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Article

24 Citations

12,124 Views

4 Pages

Preliminary Molecular Dynamic Simulations of the Estrogen Receptor Alpha Ligand Binding Domain from Antagonist to Apo

T. Dwight McGee,
Jesse Edwards and
Adrian E. Roitberg

Int. J. Environ. Res. Public Health2008, 5(2), 111-114;https://doi.org/10.3390/ijerph5020111

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30 June 2008

Estrogen receptors (ER) are known as nuclear receptors. They exist in the cytoplasm of human cells and serves as a DNA binding transcription factor that regulates gene expression. However the estrogen receptor also has additional functions independen...

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17 Pages

Molecular Association Assay Systems for Imaging Protein–Protein Interactions in Mammalian Cells

Sung-Bae Kim,
Tadaomi Furuta,
Suresh Thangudu,
Arutselvan Natarajan and
Ramasamy Paulmurugan

Biosensors2025, 15(5), 299;https://doi.org/10.3390/bios15050299

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8 May 2025

Molecular imaging probes play a pivotal role in assaying molecular events in various physiological systems. In this study, we demonstrate a new genre of bioluminescent probes for imaging protein–protein interactions (PPIs) in mammalian cells, n...

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