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Article

1,876 Views

19 Pages

A Structural Proteomics Exploration of Synphilin-1 and Alpha-Synuclein Interaction in Pathogenesis of Parkinson’s Disease

Asmita Tripathi,
Rajkrishna Mondal,
Malay Mandal,
Tapobrata Lahiri and
Manoj Kumar Pal

Biomolecules2024, 14(12), 1588;https://doi.org/10.3390/biom14121588

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12 December 2024

Pathological significance of interaction of Synphilin-1 with mutated alpha-synuclein is well known to have serious consequences in causing the formation of inclusion bodies that are linked to Parkinson’s disease (PD). Information extracted so f...

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Article

16 Citations

5,898 Views

9 Pages

Hypermethylation of Synphilin-1, Alpha-Synuclein-Interacting Protein (SNCAIP) Gene in the Cerebral Cortex of Patients with Sporadic Parkinson’s Disease

Khashayar Dashtipour,
Ali Tafreshi,
Charles Adler,
Thomas Beach,
Xin Chen,
Geidy Serrano,
Stephanie Tashiro and
Charles Wang

Brain Sci.2017, 7(7), 74;https://doi.org/10.3390/brainsci7070074

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27 June 2017

Objective: To determine and compare DNA methylation patterns between patients with Parkinson’s disease (PD) and age- and sex-similar matched non-PD controls. Background: Epigenetic regulation is one of the major mechanisms for an organism to respond...

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