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25 Results Found

  • Article
  • Open Access
6 Citations
3,002 Views
23 Pages

Development of Bi- and Tri-Layer Nanofibrous Membranes Based on the Sulfated Polysaccharide Carrageenan for Periodontal Tissue Regeneration

  • Stefanos Kikionis,
  • Konstantina Iliou,
  • Aikaterini G. Karra,
  • Georgios Polychronis,
  • Ioannis Choinopoulos,
  • Hermis Iatrou,
  • George Eliades,
  • Efthymia Kitraki,
  • Ioulia Tseti and
  • Vassilios Roussis
  • + 2 authors

28 October 2023

Periodontitis is a microbially-induced inflammation of the periodontium that is characterized by the destruction of the periodontal ligament (PDL) and alveolar bone and constitutes the principal cause of teeth loss in adults. Periodontal tissue regen...

  • Article
  • Open Access
43 Citations
5,376 Views
24 Pages

Polymer Membranes Sonocoated and Electrosprayed with Nano-Hydroxyapatite for Periodontal Tissues Regeneration

  • Julia Higuchi,
  • Giuseppino Fortunato,
  • Bartosz Woźniak,
  • Agnieszka Chodara,
  • Sebastian Domaschke,
  • Sylwia Męczyńska-Wielgosz,
  • Marcin Kruszewski,
  • Alex Dommann and
  • Witold Łojkowski

15 November 2019

Diseases of periodontal tissues are a considerable clinical problem, connected with inflammatory processes and bone loss. The healing process often requires reconstruction of lost bone in the periodontal area. For that purpose, various membranes are...

  • Article
  • Open Access
10 Citations
2,523 Views
14 Pages

Our objective was to determine and optimize the significant parameters affecting mechanical properties and mean fiber diameter (MFD) of a novel GTR/GBR membrane composed of polycaprolactone (PCL) and chicken eggshell membrane (ESM). For this, we prep...

  • Review
  • Open Access
298 Citations
26,631 Views
20 Pages

Biodegradable Polymer Membranes Applied in Guided Bone/Tissue Regeneration: A Review

  • Jiaolong Wang,
  • Lina Wang,
  • Ziyu Zhou,
  • Hanjian Lai,
  • Pan Xu,
  • Lan Liao and
  • Junchao Wei

29 March 2016

Polymer membranes have been widely used in guided tissue regeneration (GTR) and guided bone regeneration (GBR). In this review, various commercially available membranes are described. Much attention is paid to the recent development of biodegradable...

  • Article
  • Open Access
1 Citations
968 Views
20 Pages

Preparation and Characterization of Novel Nanofibrous Composites Prepared by Electrospinning as Multifunctional Platforms for Guided Bone Regeneration Procedures

  • Aleksandra Sierakowska-Byczek,
  • Julia Radwan-Pragłowska,
  • Łukasz Janus,
  • Tomasz Galek,
  • Natalia Radwan-Pragłowska,
  • Karol Łysiak,
  • Piotr Radomski and
  • Mirosław Tupaj

27 February 2025

Prosthetics, a rapidly advancing field in dentistry, aims to improve patient comfort and aesthetics by addressing the challenge of replacing missing teeth. A critical obstacle in dental implantation is the condition of the jawbone, which often necess...

  • Article
  • Open Access
50 Citations
6,977 Views
22 Pages

Degradation, Bone Regeneration and Tissue Response of an Innovative Volume Stable Magnesium-Supported GBR/GTR Barrier Membrane

  • Mike Barbeck,
  • Lennart Kühnel,
  • Frank Witte,
  • Jens Pissarek,
  • Clarissa Precht,
  • Xin Xiong,
  • Rumen Krastev,
  • Nils Wegner,
  • Frank Walther and
  • Ole Jung

Introduction: Bioresorbable collagenous barrier membranes are used to prevent premature soft tissue ingrowth and to allow bone regeneration. For volume stable indications, only non-absorbable synthetic materials are available. This study investigates...

  • Review
  • Open Access
63 Citations
8,877 Views
23 Pages

Advances in Modification Methods Based on Biodegradable Membranes in Guided Bone/Tissue Regeneration: A Review

  • Yue Gao,
  • Shuai Wang,
  • Biying Shi,
  • Yuxuan Wang,
  • Yimeng Chen,
  • Xuanyi Wang,
  • Eui-Seok Lee and
  • Heng-Bo Jiang

23 February 2022

Guided tissue/bone regeneration (GTR/GBR) is commonly applied in dentistry to aid in the regeneration of bone/tissue at a defective location, where the assistive material eventually degrades to be substituted with newly produced tissue. Membranes sep...

  • Article
  • Open Access
32 Citations
7,112 Views
17 Pages

21 June 2022

Guided tissue/bone regeneration (GTR/GBR) is currently the main treatment for alveolar bone regeneration. The commonly used barrier membranes in GTR/GBR are collagen membranes from mammals such as porcine or cattle. Fish collagen is being explored as...

