Search Results (1,487)

Agricultural marketing increasingly integrates Agriculture 4.0 technologies—Blockchain, AI/ML, IoT, and recommendation systems—yet systematic evaluations of computational maturity and deployment readiness remain limited. This Systematic Literature Review (SLR) examined 99 peer-reviewed studies (2019–2025) from Scopus, Web of Science, and IEEE Xplore following PRISMA protocols to assess algorithmic performance, evaluation methods, and Technology Readiness Levels (TRLs) for agricultural marketing applications. Hybrid recommendation systems dominate current research (28.3%), achieving accuracies of 80–92%, while blockchain implementations (15.2%) show fast transaction times (<2 s) but limited real-world adoption. Machine learning models using Random Forest, Gradient Boosting, and CNNs reach 85–95% predictive accuracy, and IoT systems report >95% data transmission reliability. However, 77.8% of technologies remain at validation stages (TRL ≤ 5), and only 3% demonstrate operational deployment beyond one year. The findings reveal an “efficiency paradox”: strong technical performance (75–97/100) contrasts with weak economic validation (≤20% include cost–benefit analysis). Most studies overlook temporal, geographic, and economic generalization, prioritizing computational metrics over implementation viability. This review highlights the persistent validation–deployment gap in digital agriculture, urging a shift toward multi-tier evaluation frameworks that include contextual, adoption, and impact validation under real deployment conditions. Full article

Generative Artificial Intelligence (GenAI) systems have introduced new classes of security incidents that traditional response frameworks were not designed to manage, ranging from model manipulation and data exfiltration to misinformation cascades and prompt-based privilege escalation. This study proposes a Practical Incident-Response Framework for Generative AI Systems (GenAI-IRF) that bridges established cybersecurity standards with emerging AI assurance principles. Using a Design Science Research (DSR) approach, this study identifies six recurrent incident archetypes and formalises a structured playbook aligned with NIST SP 800-61r3, NIST AI 600-1, MITRE ATLAS, and OWASP LLM Top-10. The artefact was evaluated in controlled scenarios using scenario-based simulations and expert reviews involving AI-security practitioners from academia, finance, and technology sectors. The results suggest high inter-rater reliability (κ = 0.88), strong usability (SUS = 86.4), and improved incident resolution times compared to baseline procedures. The findings demonstrate how traditional response models can be adapted to GenAI contexts using taxonomy-driven analysis, artefact-centred validation, and practitioner feedback. This framework provides a practical foundation for security teams seeking to operationalise AI incident response and contributes to the emerging body of work on trustworthy and resilient AI systems. Full article

Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss; anti-vascular endothelial growth factor (anti-VEGF) therapy is standard care for neovascular AMD (nAMD), yet treatment response varies. We systematically reviewed and meta-analyzed artificial intelligence (AI) and machine learning (ML) models using optical coherence tomography (OCT)-derived information to predict anti-VEGF treatment response in nAMD. PubMed, Embase, Web of Science, and IEEE Xplore were searched from inception to 18 December 2025 for eligible studies reporting threshold-based performance. Two reviewers screened studies, extracted data, and assessed risk of bias using PROBAST+AI; pooled sensitivity and specificity were estimated with a bivariate random-effects model. Seven studies met inclusion criteria, and six were synthesized quantitatively. Pooled sensitivity was 0.79 (95% CI 0.68–0.87), and pooled specificity was 0.83 (95% CI 0.62–0.94), with substantial heterogeneity. Specificity tended to be higher for long-term and functional outcomes than for short-term and anatomical outcomes. Most studies had a high risk of bias, mainly due to limited external validation and incomplete reporting. OCT-based AI models may help stratify treatment response in nAMD, but prospective, multicenter validation and standardized outcome definitions are needed before routine use; current evidence shows no consistent advantage of deep learning over engineered radiomic features. Full article

