Search Results (5,106)

Summer overheating is an escalating challenge for lightweight timber constructions, which inherently lack the thermal mass of traditional masonry. This study investigates the thermo-physical properties of a mycelium-based biocomposite (MBB) insulation produced from industrial wood waste, with particular focus on volumetric heat capacity (C_v). The C_v and thermal conductivity (λ) of MBB were experimentally measured and benchmarked against seven reference insulation materials spanning bio-based, mineral, and petroleum-derived categories, with results visualized on an Ashby diagram. The areal heat capacity (κ) of nine representative wall assemblies was theoretically calculated per EN ISO 13786. Even though the MBB achieved the highest thermal conductivity (λ = 0.0641 ± 0.0024 W·m⁻¹·K⁻¹) among the tested insulation materials, it offers 4.7 times higher C_v than EPS. Analytical modeling indicates a thermal phase shift of 8.2 h for a 185 mm layer, compared to 4.6 h for EPS. The softwood timber + MBB wall assembly achieved an areal heat capacity approaching the lower boundary of traditional masonry performance. These findings demonstrate MBB’s potential as a bio-based, waste-derived insulation for significantly enhancing the thermal inertia of lightweight timber buildings and mitigating summer overheating risk. Full article

Background: Although pre-exposure prophylaxis (PrEP) is highly effective for HIV prevention, identifying individuals who may benefit from PrEP and delivering personalized prevention recommendations remain challenging in routine and digital health settings. Objective: This study aimed to develop and preliminarily evaluate an integrated artificial intelligence framework combining machine learning (ML) for HIV risk stratification and generative artificial intelligence (GenAI) for personalized PrEP recommendation support. Methods: A curated dataset of 2000 de-identified client profiles from Love2Test platform was used for proof-of-concept model development. Profiles were labeled as low or high HIV acquisition risk by domain experts based on structured behavioral information. Multiple ML classifiers were trained and compared using PyCaret. The selected model was integrated with a generative AI model through structured prompting to generate personalized PrEP recommendation content. The integrated framework was evaluated through structured physician assessment by four independent medical doctors. Results: The selected model showed strong internal discrimination for classifying high versus low HIV acquisition risk. The integrated framework also received favorable physician evaluation for clinical accuracy, explanation validity, contextual relevance, and error minimization across fixed and randomly selected profiles. However, because expert labeling was based on structured behavioral indicators closely related to the model inputs, the high internal performance should be interpreted within the context of this proof-of-concept study. Conclusions: The proposed framework provides a structured approach to support HIV risk stratification and personalized PrEP recommendations in a clinician-aligned manner. However, this study was an offline proof-of-concept and did not directly evaluate patient interaction, PrEP uptake, stigma, adherence, or clinical outcomes. Prospective studies using larger and more representative real-world datasets are needed to assess implementation, generalizability, and impact on service engagement and PrEP initiation. Full article

Under extreme steady-state temperature gradients, external thermal insulation composite systems (ETICSs) are prone to thermal deformation, which can cause mortar cracking, hollowing, and even delamination and detachment of insulation boards, thus degrading building envelope performance and threatening structural and personal safety. In this study, a combined method of numerical simulation using ANSYS software and experimental testing was adopted to investigate the thermal deformation characteristics of three commonly used insulation materials: Expanded Polystyrene (EPS), Extruded Polystyrene (XPS), and Polyurethane (PU). The effects of temperature difference from 10 °C to 30 °C, insulation board thickness from 30 mm to 100 mm, and surface mortar thickness from 5 mm to 10 mm on strain distribution and deformation mechanism were systematically analyzed. Experimental validation showed good agreement with the simulation results, quantified by an estimated relative error of less than 15% across the investigated insulation thicknesses and steady-state temperature conditions. The results indicate that the strains of EPS, XPS, and PU boards all increase significantly as the temperature difference across the board rises. Under outdoor temperatures of 30 °C, 40 °C and 50 °C with a constant indoor temperature of 20 °C, the thickness-direction strain at the EPS–mortar interface increases by approximately 35% when the temperature difference increases from 10 °C to 30 °C. Increasing both insulation board thickness and mortar protective layer thickness effectively reduces thermal deformation. Specifically, when the EPS board thickness increases from 30 mm to 100 mm, the thickness-direction strain decreases by approximately 73%; and when the mortar thickness increases from 5 mm to 10 mm, the interfacial strain decreases by approximately 32%. Due to differences in linear expansion coefficients, the three insulation materials exhibit distinctly different thermal deformation behaviors, with the thickness-direction strain following the order EPS > XPS > PU. These findings provide a theoretical basis and data support for material selection, structural optimization, and safety design of external wall insulation systems. Full article

