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Review

160 Citations

22,506 Views

32 Pages

Sialyl-Tn in Cancer: (How) Did We Miss the Target?

Sylvain Julien,
Paula A. Videira and
Philippe Delannoy

Biomolecules2012, 2(4), 435-466;https://doi.org/10.3390/biom2040435

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11 October 2012

Sialyl-Tn antigen (STn) is a short O-glycan containing a sialic acid residue a2,6-linked to GalNAca-O-Ser/Thr. The biosynthesis of STn is mediated by a specific sialyltransferase termed ST6GalNAc I, which competes with O-glycans elongating glycosyltr...

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Review

8 Citations

5,074 Views

23 Pages

Fast Tracking—Vaccine Safety, Efficacy, and Lessons Learned: A Narrative Review

Jason C. Wong,
Crystal T. Lao,
Melanie M. Yousif and
Jacqueline M. Luga

Vaccines2022, 10(8), 1256;https://doi.org/10.3390/vaccines10081256

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4 August 2022

(1) Background: The COVID-19 pandemic has led to the fast-tracked development of vaccines under emergency use authorization. In light of the growing concerns about fast-tracked vaccines, this article reviews the safety, efficacy, and lessons learned...

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