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299 Results Found

  • Article
  • Open Access
11 Citations
2,992 Views
31 Pages

6 September 2024

The trajectory estimation of a highly maneuvering target is a challenging problem and has practical applications. The interacting multiple model (IMM) filter is a well-established filtering algorithm for the trajectory estimation of maneuvering targe...

  • Article
  • Open Access
21 Citations
4,007 Views
25 Pages

28 November 2020

High accuracy and reliable navigation in the underwater environment is very critical for the operations of autonomous underwater vehicles (AUVs). This paper proposes an adaptive federated interacting multiple model (IMM) filter, which combines adapti...

  • Article
  • Open Access
13 Citations
4,712 Views
26 Pages

28 September 2017

Aimed at solving the problem of decreased filtering precision while maneuvering target tracking caused by non-Gaussian distribution and sensor faults, we developed an efficient interacting multiple model-unscented Kalman filter (IMM-UKF) algorithm. B...

  • Article
  • Open Access
18 Citations
4,431 Views
28 Pages

IMM-H004 Protects against Cerebral Ischemia Injury and Cardiopulmonary Complications via CKLF1 Mediated Inflammation Pathway in Adult and Aged Rats

  • Qidi Ai,
  • Chen Chen,
  • Shifeng Chu,
  • Yun Luo,
  • Zhao Zhang,
  • Shuai Zhang,
  • Pengfei Yang,
  • Yan Gao,
  • Xiaoling Zhang and
  • Naihong Chen

(1) Background: Chemokine-like factor 1 (CKLF1) is a chemokine with potential to be a target for stroke therapy. Compound IMM-H004 is a novel coumarin derivative screened from a CKLF1/C-C chemokine receptor type 4 (CCR4) system and has been reported...

  • Article
  • Open Access
684 Views
18 Pages

Distributed Diffusion Multi-Distribution Filter with IMM for Heavy-Tailed Noise

  • Guannan Chang,
  • Changwu Jiang,
  • Wenxing Fu,
  • Tao Cui and
  • Peng Dong

1 August 2025

With the diversification of space applications, the tracking of maneuvering targets has gradually gained attention. Issues such as their wide range of movement and observation outliers caused by human operation are worthy of in-depth discussion. This...

  • Article
  • Open Access
39 Citations
6,939 Views
17 Pages

5 September 2017

Inertial navigation system (INS)/Doppler velocity log (DVL) integration is the most common navigation solution for underwater vehicles. Due to the complex underwater environment, the velocity information provided by DVL always contains some errors. T...

  • Article
  • Open Access
2 Citations
3,207 Views
21 Pages

4 September 2020

For radar systems with low update rates; such as track-while-scan (TWS) systems using rotating phased array antennas; reducing the prediction error is a very important issue. A good interacting multiple models (IMM) hybrid filter combined with circul...

  • Article
  • Open Access
2,192 Views
13 Pages

Assessment of the Purity of IMM-H014 and Its Related Substances for the Treatment of Metabolic-Associated Fatty Liver Disease Using Quantitative Nuclear Magnetic Resonance Spectroscopy

  • Hanyilan Zhang,
  • Haowen Zhu,
  • Song Wu,
  • Haoyang Tang,
  • Wenxuan Zhang,
  • Xiaoliang Gong,
  • Tiesong Wang,
  • Yinghong Wang and
  • Qingyun Yang

15 December 2023

An accurate, rapid, and selective quantitative nuclear magnetic resonance method was developed and validated to assess the purity of IMM-H014, a novel drug for the treatment of metabolic-associated fatty liver disease (MAFLD), and four related substa...

  • Communication
  • Open Access
5 Citations
2,616 Views
8 Pages

10 February 2023

The shortening of the minority carrier lifetime is the main reason for the degradation of the electrical performance of solar cells; therefore, it is particularly important to evaluate the minority carrier lifetime of inverted metamorphic triple junc...

  • Article
  • Open Access
535 Views
20 Pages

18 November 2025

Multi-object tracking (MOT) is a critical task in computer vision, with widespread applications in intelligent surveillance, behavior analysis, autonomous navigation, and marine ecological monitoring. In particular, accurate tracking of underwater fi...