Conventional epoxy adhesives used in motor insulation structures still suffer from insufficient thermal resistance and difficulty in balancing heat resistance with mechanical reliability. In this study, BMI-modified E-51/MeHHPA/EMI-24 epoxy composites were prepared and evaluated as heat-resistant interfacial adhesives for simulated F-class pole windings. BMI/EP composites with different BMI contents were fabricated by melt blending and characterized in terms of curing kinetics, FTIR, mechanical properties, and thermal performance. The optimized formulation was then applied to bond Nomex insulation paper to the upright plate in a simulated pole winding. The results showed that BMI did not alter the main epoxy/anhydride curing pathway, but restricted segmental motion and improved thermal resistance. The 10phr BMI/EP composite exhibited a favorable balance among thermal performance, mechanical properties, and fracture morphology. The simulated winding prepared with this formulation showed no breakdown or flashover under 6800 V/60 s, with an insulation resistance of 64.49 GΩ. A lower-bound apparent temperature index of approximately 157 °C was obtained using the TGA-derived thermal life equation. These results indicate that this system has preliminary application potential as a heat-resistant interfacial adhesive for F-class motor winding insulation, although a complete thermal life assessment is still required. Full article

Against the backdrop of coordinated development in the Beijing–Tianjin–Hebei region, Hebei Province serves as an ecological safety barrier for the Beijing–Tianjin–Hebei urban agglomeration. Conducting research on land use and land cover change (LUCC) and ecosystem service value (ESV) holds significant theoretical and practical value for elucidating the mechanisms underlying ESV evolution under the combined effects of rapid urbanization and major ecological engineering projects, and for applying these findings to regional land-use planning and ecological conservation and restoration efforts. This research aligns with the United Nations Decade on Ecosystem Restoration (2020–2030). Based on land-use data from 2000, 2010, and 2020, along with 11 categories of natural and socio-economic drivers, this study systematically analyses regional LUCC and calculates ESV using locally adjusted equivalence factors. It examines the spatiotemporal evolution patterns of ESV through the analysis of local spatial autocorrelation indices (LISAs), centroid, and standard deviation ellipses, and employs a GeoDetector to measure ESV drivers. Three scenarios—a natural evolution scenario (NES), economic development scenario (EDS), and ecological protection scenario (EPS)—were established. The patch-generating Land use simulation (PLUS) model was employed to simulate LUCC for 2030 (Kappa = 0.840) and calculate ESV. Results show that from 2000 to 2020, forest land and impervious surfaces in Hebei Province continued to expand, while cropland and grassland decreased. The cumulative ESV increased by 4.85 billion yuan. Slope was the primary driver of spatial variation in ESV, and the interaction between natural and socioeconomic factors demonstrated significantly stronger explanatory power. In 2030, the total ESV under all three scenarios was lower than in 2020. The EPS reached an ESV of 344.72 billion yuan, representing a relatively suitable model that balances development and conservation. Full article