  • Review
  • Open Access
48 Citations
5,685 Views
11 Pages

Modifications of Polymeric Membranes Used in Guided Tissue and Bone Regeneration

  • Wojciech Florjanski,
  • Sylwia Orzeszek,
  • Anna Olchowy,
  • Natalia Grychowska,
  • Wlodzimierz Wieckiewicz,
  • Andrzej Malysa,
  • Joanna Smardz and
  • Mieszko Wieckiewicz

2 May 2019

Guided tissue/bone regeneration (GTR/GBR) is a widely used procedure in contemporary dentistry. To achieve the required results of tissue regeneration, soft tissues that reproduce quickly are separated from the slow-growing bone tissue by membranes....

  • Feature Paper
  • Article
  • Open Access
96 Citations
10,019 Views
24 Pages

A Novel Bilayer Polycaprolactone Membrane for Guided Bone Regeneration: Combining Electrospinning and Emulsion Templating

  • Betül Aldemir Dikici,
  • Serkan Dikici,
  • Gwendolen C. Reilly,
  • Sheila MacNeil and
  • Frederik Claeyssens

20 August 2019

Guided bone regeneration is a common dental implant treatment where a barrier membrane (BM) is used between epithelial tissue and bone or bone graft to prevent the invasion of the fast-proliferating epithelial cells into the defect site to be able to...

  • Review
  • Open Access
20 Citations
4,361 Views
10 Pages

10 December 2021

Periodontitis is a chronic infectious disease that destroys periodontal supportive tissues and eventually causes tooth loss. It is attributed to microbial and immune factors. The goal of periodontal therapy is to achieve complete alveolar bone regene...

  • Article
  • Open Access
8 Citations
3,006 Views
15 Pages

Osteoblasts and Fibroblasts Interaction with a Porcine Acellular Dermal Matrix Membrane

  • Pietro Felice,
  • Emira D’Amico,
  • Tania Vanessa Pierfelice,
  • Morena Petrini,
  • Carlo Barausse,
  • Maryia Karaban,
  • Antonio Barone and
  • Giovanna Iezzi

11 February 2023

The use of collagen membranes has remained the gold standard in GTR/GBR. In this study, the features and the biological activities of an acellular porcine dermis collagen matrix membrane applicable during dental surgery were investigated, and also by...

  • Article
  • Open Access
23 Citations
4,747 Views
17 Pages

Biocompatibility and Immune Response of a Newly Developed Volume-Stable Magnesium-Based Barrier Membrane in Combination with a PVD Coating for Guided Bone Regeneration (GBR)

  • Larissa Steigmann,
  • Ole Jung,
  • Wolfgang Kieferle,
  • Sanja Stojanovic,
  • Annica Proehl,
  • Oliver Görke,
  • Steffen Emmert,
  • Stevo Najman,
  • Mike Barbeck and
  • Daniel Rothamel

To date, there are no bioresorbable alternatives to non-resorbable and volume-stable membranes in the field of dentistry for guided bone or tissue regeneration (GBR/GTR). Even magnesium (Mg) has been shown to constitute a favorable biomaterial for th...

  • Article
  • Open Access
14 Citations
3,734 Views
11 Pages

20 October 2021

Biodegradable membranes are used in regenerative dentistry for guided tissue regeneration (GTR) and guided bone regeneration (GBR). In this study, patterned poly(lactic-co-glycolic acid) (PLGA) membranes with groove, pillar, and hole structures were...

  • Review
  • Open Access
42 Citations
7,457 Views
21 Pages

3D Printed and Bioprinted Membranes and Scaffolds for the Periodontal Tissue Regeneration: A Narrative Review

  • Irina-Georgeta Sufaru,
  • Georgiana Macovei,
  • Simona Stoleriu,
  • Maria-Alexandra Martu,
  • Ionut Luchian,
  • Diana-Cristala Kappenberg-Nitescu and
  • Sorina Mihaela Solomon

19 September 2022

Numerous technologies and materials were developed with the aim of repairing and reconstructing the tissue loss in patients with periodontitis. Periodontal guided bone regeneration (GBR) and guided tissue regeneration (GTR) involves the use of a memb...

  • Case Report
  • Open Access
6 Citations
4,953 Views
14 Pages

6 November 2022

The world of dentistry knows the benefits and results of guided bone regeneration. One of the most successful techniques introduced a decade ago utilizes, as a barrier membrane, a sheet made of collagenated xenograft called bone lamina. Indications a...