  • Article
  • Open Access
2 Citations
2,331 Views
15 Pages

Development and In Vitro–In Vivo Correlation Evaluation of IMM-H014 Extended-Release Tablets for the Treatment of Fatty Liver Disease

  • Chi Zhang,
  • Huihui Shao,
  • Zunsheng Han,
  • Bo Liu,
  • Jing Feng,
  • Jie Zhang,
  • Wenxuan Zhang,
  • Kun Zhang,
  • Qingyun Yang and
  • Song Wu

2 August 2023

This study aimed to develop extended-release tablets containing 25 mg IMM-H014, an original drug formulated by a direct powder pressing method based on pharmaceutical-grade hydrophilic matrix polymers such as hydroxypropyl methylcellulose, to establi...

  • Article
  • Open Access
3,365 Views
21 Pages

28 August 2025

This study applies the Integrated Modification Methodology (IMM) to assess how morphology-driven, nature-based solutions reduce urban heat island (UHI) effects and flooding in Rio de Janeiro’s Cidade Nova. Multi-scale GIS diagnostics identify g...

  • Article
  • Open Access
577 Views
21 Pages

17 November 2025

The rapid increase in global vehicle usage has intensified challenges such as traffic congestion, frequent accidents, and energy consumption, highlighting the need for safe and efficient platooning strategies. Conventional adaptive cruise control (AC...

  • Article
  • Open Access
8 Citations
2,507 Views
18 Pages

Improvement in the Tracking Performance of a Maneuvering Target in the Presence of Clutter

  • Ghawas Ali Shah,
  • Sumair Khan,
  • Sufyan Ali Memon,
  • Mohsin Shahzad,
  • Zahid Mahmood and
  • Uzair Khan

16 October 2022

The proposed work uses fixed lag smoothing on the interactive multiple model-integrated probabilistic data association algorithm (IMM-IPDA) to enhance its performance. This approach makes use of the advantages of the fixed lag smoothing algorithm to...

  • Article
  • Open Access
10 Citations
2,841 Views
22 Pages

Interacting Multiple Model Estimators for Fault Detection in a Magnetorheological Damper

  • Andrew Sanghyun Lee,
  • Yuandi Wu,
  • Stephen Andrew Gadsden and
  • Mohammad AlShabi

31 December 2023

This paper proposes a novel estimator for the purpose of fault detection and diagnosis. The interacting multiple model (IMM) strategy is effective for estimating the behaviour of systems with multiple operating modes. Each mode corresponds to a disti...

  • Article
  • Open Access
9 Citations
5,386 Views
9 Pages

Diagnostic and Therapeutic Pathways of Intramuscular Myxoma

  • Alonja Reiter,
  • Katharina Trumm,
  • Tobias M. Ballhause,
  • Sebastian Weiss,
  • Karl-Heinz Frosch,
  • Alexander Korthaus,
  • Ulrich Bechler,
  • Anna Duprée,
  • Andreas Luebke and
  • Matthias H. Priemel
  • + 2 authors

Intramuscular myxomas (IMMs) are benign tumors. Evidence regarding diagnostic and therapeutic pathways is rare, and guidelines do not exist due to their low incidence. The aim of this study was a retrospective analysis at a university cancer center a...

  • Article
  • Open Access
2 Citations
3,843 Views
12 Pages

Highly Efficient Synthesis of 2,5-Dihydroxypyridine using Pseudomonas sp. ZZ-5 Nicotine Hydroxylase Immobilized on Immobead 150

  • Caiwen Dong,
  • Yadong Zheng,
  • Hongzhi Tang,
  • Zhangde Long,
  • Jigang Li,
  • Zhiping Zhang,
  • Sumeng Liu,
  • Duobin Mao and
  • Tao Wei

16 November 2018

In this report, the use of immobilized nicotine hydroxylase from Pseudomonas sp. ZZ-5 (HSPHZZ) for the production of 2,5-dihydroxypyridine (2,5-DHP) from 6-hydroxy-3-succinoylpyridine (HSP) in the presence of nicotinamide adenine dinucleotide (NADH)...

  • Article
  • Open Access
1,411 Views
28 Pages

3 December 2024

In this paper, in order to enhance the autonomous operation capabilities of aircraft and ensure their operational safety and efficiency, we propose an autonomous decision-making framework based on target motion state prediction combined with the Mark...