Background/Objectives: Melanoma affects both sexes, and its incidence has increased in recent years. It is currently among the most common types of cancer. Standard chemotherapy, although effective, often lacks selectivity for tumor cells, resulting in dose-limiting side effects. Electrochemotherapy and magnetic hyperthermia have been investigated as innovative biomedical approaches. Electrochemotherapy improves drug delivery by facilitating electroporation, thereby increasing intracellular concentrations of chemotherapeutic agents and reducing associated adverse effects. Furthermore, electroporation enhances sensitivity to magnetic hyperthermia. However, few studies have focused on the combination of electroporation and hyperthermia in melanoma models. This study aimed to evaluate the synergistic effects of intratumoral administration of superparamagnetic iron oxide nanoparticles (SPIONs), electroporation (EP), and magnetic hyperthermia (EHP) on fluorescent melanoma tumors generated with the MV3-GFP cell line. Methods: Fluorescent melanoma tumors were generated using the MV3-GFP cell line. Treatments included SPIONs alone, SPIONs combined with hyperthermia, and SPIONs combined with electroporation and hyperthermia. Tumor size was monitored over 21 and 28 days. Results: SPIONs alone did not affect tumor growth (665 mm³). SPIONs plus hyperthermia reduced tumor size to 126.5 mm³ at day 21. The combination of SPIONs, electroporation, and hyperthermia produced a pronounced antitumoral effect, with tumor size decreasing to 95.5 mm³ at day 14 and 6.8 mm³ at day 21, followed by complete tumor disappearance by day 28. Electroporation significantly enhanced the antitumoral activity of the combined treatment. Conclusions: The combination of SPIONs, electroporation, and magnetic hyperthermia shows significant synergistic antitumoral activity in a melanoma model. These findings support further investigation in larger and more comprehensive in vivo studies to better understand the therapeutic potential of these combined approaches. Full article

Soil water retention is a key factor in ecological processes regulating ecosystem stability and resilience under environmental stress. In this regard, marine-derived additives may provide sustainable strategies to enhance soil water dynamics. Here, novel biopolymers derived from thermophilic bacteria, including six exopolysaccharides (EPS1–EPS6) and four biosurfactants (BS1-BS4), and biomasses from seaweed (BM1–BM4) and marine cyanobacteria (BC1–BC2), were investigated for their wetting properties and soil water retention. Wetting properties, including reduction in contact angle (RCA) and atmospheric-air moisture uptake (AMU), were monitored for 36 h at constant temperature (30 °C). The effect on soil water retention was evaluated in terms of water loss of soil samples treated with two different concentrations (0.5 and 1% w/w) of either biopolymers or biomasses in a microcosm consisting of 10 g of soil and 10 mL of water, kept at a stable temperature of 22 °C for 200 h (until complete evaporation occurred). BC2 derived from Leptolyngbya sp. 43.3 was the best wetting agent (RCA = 39.44%), while the EPS4 produced by Bacillus horneckiae SBP3 was the best humectant agent (AMU = 179.63%). Soils amended with bacterial biopolymers (EPS4, EPS5, EPS6, BS1 and BS3), as well as biomasses derived from cyanobacteria BC2 and seaweed BM1–BM4, produced better improvement in soil water retention, with marked effects at the concentration of 1% w/w. The lipopeptide BS1 was the most effective in water loss reduction over a specific time of 96–125 h at both concentrations. These findings highlight the potential of these materials as nature-based solutions to improve soil-mediated ecosystem resilience to drought under climate change. Full article

