154 Results Found

Boron cluster-conjugated antisense oligonucleotides (B-ASOs) have already been developed as therapeutic agents with “two faces”, namely as potential antisense inhibitors of gene expression and as boron carriers for boron neutron capture t...

New boron carriers with high boron content and targeted cancer-cell delivery are considered the first choice for boron neutron capture therapy (BNCT) for cancer treatment. Previously, we have shown that composites of antisense oligonucleotide and bor...

Oligonucleotide tools, as modulators of alternative splicing, have been extensively studied, giving a rise to new therapeutic approaches. In this article, we report detailed research on the optimization of bifunctional antisense oligonucleotides (BAS...

Epidermal growth factor receptor (EGFR) is one of the most promising molecular targets for anticancer therapy. We used boron clusters as a platform for generation of new materials. For this, functional DNA constructs conjugated with boron clusters (B...

Little is known about ocular tics in Pediatric Autoimmune Neuropsychiatric Disorders associated with Streptococcal infections (PANDAS). In this retrospective study, we examined the clinical records of children with motor tics referred to the Ophthalm...

Barium sulfate (BaSO₄) is a material with high reflectance for preparing bifunctional sheets used in dry reagent chemical tests. In this study, bifunctional BaSO₄ sheets with scattering power and high reflectance were prepared with BaSO₄ microspheres...

The monoclinic rare-earth metal(III) bromide oxoarsenates(III) RE₅Br₃[AsO₃]₄ of the A-type (RE = La and Ce) crystallize in the space group C2/c with the lattice parameters a = 1834.67(9) pm, b = 553.41(3) pm, c = 1732.16(9) pm and β = 107.380(3)...

Antisense oligonucleotides conjugated with boron clusters (B-ASOs) have been described as potential gene expression inhibitors and carriers of boron for boron neutron capture therapy (BNCT), providing a dual-action therapeutic platform. In this study...

Geopolymers are a new environmentally friendly cementitious material, and the application of geopolymers can reduce the carbon dioxide emissions caused by the development of the cement industry. Purpose: This study investigates the radiation shieldin...

Radiative cooling is a new large-scale cooling technology with the promise of lowering costs and decreasing global warning. Currently, daytime radiative cooling is achieved via the application of reflective metal layers and complicated multilayer str...

This study of the BaSO₄-Bi phosphor has revealed that the accumulated energy after external optical excitation exhibits specific characteristics. During irradiation with photon energy exceeding the bandgap, in addition to the intrinsic ultraviolet em...

Ultrafine powder coatings are one of the development directions in the powder coating industry, as they can achieve thin coatings with good leveling and high surface smoothness comparable to liquid coatings. Compared to regular coatings, they experie...

In this research, polymer composite sheets were developed by blending poly (vinylidene fluoride-co-hexafluoropropylene) or P(VDF-HFP) with varying concentrations of barium sulfate (BaSO₄) for X-ray shielding applications. The photon counting techniqu...

The disposal and the reuse of industrial wastes have become increasingly difficult due to the elution of hazardous anions, such as F⁻, [B(OH)₄]⁻, AsO₄³⁻, and CrO₄²⁻. Effective methods for removing hazardous ions and reusing so...

This work experimentally determined the X-ray shielding and morphological, density, and tensile properties of sulfur-vulcanized natural rubber latex (SVNRL) nanocomposites containing varying content of nano-Bi₂O₃ or nano-BaSO₄ from 0 to 200 phr in 10...

The growth behavior and kinetics of the barite (001) surface in supersaturated BaSO₄ solutions (supersaturation index (SI) = 1.1–4.1) at 30 °C were investigated using in situ atomic force microscopy (AFM). At the lowest supersaturation, the growth be...

In this work the influence of carbon nano-dots (CNDs) on absorption of ultra violet (UV) spectra in hybrid PVA based composites was studied. The FTIR results reveal the complex formation between PVA and CNDs. The shifting was observed in XRD spectrum...

