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  • Article
  • Open Access
13 Citations
4,368 Views
14 Pages

Cepharanthine Alleviates DSS-Induced Ulcerative Colitis via Regulating Aconitate Decarboxylase 1 Expression and Macrophage Infiltration

  • Min-Na Zhang,
  • Rui Xie,
  • Hong-Gang Wang,
  • Xin Wen,
  • Jing-Yi Wang,
  • Le He,
  • Meng-Hui Zhang and
  • Xiao-Zhong Yang

20 January 2023

Cepharanthine (CEP), a bisbenzylisoquinoline alkaloid from tubers of Stephania, protects against some inflammatory diseases. Aconitate decarboxylase 1 (ACOD1) is also known as immune-responsive gene 1 (IRG1), which plays an important immunometabolism...

  • Article
  • Open Access
23 Citations
4,749 Views
13 Pages

Aconitate Decarboxylase 1 Deficiency Exacerbates Mouse Colitis Induced by Dextran Sodium Sulfate

  • Ho Won Kim,
  • A-Reum Yu,
  • Ji Won Lee,
  • Hoe Sun Yoon,
  • Byung Soo Lee,
  • Hwan-Woo Park,
  • Sung Ki Lee,
  • Young Ik Lee,
  • Jake Whang and
  • Jong-Seok Kim

Ulcerative colitis is a complex inflammatory bowel disorder disease that can induce rectal and colonic dysfunction. Although the prevalence of IBD in Western countries is almost 0.5% of the general population, genetic causes are still not fully under...

  • Article
  • Open Access
1,396 Views
12 Pages

Itaconate: A Nexus Metabolite Fueling Leishmania Survival Through Lipid Metabolism Modulation

  • Ayyoub Kihel,
  • Hajar El Filaly,
  • Dounia Darif,
  • Aicha Assouab,
  • Myriam Riyad,
  • Imane Nait Irahal and
  • Khadija Akarid

Leishmaniasis, caused by the Leishmania parasite, is a neglected public health issue. Leishmania mainly infects macrophages, where metabolic reprogramming shapes their plasticity (M1/M2), affecting the host’s resistance or susceptibility to inf...

  • Article
  • Open Access
12 Citations
3,447 Views
15 Pages

Lag Phase in the Anaerobic Co-Digestion of Sargassum spp. and Organic Domestic Waste

  • Héctor Alfredo López-Aguilar,
  • Bryan Morales-Durán,
  • David Quiroz-Cardoza and
  • Antonino Pérez-Hernández

18 July 2023

The mass arrival of pelagic sargassum is an international issue that is currently taking its toll on the economic activity of affected regions by causing a significant reduction in investment and tourism. The purpose of this work was to evaluate the...

  • Article
  • Open Access
1 Citations
1,701 Views
19 Pages

Optimizing Biomethane Production from Industrial Pig Slurry and Wine Vinasse: A Mathematical Approach

  • Belén Cañadas,
  • Juana Fernández-Rodríguez,
  • Rosario Solera and
  • Montserrat Pérez

Pig slurry (PS) and wine vinasse (WV) pose environmental risks if not properly managed. Their composition makes them suitable for anaerobic co-digestion (AcoD), enhancing biomethane production and improving organic matter degradation efficiency. This...

  • Proceeding Paper
  • Open Access
1 Citations
1,963 Views
6 Pages

Deuteration of Alkenes with NaBD4/AcOD in Pre-Sence of Pd on Carbon

  • Fatima AlJunaibi,
  • Hanan Aldhanhani,
  • Halima Alawani,
  • Amnah Al Hmoudi,
  • Abdullah Al-Hemyari and
  • Thies Thiemann

14 November 2019

Activated alkenes such as cinnamates and chalcones can easily be converted to 2,3-dideuterio-arylpropionates and dideuteriochalcones, respectively, by the action of NaBD4, AcOD in the presence of Pd on carbon. Toluene or benzene was used as solvent....