This study critically addresses the challenge of selecting optimal insulation materials for contemporary, energy-efficient building envelopes, a decision with profound environmental, structural, and occupational health consequences. The paper responds to the growing demand for sustainable, resilient solutions by comparing wool, a bio-based, regenerative material, and expanded polystyrene (EPS), a synthetic polymer widely implemented in the construction industry, and advanced laboratory testing (thermal conductivity, moisture buffering, freeze–thaw resistance) is discussed in a comprehensive synthesis of the recent literature. Also, field evaluations from European retrofits and pilot projects (UK, Denmark, Finland, Iceland, Norway, Sweden, Germany and France) further contextualize performance outcomes, and life cycle impacts are considered. Recent results reveal that wool insulation achieves a moisture buffering value (MBV) between 1.8 and 2.7 (g/m²) % RH, minimal vapor resistance (mvr = 1–2), and preserves functional and structural integrity through more than 100 freeze–thaw cycles, leading to significant stabilization of the interior microclimate and enhanced durability. In contrast, EPS delivers lower thermal conductivity (0.032–0.037 (W/mK), critical for reducing heating/cooling demand, but exhibits limited vapor permeability (lvp = 60–150 MN·s/(g·m)), increased risk of condensation and mold, and reduced compressive strength (<22% after 30 cycles), especially when ventilation details are inadequate. Hybrid envelope systems leveraging both EPS and wool are demonstrated to optimize energy efficiency (up to 23% seasonal savings) and reduce interior humidity fluctuations, while lifecycle and recycling assessments show wool panels to be markedly superior in carbon footprint reduction and circularity. The stratification of insulation layers incorporating wool for vapor and moisture control, and EPS for pure thermal resistance is emerging as best practice in sustainable retrofit and new-build projects. Recommendations highlight the necessity for rigorous laboratory validation, international standards alignment, and integrated material design for robust hygrothermal comfort and environmental performance. The review also covers wool- and EPS-based hybrid composites, showing how natural fibers can improve key mechanical properties without compromising thermal insulation performance or environmental benefits. Full article

Background/Objectives: Air pollution is associated with many adverse health consequences, including deteriorated kidney function. The aim of the research was to determine the association of medium-term exposure to air pollutants and hospitalizations due to acute kidney injury (AKI). Methods: The retrospective population-based study was conducted on the EP-PARTICLES cohort between 2011 and 2020 (80,000,000 person-years). We estimated municipality-specific associations between air pollution and AKI admissions using generalized additive models with Poisson regression. Results are reported as risk ratio in AKI admissions (RR) with corresponding 95% confidence intervals (95% CI). Results: During the 10-year study period, 47,467 AKI cases were reported (median age 77 years, IQR 68–84; 51.2% women). Mean concentrations of pollutants were 21.4 µg/m³ (SD 5.2) for particulate matter with a diameter of 2.5 μm or less (PM_2.5), 7.5 µg/m³ (1.8) for nitrogen dioxide (NO₂), and 1.8 ng/m³ (0.8) for benzo[a]pyrene (BaP). In mid-term exposure analyses (lag 0–30), each 10 µg/m³ increase in PM_2.5, PM₁₀, NO₂ and CO, and each 1 µg/m³ increase in BaP, was associated with higher AKI risk, with the strongest effect observed for NO₂ (RR 1.066, 95% CI 1.033–1.099). No association was found for SO₂. Subgroup analyses showed consistent directions of association across sex and age groups, with NO₂ remaining the most detrimental pollutant. Although statistical significance varied between pollutants, no significant effect modification by sex or age was observed (p > 0.05). Conclusions: Mid-term exposure to ambient air pollution is associated with an increased risk of AKI-related hospitalizations, with NO₂ showing the strongest effects. These findings identify mid-term exposure as a relevant temporal window and support the role of air pollution as a modifiable risk factor for AKI. Full article