This critical review explores the transformative impact of artificial intelligence (AI), particularly machine learning (ML) and computer vision (CV), on scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) for metallic microstructure analysis, spanning research from 2010 to 2025. It critically evaluates how AI techniques balance automation, accuracy, and scalability, analysing why certain methods (e.g., Vision Transformers for complex microstructures) excel in specific contexts and how trade-offs in data availability, computational resources, and interpretability shape their adoption. The review examines AI-driven techniques, including semantic segmentation, object detection, and instance segmentation, which automate the identification and characterisation of microstructural features, defects, and inclusions, achieving enhanced accuracy, efficiency, and reproducibility compared to traditional manual methods. It introduces the Microstructure Analysis Spectrum, a novel framework categorising techniques by task complexity and scalability, providing a new lens to understand AI’s role in materials science. The paper also evaluates AI’s role in chemical composition analysis and predictive modelling, facilitating rapid forecasts of mechanical properties such as hardness and fracture strain. Practical applications in steelmaking (e.g., automated inclusion characterisation) and case studies on high-entropy alloys and additively manufactured metals underscore AI’s benefits, including reduced analysis time and improved quality control. Extending prior reviews, this work incorporates recent advancements like Vision Transformers, 3D Convolutional Neural Networks (CNNs), and Generative Adversarial Networks (GANs). Key challenges—data scarcity, model interpretability, and computational demands—are critically analysed, with representative trade-offs from the literature highlighted (e.g., GANs can substantially augment effective dataset size through synthetic data generation, typically at the cost of significantly increased training time). Full article

Background: Artificial intelligence (AI) is reshaping health sciences education worldwide, yet regional data from Latin America remain scarce. Understanding students’ AI literacy and perceptions is essential for developing informed curricular strategies. Methods: A cross-sectional online survey was conducted among 270 students from four Costa Rican universities across five health sciences programs. Descriptive and inferential analyses (ANOVA, Chi-square) examined AI knowledge, usage frequency, and perceptions of ethical integration in academic contexts. Results: Over 80% of respondents reported moderate or higher AI knowledge and frequent use of tools such as ChatGPT, mostly for academic support tasks. However, more than 90% had not received formal institutional training, and ethical awareness—particularly regarding misinformation and bias—was limited. Conclusions: Students demonstrate active engagement with AI despite minimal curricular exposure. These findings emphasize the need for structured AI training, faculty development, and equitable access policies aligned with global digital ethics frameworks to ensure responsible adoption within Costa Rican health sciences education. Full article

Background and Objectives: Subclinical paroxysmal atrial fibrillation (AF) is often undetected by conventional screening strategies, until complications emerge. Artificial intelligence (AI) applied to sinus rhythm electrocardiograms has emerged as a promising tool to identify individuals with occult AF and to predict the risk of future incident AF. This scoping review synthesizes evidence from original studies evaluating AI models trained on sinus rhythm ECGs for AF detection or AF prediction. Materials and Methods: A comprehensive search of MEDLINE, Embase, Web of Science, Scopus, and IEEE Xplore was conducted to identify peer-reviewed studies from inception to November 2025. Eligible studies included original investigations in which the model input was a sinus rhythm ECG and the outcome was either paroxysmal AF or new-onset AF. Extracted variables included cohort characteristics, ECG acquisition parameters, AI architecture, model predictive performance, AF prediction horizon, clinical outcomes, and validation strategy. Risk of bias was assessed using PROBAST. Results: Nineteen studies met the inclusion criteria. Retrospective datasets ranging from several thousand to over one million ECGs and convolutional or deep neural network AI architectures were used in most studies. AI-ECG models demonstrated high diagnostic accuracy for detecting subclinical AF (ten studies; AUROC 0.75–0.90) and for predicting long-term new-onset AF (six studies; AUROC 0.69–0.85) from a single sinus rhythm ECG. Robust external validation was reported in eleven studies. Combining AI-ECG models with clinical risk factors improved AF predictive performance in several reports. Key limitations across studies included retrospective design, patient selection, limited calibration reporting, and sparse prospective impact data. Conclusions: AI-based analysis of sinus rhythm ECGs can detect occult AF and stratify future AF risk with moderate-to-high accuracy across multiple populations and healthcare systems. However, rigorous prospective trials, evaluating clinical benefit, cost-effectiveness, calibration across demographic groups, and real-world implementation, are required before broad adoption in clinical practice. Full article

Background: Head and neck squamous cell carcinoma (HNSCC) remains the seventh most common cancer worldwide, characterized by late-stage diagnosis and poor 5-year survival rates. Oral squamous cell carcinoma (OSCC) is the most prevalent subtype. The identification of robust diagnostic, prognostic, and predictive markers is essential for personalized treatment monitoring. Methods: Following PRISMA and PICO standards, we conducted a comprehensive review of studies published over the past 10 years across PubMed/MEDLINE, Scopus, and Web of Science. The selection process was facilitated by AI-powered tools (Rayyan QCRI), and study quality was assessed using NOS or QUIPS. Results: 34 articles (including meta-analyses and original trials) were identified. Established clinical markers, such as p16-positivity (HR ≈ 0.55) and PD-L1 (CPS), remain significant. However, the molecular landscape is expanding to include high-risk lncRNA signatures (HR ≈ 2.50), immune checkpoints such as TIGIT (HR ≈ 1.85), and genomic alterations, including IL-10 promoter polymorphisms. We highlight that epigenetic silencing of p16 affects only about 25% of patients, while metabolic regulators (e.g., GLUT-1) and protein markers (e.g., MASPIN) offer critical predictive value for therapy response. Conclusions: The diagnostic and predictive paradigm is shifting toward a multi-omic approach that integrates DNA, RNA, proteins, and metabolic indicators. Future clinical use will rely on AI-driven multimarker panels and non-invasive liquid biopsies to enable real-time monitoring and de-escalation of treatment strategies. Full article