  • Article
  • Open Access
5 Citations
2,936 Views
31 Pages

Unraveling the Protective Role of Oleocanthal and Its Oxidation Product, Oleocanthalic Acid, against Neuroinflammation

  • Maria Cristina Barbalace,
  • Michela Freschi,
  • Irene Rinaldi,
  • Lorenzo Zallocco,
  • Marco Malaguti,
  • Clementina Manera,
  • Gabriella Ortore,
  • Mariachiara Zuccarini,
  • Maurizio Ronci and
  • Cristina Angeloni
  • + 5 authors

3 September 2024

Neuroinflammation is a critical aspect of various neurodegenerative diseases, such as Alzheimer’s and Parkinson’s diseases. This study investigates the anti-neuroinflammatory properties of oleocanthal and its oxidation product, oleocantha...

  • Article
  • Open Access
1,618 Views
18 Pages

Effect of Organic Nitrogen Supply on the Kinetics and Quality of Anaerobic Digestion of Less Nitrogenous Substrates: Case of Anaerobic Co-Digestion (AcoD) of Cassava Effluent and Chicken Droppings as a Nitrogen Source

  • Haro Kayaba,
  • Nourou Abdel Anziph Sergel Khalid,
  • Sandwidi Sayouba,
  • Compaore Abdoulaye,
  • Palm Sie Auguste,
  • Sessouma Oumou,
  • Ouedraogo Ibrahim Kourita,
  • Sinon Souleymane,
  • Tubreoumya Guy Christian and
  • Sanogo Oumar
  • + 2 authors

30 December 2024

This study aims to explore anaerobic co-digestion (AcoD) of cassava (EUM) and poultry (FP) effluents using one inoculum/substrate ratio (30%) and three EUM vs. FP substrate composition ratios (25:75, 50:50, and 75:25). The AcoD process was therefore...

  • Article
  • Open Access
4 Citations
2,235 Views
15 Pages

14 October 2024

This study investigated the impact of a transglycosylated product (ACOD) catalyzed by Leuconostoc mesenteroides MKSR dextransucrase using sucrose as a glucosyl donor and both maltose and Artemisia capillaris as acceptors on gut microbiota through fec...

  • Article
  • Open Access
7 Citations
2,803 Views
16 Pages

21 April 2022

Anaerobic co-digestion (AcoD) has been a widely accepted method to treat food waste (FW) and sewage sludge (SS). However, there is a knowledge gap regarding the key speciation transformation of nitrogen and sulfur in AcoD. Here, we explored the chang...

  • Article
  • Open Access
13 Citations
4,576 Views
14 Pages

Anaerobic Co-Digestion of Sugarcane Leaves, Cow Dung and Food Waste: Focus on Methane Yield and Synergistic Effects

  • Sunqiang Xu,
  • Guican Bi,
  • Xiangmeng Liu,
  • Qiang Yu,
  • Dong Li,
  • Haoran Yuan,
  • Yong Chen and
  • Jun Xie

Anaerobic co-digestion (AcoD) of food waste (FW) and lignocellulose waste is a promising technology for methane production. This work investigated the methane generation from AcoD of FW, sugarcane leaves (SLs), and cow dung (CD) under mesophilic cond...

  • Article
  • Open Access
5 Citations
3,288 Views
17 Pages

The Effects of Nanoparticles- Zerovalent Iron on Sustainable Biomethane Production through Co-Digestion of Olive Mill Wastewater and Chicken Manure

  • Khalideh Al Bkoor Alrawashdeh,
  • Kamel K. Al-Zboon,
  • Jalal A. Al-Tabbal,
  • La’aly A. AL-Samrraie,
  • Abeer Al Bsoul,
  • Rebhi A. Damseh,
  • Ayat Khasawneh,
  • Yasser Dessouky,
  • Kareem Tonbol and
  • Elen E. Youssef
  • + 1 author

The impacts of nanoparticles-zerovalent iron (NP-ZVI) on anaerobic co-digestion (AcoD) were assessed. The production of biogas and methane (CH4), as well as the removal efficiency of volatile solids (VS) and contaminants were investigated in the AcoD...