Plastic pollution in terrestrial and freshwater environments and its accumulation along food chains has been poorly studied in birds. In this paper we reported evidence of microplastic (MP) contamination in pellets collected in rural and urban sites for a set of species: common kestrel, Falco tinnunculus; great cormorant, Phalacrocorax carbo; barn owl, Tyto alba; little owl, Athene noctua; long-eared owl, Asio otus; Eurasian scops owl, Otus scops; European bee-eater, Merops apiaster; and little egret, Egretta garzetta. A total of 559 pellets were collected and analyzed; among them, 78 microplastics were found on 77 pellets (13.8% compared to the total number of pellets sampled). The following polymers were recorded: polyvinylchloride (PVC), polyethylene (PE), expanded polyester (EPS), polyethylene terephthalate (PET), polybutylene terephthalate (PBT), polyester (PES), polymethyl acrylate (PMA), rubber, and starch-based biopolymer. We found significantly higher MP frequency in the most anthropized site. Pellets with the highest number of microplastics were those produced by Falco tinnunculus, Asio otus, and Tyto alba, with 30.0%, 29.6%, and 27.1%, respectively. Of a total sample of 78 MP items, 59.0% are represented by fibers, 23.1% by fragments and 17.9% by films. Among the microplastics, fragments of balloons (in a remote area) and biopolymer shopping bags were found. Our results suggest that pellet analysis may represent a cost-effective method for monitoring MP contamination along food chains in terrestrial ecosystems. Full article

Ultra-high-voltage direct-current (UHVDC) transmission systems impose stringent requirements on the reliability of insulation materials used in converter transformer bushings. Epoxy resin systems are key insulating materials in resin-impregnated paper (RIP) capacitor bushings, and their processing characteristics, curing behavior, and electrical properties directly affect bushing performance. In this study, two epoxy insulation systems used for resin-impregnated paper (RIP) bushings, namely the imported Araldite LY1564/Aradur 3486 system and the domestic EP-2020/CA-3015 system, were systematically investigated through viscosity, curing, and electrical property tests. The results show that the viscosities of both resins decreased significantly with increasing temperature. At 60 °C, the viscosities of Resin A and Resin B were 151.6 mPa·s and 156.3 mPa·s, respectively. The mixed resin–hardener systems exhibited similar viscosity evolution and comparable pot life characteristics. DSC measurements revealed two-stage curing reactions for both materials, with first exothermic peak temperatures of 65.4 °C and 96.3 °C and second peak temperatures of 269.3 °C and 269.8 °C for Materials A and B, respectively. Electrical testing demonstrated that both materials exhibited similar temperature-dependent dielectric and resistivity behavior, with dielectric loss increasing at elevated temperatures and resistivity decreasing as temperature increased. The volume resistivity trends and dielectric characteristics of the two materials remained highly consistent throughout the investigated temperature range. The results indicate that Material B exhibits processing performance, curing characteristics, and electrical insulation properties comparable to those of Material A. Therefore, Material B demonstrates strong potential for application in UHVDC RIP bushing insulation systems and provides a promising alternative for the localization of key insulating materials. Full article

The increasing demand for lithium (Li), cobalt (Co), and rare earth elements (REEs) driven by battery technologies, electrification and renewable energy systems has intensified the interest in recovery pathways as an alternative to conventional mining. High-salinity mine waters—including lithium brines, geothermal fluids, and metallurgical effluents—represent both an environmental liability and a significant secondary resource for metal recovery. However, extreme ionic strength, complex metal speciation, and strong competition from major ions severely limit the efficiency and selectivity of traditional extraction technologies. Microalgae and cyanobacteria are promising biological agents for metal recovery via biosorption, bioaccumulation, and extracellular polymeric substance (EPS)-mediated binding, especially in saline and hypersaline systems. This review synthesises current knowledge on microalgal-based recovery of Li, Co, and REEs from high-salinity waters, emphasising co-design principles that integrate strain physiology, their adaptation to the extreme operating conditions, water chemistry, and process engineering. Halotolerant and extremophilic taxa—Nannochloropsis oceanica, Galdieria sulphuraria, and Synechococcus elongatus—are examined as representative models for complementary metal-binding mechanisms and operational niches. Limitations such as weak affinity for lithium, competitive ion suppression, desorption inefficiencies, and scale-up challenges are discussed. Emerging strategies such as modular multi-strain systems, hybrid bio-physicochemical platforms, and biomass valorisation are also addressed. The review concludes that microalgal systems, when co-designed for selectivity and resilience, can contribute to the strategic recovery of critical materials that align with EU, UK and US policies. Full article

