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  • Review
  • Open Access
4,004 Views
18 Pages

Aging and Thymosin Alpha-1

  • Maria A. Simonova,
  • Igor Ivanov,
  • Natalia S. Shoshina,
  • Alina M. Komyakova,
  • Dmitry A. Makarov,
  • Denis S. Baranovskii,
  • Ilya D. Klabukov,
  • Kristina P. Telepenina,
  • Dmitrii A. Atiakshin and
  • Vasiliy N. Stepanenko
  • + 2 authors

27 November 2025

Aging is characterized by immune decline, mainly due to thymic involution—the age-related shrinkage of the thymus gland. This leads to reduced T-cell production, chronic inflammation, and increased susceptibility to age-related diseases. Thymos...