Neovascular age-related macular degeneration (nAMD) with choroidal neovascularization (CNV) is a leading cause of blindness in the elderly in developed countries. The disease is currently treated with anti-angiogenic biologics, including aflibercept,...
Secretogranin III (Scg3) is a diabetic retinopathy (DR)-restricted angiogenic factor identified in preclinical studies as a target for DR therapy. Previously, our group generated and characterized ML49.3, an anti-Scg3 monoclonal antibody (mAb) which...
The retinopathy of prematurity (ROP), a neovascular retinal disorder presenting in premature infants, is the leading causes of blindness in children. Currently, there is no approved drug therapy for ROP in the U.S., highlighting the urgent unmet clin...
The physical properties of sodium cocoyl glycinate (SCG) and the synergistic effects within the SCG/CAPB complex system were investigated using visible–ultraviolet spectrophotometry and a surface tension meter. Analysis of the synergistic param...
Cardiovascular disease (CVD) is a major public concern and socioeconomic problem across the globe. The popular high-end cardiac health monitoring systems such as magnetic resonance imaging (MRI), computerized tomography scan (CT scan), and echocardio...
Robots need to sense information about the external environment before moving, which helps them to recognize and understand their surroundings so that they can plan safe and effective paths and avoid obstacles. Conventional algorithms using a single...
The aim of this study was to investigate and compare the effects of different extraction techniques (high hydrostatic pressure-assisted extraction (HHPE), ultrasound-assisted extraction (UAE), and classical solvent extraction (CSE)) on phenolic compo...
Use of information and communication technology such as smart phone, smart watch, smart glass and portable health monitoring devices for healthcare services has made Mobile Health (mHealth) an emerging research area. Coronary Heart Disease (CHD) is c...
The growing demand for sustainable materials in a circular economy necessitates the evaluation of the recyclability of biodegradable composites. This study aims to investigate the effect of multiple mechanical recycling cycles on the properties of a...
In recent years, cardiovascular diseases are on the rise, and they entail enormous health burdens on global economies. Cardiac vibrations yield a wide and rich spectrum of essential information regarding the functioning of the heart, and thus it is n...
Since the time when detection of gene expression in single cells by microarrays to the Next Generation Sequencing (NGS) enabled Single Cell Genomics (SCG), it has played a pivotal role to understand and elucidate the functional role of cellular heter...
This paper presents a novel adaptive recursive least squares filter (ARLSF) for motion artifact removal in the field of seismocardiography (SCG). This algorithm was tested with a consumer-grade accelerometer. This accelerometer was placed on the ches...
Spent coffee grounds (SCG) have potential as a sustainable bio-filler in poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) composites, offering an environmentally friendly approach to waste utilization. This study investigated the effect of SCG con...
Karst caves host most European Paleolithic sites. Near the Eurasian-Arabian Plate convergence in the Caucasus’ Lower Chegem Formation, Saradj-Chuko Grotto (SCG), a lava tube, contains 16 geoarchaeologically distinct horizons yielding modern to...
Diabetic retinopathy (DR), a leading cause of vision loss in working-age adults, induces mosaic patterns of vasculopathy that may be associated with spatial heterogeneity of intraretinal endothelial cells. We recently reported that secretogranin III...
A new simpler coarse-grain model (SCG) for analyzing particle behaviors under fluid flow in a dilute system, by using a discrete element method (DEM), was developed to reduce calculation load. In the SCG model, coarse-grained (CG) particles were enla...
We developed ligandomics for the in vivo profiling of vascular ligands in mice, discovering secretogranin III (Scg3) as a novel angiogenic factor that selectively binds to retinal vessels of diabetic but not healthy mice. This discovery led to the de...
Continuous cardiac monitoring has been developed to evaluate cardiac activity outside of clinical environments due to the advancement of novel instruments. Seismocardiography (SCG) is one of the vital components that could develop such a monitoring s...
Spent coffee grounds (SCGs) are a food waste with a large generation around the world. However, their utilization as a soil organic amendment is difficult due to their phytotoxic effect. In the present work, the impact of agronomic biofortification o...
Coffee is one of the most popular and consumed products in the world, generating tons of solid waste known as spent coffee grounds (SCG), containing several bioactive compounds. Here, the antifungal activity of ethanolic SCG extract from caffeinated...
Spent coffee grounds (SCG) are industrial biowaste resulting from the coffee-brewing process, and they are often underutilized and end up in landfills, thereby leading to the emission of toxic gases and environmental damage. Hydrothermal carbonizatio...
This work investigated the addition of spent coffee grounds (SCG) as a valuable resource to produce biocomposites based on polylactic acid (PLA). PLA has a positive biodegradation effect but generates poor proprieties, depending on its molecular stru...
Continuous cardiovascular monitoring is essential for the early detection of cardiac events, but conventional electrode-based ECG systems cause skin irritation and are unsuitable for long-term wear. We propose an electrode-free ECG monitoring approac...
(1) Background: The botulinum toxin A (BoNT-A) heavy chain (HC) can stimulate the growth of primary motor neurites. (2) Methods: A recombinant BoNT/A HC was injected locally plus interval intrathecal catheter of BoNT/A HC to rats with ipsilateral sem...
This article introduces a new way of using a fibre Bragg grating (FBG) sensor for detecting the presence and number of occupants in the monitored space in a smart home (SH). CO2 sensors are used to determine the CO2 concentration of the monitored roo...