  • Article
  • Open Access
2 Citations
1,187 Views
27 Pages

Anaerobic Co-Digestion of Food Waste in Ghana: Biological Methane Potential and Process Stabilisation Challenges in a Rural Setting

  • Raquel Arnal-Sierra,
  • Simone Colantoni,
  • Albert Awopone,
  • Isaac Boateng,
  • Kingsley Agyapong,
  • Frederick Kwaku Sarfo,
  • Daniele Molognoni and
  • Eduard Borràs

22 August 2025

In rural Ghana, limited access to affordable, clean cooking fuels drives the need for decentralised waste-to-energy solutions. Anaerobic co-digestion (AcoD) offers a viable route for transforming organic residues into renewable energy, with the added...

  • Review
  • Open Access
1 Citations
1,774 Views
25 Pages

The Use of Crude Glycerol as a Co-Substrate for Anaerobic Digestion

  • Wirginia Tomczak,
  • Sławomir Żak,
  • Anna Kujawska and
  • Maciej Szwast

8 September 2025

One of the most interesting applications of crude glycerol (CG) is its use for biogas production via the anaerobic co-digestion (AcoD) process. The main aim of the current study was to provide a comprehensive review on the performance of the AcoD of...

  • Article
  • Open Access
6 Citations
4,373 Views
14 Pages

Anaerobic Co-Digestion of Cattle Manure and Brewer’s Residual Yeast: Process Stability and Methane and Hydrogen Sulfide Production

  • Luana Alves Akamine,
  • Roberta Passini,
  • João Antônio Silva Sousa,
  • Aline Fernandes and
  • Maria Joselma de Moraes

Anaerobic co-digestion (AcoD) of animal waste and agro-industrial by-products has been widely studied and employed to increase biogas production potential and enhance process stability. This study evaluated the AcoD of cattle manure (CM) and brewer’s...

  • Article
  • Open Access
6 Citations
2,774 Views
16 Pages

The local waste co-digestion is an interesting option to tackle in reduced and isolated areas like the islands. The islands have limited territory and scarce fuel production. Moreover, organic waste can create serious environmental problems in soil,...

  • Article
  • Open Access
4 Citations
4,432 Views
18 Pages

Co-Digestion-Based Circular Bio-Economy to Improve Biomethane Generation and Production of Nutrient-Enriched Digestate in Bangladesh

  • Chayan Kumer Saha,
  • Mst. Lucky Khatun,
  • Jannatoon Nime,
  • Kawnish Kirtania and
  • Md. Monjurul Alam

21 December 2023

Anaerobic co-digestion (ACoD) of cow dung (CD) and maize cob (MC) may be envisaged as the best way to enhance biomethane formation and production of nutrient-enriched fertilizer for the implementation of a circular bio-economic system. The study aime...

  • Article
  • Open Access
21 Citations
5,964 Views
21 Pages

19 April 2022

Earth observation satellite (EOS) systems often encounter emergency observation tasks oriented to sudden disasters (e.g., earthquake, tsunami, and mud-rock flow). However, EOS systems may not be able to provide feasible coverage time windows for emer...

  • Review
  • Open Access
899 Views
24 Pages

25 November 2025

Artificial intelligence (AI) has emerged as an innovative approach to the computer modeling and optimization of anaerobic digestion (AD) and anaerobic co-digestion (AcoD) processes. AI-based algorithms are ideally suited to capture the complex nonlin...

  • Article
  • Open Access
571 Views
14 Pages

Adding Digestive Enzymes to Anaerobic Co-Digestion of Cattle Manure and Industrial Corn Grain Waste

  • Laís Medeiros Cintra,
  • Roberta Passini,
  • Luana Alves Akamine,
  • Kedinna Dias de Sousa,
  • Frank Freire Capuchinho,
  • Sérgio Botelho de Oliveira and
  • Silvia Robles Reis Duarte

Brazil is one of the world’s largest producers of grains and cattle, activities that generate a large amount of organic waste, which has high potential for biogas and methane production. Cattle manure (CM) and industrial waste from corn process...