In recent years, with the rapid advancement of science and technology, generative artificial intelligence has increasingly entered the public eye. Primarily through intelligent algorithms that simulate human logic and integrate vast amounts of network data, it provides designers with solutions that transcend traditional thinking, enhancing both design efficiency and quality. Compared to traditional design methods reliant on human experience, generative design possesses robust data processing capabilities and the ability to refine design proposals, significantly reducing preliminary design time. This study employs the CiteSpace visualization tool to systematically organize and conduct knowledge map analysis of research literature related to generative AI in architectural design within the Web of Science database from 2005 to 2025. Findings reveal the following: (1) International research exhibits a trend toward interdisciplinary convergence. In recent years, research in this field has grown rapidly across nations, with continuously increasing academic influence; (2) Research primarily focuses on technological applications within architectural design, aiming to drive innovation and development by providing superior, more efficient technical support; (3) Generative AI in architectural design has emerged as a prominent international research focus, reflecting a shift from isolated design to industry-wide integration; (4) Generative AI has become a core global architectural design topic, with future research advancing toward full-process intelligent collaboration. High-quality knowledge graphs tailored for the architecture industry should be constructed to overcome data silos. Concurrently, a multidimensional evaluation system for generative quality must be established to deepen the symbiotic design paradigm of human–machine collaboration. This significantly enhances efficiency while reducing the iterative nature of traditional methods. This study aims to provide empirical support for theoretical and practical advancements, offering crucial references for practitioners to identify business opportunities and policymakers to optimize relevant strategies. Full article

The rapid spread of climate change misinformation across digital platforms undermines scientific literacy, public trust, and evidence-based policy action. Advances in Natural Language Processing (NLP) and Large Language Models (LLMs) create new opportunities for automating the detection and correction of misleading climate-related narratives. This study presents a multi-stage system that employs state-of-the-art large language models such as Generative Pre-trained Transformer 4 (GPT-4), Large Language Model Meta AI (LLaMA) version 3 (LLaMA-3), and RoBERTa-large (Robustly optimized BERT pretraining approach large) to identify, classify, and generate scientifically grounded corrections for climate misinformation. The system integrates several complementary techniques, including transformer-based text classification, semantic similarity scoring using Sentence-BERT, stance detection, and retrieval-augmented generation (RAG) for evidence-grounded debunking. Misinformation instances are detected through a fine-tuned RoBERTa–Multi-Genre Natural Language Inference (MNLI) classifier (RoBERTa-MNLI), grouped using BERTopic, and verified against curated climate-science knowledge sources using BM25 and dense retrieval via FAISS (Facebook AI Similarity Search). The debunking component employs RAG-enhanced GPT-4 to produce accurate and persuasive counter-messages aligned with authoritative scientific reports such as those from the Intergovernmental Panel on Climate Change (IPCC). A diverse dataset of climate misinformation categories covering denialism, cherry-picking of data, false causation narratives, and misleading comparisons is compiled for evaluation. Benchmarking experiments demonstrate that LLM-based models substantially outperform traditional machine-learning baselines such as Support Vector Machines, Logistic Regression, and Random Forests in precision, contextual understanding, and robustness to linguistic variation. Expert assessment further shows that generated debunking messages exhibit higher clarity, scientific accuracy, and persuasive effectiveness compared to conventional fact-checking text. These results highlight the potential of advanced LLM-driven pipelines to provide scalable, real-time mitigation of climate misinformation while offering guidelines for responsible deployment of AI-assisted debunking systems. Full article