Geopolymer EPS concrete (GEPSC) is a promising low-carbon lightweight material for building envelope and thermal insulation applications. In order to investigate the effects of expanded polystyrene (EPS) content on the lightweight characteristics and mechanical properties of geopolymer EPS concrete (GEPSC), specimens with EPS volume contents of 30%, 35%, 40%, 45%, 50%, and 55% were prepared. Dry density, cube compressive strength, axial compressive strength, splitting tensile strength, flexural strength, and elastic modulus were tested, and empirical relationships among the main mechanical parameters were established. The results show that dry density, cube compressive strength, axial compressive strength, splitting tensile strength, and elastic modulus decrease with increasing EPS content, indicating a clear lightweighting–strength reduction effect. The low strength and low stiffness of EPS particles weaken the continuity and load-bearing skeleton of the geopolymer matrix, while promoting more dispersed crack propagation and a more gradual failure process. The correlation coefficients of the proposed empirical models are all greater than 0.90. Lightweighting efficiency analysis indicates that an EPS content of 40–45% provides a favorable balance among weight reduction, strength retention, and stiffness retention. Compared with EPS concrete, GEPSC exhibited 23.5–49.5% higher strength at the same density grade, indicating its good strength retention capacity and potential engineering applicability. These findings support mix optimization, mechanical parameter selection, and engineering application of low-carbon lightweight envelope materials. Full article

Determining the distribution of phosphorus forms in dewatered sludge is crucial, as it directly impacts the choice and effectiveness of recovery strategies. Analyses using the Standards, Measurements and Testing (SMT) method, soluble/insoluble fractionation and extracellular polymeric substance (EPS)/EPS-residue fractionation revealed that sludge characteristics strongly influenced phosphorus speciation and content. Inorganic phosphorus (IP) was the dominant form in dewatered sludge, primarily regulated by the levels of Al, Fe, and Ca, while dissolved orthophosphate (ortho-P) constituted only 1% of the total phosphorus (TP). Notably, phosphorus exhibited a distinct distribution pattern between EPS and EPS residues: EPS comprised only 2.09% of TP, 74.19% of which was organic phosphorus (OP), whereas EPS residues contained 93.26% of TP, with a much lower OP proportion (15.04%). These results indicate that most phosphorus in dewatered sludge is retained in insoluble and residue-bound forms. Therefore, pretreatment strategies that promote the conversion of solid-phase phosphorus into dissolved ortho-P are necessary for improving phosphorus recovery from dewatered sludge, supporting waste valorization and more sustainable sludge management. Full article

Convectively Coupled Kelvin Waves (CCKWs) play a key role in synoptic variability and can trigger extreme hydrometeorological events. This study characterizes the influence of CCKWs on seasonal precipitation patterns and extreme precipitation events (EPEs) over northern South America. Using a filtered OLR dataset, we found that precipitation anomalies associated with CCKWs are sensitive to the selected index region. A sensitivity analysis identified a region in the Colombian Pacific exhibiting the strongest precipitation anomalies linked to CCKWs. At seasonal scales, March–May (MAM) is the season with the highest CCKW activity, and its convective phase is associated with enhanced precipitation over the far eastern Pacific, western Amazonia, and northern Colombia, while suppressed convection dominates northwestern Brazil. In addition, three regions exhibit increases of up to 30% in EPE occurrence during convective-phase Kelvin waves: (i) the northwestern Amazon, (ii) northwestern Colombia, and (iii) the Peruvian coast. In contrast, EPE occurrence in the Colombian Pacific appears largely independent of CCKW passage, likely due to the strong background climatological rainfall in the region. We also analyze a flooding event in Turbo, Colombia, on 9 May 2007, that occurred during the passage of a convective-phase Kelvin wave and was preceded by days of enhanced low-level southwesterly flow convergence and persistent rainfall. Understanding the influence of these intraseasonal oscillations on precipitation and EPEs is essential for improving regional weather forecasts and supporting the development of early warning systems. Full article