  • Review
  • Open Access
41 Citations
8,363 Views
19 Pages

Impacts of Anaerobic Co-Digestion on Different Influencing Parameters: A Critical Review

  • Mohammed Kelif Ibro,
  • Venkata Ramayya Ancha and
  • Dejene Beyene Lemma

31 July 2022

Lignocellulosic feedstocks are year-round, available bio-residues that are the right candidates for counteracting the energy crises and global warming facing the world today. However, lignin leads to a slow hydrolysis rate and is a major bottleneck f...

  • Article
  • Open Access
4,272 Views
16 Pages

Anaerobic Co-Digestion of Brewers’ Spent Grain from Craft Beer and Cattle Manure for Biogas Production

  • Héctor Alfredo López-Aguilar,
  • Antonino Pérez-Hernández,
  • Humberto Alejandro Monreal-Romero,
  • Claudia López Meléndez,
  • María del Rosario Peralta-Pérez and
  • Francisco Javier Zavala-Díaz de la Serna

1 September 2025

The brewing industry generates significant organic waste, much of which remains underutilized despite its potential for energy recovery. This study assesses the feasibility of anaerobic co-digestion (AcoD) using brewers’ spent grain (BSG) from...

  • Article
  • Open Access
11 Citations
3,731 Views
22 Pages

13 January 2021

Usually, slaughterhouse wastewater has been considered as a single substrate whose anaerobic digestion can lead to inhibition problems and low biodegradability. However, the bovine slaughter process generates different wastewater streams with particu...

  • Article
  • Open Access
13 Citations
4,027 Views
12 Pages

The aim of this study was to evaluate the effect of the inoculum to substrate ratio (ISR) and the mixture ratio between organic fraction of municipal solid waste (OFMSW) and sewage sludge (SS) on the methane production potential achievable from anaer...

  • Article
  • Open Access
3 Citations
2,638 Views
13 Pages

Investigation on the Interactive Effects between Temperature and Chemical Composition of Organic Wastes on Anaerobic Co-Digestion Performance

  • Siqi Zhang,
  • Ying Wang,
  • Jinghui Song,
  • Chenjing Sheng,
  • Zezhou Shang,
  • Rui Wang,
  • Xiaojiao Wang,
  • Gaihe Yang,
  • Yongzhong Feng and
  • Guangxin Ren

20 September 2021

Synergistic effects among different chemical components under the anaerobic co-digestion (AcoD) process played an important role in improving its performance, which might be affected by the digesting temperature. The results showed that the actual me...

  • Article
  • Open Access
14 Citations
3,426 Views
16 Pages

Pretreatment and codigestion are proven to be effective strategies for the enhancement of the anaerobic digestion of lignocellulosic residues. The purpose of this study is to evaluate the effects of pretreatment and codigestion on methane production...

  • Article
  • Open Access
9 Citations
3,270 Views
12 Pages

The Effects of Using Pretreated Cotton Gin Trash on the Production of Biogas from Anaerobic Co-Digestion with Cow Manure and Sludge

  • Muhammad Usman Hanif,
  • Mohammed Zwawi,
  • Mohammed Algarni,
  • Ali Bahadar,
  • Hamid Iqbal,
  • Sergio C. Capareda,
  • Muhammad Adnan Hanif,
  • Adeel Waqas,
  • Nazia Hossain and
  • Asma Jamil
  • + 2 authors

11 January 2022

Anaerobic co-digestion (AcoD) has been practiced for decades to convert waste into value-added energy products, especially biogas. This study aimed to assess the potential of biogenic methane (CH4) production from the co-digestion of pretreated cotto...

  • Review
  • Open Access
13 Citations
3,994 Views
20 Pages

19 September 2024

Wheat straw (WS) is a promising substrate for biogas production by anaerobic digestion (AD) due to its high carbohydrate content. An estimated 0.603 million t yr−1 of WS are generated from wheat production systems in South Africa. This is equiv...