  • Article
  • Open Access
1 Citations
869 Views
18 Pages

Inflammatory Bowel Disease Patients with a History of Cancer: Safety of Immunomodulators in a Multicenter Study

  • Roberto Mancone,
  • Benedetto Neri,
  • Clara De Francesco,
  • Livio Bonacci,
  • Mariasofia Fiorillo,
  • Sara Concetta Schiavone,
  • Anna Galbusera,
  • Alba Sparacino,
  • Anna Testa and
  • Livia Biancone
  • + 7 authors

11 October 2025

Introduction: The risk of new or recurrent cancer in inflammatory bowel disease (IBD) patients with a history of cancer treated with immunomodulators (IMMs), including conventional immunosuppressors (ISSs), biologics or small molecules is undefined....

  • Article
  • Open Access
8 Citations
3,708 Views
8 Pages

6 May 2022

Inverted metamorphic triple junction (IMM3J) GaInP/GaAs/InGaAs solar cells have the advantages of high efficiency, excellent radiation resistance, lightweight and flexible properties, especially suitable for space application. In this paper, we first...

  • Review
  • Open Access
27 Citations
5,955 Views
17 Pages

7 October 2018

Carbohydrate analyses are often challenging due to the structural complexity of these molecules, as well as the lack of suitable analytical tools for distinguishing the vast number of possible isomers. The coupled technique, ion mobility-mass spectro...

  • Article
  • Open Access
2 Citations
2,131 Views
21 Pages

Precise and real-time estimation of vehicle mass and road slope plays a pivotal role in attaining accurate vehicle control. Currently, road slope estimation predominantly emphasizes longitudinal slopes, with limited research on intricate slopes that...

  • Article
  • Open Access
14 Citations
3,686 Views
20 Pages

6 November 2019

In maneuvering target tracking applications, the performance of the traditional interacting multiple model (IMM) filter deteriorates seriously under heavy-tailed measurement noises which are induced by outliers. A robust IMM filter utilizing Student&...

  • Article
  • Open Access
28 Citations
10,510 Views
16 Pages

27 March 2013

The International Civil Aviation Organization (ICAO) has decided to adopt Communications, Navigation, and Surveillance/Air Traffic Management (CNS/ATM) as the 21st century standard for navigation. Accordingly, ICAO members have provided an impetus to...

  • Article
  • Open Access
11 Citations
5,028 Views
19 Pages

Autonomous drones offer immense potential in dynamic environments, but their navigation systems often struggle with moving obstacles. This paper presents a novel approach for drone trajectory planning in such scenarios, combining the Interactive Mult...

  • Article
  • Open Access
3 Citations
2,810 Views
25 Pages

Three-Dimensional Multi-Target Tracking Using Dual-Orthogonal Baseline Interferometric Radar

  • Saima Ishtiaq,
  • Xiangrong Wang,
  • Shahid Hassan,
  • Alsharef Mohammad,
  • Ahmad Aziz Alahmadi and
  • Nasim Ullah

5 October 2022

Multi-target tracking (MTT) generally needs either a Doppler radar network with spatially separated receivers or a single radar equipped with costly phased array antennas. However, Doppler radar networks have high computational complexity, attributed...

  • Article
  • Open Access
6 Citations
4,866 Views
24 Pages

16 August 2021

Multi-target tracking (MTT) generally requires either a network of Doppler radar receivers distributed at different locations or a phased array radar. The targets moving with small/no radial velocity or angular velocity only cannot be detected and lo...

  • Article
  • Open Access
7 Citations
4,989 Views
26 Pages

Transit-Oriented Development in Middle Eastern Cities: The Urban Renewal Framework for the Souq Waqif in Doha, Qatar

  • Tagwa A. A. Osman,
  • Tarryn N. K. Paquet,
  • Raffaello Furlan,
  • Massimo Tadi,
  • Rashid Saad Al-Matwi and
  • Rima J. Isaifan

21 October 2024

Cities around the world are evolving dramatically due to urbanization. Over the last few decades, rapid urbanization coupled with rapid economic growth in Qatar has resulted in transport-related issues such as urban sprawl, traffic congestion, poor w...

  • Article
  • Open Access
1,524 Views
39 Pages

UIMM-Tracker: IMM-Based with Uncertainty Detection for Video Satellite Infrared Small-Target Tracking

  • Yuanxin Huang,
  • Xiyang Zhi,
  • Zhichao Xu,
  • Wenbin Chen,
  • Qichao Han,
  • Jianming Hu,
  • Yi Sui and
  • Wei Zhang

14 June 2025

Infrared video satellites have the characteristics of wide-area long-duration surveillance, enabling continuous operation day and night compared to visible light imaging methods. Therefore, they are widely used for continuous monitoring and tracking...