The PEO-based polymer nanocomposites were prepared by solution cast method. Green approaches were used for synthesis of carbon nanodots (CNDs) and silver nanoparticles (Ag NPs). It was found that the crystallite size of spherulites of PEO was greatly...

The Australian built environment is pivotal to achieving national net-zero targets, yet progress remains slow due to fragmented policy frameworks, low retrofit adoption, and uneven integration of emerging technologies. Despite these challenges, littl...

Avian pathogenic Escherichia coli (APEC), such as O1, O2 and O78, are important serogroups relating to chicken health, being responsible for colibacillosis. In this study, we isolated and characterized bacteriophages (phages) from hen feces and...

This study develops and validates an integrated hydrometallurgical process to recover battery-grade lithium hydroxide monohydrate from spent aluminosilicate sagger crucibles. Lithium was first leached as Li₂SO₄ from the crucibles using sulfuric acid;...

The emergence of bacterial resistance to traditional small-molecule antibiotics is fueling the search for innovative strategies to treat infections. Inhibiting the expression of essential bacterial genes using antisense oligonucleotides (ASOs), parti...

Na_1.5Mn^II₃Mn^III_0.5(AsO₄)₃ and Na_1.5Mn^II₃Fe^III_0.5(AsO₄)₃ compounds were synthesized via a high-temperature solid-state combustion reaction. The obtained samples were submitted to structural, morphological, and electrical characterizations. X-ray diffr...

Single-crystals of lead(II) oxoarsenates(V) were grown from the melt (Pb₂As₂O₇), from solution (Pb(H₂AsO₄)₂ and Pb₅(AsO₄)₃OH), and under hydrothermal conditions (NaPb₄(AsO₄)₃). Crystal structure refinements from single-crystal X-ray diffraction data...

The luminal B molecular subtype of breast cancers (BC) accounts for more than a third of BCs and is associated with aggressive clinical behavior and poor prognosis. The use of endocrine therapy in BC treatment has significantly contributed to the dec...

Y₅F₃[AsO₃]₄ crystallizes needle-shaped in the tetragonal space group P4/ncc with the lattice parameters a = 1143.80(8) pm, c = 1078.41(7) pm and c/a = 0.9428 for Z = 4. The yttrium-fluoride substructure linked via secondary contacts forms a three-dim...

The poly(o-anisidine)/BaSO₄ nanocomposites were prepared by oxidative polymerization of o-anisidine monomer with BaSO₄ filler for the potential antibacterial properties of the composite materials. To achieve the optimal and tunable properties of the...

In this study, BaCe_0.9Er_0.1O_3−α was synthesized by a microemulsion method. Then, a BaCe_0.9Er_0.1O_3−α–K₂SO₄–BaSO₄ composite electrolyte was obtained by compounding it with a K₂SO₄–Li₂SO₄ solid solution. BaCe_0.9...

The issues of trace element emissions during coal combustion has been a concern in recent years due to their environmental pollutant. To study the trace element transformation, the thermodynamic calculation (FactSage 7.2) was used. Five kinds of pure...

Boron cluster-modified therapeutic nucleic acids with improved properties are of interest in gene therapy and in cancer boron neutron capture therapy (BNCT). High metallacarborane-loaded antisense oligonucleotides (ASOs) targeting epidermal growth fa...

Gnomoniopsis smithogilvyi (Gs) is a relevant pathogen of chestnut since it provokes significant losses worldwide. The aim of this study was to screen the effect of a new biocontrol agent (BCA) against Gs isolated from chestnut (CIMO-BCA1) on the moul...

Poly(methyl methacrylate) (PMMA) bone cements have been widely used in clinical practices. In order to enhance PMMA’s imaging performance to facilitate surgical procedures, a supplementation of radiopaque agent is needed. However, PMMA bone cem...

The B-cell lymphoma 2 (Bcl-2) family, comprised of pro- and anti-apoptotic proteins, regulates the delicate balance between programmed cell death and cell survival. The Bcl-2 family is essential in the maintenance of tissue homeostasis, but also a ke...

