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57 Results Found

  • Article
  • Open Access
10 Citations
5,304 Views
14 Pages

Precise Fabrication of Porous Microspheres by Iso-Density Emulsion Combined with Microfluidics

  • Yuxiao Shi,
  • Xin Zhang,
  • Ketao Mu,
  • Yifan Wang,
  • Ting Jiang,
  • Shangtong Jiang,
  • Shengmin Zhang and
  • Yingying Du

30 June 2022

Polymer porous microspheres with large specific surface areas and good fluidity have promising important applications in the biomedical field. However, controllable fabrication of porous microspheres with precise size, morphology, and pore structure...

  • Article
  • Open Access
2 Citations
1,691 Views
29 Pages

Background/Objectives: The management of ocular tumours is faced with the challenge of developing a suitable treatment strategy with consideration of the anatomical and physiological protective barriers of the eye. Interferon alpha has been employed...

  • Article
  • Open Access
29 Citations
4,675 Views
16 Pages

Development of a Thymoquinone Polymeric Anticancer Nanomedicine through Optimization of Polymer Molecular Weight and Nanoparticle Architecture

  • Suhair Sunoqrot,
  • Malek Alfaraj,
  • Ala’a M. Hammad,
  • Violet Kasabri,
  • Dana Shalabi,
  • Ahmad A. Deeb,
  • Lina Hasan Ibrahim,
  • Khaldoun Shnewer and
  • Ismail Yousef

Thymoquinone (TQ) is a water-insoluble natural compound isolated from Nigella sativa that has demonstrated promising chemotherapeutic activity. The purpose of this study was to develop a polymeric nanoscale formulation for TQ to circumvent its delive...

  • Article
  • Open Access
17 Citations
3,955 Views
19 Pages

This investigation focused on the design of an injectable nano-enabled thermogel (nano-thermogel) system to attain controlled delivery of p11 anti-angiogenic peptide for proposed effective prevention of neovascularisation and to overcome the drawback...

  • Article
  • Open Access
3 Citations
3,655 Views
23 Pages

A Single Injection with Sustained-Release Microspheres and a Prime-Boost Injection of Bovine Serum Albumin Elicit the Same IgG Antibody Response in Mice

  • Renée S. van der Kooij,
  • Martin Beukema,
  • Anke L. W. Huckriede,
  • Johan Zuidema,
  • Rob Steendam,
  • Henderik W. Frijlink and
  • Wouter L. J. Hinrichs

Although vaccination is still considered to be the cornerstone of public health care, the increase in vaccination coverage has stagnated for many diseases. Most of these vaccines require two or three doses to be administered across several months or...

  • Article
  • Open Access
6 Citations
2,751 Views
15 Pages

Block Copolymer Micelles Encapsulating Au(III) Bis(Dithiolene) Complexes as Promising Nanostructures with Antiplasmodial Activity

  • Joana F. Santos,
  • Raquel Azevedo,
  • Miguel Prudêncio,
  • Fernanda Marques,
  • Yann Le Gal,
  • Dominique Lorcy and
  • Célia Fernandes

Block copolymer micelles (BCMs) can be used to improve the solubility of lipophilic drugs and increase their circulation half-life. Hence, BCMs assembled from MePEG-b-PCL were evaluated as drug delivery systems of gold(III) bis(dithiolene) complexes...

  • Article
  • Open Access
9 Citations
2,726 Views
20 Pages

4 April 2023

The physical and chemical properties of tissue engineering scaffolds have considerable effects on the inflammatory response at the implant site in soft tissue repair. The development of inflammation-modulating polymer scaffolds for soft tissue repair...

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