  • Review
  • Open Access
1,019 Views
20 Pages

Ion Mobility–Mass Spectrometry Imaging: Advances in Biomedical Research

  • Mengya Liu,
  • Chi Zhang,
  • Lili Xu,
  • Md. Muedur Rahman,
  • Shoshiro Hirayama,
  • Shuhei Aramaki,
  • Atsushi Baba,
  • Ryo Omagari,
  • Yutaka Takahashi and
  • Mitsutoshi Setou
  • + 1 author

18 December 2025

Mass spectrometry imaging (MSI) visualizes the spatial distribution of biomolecules in tissues, whereas ion mobility–mass spectrometry (IM-MS) separates ions through the collision cross-section (CCS) with an inert gas, providing the structural...

  • Article
  • Open Access
12 Citations
2,827 Views
23 Pages

15 March 2024

A pulse-Doppler (PD) radar has the advantage of strong anti-interference ability, and it is often used as a solution for maneuvering target tracking. In the application of target monitoring and tracking in PD radars, the interacting multiple model al...

  • Article
  • Open Access
12 Citations
3,865 Views
22 Pages

26 May 2021

For mass application positioning demands, the current single positioning sensor cannot provide reliable and accurate positioning. Herein, we present batch inverse covariance intersection (BICI) and BICI with interacting multiple model (BICI-IMM) mult...

  • Article
  • Open Access
5 Citations
5,444 Views
22 Pages

OntoIMM: An Ontology for Product Intelligent Master Model

  • Cong Yu,
  • Fa-ping Zhang,
  • Shahid I. Butt,
  • Yan Yan and
  • Wu Lv

22 June 2019

Information organizing principle is one of the key issues of intelligent master model (IMM), which is an enhancement of the master model (MM) based on KBE (knowledge-based engineering). Despite the fact that the core product model (CPM) has been conf...

  • Article
  • Open Access
6 Citations
1,511 Views
20 Pages

State Parameter Fusion Estimation for Intelligent Vehicles Based on IMM-MCCKF

  • Qi Chen,
  • Feng Zhang,
  • Liang Su,
  • Baoxing Lin,
  • Sien Chen and
  • Yong Zhang

24 May 2024

The prerequisite for intelligent vehicles to achieve autonomous driving and active safety functions is acquiring accurate vehicle state parameters. Traditional Kalman filters often underperform in non-Gaussian noise environments due to their reliance...

  • Article
  • Open Access
2 Citations
1,738 Views
17 Pages

26 November 2021

This paper newly proposes an interactive multiple model (IMM) algorithm to adaptively track distorted AC voltage with the grid frequency fluctuation. The usual tracking methods are Kalman filter (KF) algorithm with a fixed frequency and KF algorithm...

  • Article
  • Open Access
10 Citations
3,937 Views
13 Pages

Estimation of Vehicle State Based on IMM-AUKF

  • Ying Xu,
  • Wenjie Zhang,
  • Wentao Tang,
  • Chengxiang Liu,
  • Rong Yang,
  • Li He and
  • Yun Wang

24 January 2022

Establishing a symmetrical model of surrounding vehicles and accurately obtaining the driving state of the surrounding vehicles in the driving environment can improve the safety of driving, which is an important issue that needs to be considered in t...

  • Article
  • Open Access
4 Citations
3,201 Views
21 Pages

Background: Glucuronidation is an essential metabolic pathway for a variety of drugs. IMM-H004 is a novel neuroprotective agent against ischemic stroke, and its glucuronide metabolite IMM-H004G exhibits similar pharmacological activity. Despite posse...

  • Article
  • Open Access
6 Citations
2,771 Views
16 Pages

26 November 2021

The multirotor has the capability to capture distant objects. Because the computing resources of the multirotor are limited, efficiency is an important factor to consider. In this paper, multiple target tracking with a multirotor at a long distance (...

  • Article
  • Open Access
4 Citations
1,079 Views
20 Pages

18 June 2025

Airborne radar-based ground moving target tracking faces challenges such as low detection rates and high clutter density. While lowering the detection threshold can improve detection performance, it introduces significant false alarms, thereby degrad...