  • Article
  • Open Access
1,818 Views
17 Pages

Leveraging Potato Chip Industry Residues: Bioenergy Production and Greenhouse Gas Mitigation

  • Patrícia V. Almeida,
  • Luís M. Castro,
  • Anna Klepacz-Smółka,
  • Licínio M. Gando-Ferreira and
  • Margarida J. Quina

30 May 2025

Anaerobic digestion (AD) offers a sustainable solution by treating biodegradable waste while recovering bioenergy, enhancing the share of renewable energy. Thus, this study aims to investigate the AD for managing and valorizing residues from the pota...

  • Article
  • Open Access
504 Views
16 Pages

1 January 2026

Background: Tumor-associated neutrophils (TANs) exhibit remarkable functional plasticity within tumor microenvironment (TME), with N1-like subtypes promoting anti-tumor immunity and N2-like subtypes facilitating tumor progression. Despite their criti...

  • Article
  • Open Access
20 Citations
3,505 Views
19 Pages

The Use of Lignin as a Microbial Carrier in the Co-Digestion of Cheese and Wafer Waste

  • Agnieszka A. Pilarska,
  • Agnieszka Wolna-Maruwka,
  • Krzysztof Pilarski,
  • Damian Janczak,
  • Krzysztof Przybył and
  • Marzena Gawrysiak-Witulska

12 December 2019

The aim of the article was to present the effects of lignin grafted with polyvinylpyrrolidone (PVP) as a microbial carrier in anaerobic co-digestion (AcoD) of cheese (CE) and wafer waste (WF). Individual samples of waste cheese and wafers were also t...

  • Article
  • Open Access
3 Citations
3,990 Views
16 Pages

20 August 2022

Slaughterhouse wastewater (SHWW) has a great potential to generate biomethane energy when subjected to anaerobic digestion (AD). Nonetheless, the process is susceptible and prone to failure because of slow hydrolysis and the production of inhibitory...

  • Article
  • Open Access
9 Citations
3,118 Views
41 Pages

18 June 2024

A wireless sensor network (WSN) is a wireless network composed of sensor nodes, widely used in military, industrial, and agricultural fields. In these practical application scenarios, due to the limited routing search ability of wireless sensor nodes...

  • Article
  • Open Access
2 Citations
2,409 Views
14 Pages

Study of the Effect of Temperature to Optimize the Anaerobic Digestion of Slaughterhouse Sludge by Co-Digestion with Slaughterhouse Wastewater

  • Maria Candel,
  • Laura Ballesteros,
  • Juana Fernandez-Rodriguez,
  • Montserrat Perez and
  • Rosario Solera

The anaerobic co-digestion (ACoD) of sludge (S) and slaughterhouse wastewater (SW) can improve biomethane production and removal efficiency in terms of organic matter. The aim of this study was to determine the impact of temperature on co-digestion,...

  • Article
  • Open Access
56 Citations
8,769 Views
15 Pages

18 February 2021

Itaconate is a small molecule metabolite that is endogenously produced by cis-aconitate decarboxylase-1 (ACOD1) in mammalian cells and influences numerous cellular processes. The metabolic consequences of itaconate in cells are diverse and contribute...

  • Feature Paper
  • Article
  • Open Access
8 Citations
3,823 Views
16 Pages

Optimization and Analysis of Liquid Anaerobic Co-Digestion of Agro-Industrial Wastes via Mixture Design

  • Roberto Eloy Hernández Regalado,
  • Tobias Weide,
  • Daniel Baumkötter,
  • Lukas Wettwer,
  • Jurek Häner,
  • Elmar Brügging and
  • Jens Tränckner

17 May 2021

Anaerobic co-digestion (AcoD) is a widely employed technique to produce biogas from simultaneous digestion of various biomasses. However, the selection of the optimal proportions of the substrates in the mixtures presents a challenge. This research u...