This work presents a methodology to analyze and segment both seismocardiogram (SCG) and ballistocardiogram (BCG) signals in a unified fashion. An unsupervised approach is followed to extract a template of SCG/BCG heartbeats, which is then used to fin...
As a unique electric-optics material, liquid crystals (LCs) have been used in various light-control applications. In LC-based light-control devices, the structural alignment of LC molecules is of great significance. Generally, additional alignment la...
In this paper, the Levenberg–Marquardt (LM), Bayesian regularization (BR), resilient backpropagation (RP), gradient descent momentum (GDM), Broyden–Fletcher–Goldfarb–Shanno (BFGS), and scaled conjugate gradient (SCG) algorithm...
Currently composites play an important role in all aspects of engineering and technology, with constantly growing applications. Recently, more attention was focused on natural fillers due to their suitability as reinforcement materials in thermo-plas...
Quartz is a widely used mineral in dosimetric and geochronological applications due to its stable luminescence properties under ionizing radiation. This study presents an artificial neural network (ANN)-based approach to predict the optically stimula...
Cardiac activity has been monitored continuously in daily life by virtue of advanced medical instruments with microelectromechanical system (MEMS) technology. Seismocardiography (SCG) has been considered to be free from the burden of measurement for...
Spent coffee grounds (SCGs), one of the world’s most discarded wastes, may be an excellent resource as an organic fertilizer because of its richness in nutrients. The objective of this study was to develop a quality functional compost using SCGs, ric...
This paper presents an unsupervised methodology to analyze SeismoCardioGram (SCG) signals. Starting from raw accelerometric data, heartbeat complexes are extracted and annotated, using a two-step procedure. An unsupervised calibration procedure is ad...
Retinopathy of prematurity (ROP) is an ocular vascular disease affecting premature infants, characterized by pathological retinal neovascularization (RNV), dilated and tortuous retinal blood vessels, and retinal or vitreous hemorrhages that may lead...
Carbon-based materials have become an indispensable component in a myriad of domestic and industrial applications. Most of the carbon-based end-of-life products discussed in this review end up in landfills. Where recycling is available, it usually in...
As the consumption of coffee increases worldwide, the amount of spent coffee grounds (SCG) is gradually increasing every year. Some of these grounds are recycled for composting, but most are discarded, which causes widespread financial and social cos...
Spent coffee grounds (SCGs) generated in coffee processing for beverages and other products are a very significant organic residue that needs to be properly treated. Waste valorization via oil extraction has the potential to obtain compounds that can...
This study presents the thermodynamic modelling of hydrogen production from autothermal reforming of synthetic crude glycerol using the Peng-Robinson Stryjek-Vera thermodynamic model and Gibbs free energy minimization approach. In order to simulate t...
This study introduces a mechatronic biomedical device engineered for concurrent acquisition and analysis of four cardiac non-invasive signals: Electrocardiogram (ECG), Phonocardiogram (PCG), Impedance Cardiogram (ICG), and Photoplethysmogram (PPG). T...
Coffee is one of the most consumed and popular beverages worldwide, and it produces a significant quantity of waste. Spent coffee grounds (SCGs) are one of the major waste products that can be used as an ingredient for creating novel foods. Therefore...
The unsustainability of current and future agricultural use has led to increased interest in using organic waste products, such as spent coffee grounds (SCGs) and compost, as alternative nutrient supplements. While SCGs are initially phytotoxic, upon...
Coffee is considered to be one of the most renowned beverages and it is the second-most consumed product worldwide. Spent coffee grounds (SCGs) are the primary solid residue, which are generated during the coffee powder brewing in hot water or steam....
The superior cervical ganglion (SCG) is part of the autonomic nervous system providing sympathetic innervation to the head and neck, and has been regularly used to prepare postnatal neuronal cultures for cell biological studies. We found that during...
Spent coffee grounds (SCGs) are a by-product of the food industry which contain a rich source of polysaccharides. This research was to study the extraction of polysaccharides from SCGs by environmentally friendly technic of pressurized hot water. The...
The Zoanthids are an order of cnidarians whose venoms and toxins have been poorly studied. Palythoa caribaeorum is a zoanthid commonly found around the Mexican coastline. In this study, we tested the activity of P. caribaeorum venom on voltage-gated...
This article presents the results of a study on metallurgical slag reduction using biomass such as Spent Coffee Grounds (SCGs). The proposed solution is a new aspect of searching for alternatives to standard reducers used in pyrometallurgical process...
Existing studies have attempted to determine the tool chipping condition using the indirect method of data capture and intelligent analysis techniques considering machine parameters, and tool conditions using signal processing techniques. Due to the...
Frequency estimation plays a critical role in vital sign monitoring. Methods based on Fourier transform and eigen-analysis are commonly adopted techniques for frequency estimation. Because of the nonstationary and time-varying characteristics of phys...
The current status of the research of Ballistocardiography (BCG) and Seismocardiogram (SCG) in the field of medical treatment, health care and nursing was analyzed systematically, and the important direction in the research was explored, to provide r...
Evaporation is one of the main components of the hydrological cycle, and its estimation is crucial and important for water resources management issues. Access to a reliable estimator tool for evaporation simulation is important in arid and semi-arid...
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