  • Article
  • Open Access
29 Citations
4,536 Views
28 Pages

27 May 2020

Cooperative standoff tracking of moving targets is an important application of fixed-wing unmanned aerial vehicles (UAVs). To cope with the problem of long convergence time and unstable tracking in cooperative target tracking, traditional Lyapunov ve...

  • Article
  • Open Access
6 Citations
2,570 Views
23 Pages

A proper filtering method for jump Markov system (JMS) is an effective approach for tracking a maneuvering target. Since the coexisting of heavy-tailed measurement noises (HTMNs) and one-step random measurement delay (OSRMD) in the complex scenarios...

  • Article
  • Open Access
9 Citations
3,492 Views
16 Pages

26 November 2021

Recently, technology utilizing ultra-wideband (UWB) sensors for robot localization in an indoor environment where the global navigation satellite system (GNSS) cannot be used has begun to be actively studied. UWB-based positioning has the advantage o...

  • Article
  • Open Access
3 Citations
2,871 Views
17 Pages

Mass Spectrometry, Ion Mobility Separation and Molecular Modelling: A Powerful Combination for the Structural Characterisation of Substituted Cyclodextrins Mixtures

  • Sébastien Rigaud,
  • Abdouramane Dosso,
  • David Lesur,
  • Dominique Cailleu,
  • David Mathiron,
  • Serge Pilard,
  • Christine Cézard and
  • Florence Djedaini-Pilard

1 November 2022

When working on the synthesis of substituted cyclodextrins (CDs), the main challenge remains the analysis of the reaction media content. Our objective in this study was to fully characterise a complex isomers mixture of Lipidyl-βCDs (LipβCD...

  • Article
  • Open Access
2,607 Views
23 Pages

A suitable jump Markov system (JMS) filtering approach provides an efficient technique for tracking surface targets. In complex surface target tracking situations, due to the joint influences of lost measurements with an unknown probability and heavy...

  • Review
  • Open Access
129 Citations
21,288 Views
16 Pages

Tebentafusp: T Cell Redirection for the Treatment of Metastatic Uveal Melanoma

  • Bertil E. Damato,
  • Joseph Dukes,
  • Howard Goodall and
  • Richard D. Carvajal

11 July 2019

Metastatic disease from uveal melanoma occurs in almost 50% of patients suffering from this ocular tumour, with median survival from development of symptoms being around 1 year. In contrast to cutaneous melanoma, kinase inhibitors and immune checkpoi...

  • Article
  • Open Access
4 Citations
2,421 Views
17 Pages

29 May 2022

With the continuous development of wireless sensor network (WSN) technology, WSN has gradually become one of the key technologies of the Internet, and is widely used in indoor target location technology. However, the obstacles will have a great influ...

  • Article
  • Open Access
2 Citations
1,616 Views
26 Pages

Tracking Extended Targets: Novel TPMB Filter Driven by Model and Data Collaboration

  • Yubin Zhou,
  • Bo Li,
  • Jinyu Zhang,
  • Zhikang Li and
  • Zhengyuan Li

16 August 2024

In most filtering algorithms involving measurement data association, handling the complex computations due to multiple hypotheses is necessary. This paper introduces a novel Trajectory Poisson Multi-Bernoulli (TPMB) filter for tracking extended targe...

  • Article
  • Open Access
213 Views
25 Pages

29 January 2026

Orbit determination for non-cooperative targets represents a significant focus of research within the domain of space situational awareness. In contrast to cooperative targets, non-cooperative targets do not provide their orbital parameters, necessit...

  • Article
  • Open Access
86 Citations
13,355 Views
23 Pages

Design, Calibration, and Evaluation of a Backpack Indoor Mobile Mapping System

  • Samer Karam,
  • George Vosselman,
  • Michael Peter,
  • Siavash Hosseinyalamdary and
  • Ville Lehtola

13 April 2019

Indoor mobile mapping systems are important for a wide range of applications starting from disaster management to straightforward indoor navigation. This paper presents the design and performance of a low-cost backpack indoor mobile mapping system (I...

  • Article
  • Open Access
5 Citations
1,766 Views
23 Pages

10 February 2025

In complex environments, traditional multi-target tracking methods often encounter challenges such as strong clutter interference and interruptions in target trajectories, which can result in insufficient tracking accuracy and robustness. To address...

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