tested using steel wool. Experimental results show that the water contact angle of the AF decreases with increasing surface roughness of the film. Finally, on the basis of a comprehensive evaluation of optical and mechanical properties, the antireflection coating on the outer surface of the window glass was prepared by optimizing the process parameters. At $0^{°}$ incidence, the average reflectivity from 420 to 680 nm is <1%, the maximum value is <1.2%, the surface hardness is 17.2 GPa, and the water contact angle is ${100}^{°}$ after the steel wool wear test, showing its suitability for durable antifingerprint applications. This work provides a strategic pathway for designing high-performance optical coatings with tailored mechanical robustness. Full article

Interdigitated back-contact solar cells were fabricated entirely with inkjet printing. poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS), TiO₂, and metal lines were printed on a textured silicon substrate with only one inkjet printer. No vacuum deposition or diffusion of a back surface field is needed for the printed IBC solar cell. Adding co-solvent to the PEDOT:PSS and passivation of the Si surface significantly reduced the losses and enhanced the short-circuit current, Jsc, and, as a result, improved the fill factor and efficiency of the devices. The thickness of the PEDOT:PSS layer is approximately half a micrometer measured by profilometer, which is thicker than the optimal range typically reported; there is still a best short-circuit current, Jsc, of 19.2 mA/cm². To further improve the performance of the devices, an anti-reflective coating on the front side is required. Also, an improved metal contact ink is needed to improve the contact resistance between the PEDOT:PSS layer and the metal contact. The initial performance of all printed cells are compared to conventionally fabricated devices. Full article