Tooeleite [Fe₆(AsO₃)₄(SO₄)(OH)₄·4H₂O] was synthesized and characterized to investigate its possible immobilization for arsenic in acidic and alkali environments by a long-term dissolution of 330 d. The synthetic tooeleite was platy crystallite...

Common synthetic dyes, e.g., Weak Acid Pink Red B (APRB, C.I. 18073), Mordant Blue 9 (MB, C.I.14855) and Acid Brilliant Blue 6B (ABB6B, C.I. 42660), can be removed from water by in situ hybridization with CaCO₃, BaSO₄ and Ca₃(PO₄)₂ and the resulting...

Nanoclay has proven to be an active anti-corrosive additive due to the self-repairing effect from nanoclay swelling and expansion, except for its passive barrier effect due to the high aspect ratio. But it is still uncertain how these effects of nano...

Sirt1 is a NAD⁺-dependent protein-modifying enzyme involved in regulating gene expression, DNA damage repair, metabolism and survival, as well as acts as an important subcellular target of resveratrol. The complex mechanisms underlying Sirt1 signalin...

Glioblastoma (GBM) is the most aggressive primary cancer with poor survival. In the absence of an effective treatment and a high probability of recurrence, new therapeutic approaches are urgently needed. This study focused on targeting microRNA-10b (...

Poly(ε-caprolactone) (PCL) was mixed with submicron particles of barium sulfate to obtain biodegradable radiopaque composites. X-ray images comparing with aluminum samples show that 15 wt.% barium sulfate (BaSO₄) is sufficient to present radiopacity....

A passive cooling method with great potential to lower space-cooling costs, counteract the urban heat island effect, and slow down worldwide warming is radiant cooling. The solutions available frequently require complex layered structures, costly pro...

This study aims to investigate the influencing factors and mechanisms of barium sulfate (BaSO₄) scaling under low-permeability reservoir conditions, providing a scientific basis for water quality selection during water injection. The effects of key s...

Sustainable hydrocarbons are one of the main methods of decreasing the use of fossil fuels and derivatives, contributing to the mitigation of environmental impacts and greenhouse gas emissions. Circular economic concepts focus on reusing waste by con...

The results of studies on the corrosion protectiveness and thermal conductivity of reduced graphene oxide–BaSO₄ epoxy composites are reported here. A commercial epoxy resin and reduced graphene oxide (rGO) were blended with a hardening reagent...

Single crystals of the novel boroarsenate (K,Na)₂[As₂B₁₂O₂₄][B₃O₃(OH)₃] (I) were obtained using the borax flux method. The crystal structure of I was found to be triclinic, P-1, a = 8.414(5), b = 10.173(6), c = 15.90(1) Å, α = 79.56(1), &...

Membrane distillation (MD) is fast evolving as a desalination technology for high-salinity waters where scaling remains a major challenge. This paper reports the scaling reduction in carbon nanotube-immobilized membranes (CNIMs) and by the use of the...

Potential evapotranspiration (PET) indicates if a cultivation area is suitable for planting. Currently, site-specific PET models that are based on large geographic regions are vulnerable to inaccurate predictions as a result of climate change and sud...

This study sought to design and characterize the Fe, SiC, Cu, and C metal matrix composite (MMC) with optimum SiC content to obtain sufficiently good wear resistance performance. For this purpose, Fe, Cu, graphite, and BaSO₄ (Fe-11Cu-6.5G-6BaSO₄) wit...

Objective: Natural polyphenol Calebin A has been recently discovered as a novel derivate from turmeric with anti-cancer potential. Pro-inflammatory cytokine TNF-β (lymphotoxin α) is a stimulant for cancer cell malignity via activation of N...

Oral delivery is considered as the most preferred and yet most challenging mode of drug administration; especially a fragile and sensitive peptide like insulin that shows extremely low bioavailability through the gastro-intestinal (GIT) route. To add...

Rare-earth-doped nanoparticles have been investigated for their use in disease diagnosis, drug delivery, tumor therapy and bioimaging. In this context, we selected BaSO₄:Eu phosphor nanoparticles, commercially available from Merck (Darmstadt, Germany...