Non-digital traditional games such as board and card formats are increasingly recognised as valuable tools for active learning in higher education. These analogue approaches promote engagement, collaboration, and conceptual understanding through embodied and social interaction. This scoping review mapped research on the use of traditional, non-digital games as active learning strategies in tertiary education and examined whether the rise in generative artificial intelligence (GenAI) since 2022 has influenced their pedagogical role. Following the PRISMA-ScR framework, a systematic search of Scopus (October 2025) identified 2480 records; after screening, 26 studies met all inclusion criteria (explicitly using card and/or board games). Whilst this was a scoping, not a systematic review, some bias due to using only one database and evidence could have missed some studies. Results analysed the use and impacts of the games and whether AI was a specific driver in its use. Studies spanned STEM, business, health, and social sciences, with board and card games most frequently employed to support engagement, understanding, and collaboration. Most reported positive learning outcomes. Post-2023 publications suggest renewed interest in analogue pedagogies as authentic, human-centred responses to AI-mediated education. While none directly investigated GenAI, its emergence appears to have acted as an indirect catalyst, highlighting the continuing importance of tactile, cooperative learning experiences. Analogue games therefore remain a resilient, adaptable form of active learning that complements technological innovation and sustains the human dimensions of higher-education practice. Full article

Foundational biomedical sciences are commonly taught without routine integration of local population health contexts, limiting students’ ability to connect mechanisms to community disease burden and practice responsibilities. In this method paper, we developed and piloted an AI-enabled “Sacramento County Public Health (SACPH)” AI workflow and app prototype, a structured, faculty-authored prompt sequence designed to guide population-to-practice reasoning using publicly available data. The workflow was implemented during a TBL session with first-year PharmD students in an immunology course. Using splenectomy and risk of overwhelming post-splenectomy infection (OPSI) as an illustrative use case, students executed a standardized prompt sequence addressing data source identification, coding logic (diagnosis vs. procedure codes), population-level estimation with uncertainty framing, and translation to pharmacist-relevant prevention and counseling implications. Feasibility was defined by conceptual convergence. The validated reasoning workflow was subsequently translated into a prototype, app-style interface using generative design prompts. Across student teams, outputs converged on similar categories, consistent recognition of coding frameworks and verification steps, and directionally similar interpretations of local burden and pharmacist responsibilities. The prototype demonstrated successful externalization of the reasoning workflow into a modular, reproducible artifact. SACPH demonstrates a feasible, reproducible method for using generative AI to integrate foundational science instruction with local population health context and pharmacist practice reasoning, while supporting AI literacy competencies. Full article

The convergence of Artificial Intelligence (AI) and the Internet of Things (IoT), known as Artificial Intelligence of Things (AIoT), has emerged as a transformative paradigm for enabling intelligent, data-driven, and context-aware decision-making in urban environments to reduce the carbon footprint of mobility and industry. This review examines the conceptual foundations, and state-of-the-art developments of AIoT, with a particular emphasis on its applications in smart cities and its relevance to climate change management. AIoT integrates sensing, connectivity, and intelligent analytics to provide optimized solutions in transportation systems, energy management, waste collection, and environmental monitoring, directly influencing urban sustainability. Beyond urban efficiency, AIoT can play a critical role in addressing the global challenges and management of climate change by (a) precise measurements and autonomously remote monitoring; (b) real-time optimization in renewable energy distribution; and (c) developing prediction models for early warning of climate disasters. This paper performs a literature review and bibliometric analysis to identify the current landscape of AIoT research in smart city contexts. Over 1885 articles from Web of Sciences and over 1854 from Scopus databases, published between 1993 and January 2026, were analyzed. The results reveal a strong and accelerating growth in research activity, with publication output doubling in the most recent two years compared to 2023. Waste management and air quality monitoring have emerged as leading application domains, where AIoT-based optimization and predictive models demonstrate measurable improvements in operational efficiency and environmental impact. Altogether, these support faster and more effective decisions for reducing greenhouse gas emissions and ensuring the sustainable use of resources. The reviewed studies reveal rapid advancements in edge intelligence, federated learning, and secure data sharing through the integration of AIoT with blockchain technologies. However, significant challenges remain regarding scalability, interoperability, privacy, ethical governance, and the effective translation of research outcomes into policy and citizen-oriented tools such as climate applications, insurance models, and disaster alert systems. By synthesizing current research trends, this article highlights the potential of AIoT to support sustainable, resilient, and citizen-centric smart city ecosystems while identifying both critical gaps and promising directions for future investigations. Full article

