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Article

2,403 Views

12 Pages

Stress-Induced Changes in Nucleocytoplasmic Localization of Crucial Factors in Gene Expression Regulation

Ali Khamit,
Payal Chakraborty,
Szabolcs Zahorán,
Zoltán Villányi,
Hajnalka Orvos and
Edit Hermesz

Int. J. Mol. Sci.2024, 25(7), 3895;https://doi.org/10.3390/ijms25073895

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31 March 2024

This study investigates the toxic effect of harmful materials, unfiltered by the placenta, on neonatal umbilical cord (UC) vessels, focusing on stress-induced adaptations in transcriptional and translational processes. It aims to analyze changes in p...

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Article

5 Citations

3,757 Views

34 Pages

Disruption of the Mammalian Ccr4–Not Complex Contributes to Transcription-Mediated Genome Instability

Nafiseh Chalabi Hagkarim,
Morteza Chalabi Hajkarim,
Toru Suzuki,
Toshinobu Fujiwara,
G. Sebastiaan Winkler,
Grant S. Stewart and
Roger J. Grand

Cells2023, 12(14), 1868;https://doi.org/10.3390/cells12141868

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17 July 2023

The mammalian Ccr4–Not complex, carbon catabolite repression 4 (Ccr4)-negative on TATA-less (Not), is a large, highly conserved, multifunctional assembly of proteins that acts at different cellular levels to regulate gene expression. It is invo...

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