  • Article
  • Open Access
4 Citations
2,412 Views
12 Pages

Effect of Antibiotics and Thermophilic Pre-Treatment on Anaerobic Co-Digestion of Pig Manure and Corn Straw

  • Qinxue Wen,
  • Solomon Tsegay Asfaw,
  • Shuo Yang,
  • Zhiqiang Chen,
  • Salman Abdu Ahmed,
  • Yixin Li and
  • Henok Shiferaw

11 September 2023

The excessive use of antibiotics in the pig breeding industry leads to the accumulation of antibiotic residuals in the environment, which is attributed to the improper treatment of livestock excrements. Sulfamethoxazole (SMX) and Norfloxacin (NOR) ar...

  • Article
  • Open Access
5 Citations
3,299 Views
17 Pages

Gene Expression Profiling of Classically Activated Macrophages in Leishmania infantum Infection: Response to Metabolic Pre-Stimulus with Itaconic Acid

  • Génesis Palacios,
  • Elva Vega-García,
  • Basilio Valladares,
  • José Antonio Pérez,
  • Roberto Dorta-Guerra and
  • Emma Carmelo

Leishmania infection of phagocytic cells, such as macrophages, induces the differentiation of infected cells into different phenotypes according to their surrounding microenvironments. The classical activation of macrophages involves metabolic reprog...

  • Article
  • Open Access
3 Citations
3,057 Views
18 Pages

24 October 2023

RNA sequencing makes it possible to uncover genetic mechanisms that underlie certain performance traits. In order to gain a deeper insight into the genetic background and biological processes involved in endurance performance in horses, the changes i...

  • Article
  • Open Access
27 Citations
7,129 Views
22 Pages

Simulation and Optimization of Anaerobic Co-Digestion of Food Waste with Palm Oil Mill Effluent for Biogas Production

  • Jasmine Sie Ming Tiong,
  • Yi Jing Chan,
  • Jun Wei Lim,
  • Mardawani Mohamad,
  • Chii-Dong Ho,
  • Anisa Ur Rahmah,
  • Worapon Kiatkittipong,
  • Wipoo Sriseubsai and
  • Izumi Kumakiri

10 December 2021

Food waste (FW) utilized as substrate for anaerobic digestion (AD) to produce biogas is promising. Simultaneously, waste is handled and value-added products such as biogas and fertilizer are produced. Palm oil mill effluent (POME) is used as the co-s...

  • Article
  • Open Access
8 Citations
3,571 Views
17 Pages

Sewage scum (SS) is collected from sedimentation tanks in wastewater treatment plants (WWTPs). Despite its huge biogas potential, there is limited information on its potential as a co-substrate and microbial ecology, especially during anaerobic co-di...

  • Review
  • Open Access
49 Citations
14,792 Views
23 Pages

Anaerobic Digestion of Food Waste—A Short Review

  • Agnieszka A. Pilarska,
  • Tomasz Kulupa,
  • Adrianna Kubiak,
  • Agnieszka Wolna-Maruwka,
  • Krzysztof Pilarski and
  • Alicja Niewiadomska

1 August 2023

In recent years, growing environmental awareness, the need to reduce greenhouse gas emissions, and the energy crisis have led many countries to seek alternative energy sources. One of the most promising solutions is biogas production via anaerobic di...

  • Article
  • Open Access
2 Citations
2,556 Views
14 Pages

Mango Peel Nanofiltration Concentrates to Enhance Anaerobic Digestion of Slurry from Piglets Fed with Laminaria

  • Antónia Macedo,
  • Rita Fragoso,
  • Inês Silva,
  • Tânia Gomes,
  • Cátia F. Martins,
  • João Bengala Freire and
  • Elizabeth Duarte

The environmental impact of biowaste generated during animal production can be mitigated by applying a circular economy model: recycling, reinventing the life cycle of biowaste, and developing it for a new use. The aim of this study was to evaluate t...