  • Review
  • Open Access
12 Citations
7,608 Views
20 Pages

Biomaterials for Guided Tissue Regeneration and Guided Bone Regeneration: A Review

  • Nathália Dantas Duarte,
  • Paula Buzo Frigério,
  • Gloria Estefania Amaya Chica,
  • Roberta Okamoto,
  • Rogério Leone Buchaim,
  • Daniela Vieira Buchaim,
  • Michel Reis Messora and
  • João Paulo Mardegan Issa

21 April 2025

This review aims to provide an overview of the types of membranes, bone substitutes, and mucosal substitutes used for GTR and GBR and briefly explores recent innovations for tissue regeneration and their future perspectives. Since this is a narrative...

  • Review
  • Open Access
9 Citations
4,067 Views
14 Pages

26 July 2022

A good barrier membrane is one of the important factors for effective guided bone/tissue regeneration (GBR/GTR) in the case of periodontal bone defects. Several methods are being discussed to overcome and improve the shortcomings of commercially avai...

  • Review
  • Open Access
38 Citations
8,242 Views
19 Pages

Past, Present, and Future of Regeneration Therapy in Oral and Periodontal Tissue: A Review

  • Hwa-Sun Lee,
  • Soo-Hwan Byun,
  • Seoung-Won Cho and
  • Byoung-Eun Yang

13 March 2019

Chronic periodontitis is the most common disease which induces oral tissue destruction. The goal of periodontal treatment is to reduce inflammation and regenerate the defects. As the structure of periodontium is composed of four types of different ti...

  • Article
  • Open Access
34 Citations
4,932 Views
12 Pages

27 October 2019

Poly(ε-caprolactone) (PCL) membranes have been widely used in guided tissue regeneration (GTR) and guided bone regeneration (GBR). In addition, hydroxyapatite is the major inorganic component and an essential composition of hard bone and teet...

  • Article
  • Open Access
41 Citations
5,486 Views
14 Pages

Production and Characterization of Porous Polymeric Membranes of PLA/PCL Blends with the Addition of Hydroxyapatite

  • Nayara Koba de Moura,
  • Idália A. W. B. Siqueira,
  • João Paulo de Barros Machado,
  • Hueliton Wilian Kido,
  • Ingrid Regina Avanzi,
  • Ana Claudia Muniz Rennó,
  • Eliandra de Sousa Trichês and
  • Fabio Roberto Passador

Polymer membranes have been widely used in guided tissue regeneration (GTR) and guided bone regeneration (GBR). The literature recognizes that poly (lactic acid) (PLA)/poly (ε-caprolactone) (PCL) blends have better physicochemical properties...

  • Article
  • Open Access
9 Citations
3,986 Views
14 Pages

Lithographically-Fabricated HA-Incorporated PCL Nanopatterned Patch for Tissue Engineering

  • Kyoung-Je Jang,
  • Sujin Kim,
  • Sangbae Park,
  • Woochan Kim,
  • Yonghyun Gwon,
  • Sunho Park,
  • Ki-Taek Lim,
  • Hoon Seonwoo and
  • Jangho Kim

1 April 2020

Inspired by the aligned extracellular matrix and bioceramics in human bone tissue, we investigated the relative contributions of nanotopography and equine bone powders (EBPs) with human dental pulp stem cells (DPSCs) to the osteogenesis. Both nanotop...

  • Review
  • Open Access
30 Citations
10,334 Views
20 Pages

Finding the Perfect Membrane: Current Knowledge on Barrier Membranes in Regenerative Procedures: A Descriptive Review

  • Sorina-Mihaela Solomon,
  • Irina-Georgeta Sufaru,
  • Silvia Teslaru,
  • Cristina Mihaela Ghiciuc and
  • Celina Silvia Stafie

20 January 2022

Guided tissue regeneration (GTR) and guided bone regeneration (GBR) became common procedures in the corrective phase of periodontal treatment. In order to obtain good quality tissue neo-formation, most techniques require the use of a membrane that wi...

  • Review
  • Open Access
7 Citations
4,695 Views
15 Pages

Advances in Synthetic Polymer Membranes for Guided Bone Regeneration in Dental Implants: A Scoping Review

  • Belén Lima-Sánchez,
  • María Baus-Domínguez,
  • María-Angeles Serrera-Figallo and
  • Daniel Torres-Lagares

Background: Different approaches are proposed for bone volume gain in the case of atrophic alveolar ridges, with guided bone regeneration (GBR) and guided tissue regeneration (GTR) being the most used techniques. These techniques require the placemen...

  • Article
  • Open Access
58 Citations
7,374 Views
11 Pages

Comparing Properties of Variable Pore-Sized 3D-Printed PLA Membrane with Conventional PLA Membrane for Guided Bone/Tissue Regeneration

  • Hao Yang Zhang,
  • Heng Bo Jiang,
  • Jeong-Hyun Ryu,
  • Hyojin Kang,
  • Kwang-Mahn Kim and
  • Jae-Sung Kwon

27 May 2019

The aim of this study was to fabricate bioresorbable polylactide (PLA) membranes by 3D printing and compare their properties to those of the membranes fabricated by the conventional method and compare the effect of different pore sizes on the propert...