In the context of environmental challenges and digital transformation, artificial intelligence (AI) plays a key role in promoting sustainable development within Industry 4.0 and the emerging paradigm of Industry 5.0. This study systematically reviewed the literature (2015–2025) from Scopus and Web of Science on the connections between AI, circular economy, industrial paradigms, and the Sustainable Development Goals (SDGs), with a particular focus on supply chains and SDG 12—responsible consumption and production. The majority of research emphasizes managerial aspects, the application of machine learning and robotics, as well as waste reduction, resource optimization, and circular economy practices within supply chain and production–consumption systems. Geographical analysis shows that larger economies serve as central research hubs, while some countries that are not among the most populous often achieve the highest average citations per document. Temporal keyword trends indicate a shift in research focus from operational efficiency in traditional supply chains (optimization) toward supply chain digitalization (artificial intelligence) and sustainability (circular economy). Keyword trends reveal four thematic clusters: supply chain digitalization, agritech, smart industry, and sustainability. The study highlights future research directions, including integrating circular economy with managerial and technical approaches, linking Industry 5.0 with SDG 12, and applying advanced AI in sustainable industrial practices. The increasing attention to ethical and social dimensions underscores the need for AI solutions that are both technologically advanced and sustainability oriented. Full article

Agricultural robotics and artificial intelligence (AI) are becoming essential to building more sustainable, efficient, and resilient food systems. As climate change, food security pressures, and labour shortages intensify, the integration of intelligent technologies in agriculture has gained strategic importance. This systematic review provides a consolidated assessment of AI and robotics research in agriculture from 2000 to 2025, identifying major trends, methodological trajectories, and underexplored domains. A structured search was conducted in the Scopus database—which was selected for its broad coverage of engineering, computer science, and agricultural technology—and records were screened using predefined inclusion and exclusion criteria across title, abstract, keywords, and eligibility levels. The final dataset was analysed through descriptive statistics and science-mapping techniques (VOSviewer, SciMAT). Out of 4894 retrieved records, 3673 studies met the eligibility criteria and were included. As with all bibliometric reviews, the synthesis reflects the scope of indexed publications and available metadata, and potential selection bias was mitigated through a multi-stage screening workflow. The analysis revealed four dominant research themes: deep-learning-based perception, UAV-enabled remote sensing, data-driven decision systems, and precision agriculture. Several strategically relevant but underdeveloped areas also emerged, including soft manipulation, multimodal sensing, sim-to-real transfer, and adaptive autonomy. Geographical patterns highlight a strong concentration of research in China and India, reflecting agricultural scale and investment dynamics. Overall, the field appears technologically mature in perception and aerial sensing but remains limited in physical interaction, uncertainty-aware control, and long-term autonomous operation. These gaps indicate concrete opportunities for advancing next-generation AI-driven robotic systems in agriculture. Funding sources are reported in the full manuscript. Full article

Background/Objectives: Cancer pain affects 55–95% of patients with advanced malignancy, representing a complex syndrome involving nociceptive, neuropathic and nociplastic mechanisms. Despite therapeutic advances, two-thirds of patients with metastatic cancer experience inadequate pain control. This scoping review synthesizes recent advances in cancer pain pathophysiology and management, focusing on molecular and cellular mechanisms, emerging pharmacological, interventional and technological therapies and key evidence gaps to inform future precision-based pain management strategies. Methods: Following PRISMA-ScR methodology, we searched PubMed, Embase, Scopus, and Web of Science for studies published between January 2022 and September 2025. After screening 3412 records, 278 studies were included and analyzed across different domains: biological mechanisms, pharmacological management, interventional and neuromodulatory approaches, radiotherapy developments, and digital health innovations. Results: Recent mechanistic research reveals cancer pain arises from tumor–neuron–immune crosstalk, with malignant cells secreting neurotrophic factors that promote axonal sprouting and nociceptor sensitization. Genetic polymorphisms and epigenetic modifications contribute to inter-individual pain variability. Management strategies are evolving toward multimodal precision medicine: NSAIDs and opioids remain foundational, complemented by adjuvant agents and interventional procedures including nerve blocks, intrathecal delivery, and neuromodulation (spinal cord and dorsal root ganglion stimulation). Stereotactic body radiotherapy demonstrates superior analgesic durability versus conventional approaches. Digital health innovations, such as mobile applications, remote monitoring, wearables, and AI-enabled predictive models, enable continuous assessment and personalized treatment optimization. Conclusions: Cancer pain management is transitioning toward mechanism-based precision medicine integrating biological insights, advanced interventional techniques, and digital technologies. However, implementation challenges persist, including limited randomized trials for interventional approaches, the incomplete external validation of AI tools, and digital health equity concerns. Future research must prioritize prospective controlled studies and equitable integration into routine care. Full article