  • Article
  • Open Access
17 Citations
5,508 Views
24 Pages

Altered Transcription Factor Binding and Gene Bivalency in Islets of Intrauterine Growth Retarded Rats

  • Yu-Chin Lien,
  • Paul Zhiping Wang,
  • Xueqing Maggie Lu and
  • Rebecca A. Simmons

9 June 2020

Intrauterine growth retardation (IUGR), which induces epigenetic modifications and permanent changes in gene expression, has been associated with the development of type 2 diabetes. Using a rat model of IUGR, we performed ChIP-Seq to identify and map...

  • Article
  • Open Access
3 Citations
2,052 Views
18 Pages

Comparative Transcriptome Analyses Provide New Insights into the Evolution of Divergent Thermal Resistance in Two Eel Gobies

  • Jing Liu,
  • Tianwei Liu,
  • Yantao Liu,
  • Yuzhen Wang,
  • Liqin Liu,
  • Li Gong,
  • Bingjian Liu and
  • Zhenming Lü

25 December 2023

Adaptation to thermal conditions in tidal mudflats always involves tolerating frequent fluctuations and often extreme environmental temperatures. Regulation of gene expression plays a fundamental role in the evolution of these thermal adaptations. To...

  • Article
  • Open Access
16 Citations
5,330 Views
18 Pages

20 October 2021

Anaerobic co-digestion technology (AcoD) can be used to process rice straw (RS) and cow manure (CoM) to produce energy and a digestate rich in nutrients, while the improper disposal of RS and CoM causes environmental problems. The overall effectivene...

  • Review
  • Open Access
9 Citations
3,850 Views
20 Pages

Population Disequilibrium as Promoter of Adaptive Explorations in Hepatitis C Virus

  • Carlos García-Crespo,
  • Isabel Gallego,
  • María Eugenia Soria,
  • Ana Isabel de Ávila,
  • Brenda Martínez-González,
  • Lucía Vázquez-Sirvent,
  • Rebeca Lobo-Vega,
  • Elena Moreno,
  • Jordi Gómez and
  • Celia Perales
  • + 4 authors

3 April 2021

Replication of RNA viruses is characterized by exploration of sequence space which facilitates their adaptation to changing environments. It is generally accepted that such exploration takes place mainly in response to positive selection, and that fu...

  • Article
  • Open Access
1 Citations
2,833 Views
20 Pages

16 October 2025

The global demand for processed foods has increased reliance on synthetic phenolic antioxidants (SPAs), including tert-butylhydroquinone (TBHQ), a widely used additive to prevent lipid oxidation and extend shelf life. TBHQ is considered safe at prese...

  • Article
  • Open Access
1,265 Views
16 Pages

Female Mice Lacking LSD1 in Myeloid Cells Are Resistant to Inflammatory Bone Loss

  • Kristina Astleford-Hopper,
  • Flavia Saavedra,
  • Peter Bittner-Eddy,
  • Clara Stein,
  • Jennifer Auger,
  • Rachel Clark,
  • Juan E. Abrahante Llorens,
  • Bryce A. Binstadt,
  • Vivek Thumbigere-Math and
  • Kim C. Mansky

19 July 2025

Osteoclasts, which are derived from myeloid precursors, are essential for physiologic bone remodeling but also mediate pathological bone loss in inflammatory diseases such as periodontitis and rheumatoid arthritis. Lysine-specific demethylase (LSD1/K...

  • Article
  • Open Access
1 Citations
2,348 Views
26 Pages

Transcriptome Profiling of Oncorhynchus mykiss Infected with Low or Highly Pathogenic Viral Hemorrhagic Septicemia Virus (VHSV)

  • Lorena Biasini,
  • Gianpiero Zamperin,
  • Francesco Pascoli,
  • Miriam Abbadi,
  • Alessandra Buratin,
  • Andrea Marsella,
  • Valentina Panzarin and
  • Anna Toffan

The rainbow trout (Oncorhynchus mykiss) is the most important produced species in freshwater within the European Union, usually reared in intensive farming systems. This species is highly susceptible to viral hemorrhagic septicemia (VHS), a severe sy...

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